研究者詳細 - 佐藤　ちひろ

論文 - 佐藤　ちひろ

分割表示 401 件中 281 - 300 件目／全件表示 >>

Membrane microdomains from early gastrula embryos of medaka, Oryzias latipes are a plat form of E-cadherin and carbohydrate-mediated cell-cell interactions during epiboly 査読有り

Adachi T, Sato, C, Kishi, Y, Totani, K, Murata, T, Usui, T, Kitajima, K

Glycoconjugate J. 26 巻頁： 285-299 2009年

[Regulation of signal transduction by polysialic acid]. 査読有り

Sato C, Kitajima K

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 53 巻 ( 12 Suppl ) 頁： 1577 - 1583 2008年9月

Direct binding of polysialic acid to a brain-derived neurotrophic factor depends on the degree of polymerization 査読有り

Kanato, Y, Kitajima, K., and Sato, C.

Glycobiology 12 巻頁： 1044-1053 2008年

ポリシアル酸構造による細胞シグナルの調節機構招待有り

佐藤ちひろ、北島健

蛋白質核酸酵素 53 巻 ( 1577-1583 ) 2008年

Direct binding of polysialic acid to a brain-derived neurotrophic factor depends on the degree of polymerization 査読有り

Kanato, Y, Kitajima, K, Sato, C

Glycobiology 12 巻頁： 1044-1053 2008年

Glycobiology of polysialic acids on sea urchin gametes Open Access

Miyata Shinji, Sato Chihiro, Kitajima Ken

TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 19 巻 ( 106 ) 頁： 85-98 2007年3月

Identification of an inflammation-inducible serum protein recognized by anti-disialic acid antibodies as carbonic anhydrase II. 査読有り

Yasukawa Z, Sato C, Kitajima K

Journal of biochemistry 141 巻 ( 3 ) 頁： 429 - 41 2007年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Biochemistry

Acute-phase proteins are an important marker of inflammation and sometimes have a role in the general defense response towards tissue injury. In the present study, we identified a 32-kDa protein that was immunoreactive with monoclonal antibody 2-4B (mAb.2-4B), which is specific to di/oligoNeu5Gc structures, and that behaved as an acute-phase protein following stimulation with either turpentine oil or lipopolysaccharides. The 32-kDa protein was identified as carbonic anhydrase II (CA-II), based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analyses of the purified protein. Mouse and human CA-II was immunoreactive and immunoprecipitated with mAb.2-4B, but contained no sialic acid. In addition to mAb.2-4B, the mAb. S2-566 an antibody specific for diNeu5Ac-containing glycans, recognized the CA-II, whereas an anti-oligo/polysialic acid antibody did not. These results indicate that a part of the CA-II protein structure mimics the disialic acid structure recognized by the monoclonal antibodies. This is the first report that CA-II circulates in the serum following inflammation. © 2007 The Japanese Biochemical Society.

DOI： 10.1093/jb/mvm047

Web of Science

Scopus

PubMed

Heterocomplex formation and cell-surface accumulation of hen's serum zona pellucida B1 (ZPB1) with ZPC expressed by a mammalian cell line (COS-7): A possible initiating step of egg-envelope matrix construction Open Access

Okumura Hiroki, Aoki Naohito, Sato Chihiro, Nadano Daita, Matsuda Tsukasa

BIOLOGY OF REPRODUCTION 76 巻 ( 1 ) 頁： 9-18 2007年1月

Heterocomplex formation and cell-surface accumulation of hen's serum zona pellucida B1 (ZPB1)with ZPC expressed by a mammalian cell line (COS-7): a possible initiating step of egg-envelope matrix construction. 査読有り Open Access

Okumura H, Aoki N, Sato C, Nadano D, Matsuda T

Biology of reproduction 76 巻 ( 1 ) 頁： 9 - 18 2007年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Biology of Reproduction

The egg envelope, referred to as zona pellucida (ZP) in mammalian eggs, is a fibrous and noncollagenous extracellular matrix surrounding vertebrate eggs, and composed of three to four homologous glycoproteins with a common ZP domain. In birds, a liver-derived ZP glycoprotein (ZP1/ZPB1) is transported through the bloodstream to ovarian follicles and joins the egg-envelope matrix construction together with the other ZP glycoproteins, such as ZPC and ZPD/ZPX2, both secreted from follicular granulosa cells. We report here that, through its ZP domain, ZPB1 specifically associates with ZPC, which might lead to the construction of egg-envelope matrix. The ZPB1 in laying hen's serum specifically bound to ZPC, but not to ZPX2, separated by SDS-PAGE and blotted on a membrane. Hemagglutinin (HA)-tagged ZPC expressed in a mammalian cell line (COS-7) cells was processed and secreted as a mature-form into the culture medium. From the culture supernatant of ZPC-expressing transfectants cultured in the presence of ZPB1, both ZPB1 and ZPC were recovered as heterocomplexes by immunoprecipitation using either anti-HA or anti-ZPB1 antibody. Interestingly, a monoclonal antibody, 8E1, which immunoprecipitated free ZPB1, did not immunoprecipitate the ZPB1-ZPC heterocomplexes. An 8E1 epitope was mapped on a C-terminal region of the ZP domain in a ZPB1 molecule by identifying an 8E1-positive peptide using mass spectroscopy. Furthermore, by laser scanning confocal microscopy, ZPB1 and ZPC were observed to colocalize on the surface of ZPC-expressing transfectants cultured in the presence of ZPB1, whereas almost no ZPC was detected on the surface of the transfectants cultured in the absence of ZPB1. Taken together, these results suggest that ZPB1 transported into ovarian follicles encounters and associates with ZPC secreted from granulosa cells, resulting in the formation of heterocomplexes around an oocyte. In addition, it appears that such ZPB1-ZPC complexes accumulated on the oocyte surface act as a scaffold for subsequent matrix construction events including ZPX2 association. © 2007 by the Society for the Study of Reproduction, Inc.

