Faculty Profiles - YATSUYA Hiroshi

Papers - YATSUYA Hiroshi

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Risk Factor of Cardiovascular Disease Among Older Individuals Reviewed International journal

Hiroshi Yatsuya, Masaaki Matsunaga, Yuanying Li, Atsuhiko Ota

JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS Vol. 24 ( 3 ) page： 258 - 261 2017

Age-specific impact of diabetes mellitus on the risk of cardiovascular mortality: An overview from the evidence for Cardiovascular Prevention from Observational Cohorts in the Japan Research Group (EPOCH-JAPAN) Reviewed

Yoichiro Hirakawa, the Evidence for Cardiovascular Prevention From Observational Cohorts in Japan Research Group (EPOCH-JAPAN), Toshiharu Ninomiya, Yutaka Kiyohara, Yoshitaka Murakami, Shigeyuki Saitoh, Hideaki Nakagawa, Akira Okayama, Akiko Tamakoshi, Kiyomi Sakata, Katsuyuki Miura, Hirotsugu Ueshima, Tomonori Okamura, Yutaka Imai, Takayoshi Ohkubo, Fujiko Irie, Hiroyasu Iso, Akihiko Kitamura, Takeo Nakayama, Toshimi Sairenchi, Ichiro Tsuji, Michiko Yamada, Masahiko Kiyama, Yoshihiro Miyamoto, Shizukiyo Ishikawa, Hiroshi Yatsuya

Journal of Epidemiology Vol. 27 ( 3 ) page： 123 - 129 2017

Language：English Publishing type：Research paper (scientific journal) Publisher：Japan Epidemiology Association

Background: Diabetes mellitus is a strong risk factor for cardiovascular disease. However, the age-specific association of diabetes with cardiovascular risk, especially in the elderly, remains unclear in non-Western populations. Methods: A pooled analysis was conducted using 8 cohort studies (mean follow-up period, 10.3 years) in Japan, combining the data from 38,854 individual participants without history of cardiovascular disease. In all, 1867 of the participants had diabetes, defined based on the 1998 World Health Organization criteria. The association between diabetes and the risk of death from cardiovascular disease, coronary heart disease (CHD), and stroke was estimated using a stratified Cox model, accounting for variability of baseline hazard functions among cohorts. Results: During the follow-up, 1376 subjects died of cardiovascular disease (including 268 of coronary heart disease and 621 of stroke). Diabetes was associated with an increased risk of cardiovascular death after multivariable adjustment (hazard ratio [HR] 1.62
95% confidence interval [CI], 1.35-1.94). Similarly, diabetes was a risk factor for CHD (HR 2.13
95% CI, 1.47-3.09) and stroke (HR 1.40
95% CI, 1.05-1.85). In the age-stratified analysis of the risk of cardiovascular death, the relative effects of diabetes were consistent across age groups (p for heterogeneity = 0.18), whereas the excess absolute risks of diabetes were greater in participants in their 70s and 80s than in younger subjects. Conclusions: The management of diabetes is important to reduce the risk of death from cardiovascular disease, not only in midlife but also in late life, in the Japanese population.

DOI： 10.1016/j.je.2016.04.001

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Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study Reviewed

Yamagishi K, Iso H, Yatsuya H, Tanabe N, Date C, Kikuchi S, Yamamoto A, Inaba Y, Tamakoshi A; JACC Study Group.

Am J Clin Nutr Vol. 92 ( 4 ) page： 759-765 2010.10

Sex-Specific HDL Cholesterol Changes With Weight Loss and Their Association With Anthropometric Variables: The LIFE Study Reviewed International coauthorship

Yatsuya H, Jeffery RW, Erickson DJ, Welsh EM, Flood AP, Jaeb MA, Laqua PS, Mitchell NR, Langer SL, Levy RL

Obesity (Silver Spring) Vol. Epub 2010.9

Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study. Reviewed International coauthorship

Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR; ARIC Study Investigators.

J Epidemiol Vol. 20 ( 5 ) page： 347-354 2010.9

Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study. Reviewed International coauthorship

Yatsuya H, Folsom AR; ARIC Investigators.

Am J Epidemiol Vol. 172 ( 5 ) page： 600-605 2010.9

Body mass index and risk of stroke and myocardial infarction in a relatively lean population: meta-analysis of 16 Japanese cohorts using individual data. Reviewed

Yatsuya H, Toyoshima H, Yamagishi K, Tamakoshi K, Taguri M, Harada A, Ohashi Y, Kita Y, Naito Y, Yamada M, Tanabe N, Iso H, Ueshima H; Japan Arteriosclerosis Longitudinal Study (JALS) group.

Circ Cardiovasc Qual Outcomes. Vol. 3 ( 5 ) page： 498-505 2010.9

Maintenance-tailored therapy vs. standard behavior therapy for 30-month maintenance of weight loss. Reviewed International coauthorship

Levy RL, Jeffery RW, Langer SL, Graham DJ, Welsh EM, Flood AP, Jaeb MA, Laqua PS, Finch EA, Hotop AM, Yatsuya H.

Prev Med Vol. Epub 2010.9

Incidence of metabolic syndrome according to combinations of lifestyle factors among middle-aged Japanese male workers. Reviewed

Li Y, Yatsuya H, Iso H, Tamakoshi K, Toyoshima H.

