研究者詳細 - 田岡　俊昭

Application of susceptibility weighted imaging (SWI) for evaluation of draining veins of arteriovenous malformation: utility of magnitude images.

Miyasaka T, Taoka T, Nakagawa H, Wada T, Takayama K, Myochin K, Sakamoto M, Ochi T, Akashi T, Kichikawa K

Neuroradiology 54 巻 ( 11 ) 頁： 1221 - 7 2012年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Neuroradiology

Introduction: The current study evaluated the signal characteristics of susceptibility weighted imaging (SWI) of arteriovenous malformation (AVM), especially for draining veins. For this purpose, we identified the draining veins of the AVM on angiography and evaluated the signal on magnitude image for SWI (SWI-mag) and minimum intensity projection image (SWI-minIP). Methods: Subjects were 14 cases with angiographically proven AVM. SWI-mag, SWI-minIP, and time-of-flight (TOF) magnetic resonance angiography were acquired. For the draining veins of the AVM identified on angiography, we analyzed signal intensity on the images listed above, and classified it into hyperintensity (hyper), mixed intensity (mixed), hypointensity (hypo), and no visualization. Results: On the analysis of 27 angiographically proven draining veins, 19 draining veins were classified as hyper, 3 as mixed, 0 as hypo, and 6 as no visualization on SWI-mag. On TOF images, 21 draining veins were classified as hyper, 2 as mixed, 0 as hypo, and 4 as no visualization, while 6 draining veins did not show hyperintensity on TOF, and SWI-mag visualized 3 of these 6 veins as hyper. Conclusion: SWI-mag depicted most draining veins of AVM as hyperintensity. We speculate that this is mainly due to the higher concentration of oxygenated hemoglobin (oxy-Hb) and inflow effect of the draining vein. SWI-mag seems to be useful in the analysis and follow-up for AVM as the signal on the image may reflect physiological status. © 2012 Springer-Verlag.

DOI： 10.1007/s00234-012-1029-5

頭蓋内静脈逆流を伴う硬膜動静脈瘻におけるSusceptibility-Weighted Imagingの有用性治療前後での頭蓋内静脈逆流と静脈うっ血の評価

中川一郎, 和田敬, 中川裕之, 西村文彦, 弘中康雄, 本山靖, 朴永銖, 田岡俊昭, 吉川公彦, 中瀬裕之

JNET: Journal of Neuroendovascular Therapy 6 巻 ( 5 ) 頁： 233 - 233 2012年11月

Investigation of donepezil effect to the prevention of hippocamal volume loss in alzheimer's disease 査読有り

Kitamura, S; Kiuchi, K; Taoka, T; Morikawa, M; Inoue, M; Kosaka, J; Hashimoto, K; Nagashima, T; Matsuoka, K; Kichikawa, K; Kishimoto, T

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY 15 巻頁： 172 - 173 2012年6月

Branching pattern of lenticulostriate arteries observed by MR angiography at 3.0 T.

Akashi T, Taoka T, Ochi T, Miyasaka T, Wada T, Sakamoto M, Takewa M, Kichikawa K

Japanese journal of radiology 30 巻 ( 4 ) 頁： 331 - 5 2012年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Japanese Journal of Radiology

Purpose We hypothesized that the pattern of branching of the lenticulostriate arteries (LSAs) is involved in the variation of the distribution of the infarction within the LSA region. Our purpose was to evaluate the visibility of LSAs in 3D time-of-fiight (TOF) MR angiography (MRA) with a 3.0 T scanner and to investigate the branching patterns of LSAs. Materials and methods We performed 3D TOF MRA at 3.0 T for 100 healthy subjects. We assessed the number of LSAs and the number of branches arising from each LSA by evaluating MRA source images. Results In 200 hemispheres, 330 LSAs were visualized (mean = 1.65/hemisphere). In 3.5% of all hemispheres, no LSA was depicted; one LSA was depicted in 39%, two in 46.5%, and three in 11%. The maximum number of depicted LSA branches was five in 2% of all subjects, four in 7%, three in 26%, and two in 49% (mean = 2.3/subject). A large LSA trunk with three or more branches was found in 35% of subjects. Conclusion Visualization of LSAs was possible in 96.5% of subjects by use of 3.0 T MRA. LSA branching patterns were variable, and a large LSA trunk with three or more branches was common. © 2012 Japan Radiological Society.

