研究者詳細 - 大平　英樹

論文 - 大平　英樹

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Psychological and physiological responses accompanying positive emotions elicited on seeing favorite persons

Matsunaga M., Yamauchi T., Nogimori T., Konagaya T., Ohira H.

Journal of Positive Psychology 3 巻 ( 3 ) 頁： 192 - 201 2008年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Positive Psychology

Positive emotions are evoked on seeing one's favorite person. To investigate the psychological and physiological responses accompanying these positive emotions, we simultaneously recorded various parameters such as the mood state, heart rate, skin conductance level (SCL), serum levels of catecholamines, and proportions of T cells and natural killer (NK) cells among the lymphocytes while participants viewed films featuring their favorite persons. The participants reported that they felt better and invigorated; in addition, SCL and proportion of NK cells in peripheral blood increased significantly, and these physiological changes were positively correlated. These results suggest that positive emotions elicited on seeing a favorite person may lead to psychological and physiological activation and, more importantly, may promote health.

DOI： 10.1080/17439760801999560

Scopus

*Imaging brain and immune association accompanying cognitive appraisal of an acute stressor. 査読有り

Ohira, H., Isowa, T., Nomura, M., Ichikawa, N., Kimura, K., Miyakoshi, M., Iidaka, T., Fukuyama, S., Nakajima, T., Yamada, J.

Neuroimage 22 巻 ( 3 ) 頁： 408-417 2008年3月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

Activities of brain, cardiovascular, endocrine, and immune systems were measured simultaneously and their functional association was examined during an acute stress task where controllability of the stressor was manipulated experimentally. Results revealed that neural network in the orbitofrontal and medial prefrontal cortices is involved in evaluation of controllability and top down modulation over peripheral physiological responses.

Associations among central nervous, endocrine, and immune activities when positive emotions are elicited by looking at a favorite person.

Matsunaga M, Isowa T, Kimura K, Miyakoshi M, Kanayama N, Murakami H, Sato S, Konagaya T, Nogimori T, Fukuyama S, Shinoda J, Yamada J, Ohira H

Brain, behavior, and immunity 22 巻 ( 3 ) 頁： 408 - 17 2008年3月

Associations among central nervous, endocrine, and immune activities when positive emotions are elicited by looking at a favorite person

Matsunaga Masahiro, Isowa Tokiko, Kimura Kenta, Miyakoshi Makoto, Kanayama Noriaki, Murakami Hiroki, Sato Sayaka, Konagaya Toshihiro, Nogimori Tsuyoshi, Fukuyama Seisuke, Shinoda Jun, Yamada Jitsuhiro, Ohira Hideki

BRAIN BEHAVIOR AND IMMUNITY 22 巻 ( 3 ) 頁： 408 - 417 2008年3月

Associations among central nervous, endocrine, and immune activities when positive emotions are elicited by looking at a favorite person

Matsunaga M., Isowa T., Kimura K., Miyakoshi M., Kanayama N., Murakami H., Sato S., Konagaya T., Nogimori T., Fukuyama S., Shinoda J., Yamada J., Ohira H.

Brain, Behavior, and Immunity 22 巻 ( 3 ) 頁： 408 - 417 2008年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Brain, Behavior, and Immunity

Recent studies on psychoneuroimmunology have indicated that positive psychological events are related to immune functions; however, limited information is available regarding associations among the central nervous, endocrine, and immune systems when positive emotions are elicited. In the present study, we demonstrated associations among these systems by simultaneously recording brain, endocrine, and immune activities when positive emotions were evoked in participants as they watched films featuring their favorite persons. Interestingly, the activity of peripheral circulating natural killer cells and the peripheral dopamine level were elevated while participants experienced positive emotions, and these values were positively correlated. The following brain regions were significantly activated in the positive condition relative to the control condition: medial prefrontal cortex, thalamus, hypothalamus, subcallosal gyrus, posterior cingulate cortex, superior temporal gyrus, and cerebellum. Further, covariate analyses indicated that these brain regions were temporally associated with endocrine and immune activities. These results suggest that while an individual experiences positive emotions, the central nervous, endocrine, and immune systems may be interrelated and attraction for favorite persons may be associated with the activation of the innate immune function via the dopaminergic system. © 2007 Elsevier Inc. All rights reserved.

