研究者詳細 - 八谷　寛

論文 - 八谷　寛

分割表示 371 件中 301 - 320 件目／全件表示 >>

Interleukin-8 gene polymorphism associated with susceptibility to non-cardia gastric carcinoma with microsatellite instability. 査読有り

Shirai K, Ohmiya N, Taguchi A, Mabuchi N, Yatsuya H, Itoh A, Hirooka Y, Niwa Y, Mori N, Goto H.

J Gastroenterol Hepatol 21 巻 ( 7 ) 頁： 1129-1135 2006年

Seasonal variations of acute massive submacular haemorrhage associated with age-related macular degeneration. 査読有り

Iguchi Y, Ito Y, Kikuchi M, Ishikawa K, Oshima H, Yatsuya H, Terasaki H.

Br J Ophthalmol 90 巻 ( 10 ) 頁： 1256-1258 2006年

Factors related to frequency of engaging in outside activities among elderly persons living an independent life at home. 査読有り Open Access

Ishikawa M, Tamakoshi K, Yatsuya H, Suma K, Wada K, Otsuka R, Matsushita K, Zhang H, Murata C, Kondo T, Toyoshima H.

Nagoya J Med Sci 68 巻 ( 3-4 ) 頁： 121-130 2006年

HIV prevalence and factors associated with HIV infection among male injection drug users under 30: a cross-sectional study in Long An, Vietnam. 査読有り国際共著 Open Access

Tran TM, Nguyen HT, Yatsuya H, Hamajima N, Nishimura A, Ito K.

BMC Public Health 10 巻 ( 6 ) 頁： 248 2006年

A positive association between leptin and blood pressure of normal range in Japanese men. 査読有り

Wada K, Yatsuya H, Tamakoshi K, Otsukai R, Fujii C, Matsushita K, Sugiura K, Toyoshima H.

Hypertens Res 29 巻 ( 7 ) 頁： 485-492 2006年

Serum levels of insulin-like growth factor I, II, and binding protein 3, transforming growth factor beta-1, soluble fas ligand and superoxide dismutase activity in stomach cancer cases and their controls in the JACC Study. 査読有り

Yatsuya H, Toyoshima H, Tamakoshi K, Tamakoshi A, Kondo T, Hayakawa N, Sakata K, Kikuchi S, Hoshiyama Y, Fujino Y, Mizoue T, Tokui N, Yoshimura T; JACC Study Group.

Journal of Epidemiology 15 巻 ( S2 ) 頁： S120-S125 2005年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND: The prognosis of stomach cancer with advanced stage remains poor. New biomarkers of the disease that may contribute to establish the potential screening strategy would be of value for the early detection of individuals at high risk of the disease. METHODS: We conducted a prospective, nested case-control analysis among apparently healthy men and women who were followed for up to 8 years in the Japan Collaborative Cohort (JACC) Study, to evaluate serum levels of insulin-like growth factor I, II, and binding protein 3 (IFG-I, IGF-II, and IGFBP-3), transforming growth factorbeta-1 (TGFbeta1), soluble fas (sFas) and superoxide dismutase activity (SOD) in 210 stomach cancer cases diagnosed in the JACC Study in relation to those levels in their 410 controls. RESULTS: Among 6 serum biomarkers tested for case-control differences, only sFas level in female stomach cancer cases was significantly higher than that of controls (2.22 pg/ml vs. 2.04 pg/mL, respectively; P=0.013 by two-way analysis of covariance controlling for matching variable). CONCLUSION: None of the biomarkers consistently predicted future risk of stomach cancer in both men and women in the present analysis. Serum sFas level in women, however, should be studied much more thoroughly whether it provides meaningful refinement of risk stratification, or it elucidate the mechanisms of tumorigenesis in women.

Lack of an association between serum level of transforming growth factor beta -1 and stomach cancer risk in the JACC study. 査読有り

Yatsuya H, Tamakoshi A, Tamakoshi K, Hoshiyama Y, Fujino Y, Tokui N, Mizoue T, Kikuchi S, Sakata K, Hayakawa N, Kondo T, Toyoshima H, Yoshimura T.

Asian Pacific Journal of Cancer Prevention 6 巻 ( 2 ) 頁： 170-176 2005年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Alterations in the serum concentration of transforming growth factor beta-1 (TGFbeta1) have been observed in gastric cancer patients. No study, however, has ever examined the association between the serum TGFbeta1 level and stomach cancer prospectively. We conducted a prospective, nested case-control analysis among apparently healthy men and women who were followed for up to 8 years in the JACC Study to assess whether serum level of total TGFbeta1 is associated with a subsequent risk of stomach cancer. The concentration of serum TGFbeta1 in previously collected blood samples was analyzed by ELISA for 209 individuals in whom a diagnosis of stomach cancer was documented, and for 409 controls matched with them for gender, age and study area. Baseline blood levels of TGFbeta1 were not related to the risk of stomach cancer in either men or women, a finding unchanged even after adjustment for potential confounders. The multivariate-adjusted odds ratio of stomach cancer in men and women was 1.10 (95% CI, 0.82 to 1.48) and 1.09 (95% CI, 0.80 to 1.48), respectively, for each increase of 1 SD in the TGFbeta1 value. In conclusion, serum TGFbeta1 levels were not associated with increased risks of subsequent stomach cancer.