DOI： 10.1007/s11604-012-0058-7

Diffuse vascular injury: convergent-type hemorrhage in the supratentorial white matter on susceptibility-weighted image in cases of severe traumatic brain damage.

Iwamura A, Taoka T, Fukusumi A, Sakamoto M, Miyasaka T, Ochi T, Akashi T, Okuchi K, Kichikawa K

Neuroradiology 54 巻 ( 4 ) 頁： 335 - 43 2012年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Neuroradiology

Introduction: Susceptibility-weighted image (SWI) is one of the most sensitive methods for detect microbleeding and useful for evaluation of traumatic brain damage. The purpose of this study is to delineate the characteristics and importance of supratentorial deep white matter hemorrhages detected by SWI in cases of traumatic brain damage. Methods: Twenty-one consecutive cases with severe traumatic head injury were included in the current study. MRI examinations were made within 1 month after injury. We evaluated the degree and distribution of the supratentorial hemorrhages on SWI retrospectively. We classified the degree of bleeding into four grades: "small hemorrhage," "single bead-like hemorrhage," "convergent-type hemorrhage," and "massive hemorrhage." We then correlated the degree and distribution of the hemorrhage to clinical outcomes. We also evaluated the apparent diffusion coefficient (ADC) image of lobes with "convergent-type hemorrhage." Results: Existence of "massive hemorrhage" correlated with a poor outcome, that is, worse than "severely disabled" on the Glasgow Outcome Scale. The number of lobes affected by "convergent-type hemorrhage" also correlated with poor outcome. There were 45 lobes with "convergent-type hemorrhage" and 27 of them showed increased diffusivity on ADC images. Conclusion: Supratentorial massive hemorrhages and supratentorial convergent-type multiple hemorrhages were associated with poor prognosis after traumatic brain injury. The increased diffusivity in lobes with convergent-type hemorrhages may indicate that congestion of the proximal medullary vein may play some role for these hemorrhages. © Springer-Verlag 2011.

DOI： 10.1007/s00234-011-0892-9

Comparison of computed tomography myelography and radioisotope cisternography to detect cerebrospinal fluid leakage in spontaneous intracranial hypotension.

Hashizume K, Watanabe K, Kawaguchi M, Taoka T, Shinkai T, Furuya H

Spine 37 巻 ( 4 ) 頁： E237 - 42 2012年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Spine

Study Design: A retrospective observational study. Objective: To compare the usefulness of radioisotope cisternography (RIC) and computed tomography myelography (CTM) for the detection of cerebrospinal fluid (CSF) leakage in spontaneous intracranial hypotension (SIH). Summary of Background Data: CSF leakage sites have been generally identified by RIC in patients with SIH. Although a number of reports have recently indicated the usefulness of CTM, whether RIC or CTM more reliably detects leakage sites has not been decided because the 2 tests have not been directly compared. Methods: Both RIC and CTM were performed, and the findings were compared in 12 patients with SIH strictly meeting the second edition of the International Classification of Headache Disorders diagnostic criteria. Results: On RIC, the detection rate of leakage including indirect signs, an early vesicular radioisotope (RI) accumulation and delayed ascent of the RI to the cerebral convexity, was observed in 100%, but that of the direct sign, paraspinal RI accumulation, was in 8 patients (67%). On CTM, the epidural collection of intraspinally administered contrast medium was demonstrated in all patients (100%), and the collection site was located in the cervical and thoracic vertebral regions in most cases. When RIC and CTM findings were collated, paraspinal accumulation in the cervical and thoracic regions on RIC corresponded to the entire or a part of the findings on CTM. In contrast, in 4 of 5 patients with paraspinal accumulation in the lumbosacral region, epidural collection was not noted in this region on CTM. Conclusion: In patients with SIH, epidural collection on CTM may more accurately demonstrate CSF leakage compared with paraspinal RI accumulation on RIC. Copyright © 2012 Lippincott Williams & Wilkins. Unauthorized reproduction of this article is prohibited.

