Faculty Profiles - NAGANAWA, Shinji

Papers - NAGANAWA, Shinji

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Portal Vein Bleeding after Pancreatectomy: Diagnosis and Stent Graft Repair - A Consecutive Case Series. Reviewed

Kojiro Suzuki, Tomoki Ebata, Tomohiro Komada, Masaya Matsushima, Takashi Mizuno, Tsuyoshi Igami, Gen Sugawara, Yukihiro Yokoyama, Shinji Naganawa, Masato Nagino

Journal of the Pancreas. Vol. 18 ( 3 ) page： 241-246 2017.5

Improved HYDROPS: Imaging of Endolymphatic Hydrops after Intravenous Administration of Gadolinium. Reviewed

Shinji Naganawa, Hisashi Kawai, Toshiaki Taoka, Michihiko Sone,

Magn Reson Med Sci. Vol. 16 ( 4 ) page： 357-361 2017.5

Structural MRI correlates of amyotrophic lateral sclerosis progression. Reviewed

Joe Senda, Naoki Atsuta, Hirohisa Watanabe, Epifanio Bagarinao, Kazunori Imai, Daichi Yokoi, Yuichi Riku, Michihito Masuda, Ryoichi Nakamura, Hazuki Watanabe, Mizuki Ito, Masahisa Katsuno, Shinji Naganawa, Gen Sobue

J Neurol Neurosurg Psychiatry. Vol. 88 ( 11 ) page： 901-907 2017.5

Clinical outcome of definitive radiation therapy for superficial esophageal cancer. Reviewed

Yutaro Koide, Takeshi Kodaira, Hiroyuki Tachibana, Natsuo Tomita, Chiyoko Makita, Makoto Itoh, Tetsuya Abe, Kei Muro, Masahiro Tajika, Yasumasa Niwa, Yoshiyuki Itoh, Shinji Naganawa

Jpn J Clin Oncol. Vol. 47 ( 5 ) page： 393-400 2017.5

COPD Assessment Test for measurement of health status in patients with idiopathic pulmonary fibrosis: A cross-sectional study Reviewed

Toshiaki Matsuda, Hiroyuki Taniguchi, Masahiko Ando, Yasuhiro Kondoh, Tomoki Kimura, Kensuke Kataoka, Koji Sakamoto, Atsushi Suzuki, Taiki Furukawa, Yoshinori Hasegawa

RESPIROLOGY Vol. 22 ( 4 ) page： 721 - 727 2017.5

Language：English Publishing type：Research paper (scientific journal) Publisher：WILEY

Background and objectiveThe COPD Assessment Test (CAT) has been reported to have potential utility for measuring health status of idiopathic pulmonary fibrosis (IPF). Although the CAT has been developed for the assessment of COPD patients, it has not been fully evaluated exclusively in IPF. This study was designed to evaluate the validity of the CAT in IPF.
MethodsThe clinical data for 106 consecutive subjects with newly diagnosed IPF who completed pulmonary function tests, partial pressure of oxygen in arterial blood (PaO2 ) at rest, 6-min walk test (6MWT), CAT, St George's Respiratory Questionnaire (SGRQ), modified Medical Research Council (mMRC) dyspnoea grade and Hospital Anxiety and Depression Scale (HADS), were analysed. We assessed the validity of the CAT in comparison with the SGRQ.
ResultsThe present subjects showed mild to moderate restrictive impairment on spirometry. Mean CAT score and total SGRQ were 12.88.0 and 30.817.7, respectively. The concurrent validity of the CAT score in comparison with the SGRQ total score was significant (r=0.72, P<0.001). Internal consistency (Cronbach's =0.869) and repeatability over 3months (intraclass correlation coefficient=0.742) of the CAT were also significant. Single regression analysis showed that the CAT had significant construct validity. In multiple regression analysis, mMRC, PaO2 at rest, minimum SpO(2) during 6MWT and anxiety of HADS were independent predictors for the CAT.
ConclusionsThe CAT is a valid health status measurement in IPF patients. Multiple regression analysis showed that the CAT was significantly correlated with dyspnoea severity, oxygenation impairment and anxiety.
The validity of the COPD Assessment Test (CAT) was evaluated exclusively in idiopathic pulmonary fibrosis (IPF) patients in comparison with the St George's Respiratory Questionnaire (SGRQ). The CAT had a significant correlation with SGRQ and was independently predicted by dyspnoea severity, oxygenation impairment and anxiety.

DOI： 10.1111/resp.12936

Web of Science

PubMed

Altered expression of ganglioside GM3 molecular species and a potential regulatory role during myoblast differentiation

Go Shinji, Go Shiori, Veillon Lucas, Ciampa Maria Grazia, Mauri Laura, Sato Chihiro, Kitajima Ken, Prinetti Alessandro, Sonnino Sandro, Inokuchi Jin-ichi

JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 292 ( 17 ) page： 7040 - 7051 2017.4

CSF Pulsation Artifacts on ADC Maps Obtained with Readout-segmented EPI.

Toshio Ohashi, Shinji Naganawa, Mai Kanou, Mitsuru Ikeda

Magn Reson Med Sci. Vol. 16 ( 2 ) page： 123-128 2017.4

Evaluation of glymphatic system activity with the diffusion MR technique: diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Alzheimer's disease cases. Reviewed

Toshiaki Taoka, Yoshitaka Masutani, Hisashi Kawai, Toshiki Nakane, Kiwamu Matsuoka, Fumihiko Yasuno, Toshifumi Kishimoto, Shinji Naganawa

Jpn. J Radiol. ( 35 ) page： 172-178 2017.4

Lack of Contrast Enhancement in a Giant Perivascular Space of the Basal Ganglion on Delayed FLAIR Images: Implications for the Glymphatic System. Reviewed

Shinji Naganawa, Toshiki Nakane, Hisashi Kawai, Toshiaki Taoka

Magn Reson Med Sci. Vol. 16 ( 2 ) page： 89-90 2017.4

Magnetic resonance imaging evaluation of endolymphatic hydrops andpost-operative findings in cases with otosclerosis.

