Faculty Profiles - YATSUYA Hiroshi

Papers - YATSUYA Hiroshi

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Association between serum leptin concentration and white blood cell count in middle-aged Japanese men and women. Reviewed

Mabuchi T, Yatsuya H, Tamakoshi K, Otsuka R, Nagasawa N, Zhang H, Murata C, Wada K, Ishikawa M, Hori Y, Kondo T, Hashimoto S, Toyoshima H.

Diabetes Metab Res Rev Vol. 21 ( 5 ) page： 441-7 2005

Cigarette smoking and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort study. Reviewed

Niwa Y, Wakai K, Suzuki S, Tamakoshi K, Lin Y, Yatsuya H, Kondo T, Nishio K, Yamamoto A, Tokudome S, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

J Obstet Gynaecol Res Vol. 31 ( 2 ) page： 144-51 2005

Prospective study of alcohol consumption and breast cancer risk in Japanese women. Reviewed

Lin Y, Kikuchi S, Tamakoshi K, Wakai K, Kondo T, Niwa Y, Yatsuya H, Nishio K, Suzuki S, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A.

Int J Cancer Vol. 116 ( 5 ) page： 779-83 2005

Validity of self-reported height and weight in a Japanese workplace population. Reviewed

Wada K, Tamakoshi K, Tsunekawa T, Otsuka R, Zhang H, Murata C, Nagasawa N, Matsushita K, Sugiura K, Yatsuya H, Toyoshima H.

Int J Obes Relat Metab Disord Vol. 29 ( 9 ) page： 1093-9 2005

Effects of social relationships on mortality among the elderly in a Japanese rural area: an 88-month follow-up study. Reviewed Open Access

Murata C, Takaaki K, Hori Y, Miyao D, Tamakoshi K, Yatsuya H, Sakakibara H, Toyoshima H.

J Epidemiol Vol. 15 ( 3 ) page： 78-84 2005

Gender difference of sudden death Invited

Tamakoshi K, Toyoshima H, Yatsuya H.

Nippon Rinsho Vol. 63 ( 7 ) page： 1284-8 2005

Leptin is associated with an increased female colorectal cancer risk: a nested case-control study in Japan. Reviewed

Tamakoshi K, Toyoshima H, Wakai K, Kojima M, Suzuki K, Watanabe Y, Hayakawa N, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki S, Kawado M, Ozasa K, Ito Y, Tamakoshi A.

Oncology Vol. 68 ( 4-6 ) page： 454-61 2005

Green tea and stomach cancer--a short review of prospective studies. Reviewed

Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Yoshimura T; JACC Study Group.

J Epidemiol Vol. 15 ( S2 ) page： S109-12 2005

Cigarette smoking and mortality due to stomach cancer: findings from the JACC Study. Reviewed

Fujino Y, Mizoue T, Tokui N, Kikuchi S, Hoshiyama Y, Toyoshima H, Yatsuya H, Sakata K, Tamakoshi A, Ide R, Kubo T, Yoshimura T; JACC Study Group.

J Epidemiol Vol. 15 ( S2 ) page： S113-S119 2005

Relationship between body mass index and the risk of ovarian cancer in the Japanese population: findings from the Japanese Collaborate Cohort (JACC) study. Reviewed

Niwa Y, Yatsuya H, Tamakoshi K, Nishio K, Kondo T, Lin Y, Suzuki S, Wakai K, Tokudome S, Yamamoto A, Hamajima N, Toyoshima H, Tamakoshi A; JACC Study Group.

J Obstet Gynaecol Res Vol. 31 ( 5 ) page： 452-458 2005

Dietary intakes of fat and fatty acids and risk of breast cancer: a prospective study in Japan. Reviewed

Wakai K, Tamakoshi K, Date C, Fukui M, Suzuki S, Lin Y, Niwa Y, Nishio K, Yatsuya H, Kondo T, Tokudome S, Yamamoto A, Toyoshima H, Tamakoshi A; JACC Study Group.

Cancer Sci Vol. 96 ( 9 ) page： 590-599 2005

Association of white blood cell count and clustered components of metabolic syndrome in Japanese men. Reviewed Open Access

Nagasawa N, Tamakoshi K, Yatsuya H, Hori Y, Ishikawa M, Murata C, Zhang H, Wada K, Otsuka R, Mabuchi T, Kondo T, Toyoshima H.

