研究者詳細 - 八谷　寛

論文 - 八谷　寛

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Risk Factor of Cardiovascular Disease Among Older Individuals 査読有り国際誌

Yatsuya, H; Matsunaga, M; Li, YY; Ota, A

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS 24 巻 ( 3 ) 頁： 258 - 261 2017年

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN) 査読有り

Yoichiro Hirakawa, the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Toshiharu Ninomiya, Yutaka Kiyohara, Yoshitaka Murakami, Shigeyuki Saitoh, Hideaki Nakagawa, Akira Okayama, Akiko Tamakoshi, Kiyomi Sakata, Katsuyuki Miura, Hirotsugu Ueshima, Tomonori Okamura, Yutaka Imai, Takayoshi Ohkubo, Fujiko Irie, Hiroyasu Iso, Akihiko Kitamura, Takeo Nakayama, Toshimi Sairenchi, Ichiro Tsuji, Michiko Yamada, Masahiko Kiyama, Yoshihiro Miyamoto, Shizukiyo Ishikawa, Hiroshi Yatsuya

Journal of Epidemiology 27 巻 ( 3 ) 頁： 123 - 129 2017年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Japan Epidemiology Association

Background: Diabetes mellitus is a strong risk factor for cardiovascular disease. However, the age-specific association of diabetes with cardiovascular risk, especially in the elderly, remains unclear in non-Western populations. Methods: A pooled analysis was conducted using 8 cohort studies (mean follow-up period, 10.3 years) in Japan, combining the data from 38,854 individual participants without history of cardiovascular disease. In all, 1867 of the participants had diabetes, defined based on the 1998 World Health Organization criteria. The association between diabetes and the risk of death from cardiovascular disease, coronary heart disease (CHD), and stroke was estimated using a stratified Cox model, accounting for variability of baseline hazard functions among cohorts. Results: During the follow-up, 1376 subjects died of cardiovascular disease (including 268 of coronary heart disease and 621 of stroke). Diabetes was associated with an increased risk of cardiovascular death after multivariable adjustment (hazard ratio [HR] 1.62
95% confidence interval [CI], 1.35-1.94). Similarly, diabetes was a risk factor for CHD (HR 2.13
95% CI, 1.47-3.09) and stroke (HR 1.40
95% CI, 1.05-1.85). In the age-stratified analysis of the risk of cardiovascular death, the relative effects of diabetes were consistent across age groups (p for heterogeneity = 0.18), whereas the excess absolute risks of diabetes were greater in participants in their 70s and 80s than in younger subjects. Conclusions: The management of diabetes is important to reduce the risk of death from cardiovascular disease, not only in midlife but also in late life, in the Japanese population.

DOI： 10.1016/j.je.2016.04.001

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Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study 査読有り

Yamagishi K, Iso H, Yatsuya H, Tanabe N, Date C, Kikuchi S, Yamamoto A, Inaba Y, Tamakoshi A; JACC Study Group.

Am J Clin Nutr 92 巻 ( 4 ) 頁： 759-765 2010年10月

Sex-Specific HDL Cholesterol Changes With Weight Loss and Their Association With Anthropometric Variables: The LIFE Study 査読有り国際共著

Yatsuya H, Jeffery RW, Erickson DJ, Welsh EM, Flood AP, Jaeb MA, Laqua PS, Mitchell NR, Langer SL, Levy RL

Obesity (Silver Spring) Epub 巻 2010年9月

Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study. 査読有り国際共著

Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR; ARIC Study Investigators.

J Epidemiol 20 巻 ( 5 ) 頁： 347-354 2010年9月

Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study. 査読有り国際共著

Yatsuya H, Folsom AR; ARIC Investigators.

Am J Epidemiol 172 巻 ( 5 ) 頁： 600-605 2010年9月

Body mass index and risk of stroke and myocardial infarction in a relatively lean population: meta-analysis of 16 Japanese cohorts using individual data. 査読有り

Yatsuya H, Toyoshima H, Yamagishi K, Tamakoshi K, Taguri M, Harada A, Ohashi Y, Kita Y, Naito Y, Yamada M, Tanabe N, Iso H, Ueshima H; Japan Arteriosclerosis Longitudinal Study (JALS) group.

Circ Cardiovasc Qual Outcomes. 3 巻 ( 5 ) 頁： 498-505 2010年9月

Maintenance-tailored therapy vs. standard behavior therapy for 30-month maintenance of weight loss. 査読有り国際共著

Levy RL, Jeffery RW, Langer SL, Graham DJ, Welsh EM, Flood AP, Jaeb MA, Laqua PS, Finch EA, Hotop AM, Yatsuya H.

Prev Med Epub 巻 2010年9月

Incidence of metabolic syndrome according to combinations of lifestyle factors among middle-aged Japanese male workers. 査読有り

Li Y, Yatsuya H, Iso H, Tamakoshi K, Toyoshima H.

Prev Med 51 巻 ( 2 ) 頁： 118-122 2010年8月

Retinal microvascular abnormalities and risk of lacunar stroke: Atherosclerosis Risk in Communities Study 査読有り国際共著

Yatsuya H, Folsom AR, Wong TY, Klein R, Klein BE, Sharrett AR; ARIC Study Investigators.