DOI： 10.1097/BRS.0b013e31822e606a

Visualizing Non-Gaussian Diffusion: Clinical Application of q-Space Imaging and Diffusional Kurtosis Imaging of the Brain and Spine 査読有り

小児脳幹被蓋部の分水嶺

堀沙恵香, 田岡俊昭, 越智朋子, 明石敏昭, 坂本雅彦, 和田敬, 吉川公彦, 内田優美子, 高橋幸博

日本医学放射線学会学術集会抄録集 71回巻頁： S130 - S130 2012年2月

Hori, M; Fukunaga, I; Masutani, Y; Taoka, T; Kamagata, K; Suzuki, Y; Aoki, S

MAGNETIC RESONANCE IN MEDICAL SCIENCES 11 巻 ( 4 ) 頁： 221 - 233 2012年

"DWI-SWI" Mismatch May Represent an Acute Ischemic Penumbra with Misery Perfusion 査読有り

Fujioka, M; Takahashi, M; Tada, Y; Asai, H; Iwamura, A; Ito, S; Watanabe, T; Kawai, Y; Seki, T; Fukushima, H; Urizono, Y; Hata, M; Akashi, T; Taoka, T; Okuchi, K

CEREBROVASCULAR DISEASES 34 巻頁： 79 - 79 2012年

DWMRI Study Reveals Late-Onset Cytotoxic Edema in the Pulvinar and Medial Nuclei of Thalami in Human Brains after Hypoglycemic Injury: Possible Remote Effects of Axonal and Transsynaptic Mechanism 査読有り

Fujioka, M; Ito, S; Tada, Y; Iwamura, A; Kawai, Y; Seki, T; Urizono, Y; Suzuki, S; Kitazawa, Y; Hata, M; Taoka, T; Okuchi, K

CEREBROVASCULAR DISEASES 34 巻頁： 43 - 43 2012年

Diffusion Kurtosis Image of the Cerebral Infarction: Increased Axial Diffusion Kurtosis 査読有り

Taoka, T; Fujioka, M; Sakamoto, M; Akashi, T; Miyasaka, T; Ochi, T; Hori, S; Wada, T; Uchikoshi, M; Kichikawa, K

CEREBROVASCULAR DISEASES 34 巻頁： 81 - 81 2012年

Global Brain Ischemia-Reperfusion Induces Striatal T1-Hyperintensity of Neuronal Death without Microbleeds in Human Brains: SWI Study on Cardiac Arrest Survivors 査読有り

Fujioka, M; Tsuruta, K; Iwamura, A; Watanabe, T; Fukushima, H; Urizono, Y; Hata, M; Sakamoto, M; Taoka, T; Okuchi, K

CEREBROVASCULAR DISEASES 34 巻頁： 60 - 60 2012年

The Use of Susceptibility-Weighted Imaging as an Indicator of Retrograde Leptomeningeal Venous Drainage with Dural Arteriovenous Fistula 査読有り

Nakagawa, I; Nishimura, F; Hironaka, Y; Yamada, S; Motoyama, Y; Park, YS; Taoka, T; Wada, T; Nakagawa, H; Kichikawa, K; Nakase, H

CEREBROVASCULAR DISEASES 34 巻頁： 42 - 43 2012年

Discrepancy in T <inf>1</inf> and T <inf>2</inf> shortening of the globus pallidus in hepatic insufficiency: Evaluation by susceptibility-weighted imaging

Ochi T., Taoka T., Akashi T., Sakamoto M., Miyasaka T., Wada T., Nakagawa H., Takehana K., Tatsuno K., Kichikawa K.

Magnetic Resonance in Medical Sciences 10 巻 ( 2 ) 頁： 79 - 83 2011年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Magnetic Resonance in Medical Sciences