DOI： 10.1016/j.bbi.2007.09.008

Scopus

Associations among central nervous, endocrine, and immune activities when positive emotions are elicited by looking at a favorite person 査読有り

Masahiro Matsunaga, Tokiko Isowa, Kenta Kimura, Makoto Miyakoshi, Noriaki Kanayama, Hiroki Murakami, Sayaka Sato, Toshihiro Konagaya, Tsuyoshi Nogimori, Seisuke Fukuyama, Jun Shinoda, Jitsuhiro Yamada, Hideki Ohira

BRAIN BEHAVIOR AND IMMUNITY 22 巻 ( 3 ) 頁： 408 - 417 2008年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ACADEMIC PRESS INC ELSEVIER SCIENCE

DOI： 10.1016/j.bbi.2007.09.008

Web of Science

Imaging brain and immune association accompanying cognitive appraisal of an acute stressor 査読有り

Ohira Hideki, Isowa Tokiko, Nomura Michio, Ichikawa Naho, Kimura Kenta, Miyakoshi Makoto, Lidaka Tetsuya, Fukuyama Seisuke, Nakajima Toshihiko, Yamada Jitsuhiro

NEUROIMAGE 39 巻 ( 1 ) 頁： 500 - 514 2008年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：NeuroImage

Acute stress elicits multiple responses in autonomic, endocrine, and immune systems. Cognitive appraisal is believed to be one important modulator of such stress responses. To investigate brain substrates of crosstalks between the homeostasis-maintaining systems accompanying appraisal of stressor controllability, we simultaneously recorded regional cerebral blood flow (rCBF) using 15O-water positron emission tomography, cardiovascular indices (heart rate (HR) and blood pressure (BP)), neuroendocrine indices (concentrations of epinephrine, norepinephrine, and adrenocorticotropic hormone (ACTH) in blood), and immune indices (proportions of subsets of lymphocytes (NK cells, helper T cells, cytotoxic T cells, and B cells) in blood), in 11 male subjects who performed a mental arithmetic task with either high controllability (HC) and low controllability (LC). The LC task resulted in less sense of control in subjects than the HC task. Significant increases of rCBF in the medial and lateral orbitofrontal cortices (OFC), and in the medial and lateral prefrontal cortices (MPFC, LPFC) were observed by subtracting the HC task from the LC task. More importantly, significant positive correlations between rCBF and HR, BP, and NK cells were commonly found in the OFC and MPFC during the LC tasks, but not during the HC tasks. The present results showed for the first time that the prefrontal neural network including the OFC and MPFC might be one pivotal region for bi-directional functional association between the brain and peripheral autonomic and immune activities accompanying appraisal of an acute stressor. © 2007 Elsevier Inc. All rights reserved.

DOI： 10.1016/j.neuroimage.2007.08.017

Web of Science

Scopus

PubMed

感情鈍磨現象の2様態 : 離人症状とサイコパシーにおける感情鈍磨現象の検討査読有り

金山範明 , 大隅尚広 , 飯村里沙 , 余語真夫 , 大平英樹

パーソナリティ研究 17 巻 ( 1 ) 頁： 104-107 2008年

Psychological and physiological responses accompanying positive emotions elicited on seeing favorite persons. 査読有り

Matsunaga, M., Yamauchi, T., Nogimori, T., Konagaya, T., & Ohira, H.

The Journal of Positive Psychology ( 3 ) 頁： 192-201 2008年

Associations among central nervous, endocrine, and immune activities when positive emotions are elicited by looking at a favorite person. 査読有り

Matsunaga, M., Isowa, T., Kimura, K., Miyakoshi, M., Kanayama, N., Murakami, H., Sato, S., Konagaya, T., Nogimori, T., Fukuyama, S., Shinoda, J., Yamada, J., & Ohira, H.