Prev Med Vol. 51 ( 2 ) page： 118-122 2010.8

Retinal microvascular abnormalities and risk of lacunar stroke: Atherosclerosis Risk in Communities Study Reviewed International coauthorship

Yatsuya H, Folsom AR, Wong TY, Klein R, Klein BE, Sharrett AR; ARIC Study Investigators.

Stroke Vol. 41 ( 7 ) page： 1349-1355 2010.7

Demographic and cardiovascular risk factors modify association of fasting insulin with incident coronary heart disease and ischemic stroke (from the Atherosclerosis Risk In Communities Study). Reviewed International coauthorship

Rasmussen-Torvik LJ, Yatsuya H, Selvin E, Alonso A, Folsom AR.

Am J Cardiol Vol. 105 ( 10 ) page： 1420-1425 2010.5

Higher dietary intake of alpha-linolenic acid is associated with lower insulin resistance in middle-aged Japanese. Reviewed

Muramatsu T, Yatsuya H, Toyoshima H, Sasaki S, Li Y, Otsuka R, Wada K, Hotta Y, Mitsuhashi H, Matsushita K, Murohara T, Tamakoshi K.

Prev Med. Vol. 50 ( 5-6 ) page： 272-276 2010.5

Race- and Sex-Specific Associations of Obesity Measures With Ischemic Stroke Incidence in the Atherosclerosis Risk in Communities (ARIC) Study Reviewed International coauthorship

Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J; for the ARIC Study Investigators

Stroke Vol. 41 ( 3 ) page： 417-425 2010.3

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

BACKGROUND AND PURPOSE: Studies have suggested differences in the association between obesity and ischemic stroke in black versus white populations. In this study, we explored ischemic stroke risk in relation to a variety of obesity measures by sex and race. METHODS: Using data from the Atherosclerosis Risk in Communities Study, we obtained information on body mass index, waist circumference, and waist-to-hip ratio from 13 549 black and white participants who were aged 45 to 65 years between 1987 and 1989. All were free of cardiovascular disease and cancer at baseline. Incident strokes over a median follow-up of 16.9 years were ascertained from hospital records. RESULTS: Although crude incidence rates of ischemic stroke varied more than 3-fold by race and sex, the relationship between higher measures of obesity and ischemic stroke risk was positive and linear across all groups. The crude incidence of ischemic stroke was 1.2 per 1000 person-years for white women with the lowest body mass index, ranging up to 8.0 per 1000 person-years for black men with the highest body mass index. Hazard ratios for the highest versus lowest quintile of body mass index, waist circumference, and waist-to-hip ratio ranged from 1.43 to 3.19, indicating increased stroke risk associated with obesity, however it was measured, even after adjustment for potential confounders. Additional adjustment for factors that may mediate the relationship, such as diabetes and hypertension, significantly attenuated the associations, suggesting that these factors may explain much of the stroke risk associated with obesity. CONCLUSIONS: Degree of obesity, defined by body mass index, waist circumference, or waist-to-hip ratio, was a significant risk factor for ischemic stroke regardless of sex or race.

Daytime napping and mortality, with a special reference to cardiovascular disease: the JACC study Reviewed

Tanabe N, Iso H, Seki N, Suzuki H, Yatsuya H, Toyoshima H, Tamakoshi A; for the JACC Study Group

Int J Epidemiol Vol. 39 ( 1 ) page： 233-243 2010.2

BMI and all-cause mortality among Japanese older adults: findings from the Japan collaborative cohort study. Reviewed

Tamakoshi A, Yatsuya H, Lin Y, Tamakoshi K, Kondo T, Suzuki S, Yagyu K, Kikuchi S; JACC Study Group

Obesity (Silver Spring) Vol. 18 ( 2 ) page： 362-369 2010.2

Vaginal douching in Cambodian women: its prevalence and association with vaginal candidiasis Reviewed International coauthorship

Heng LS, Yatsuya H, Morita S, Sakamoto J

J Epidemiol Vol. 20 ( 1 ) page： 70-76 2010

Changes in C-reactive protein during weight loss and the association with changes in anthropometric variables in men and women: LIFE Study. Reviewed International coauthorship

Yatsuya H, Jeffery RW, Langer SL, Mitchell N, Flood AP, Welsh EM, Jaeb MA, Laqua PS, Crowell M, Levy RL

Int J Obes (Lond). Vol. Epub 2010

Factors predicting growth of vestibular schwannoma in neurofibromatosis type 2. Reviewed

Ito E, Saito K, Yatsuya H, Nagatani T, Otsuka G

Neurosurg Rev Vol. 32 ( 4 ) page： 425-433 2009.10

Changes in activities of dail living, physical fitness, and depressive symptoms after six-month periodic well-rounded exercise programs for older adults living in nursing homes or special nursing facilities Reviewed

Ouyang P, Yatsuya H, Toyoshima H, Otsuka R, Wada K, Matsushita K, Ishikawa M, Lee Y, Hotta Y, Mitsuhashi H, Muramatsu T, Kasuga N, Tamakoshi K

Nagoya J Med Sci Vol. 71 ( 3-4 ) page： 115-126 2009.9

Multilevel analyses of effects of variation in body mass index on serum lipid concentrations in middle-aged Japanese men. Reviewed

Kondo T, Kimata A, Yamamoto K, Ueyama S, Ueyama J, Yatsuya H, Tamakoshi K, Hori Y

Nagoya J Med Sci Vol. 71 ( 1-2 ) page： 19-28 2009.2

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Papers - YATSUYA Hiroshi