研究者詳細 - 八谷　寛

論文 - 八谷　寛

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Mortality and incidence rates of stomach cancer in the JACC Study. 査読有り Open Access

J Epidemiol 15 巻 ( S2 ) 頁： S89-S97 2005年

Dietary habits and stomach cancer risk in the JACC Study. 査読有り Open Access

Tokui N, Yoshimura T, Fujino Y, Mizoue T, Hoshiyama Y, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Kubo T, Tamakoshi A; JACC Study Group.

J Epidemiol 15 巻 ( S2 ) 頁： S98-S108 2005年

Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan. 査読有り

Wakai K, Tamakoshi K, Date C, Fukui M, Suzuki S, Lin Y, Niwa Y, Nishio K, Yatsuya H, Kondo T, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A; JACC Study Group.

Cancer Sci 96 巻 ( 9 ) 頁： 590-599 2005年

Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study. 査読有り

Niwa Y, Yatsuya H, Tamakoshi K, Nishio K, Kondo T, Lin Y, Suzuki S, Wakai K, Tokudome S, Yamamoto A, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

J Obstet Gynaecol Res 31 巻 ( 5 ) 頁： 452-458 2005年

職域コホート男性における血清レプチン濃度と生活習慣との関連査読有り Open Access

63 巻頁： 1284-1288 2005年

Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan. 査読有り

Wakai K, Tamakoshi K, Date C, Fukui M, Suzuki S, Lin Y, Niwa Y, Nishio K, Yatsuya H, Kondo T, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A; JACC Study Group.

Cancer Sci 96 巻 ( 9 ) 頁： 590-599 2005年

Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study. 査読有り

Niwa Y, Yatsuya H, Tamakoshi K, Nishio K, Kondo T, Lin Y, Suzuki S, Wakai K, Tokudome S, Yamamoto A, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

J Obstet Gynaecol Res 31 巻 ( 5 ) 頁： 452-458 2005年

出生時体重と成人期の生活習慣病との関連－胎児期起源仮説－招待有り

玉腰浩司、八谷寛、大塚礼、和田恵子、張恵明、豊嶋英明.

現代医学 52 巻頁： 321-325 2005年

突然死と性差招待有り

玉腰浩司、豊嶋英明、八谷寛.

日本臨床 63 巻頁： 1284-1288 2005年

肥満の健康影響招待有り

八谷寛、玉腰浩司、豊嶋英明.

現代医学 52 巻頁： 521-526 2005年

肥満の科学的解明とエビデンスに基づいた対策・指導招待有り

八谷寛、松下邦洋、玉腰浩司、大塚礼、和田恵子、豊嶋英明.

産業医学レビュー 18 巻頁： 71-116 2005年

Association of white blood cell count and clustered components of metabolic syndrome in Japanese men. 査読有り Open Access

Nagasawa N, Tamakoshi K, Yatsuya H, Hori Y, Ishikawa M, Murata C, Zhang H, Wada K, Otsuka R, Mabuchi T, Kondo T, Toyoshima H.

Circ J 68 巻 ( 10 ) 頁： 892-7 2004年

Individual and joint impact of family history and Helicobacter pylori infection on the risk of stomach cancer: a nested case-control study. 査読有り

Yatsuya H, Toyoshima H, Tamakoshi A, Kikuchi S, Tamakoshi K, Kondo T, Mizoue T, Tokui N, Hoshiyama Y, Sakata K, Hayakawa N, Yoshimura T; Japan Collaborative Cohort Study Group.

British Journal of Cancer 91 巻 ( 5 ) 頁： 929-934 2004年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

We used 202 cases of stomach cancer and 394 controls nested within the Japan Collaborative Cohort Study For Evaluation of Cancer Risk (JACC study) to investigate whether family history has an independent effect on the risk of stomach cancer after controlling for the Helicobacter pylori infection. A positive history of stomach cancer in one or more first-degree relatives was associated with an increased risk of the disease in women, but not in men after controlling for H. pylori infection and other confounding variables. Women with both a family history and H. pylori infection were associated with more than five-fold increased risk of the disease (OR 5.10, 95% CI 1.58-16.5) compared to those without these factors. These results suggest the existence of inherited susceptibility to the disease in women, and that measurements of H. pylori infection together with the family history allow meaningful evaluation of risk beyond that provided by either factor alone.