Michihiko Sone, Tadao Yoshida, Satofumi Sugimoto, Kyoko Morimoto, Yuriko Okazaki, Masaaki Teranishi, Shinji Naganawa, Tsutomu Nakashima

Acta Otolaryngol. Vol. 137 ( 3 ) page： 242-245 2017.3

Do gadolinium-based contrast agents affect the 18F-FDG PET/CT uptake in the dentate nucleus and the globus pallidus? Reviewed

Shinji Naganawa

J Nucl Med Technol. 2017.3

Modulation of immunological activity on macrophages induced by diazinon Reviewed

Nanako Ogasawara, Miyoko Matsushima, Nami Kawamura, Kazuko Atsumi, Takehiro Yamaguchi, Haruka Ochi, Yuto Kusatsugu, Sayaka Oyabu, Naozumi Hashimoto, Yoshinori Hasegawa, Jun Ueyama, Tsutomu Kawabe

TOXICOLOGY Vol. 379 page： 22 - 30 2017.3

Language：English Publishing type：Research paper (scientific journal) Publisher：ELSEVIER IRELAND LTD

Diazinon is an organophosphorus (OP) insecticide and is widely used not only in agriculture but also homes and garden in Japan. Diazinon has been reported to increase TNF-alpha production in rat serum and brain, suggesting that it can modify the proinflammatory response. In this study, we investigated the effects of diazinon on macrophage functions, such as cytokine production, reactive oxygen species (ROS) generation, cyclooxygenase (COX)-2 and inducible nitric oxide synthase (iNOS) expressions, cell-surface molecule expressions, and phagocytosis in RAW264.7 cells. In RAW264.7 cells, diazinon induced the production of TNF-alpha and IL-6. Diazinon induced ROS generation and the expressions of COX-2, iNOS, and cell-surface molecules CD40, CD86, and MI-IC class II, but reduced phagocytic activity in RAW264.7 cells. ERIC and p38, but not JNK and p65 were involved in diazinon-induced IL-6 expression in RAW264.7 cells. We also examined these proinflammatory responses in bone marrow-derived macrophages (BMDM) and bronchoalveolar lavage fluid (BALF) cells. These results suggested that diazinon can activate macrophages and enhance inflammatory responses. (C) 2017 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.tox.2017.01.014

Web of Science

Scopus

Other Link： http://orcid.org/0000-0003-0660-2726

Emerging neuroradiological topics in journals from related societies. Reviewed

Yukunori Korogi, Shinji Naganawa

Jpn. J Radiol. Vol. 35 ( 1 ) page： 1-2 2017.2

Postoperative chemoradiation therapy using high dose cisplatin and fluorouracil for high- and intermediate-risk uterine cervical cancer. Reviewed

Rise Miyauchi, Yoshiyuki Itoh, Mariko Kawamura, Akihiro Hirakawa, Kiyosumi Shibata, Hiroaki Kajiyama, Rie Nakahara, Seiji Kubota, Junji Ito, Tohru Okada, Fumitaka Kikkawa, Shinji Naganawa

Nagoya J Med Sci. Vol. 79 ( 2 ) page： 211-220 2017.2

Imaging of the endolymphatic space in patients with Ménière's disease. Reviewed

Tadao Yoshida, Satofumi Sugimoto, Masaaki Teranishi, Hironao Otake, Masahiro Yamazaki, Shinji Naganawa, Tsutomu Nakashima, Michihiko Sone

Auris Nasus Larynx. ( 17 ) page： 30142-6 2017.2

Dual Energy CTによる小型肺癌の造影評価

島本宏矩, 岩野信吾, 馬越弘泰, 伊藤倫太郎, 長縄慎二

Japanese Journal of Radiology Vol. 35 ( Suppl. ) page： 34 - 34 2017.2

FDG-PETによる非小細胞肺癌の予後予測因子の検討 SUVmaxと体積を考慮した指標の比較

伊藤信嗣, 岩野信吾, 伊藤倫太郎, 長縄慎二, 加藤克彦

核医学 Vol. 54 ( 1 ) page： 565 - 565 2017.2

ドパミントランスポータシンチグラフィにおける解析ソフトの有用性に関する研究

松澤伸一郎, 加藤克彦, 国本啓太, 本田将之, 椋本竜斗, 小田川哲郎, 阿部真治, 藤田尚利, 櫻木庸博, 伊藤信嗣, 伊藤倫太郎, 岩野信吾, 長縄慎二

核医学 Vol. 54 ( 1 ) page： 663 - 663 2017.2

胸壁並行断面CTを用いた間質性肺炎の定量的評価

馬越弘泰, 岩野信吾, 伊藤倫太郎, 長縄慎二

Japanese Journal of Radiology Vol. 35 ( Suppl. ) page： 34 - 34 2017.2

Structure of the Medullary Veins of the Cerebral Hemisphere and Related Disorders. Reviewed

Toshiaki Taoka, Akio Fukuisumi, Toshiteru Miyasaka, Hisashi Kawai, Toshiki Nakane, Kimihiko Kichikawa, Shinji Naganawa

Radiographics. Vol. 37 ( 1 ) page： 281-297 2017.1

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Papers - NAGANAWA, Shinji