Circ J Vol. 68 ( 10 ) page： 892-7 2004

玉腰浩司,八谷寛,豊嶋英明. Invited

Vol. 208 page： 229-230 2004

肥満を伴った高脂血症患者に対する運動療法の効果に関する研究　行動医学的アプローチを用いた運動習慣の定着による動脈硬化促進要因の改善に関する研究 Invited

下光輝一, 井上茂, 小田切優子, 高波嘉一, 豊嶋英明, 八谷寛, 玉腰浩司, 近藤高明, 井口ちよ

医科学応用研究財団研究報告 Vol. 21 page： 215-223 2004

日本人男性における血清レプチン濃度と5年間追跡後の体重変化. Invited

八谷寛, 玉腰浩司, 大塚礼, 間淵智子, 和田恵子, 張恵明, 村田千代栄, 石川美由紀, 近藤高明, 豊嶋英明.

健康医科学研究助成論文集 Vol. 19 page： 110-117 2004

肥満者における心血管疾患発症の過剰リスクを説明する新しい軸－血清レプチン値と白血球数の関連－ Invited

八谷寛, 淵智子, 大塚礼, 和田恵子, 長澤伸江, 張恵明, 村田千代栄, 石川美由紀, 堀容子, 近藤高明, 玉腰浩司, 豊嶋英明.

健康管理事業団研究助成論文集 Vol. 10 page： 19-25 2004

Individual and joint impact of family history and Helicobacter pylori infection on the risk of stomach cancer: a nested case-control study. Reviewed

Yatsuya H, Toyoshima H, Tamakoshi A, Kikuchi S, Tamakoshi K, Kondo T, Mizoue T, Tokui N, Hoshiyama Y, Sakata K, Hayakawa N, Yoshimura T; Japan Collaborative Cohort Study Group.

British Journal of Cancer Vol. 91 ( 5 ) page： 929-934 2004

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

We used 202 cases of stomach cancer and 394 controls nested within the Japan Collaborative Cohort Study For Evaluation of Cancer Risk (JACC study) to investigate whether family history has an independent effect on the risk of stomach cancer after controlling for the Helicobacter pylori infection. A positive history of stomach cancer in one or more first-degree relatives was associated with an increased risk of the disease in women, but not in men after controlling for H. pylori infection and other confounding variables. Women with both a family history and H. pylori infection were associated with more than five-fold increased risk of the disease (OR 5.10, 95% CI 1.58-16.5) compared to those without these factors. These results suggest the existence of inherited susceptibility to the disease in women, and that measurements of H. pylori infection together with the family history allow meaningful evaluation of risk beyond that provided by either factor alone.

Serum phospholipid transfer protein mass as a possible protective factor for coronary heart diseases. Reviewed Open Access

Yatsuya H, Tamakoshi K, Hattori H, Otsuka R, Wada K, Zhang H, Mabuchi T, Ishikawa M, Murata C, Yoshida T, Kondo T, Toyoshima H.

Circulation Journal Vol. 68 ( 1 ) page： 11-16 2004

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Phospholipid transfer protein (PLTP) can generate pre-beta high-density lipoprotein (HDL), an efficient acceptor of peripheral cholesterol, by mediating a process called HDL conversion. The transfer of phospholipids to immature HDL is also essential in maintaining reverse cholesterol transport. The phospholipid transfer activity of PLTP has been associated with various patho-physiological conditions; however, little information is available concerning the relationship between PLTP mass and disease. METHODS AND RESULTS: Using a sandwich enzyme-linked immunosorbent assay, PLTP concentration was measured and related to the risk of developing cardiovascular disease in a worksite-based cohort of Japanese men (n=2,567). Multiple linear regression analysis showed significant associations between PLTP and HDL cholesterol, triglycerides, low-density lipoprotein cholesterol, and body mass index (standardized beta=0.395, -0.191, -0.064, and -0.064, respectively; R(2)=0.31). During the follow-up period, there were 10 cases of coronary heart disease (CHD) and 7 of stroke. The multivariate adjusted relative risk of CHD was 0.46 (95% confidence interval, 0.20-1.07) for an increase of 1 standard deviation in the PLTP value (p=0.071). PLTP concentration was not related to the risk of stroke. CONCLUSIONS: The results of this prospective study indicate that the serum PLTP concentration would serve as a predictor of CHD, independent of HDL cholesterol, triglycerides and other established risk factors.

DOI： 10.1253/circj.68.11

Open Access

A nested case-control study of stomach cancer in relation to green tea consumption in Japan. Reviewed

Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Ohno Y, Yoshimura T; Japan Collaborative Cohort Study Group.

Br J Cancer Vol. 90 ( 1 ) page： 135-8 2004

A prospective study of body size and colon cancer mortality in Japan: The JACC Study. Reviewed

Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Ito Y, Tamakoshi A; JACC Study Group.

Int J Obes Relat Metab Disord Vol. 28 ( 4 ) page： 551-8 2004

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Papers - YATSUYA Hiroshi