研究者詳細 - 田岡　俊昭

論文 - 田岡　俊昭

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Diffusion tensor imaging in cases with visual field defect after anterior temporal lobectomy 査読有り

T Taoka, M Sakamoto, S Iwasaki, H Nakagawa, A Fukusumi, S Hirohashi, K Taoka, K Kichikawa, T Hoshida, T Sakaki

AMERICAN JOURNAL OF NEURORADIOLOGY 26 巻 ( 4 ) 頁： 797 - 803 2005年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：AMER SOC NEURORADIOLOGY

BACKGROUND AND PURPOSE: Visual defect due to optic radiation injury is a complication of temporal lobectomy for temporal epilepsy. To investigate whether diffusion tensor imaging can delineate the changes in optic radiations after lobectomy, we evaluated parameters on tensor images for optic radiations and correlated them with visual defect.
METHODS: We examined 14 cases after temporal lobectomy. Durations after surgeries ranged from 3 weeks to 9 years. The cases were classified into three groups on the basis of the severity of visual field defect (A-C, with group C the most severe). We evaluated signals on T2-weighted images and parameters of tensor images, including fractional anisotropy (FA) and apparent diffusion coefficient (ADC), for the optic radiation in both the operated and intact side.
RESULTS: On T2-weighted images, high signals in optic radiations were seen in four cases, occurring more than 4 weeks after surgery. The mean operated-to-intact side FA ratio in the optic radiation decreased according to severity of visual defect (group A, 0.88; group B, 0.89; group C, 0.73). The mean operated-to-intact side ADC ratio showed no significant difference in the overall cases. The ratio for ADC, however, tended to increase according to visual defect in cases after 10 weeks postsurgery.
CONCLUSION. Optic radiation showed a decreased FA value in cases after temporal lobectomy. In later stages, ADC values tended to increase and high signal intensities on T2-weighted images were observed. The FA value can be used for evaluating Wallerian degeneration of optic radiation even in the early stages after surgery.

Web of Science

Evaluation of delayed image of 18F FDG-PET in diagnosis of pulmonary lesions

Sakamoto M., Imai T., Shingai T., Nishimoto Y., Taoka T., Koukawa K., Hirohashi S., Yoshimura H., Yoshikawa K.

Japanese Journal of Clinical Radiology 50 巻 ( 1 ) 頁： 148 - 154 2005年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Japanese Journal of Clinical Radiology

We evaluated the usefulness of dual time point 18F-FDG PET by comparing two groups of pulmonary lesions (38 malignant tumors and 29 benign lesions). Among standardized uptake value (SUV) of early image (SUVe), SUV of delayed image (SUVd), Retention Index (RI), and SUVe combined with RI (SUVe-RI), diagnosis by SUVe-RI revealed the best result (sensitivity: 78.9%, specificity: 82.8%). We conclude that dual time point FDG-PET is better method than early or delayed single acquisition to diagnose pulmonary lesions.

Scopus

Evaluation of extraocular muscles using dynamic contrast enhanced MRI in patients with chronic thyroid orbitopathy.

Taoka T, Sakamoto M, Nakagawa H, Fukusumi A, Iwasaki S, Taoka K, Kichikawa K

Journal of computer assisted tomography 29 巻 ( 1 ) 頁： 115 - 20 2005年1月

Evaluation of extraocular muscles using dynamic contrast enhanced MRI in patients with chronic thyroid orbitopathy

Taoka T., Sakamoto M., Nakagawa H., Fukusumi A., Iwasaki S., Taoka K., Kichikawa K.

Journal of Computer Assisted Tomography 29 巻 ( 1 ) 頁： 115 - 120 2005年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Computer Assisted Tomography

Objective: The purpose of the current study is to investigate the underlying pathophysiological changes of extraocular muscle (EOM) in Graves orbitopathy using dynamic contrast MR imaging and to correlate these MR functional changes with the anatomic abnormalities. Methods: EOMs of 16 patients with Graves disease and 12 normal volunteers were examined by dynamic enhanced MRI. We quantified the peak enhancement ratio of EOMs and calculated the ratio versus temporalis muscle and the ratio of maximum upslope versus temporalis muscle. We compared the ratios between normal volunteers and patient groups. Results: Mean of peak enhancement ratio values for the EOMs in patients with Graves disease tends to decrease according to the severity of the anatomic and clinical changes. The mean maximum upslope also decreased according to the severity of the disease for EOMs. Conclusion: Hemodynamic information obtained by dynamic contrast enhanced MRI is useful in evaluating the clinical course of thyroid orbitopathy.