DOI： 10.1095/biolreprod.106.056267

Web of Science

Scopus

PubMed

Complex formation of 70-kDa heat shock protein with acidic glycolipids and phospholipids. 査読有り

Harada Y, Sato C, Kitajima K.

Biochem Biophys Res Commun. 353 巻頁： 655-660 2007年

The rainbow trout CMP-sialic acid synthetase utilises a nuclear localization signal different from that identified in the mouse enzyme. 査読有り Open Access

Tiralongo J, Fujita A, Sato C, Kitajima K, Lehmann F, Oschlies M, Gerardy-Schahn R, Munster-Kuhnel AK.

Glycobiology 17 巻頁： 945-954 2007年

Identification of an inflammation-inducible serum protein recognized by anti-disialic acid antibodies as carbonic anhydrase II. 査読有り

Yasukawa, Z., Sato, C., and Kitajima, K.

J Biochem. 141 巻頁： 429-441 2007年

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Acute phase proteins are an important marker of inflammation and sometimes have a role in the general defense response towards tissue injury. In the present study, we identified a 32 kDa protein that was immunoreactive with monoclonal antibody 2-4B (mAb.2-4B), which is specific to di/oligoNeu5Gc structures, and that behaved as an acute phase protein following stimulation with either turpentine oil or lipopolysaccharides. The 32 kDa protein was identified as carbonic anhydrase II (CA-II), based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analyses of the purified protein. Mouse and human CA-II was immunoreactive and immunoprecipitated with mAb.2-4B, but contained no sialic acid. In addition to mAb.2-4B, the mAb. S2-566 an antibody specific for diNeu5Ac-containing glycans, recognized the CA-II, whereas an anti-oligo/polysialic acid antibody did not. These results indicate that a part of the CA-II protein structure mimics the disialic acid structure recognized by the monoclonal antibodies. This is the first report that CA-II circulates in the serum following inflammation.

DOI： 10.1093/jb/mvm047

シアル酸の構造多様性とその生物学的意義. 招待有り

北島　健、郷　慎司、藤田　明子、佐藤ちひろ

細胞工学 26 巻頁： 629-634 2007年

Membrane microdomain formation is crucial in epiboly during gastrulation of medaka. 査読有り

Adachi, T., Sato, C., and Kitajima, K.

Biochem. Biophys. Res. Commun. 355 巻頁： 174-180 2007年

Development of sensitive chemical and immunochemical methods for detecting sulfated sialic acids and their application to glycoconjugates from sea urchin sperm and eggs 査読有り

Yamakawa, N., Sato C., Miyata, S., Maehashi, E., Toriyama, T., Sato, N., Furuhata, K., and Kitajima. K.

Biochimie 89 巻頁： 1396-1408 2007年

Glycobiology of polysialic acids on sea urchin gametes. 招待有り査読有り Open Access

Miyata, S., Sato, C., and Kitajima, K.

Trends Glycosci. Glycotech. 19 巻頁： 83-95 2007年

Hypoxia-enhanced expression of free deaminoneuraminic acid in human cancer cells. 査読有り

Go, S., Sato, C., Yin, J., Kannagi, R., and Kitajima, K.

Biochem. Biophys. Res. Commun. 357 巻頁： 537-542. 2007年

Identification of the nuclear export signals that regulate the intracellular localization of the mouse CMP-sialic acid synthetase. 査読有り

Fujita, A, Sato C, and Kitajima, K.

Biochem. Biophys. Res. Commun. 355 巻頁： 174-180 2007年

The rainbow trout CMP-sialic acid synthetase utilises a nuclear localization signal different from that identified in the mouse enzyme. 査読有り Open Access

Tiralongo J, Fujita A, Sato C, Kitajima K, Lehmann F, Oschlies M, Gerardy-Schahn R, Munster-Kuhnel AK

Glycobiology 17 巻頁： 945-954 2007年

Development of sensitive chemical and immunochemical methods for detecting sulfated sialic acids and their application to glycoconjugates from sea urchin sperm and eggs 査読有り

Yamakawa, N, Sato C, Miyata, S, Maehashi, E, Toriyama, T, Sato, N, Furuhata, K, Kitajima. K

Biochimie 89 巻頁： 1396-1408 2007年

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