Serum phospholipid transfer protein mass as a possible protective factor for coronary heart diseases. 査読有り Open Access

Yatsuya H, Tamakoshi K, Hattori H, Otsuka R, Wada K, Zhang H, Mabuchi T, Ishikawa M, Murata C, Yoshida T, Kondo T, Toyoshima H.

Circulation Journal 68 巻 ( 1 ) 頁： 11-16 2004年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND: Phospholipid transfer protein (PLTP) can generate pre-beta high-density lipoprotein (HDL), an efficient acceptor of peripheral cholesterol, by mediating a process called HDL conversion. The transfer of phospholipids to immature HDL is also essential in maintaining reverse cholesterol transport. The phospholipid transfer activity of PLTP has been associated with various patho-physiological conditions; however, little information is available concerning the relationship between PLTP mass and disease. METHODS AND RESULTS: Using a sandwich enzyme-linked immunosorbent assay, PLTP concentration was measured and related to the risk of developing cardiovascular disease in a worksite-based cohort of Japanese men (n=2,567). Multiple linear regression analysis showed significant associations between PLTP and HDL cholesterol, triglycerides, low-density lipoprotein cholesterol, and body mass index (standardized beta=0.395, -0.191, -0.064, and -0.064, respectively; R(2)=0.31). During the follow-up period, there were 10 cases of coronary heart disease (CHD) and 7 of stroke. The multivariate adjusted relative risk of CHD was 0.46 (95% confidence interval, 0.20-1.07) for an increase of 1 standard deviation in the PLTP value (p=0.071). PLTP concentration was not related to the risk of stroke. CONCLUSIONS: The results of this prospective study indicate that the serum PLTP concentration would serve as a predictor of CHD, independent of HDL cholesterol, triglycerides and other established risk factors.

DOI： 10.1253/circj.68.11

Open Access

A nested case-control study of stomach cancer in relation to green tea consumption in Japan. 査読有り

Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Ohno Y, Yoshimura T; Japan Collaborative Cohort Study Group.

Br J Cancer 90 巻 ( 1 ) 頁： 135-8 2004年

A prospective study of body size and colon cancer mortality in Japan: The JACC Study. 査読有り

Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Ito Y, Tamakoshi A; JACC Study Group.

Int J Obes Relat Metab Disord 28 巻 ( 4 ) 頁： 551-8 2004年

A prospective study on the possible association between having children and colon cancer risk: findings from the JACC Study. 査読有り

Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Ito Y, Tamakoshi A; JACC Study Group.

Cancer Sci 95 巻 ( 3 ) 頁： 243-7 2004年

A prospective study of reproductive and menstrual factors and colon cancer risk in Japanese women: findings from the JACC study. 査読有り

Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Suzuki S, Kawado M, Ozasa K, Ito Y, Tamakoshi A; JACC Study Group.

Cancer Sci 95 巻 ( 7 ) 頁： 602-7 2004年

肥満者における心血管疾患発症の過剰リスクを説明する新しい軸－血清レプチン値と白血球数の関連－招待有り

八谷寛, 淵智子, 大塚礼, 和田恵子, 長澤伸江, 張恵明, 村田千代栄, 石川美由紀, 堀容子, 近藤高明, 玉腰浩司, 豊嶋英明.

健康管理事業団研究助成論文集 10 巻頁： 19-25 2004年

人間ドックの有効性と限界招待有り

玉腰浩司, 八谷寛, 豊嶋英明.

総合臨床 53 巻頁： 2435-2438 2004年

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