Purpose: We assessed the signal of the globus pallidus (GP) in cases of hepatic in-sufficiency, especially to evaluate the degree of discrepancy in paramagnetic effects on shortening of T 1 and T 2* using susceptibility-weighted images (SWI). Materials and Methods: Seven patients with hepatic insufficiency underwent magnetic resonance (MR) examinations that included T 1-weighted images (T 1WI), T 2-weighted images (T 2WI), and SWI on a 1.5-tesla MR imager, and we compared their results to those of controls. On T 1WI and T 2WI, we measured signal intensity in the GP and posterior segment of the putamen (Put) to obtain a signal ratio (GP/Put ratio), and on SWI, we classified signal intensity into 4 grades: A, higher than the cortex; B, lower than the cortex and higher than the cerebrospinal fluid (CSF); C, lower than the CSF and higher than the red nucleus; and D, lower than the red nucleus. Results: In the 7 patients with hepatic insufficiency, the mean GP/Put ratio was significantly higher on T 1WI and T 2WI than those values in controls. On SWI, we classified 2 cases each as Grade A, Grade B, and Grade C, and one as Grade D. Although the signal of the GP was elevated on T 1WI, there was no decrease in signal on T 2WI. On SWI, we obtained no low signal intensity. Conclusion: In patients with hepatic insufficiency, the globus pallidus did not show low signal intensity on either T 2WI or SWI. Hyperintensity of the GP on T 1WI without hypoin-tensity on T 2WI, or even SWI, suggests a discrepancy between paramagnetic effect on T 1 and T 2 shortening that reflects the accumulation of manganese and the presence of hepatic insufficiency.

DOI： 10.2463/mrms.10.79

Adjunctive techniqueを用いた脳動脈瘤の瘤内塞栓

Tumefactive demyelinating disease(≧30mm)の神経放射線学的およびウイルス学的検討

桐山敬生, 形岡博史, 田岡俊昭, 殿村恭代, 守川公美, 川原誠, 杉江和馬, 降矢芳子, 吉川公彦, 上野聡

臨床神経学 51 巻 ( 12 ) 頁： 1221 - 1221 2011年12月

中川裕之, 宮坂俊輝, 明珍薫, 和田敬, 坂本雅彦, 高山勝年, 田岡俊昭, 吉川公彦, 中川一郎, 内山佳知

JNET: Journal of Neuroendovascular Therapy 5 巻 ( 4 ) 頁： 253 - 253 2011年11月

FilterWire EZを用いた頸動脈ステント留置術初期治療成績

和田敬, 高山勝年, 中川裕之, 宮坂俊輝, 明珍薫, 坂本雅彦, 田岡俊昭, 中川一郎, 黒川紳一郎, 中瀬裕之, 吉川公彦

JNET: Journal of Neuroendovascular Therapy 5 巻 ( 4 ) 頁： 257 - 257 2011年11月

頭蓋内静脈逆流を伴う硬膜動静脈瘻におけるSusceptibility Weighted Imagingの有用性

中川一郎, 和田敬, 中川裕之, 弘中康雄, 本山靖, 朴永銖, 田岡俊昭, 吉川公彦, 中瀬裕之

JNET: Journal of Neuroendovascular Therapy 5 巻 ( 4 ) 頁： 270 - 270 2011年11月

Asymmetry, sex differences and age-related changes in the white matter in the healthy elderly: a tract-based study.

Kitamura S, Morikawa M, Kiuchi K, Taoka T, Fukusumi M, Kichikawa K, Kishimoto T

BMC research notes 4 巻 ( 1 ) 頁： 378 2011年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC Research Notes

Background: Hemispherical asymmetry, sex differences and age-related changes have been reported for the human brain. Meanwhile it was still unclear the presence of the asymmetry or sex differences in the human brain occurred whether as a normal development or as consequences of any pathological changes. The aim of this study was to investigate hemispherical asymmetry, sex differences and age-related changes by using a tract-based analysis in the nerve bundles. Methods. 40 healthy elderly subjects underwent magnetic resonance diffusion tensor imaging, and we calculated fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values along the major white matter bundles. Results: We identified hemispherical asymmetry in the ADC values for the cingulate fasciculus in the total subject set and in males, and a sex difference in the FA values for the right uncinate fasciculus. For age-related changes, we demonstrated a significant increase in ADC values with advancing age in the right cingulum, left temporal white matter, and a significant decrease in FA values in the right superior longitudinal fasciculus. Conclusion: In this study, we found hemispherical asymmetry, sex differences and age-related changes in particular regions of the white matter in the healthy elderly. Our results suggest considering these differences can be important in imaging studies. © 2010 Kitamura et al; licensee BioMed Central Ltd.

DOI： 10.1186/1756-0500-4-378