Brain Behavior and Immunity ( 22 ) 頁： 408-417 2008年

Ｇｏｏｄ　ＳｌｅｅｐｅｒおよびＰｏｏｒ　Ｓｌｅｅｐｅｒにおける睡眠経過の検討

山川香織, 水田敏郎, 藤澤清, 大平英樹

人間環境学研究 6 巻 ( 2 ) 頁： 57 - 63 2008年

感情鈍磨現象の２様態―離人症状とサイコパシーにおける感情鈍磨現象の検討

金山範明, 大隅尚広, 飯村里沙, 余語真夫, 大平英樹

パーソナリティ研究 17 巻 ( 1 ) 頁： 104 - 107 2008年

感情鈍磨現象の2様態-離人症状とサイコパシーにおける感情鈍磨現象の検討パーソナリティ研究査読有り

余語真夫, 大平英樹

17 頁： 104 - 107 2008年

感情鈍磨現象の2様態 : 離人症状とサイコパシーにおける感情鈍磨現象の検討査読有り

金山範明, 大隅尚広, 飯村里沙, 余語真夫, 大平英樹

パーソナリティ研究 17 巻 ( 1 ) 頁： 104-107 2008年

Implicit change detection: Evidence from event-related brain potential

Kimura Motohiro, Katayama Junichi, Ohira Hideki

INTERNATIONAL JOURNAL OF PSYCHOLOGY 43 巻 ( 3-4 ) 頁： 318 - 318 2008年

Functional association of brain and somatic activities accompanying reversal learning

Ohira Hideki, Nomura Michio, Matsunaga Masahiro, Isowa Tokiko, Kimura Kenta, Kanayama Noriaki, Murakami Hiroki, Osumi Takahiro

PSYCHOPHYSIOLOGY 45 巻頁： S96 - S96 2008年

Functional association of brain and somatic activities accompanying reversal learning 査読有り

Hideki Ohira, Michio Nomura, Masahiro Matsunaga, Tokiko Isowa, Kenta Kimura, Noriaki Kanayama, Hiroki Murakami, Takahiro Osumi

PSYCHOPHYSIOLOGY 45 巻頁： S96 - S96 2008年

Dissociative experience and mood-dependent memory 査読有り

Kanayama, N; Sato, A; Ohira, H

COGNITION & EMOTION 22 巻 ( 5 ) 頁： 881 - 896 2008年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Cognition and Emotion

Amnesia is the main phenomenon in dissociative experiences. The present study investigated whether amnesia in participants with frequent dissociative experiences depended on state-dependent memory. Undergraduates scoring high (n = 32) or low (n = 32) on the Dissociative Experiences Scale Version-II (DES-II) participated in this experiment. Mood induction and a remember/know task were used in a typical mood-independent memory design. In the inconsistent mood state condition, participants in the high DES group showed decreased memory performance compared to the low DES group. These results were attributed to the recollection components of recognition and not to the familiarity component. Therefore we concluded that the normal population with highly frequent dissociative experiences showed strong state-dependent memory and had a memory bias in the recollection component of memory.

DOI： 10.1080/02699930701541674

Web of Science

Scopus

その他リンク： http://orcid.org/0000-0002-5576-4791

Regulation of lymphocytes redistribution via autonomic nervous activity during stochastic learning.

Kimura K, Ohira H, Isowa T, Matsunaga M, Murashima S

Brain, behavior, and immunity 21 巻 ( 7 ) 頁： 921 - 34 2007年10月

Regulation of lymphocytes redistribution via autonomic nervous activity during stochastic learning 査読有り

Kenta Kimura, Hideki Ohira, Tokiko Isowa, Masahiro Matsunaga, Seikou Murashima

BRAIN BEHAVIOR AND IMMUNITY 21 巻 ( 7 ) 頁： 921 - 934 2007年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ACADEMIC PRESS INC ELSEVIER SCIENCE

Several studies reported that redistribution of lymphocyte subsets, especially CD3-CD16+CD56+ natural killer (NK) cells, was elicited by acute psychological stress tasks. It is known that lymphocyte redistribution was regulated based on active or passive emotional coping strategies, which can be elicited dependent on controllability of a stressor. Controllability can be evaluated gradually by learning of a contingency between actions and outcomes. Therefore, lymphocyte redistribution can be determined by learning of the contingency. To examine this issue, we used a stochastic learning task as an acute stress task and divided twenty healthy participants into reinforcement or yoked groups. Between the two groups, only whether they could learn the contingency was manipulated. As a result, patterns of changes in the NK cell numbers differed between the groups; NK cells remarkably increased at first and then gradually decreased to the baseline in the reinforcement group while the yoked group showed a moderate but sustained increase of NK cells. These patterns of changes in the NK cells were completely parallel with changes of the cardiovascular parameters but not with secretion of catecholamines. The present results suggest that cardiovascular and immune reactivity can be modulated along with progresses of adaptation for an acute stressor. (C) 2007 Elsevier Inc. All rights reserved.

DOI： 10.1016/j.bbi.2007.03.004

Web of Science

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