Stroke 41 巻 ( 7 ) 頁： 1349-1355 2010年7月

Demographic and cardiovascular risk factors modify association of fasting insulin with incident coronary heart disease and ischemic stroke (from the Atherosclerosis Risk In Communities Study). 査読有り国際共著

Rasmussen-Torvik LJ, Yatsuya H, Selvin E, Alonso A, Folsom AR.

Am J Cardiol 105 巻 ( 10 ) 頁： 1420-1425 2010年5月

Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese. 査読有り

Muramatsu T, Yatsuya H, Toyoshima H, Sasaki S, Li Y, Otsuka R, Wada K, Hotta Y, Mitsuhashi H, Matsushita K, Murohara T, Tamakoshi K.

Prev Med. 50 巻 ( 5-6 ) 頁： 272-276 2010年5月

Race- and Sex-Specific Associations of Obesity Measures With Ischemic Stroke Incidence in the Atherosclerosis Risk in Communities (ARIC) Study 査読有り国際共著

Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J; for the ARIC Study Investigators

Stroke 41 巻 ( 3 ) 頁： 417-425 2010年3月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND AND PURPOSE: Studies have suggested differences in the association between obesity and ischemic stroke in black versus white populations. In this study, we explored ischemic stroke risk in relation to a variety of obesity measures by sex and race. METHODS: Using data from the Atherosclerosis Risk in Communities Study, we obtained information on body mass index, waist circumference, and waist-to-hip ratio from 13 549 black and white participants who were aged 45 to 65 years between 1987 and 1989. All were free of cardiovascular disease and cancer at baseline. Incident strokes over a median follow-up of 16.9 years were ascertained from hospital records. RESULTS: Although crude incidence rates of ischemic stroke varied more than 3-fold by race and sex, the relationship between higher measures of obesity and ischemic stroke risk was positive and linear across all groups. The crude incidence of ischemic stroke was 1.2 per 1000 person-years for white women with the lowest body mass index, ranging up to 8.0 per 1000 person-years for black men with the highest body mass index. Hazard ratios for the highest versus lowest quintile of body mass index, waist circumference, and waist-to-hip ratio ranged from 1.43 to 3.19, indicating increased stroke risk associated with obesity, however it was measured, even after adjustment for potential confounders. Additional adjustment for factors that may mediate the relationship, such as diabetes and hypertension, significantly attenuated the associations, suggesting that these factors may explain much of the stroke risk associated with obesity. CONCLUSIONS: Degree of obesity, defined by body mass index, waist circumference, or waist-to-hip ratio, was a significant risk factor for ischemic stroke regardless of sex or race.

Daytime napping and mortality, with a special reference to cardiovascular disease: the JACC study 査読有り

Tanabe N, Iso H, Seki N, Suzuki H, Yatsuya H, Toyoshima H, Tamakoshi A; for the JACC Study Group

Int J Epidemiol 39 巻 ( 1 ) 頁： 233-243 2010年2月

BMI and all-cause mortality among Japanese older adults: findings from the Japan collaborative cohort study. 査読有り

Tamakoshi A, Yatsuya H, Lin Y, Tamakoshi K, Kondo T, Suzuki S, Yagyu K, Kikuchi S; JACC Study Group

Obesity (Silver Spring) 18 巻 ( 2 ) 頁： 362-369 2010年2月

Vaginal douching in Cambodian women: its prevalence and association with vaginal candidiasis 査読有り国際共著

Heng LS, Yatsuya H, Morita S, Sakamoto J

J Epidemiol 20 巻 ( 1 ) 頁： 70-76 2010年

Changes in C-reactive protein during weight loss and the association with changes in anthropometric variables in men and women: LIFE Study. 査読有り国際共著

Yatsuya H, Jeffery RW, Langer SL, Mitchell N, Flood AP, Welsh EM, Jaeb MA, Laqua PS, Crowell M, Levy RL

Int J Obes (Lond). Epub 巻 2010年

Factors predicting growth of vestibular schwannoma in neurofibromatosis type 2. 査読有り

Ito E, Saito K, Yatsuya H, Nagatani T, Otsuka G

Neurosurg Rev 32 巻 ( 4 ) 頁： 425-433 2009年10月

Changes in activities of dail living, physical fitness, and depressive symptoms after six-month periodic well-rounded exercise programs for older adults living in nursing homes or special nursing facilities 査読有り

Ouyang P, Yatsuya H, Toyoshima H, Otsuka R, Wada K, Matsushita K, Ishikawa M, Lee Y, Hotta Y, Mitsuhashi H, Muramatsu T, Kasuga N, Tamakoshi K

Nagoya J Med Sci 71 巻 ( 3-4 ) 頁： 115-126 2009年9月

Multilevel analyses of effects of variation in body mass index on serum lipid concentrations in middle-aged Japanese men. 査読有り

Kondo T, Kimata A, Yamamoto K, Ueyama S, Ueyama J, Yatsuya H, Tamakoshi K, Hori Y

Nagoya J Med Sci 71 巻 ( 1-2 ) 頁： 19-28 2009年2月

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