Familial aggregation and coaggregation of history of hypertension and stroke. 査読有り

Kondo T, Toyoshima H, Tsuzuki Y, Hori Y, Yatsuya H, Tamakoshi K, Tamakoshi A, Ohno Y; JACC Study Group.

J Hum Hypertens 19 巻 ( 2 ) 頁： 119-25 2005年

Long-term body weight fluctuation is associated with metabolic syndrome independent of current body mass index among Japanese men. 査読有り Open Access

Zhang H, Tamakoshi K, Yatsuya H, Murata C, Wada K, Otsuka R, Nagasawa N, Ishikawa M, Sugiura K, Matsushita K, Hori Y, Kondo T, Toyoshima H.

Circ J 69 巻 ( 1 ) 頁： 13-8 2005年

Impact of menstrual and reproductive factors on breast cancer risk in Japan: results of the JACC study. 査読有り

Tamakoshi K, Yatsuya H, Wakai K, Suzuki S, Nishio K, Lin Y, Niwa Y, Kondo T, Yamamoto A, Tokudome S, Toyoshima H, Tamakoshi A; JACC Study Group.

Cancer Sci 96 巻 ( 1 ) 頁： 57-62 2005年

Association between serum leptin concentration and white blood cell count in middle-aged Japanese men and women. 査読有り

Mabuchi T, Yatsuya H, Tamakoshi K, Otsuka R, Nagasawa N, Zhang H, Murata C, Wada K, Ishikawa M, Hori Y, Kondo T, Hashimoto S, Toyoshima H.

Diabetes Metab Res Rev 21 巻 ( 5 ) 頁： 441-7 2005年

Cigarette smoking and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort study. 査読有り

Niwa Y, Wakai K, Suzuki S, Tamakoshi K, Lin Y, Yatsuya H, Kondo T, Nishio K, Yamamoto A, Tokudome S, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

J Obstet Gynaecol Res 31 巻 ( 2 ) 頁： 144-51 2005年

Prospective study of alcohol consumption and breast cancer risk in Japanese women. 査読有り

Lin Y, Kikuchi S, Tamakoshi K, Wakai K, Kondo T, Niwa Y, Yatsuya H, Nishio K, Suzuki S, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A.

Int J Cancer 116 巻 ( 5 ) 頁： 779-83 2005年

Validity of self-reported height and weight in a Japanese workplace population. 査読有り

Wada K, Tamakoshi K, Tsunekawa T, Otsuka R, Zhang H, Murata C, Nagasawa N, Matsushita K, Sugiura K, Yatsuya H, Toyoshima H.

Int J Obes Relat Metab Disord 29 巻 ( 9 ) 頁： 1093-9 2005年

Effects of social relationships on mortality among the elderly in a Japanese rural area: an 88-month follow-up study. 査読有り Open Access

Murata C, Takaaki K, Hori Y, Miyao D, Tamakoshi K, Yatsuya H, Sakakibara H, Toyoshima H.

J Epidemiol 15 巻 ( 3 ) 頁： 78-84 2005年

Gender difference of sudden death 招待有り

Tamakoshi K, Toyoshima H, Yatsuya H.

Nippon Rinsho 63 巻 ( 7 ) 頁： 1284-8 2005年

Leptin is associated with an increased female colorectal cancer risk: a nested case-control study in Japan. 査読有り

Tamakoshi K, Toyoshima H, Wakai K, Kojima M, Suzuki K, Watanabe Y, Hayakawa N, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki S, Kawado M, Ozasa K, Ito Y, Tamakoshi A.

Oncology 68 巻 ( 4-6 ) 頁： 454-61 2005年

Green tea and stomach cancer--a short review of prospective studies. 査読有り

Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Yoshimura T; JACC Study Group.

J Epidemiol 15 巻 ( S2 ) 頁： S109-12 2005年

Cigarette smoking and mortality due to stomach cancer: findings from the JACC Study. 査読有り

Fujino Y, Mizoue T, Tokui N, Kikuchi S, Hoshiyama Y, Toyoshima H, Yatsuya H, Sakata K, Tamakoshi A, Ide R, Kubo T, Yoshimura T; JACC Study Group.

J Epidemiol 15 巻 ( S2 ) 頁： S113-S119 2005年

Serum pepsinogen values and Helicobacter pylori status among control subjects of a nested case-control study in the JACC study. 査読有り Open Access

Kikuchi S, Yagyu K, Obata Y, Yingsong L, Yatsuya H, Hoshiyama Y, Kondo T, Sakata K, Mizoue T, Tokui N, Fujino Y, Tamakoshi A, Toyoshima H, Ishibashi T, Hayakawa N, Yoshimura T; JACC Study Group.

J Epidemiol 15 巻 ( S2 ) 頁： S126-S133 2005年

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