DOI： 10.1097/01.rct.0000146112.56194.24

Scopus

Evaluation of extraocular muscles using dynamic contrast enhanced MRI in patients with chronic thyroid orbitopathy 査読有り

T Taoka, M Sakamoto, H Nakagawa, A Fukusumi, A Iwasaki, K Taoka, K Kichikawa

JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 29 巻 ( 1 ) 頁： 115 - 120 2005年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Objective: The purpose of the current study is to investigate the underlying pathophysiological changes of extraocular muscle (EOM) in Graves orbitopathy using dynamic contrast MR imaging and to correlate these MR functional changes with the anatomic abnormalities.
Methods: EOMs of 16 patients with Graves disease and 12 normal volunteers were examined by dynamic enhanced MRI. We quantified the peak enhancement ratio of EOMs and calculated the ratio versus temporalis muscle and the ratio of maximum upslope versus temporalis muscle. We compared the ratios between normal volunteers and patient groups.
Results: Mean of peak enhancement ratio values for the EOMs in patients with Graves disease tends to decrease according to the severity of the anatomic and clinical changes. The mean maximum upslope also decreased according to the severity of the disease for EOMs.
Conclusion: Hemodynamic information obtained by dynamic contrast enhanced MRI is useful in evaluating the clinical course of thyroid orbitopathy.

DOI： 10.1097/01.rct.0000146112.56194.24

Web of Science

Proton MR spectroscopy of adult-onset dentatorubral-pallidoluysian atrophy. Open Access

Kin T, Hirano M, Taoka T, Takamure M, Furiya Y, Kichikawa K, Ueno S

Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine 4 巻 ( 3 ) 頁： 123 - 7 2005年

Proton MR Spectroscopy of Adult-onset Dentatorubral-pallidoluysian Atrophy Open Access

KIN Tesseki, HIRANO Makito, TAOKA Toshiaki, TAKAMURE Miwa, FURIYA Yoshiko, KICHIKAWA Kimihiko, UENO Satoshi

Magnetic Resonance in Medical Sciences 4 巻 ( 3 ) 頁： 123 - 127 2005年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Japanese Society for Magnetic Resonance in Medicine

Purpose: To quantify impairment of the basal ganglia (globus pallidus and thalamus) in adult-onset dentatorubral-pallidoluysian atrophy (DRPLA). Methods: Five patients with genetically definite adult-onset DRPLA (aged 51 to 65 years, mean 55.6 years) and 5 age- and sex-matched healthy controls underwent conventional magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (MRS) of the brain in the voxels predominantly containing the globus pallidus or the thalamus. Results: Conventional MRI studies showed apparently normal intensities in the globus pallidus and thalamus. MRS showed that the choline (Cho)/creatine (Cr) ratio for the patients' globus pallidus, the region preferentially affected in DRPLA, was significantly higher than that in the controls (p<0.05). The N-acetylaspartate (NAA)/Cr ratio for the globus pallidus and the Cho/Cr and NAA/Cr ratios for the thalamus, the region relatively spared in this disease, did not differ significantly between the patients and controls. Conclusions: MRS may sensitively and specifically detect biochemical alterations in susceptible regions of patients with adult-onset DRPLA.

DOI： 10.2463/mrms.4.123

Open Access

CiNii Research

軽度脳虚血による遅発性神経細胞死と進行性認知障害

藤岡政行, 田岡俊昭, 松尾嘉之, 三島健一, 御興久美子, 近藤洋一, 津田聖一, 吉川哲也, 藤原道弘, 浅野孝雄, 榊寿右, 宮崎章宏, Darren Park, Bo, K. Siesjo

脳循環代謝頁： 17, 53 - 60 2005年

後頭葉外側皮質の視野地図

開道貴信, 星田徹, 田岡俊昭, 榊寿右

CI研究 : progress in computed imaging 26 巻 ( 3 ) 頁： 139 - 143 2004年12月

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion

Tada, H; Takanashi, J; Barkovich, AJ; Oba, H; Maeda, M; Tsukahara, H; Suzuki, M; Yamamoto, T; Shimono, T; Ichiyama, T; Taoka, T; Sohma, O; Yoshikawa, H; Kohno, Y

NEUROLOGY 63 巻 ( 10 ) 頁： 1854 - 1858 2004年11月

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion

Tada H., Takanashi J.I., Barkovich A.J., Oba H., Maeda M., Tsukahara H., Suzuki M., Yamamoto T., Shimono T., Ichiyama T., Taoka T., Sohma O., Yoshikawa H., Kohno Y.

Neurology 63 巻 ( 10 ) 頁： 1854 - 1858 2004年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Neurology

Objective: To clarify whether patients with clinical diagnoses of encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum (SCC) share common clinical features. Methods: Possible encephalitis/ encephalopathy patients; with a reversible isolated SCC lesion on MRI were collected retrospectively. Their clinical, laboratory, and radiologic data were reviewed. Results: Fifteen encephalitis/encephalopathy patients with a reversible isolated SCC lesion were identified among 22 patients referred for this study. All 15 patients had relatively mild clinical courses. Twelve of the 15 patients had disorders of consciousness. Eight patients had seizures, and three of them received antiepileptic drugs. All 15 patients clinically recovered completely within 1 month (8 patients within a week) after the onset of neurologic symptoms. The SCC lesion was ovoid in six patients; it extended irregularly from the center to the lateral portion of SCC in the other eight patients. Homogeneously reduced diffusion was seen in all seven patients who underwent diffusion-weighted imaging. There was no enhancement in the five patients so examined. The SCC lesion had completely disappeared in all patients at follow-up MRI exams between 3 days and 2 months after the initial MRI (within 1 week in eight patients). Conclusion: The clinical features among the affected patients were nearly identical, consisting of relatively mild CNS manifestations and complete recovery within 1 month.

DOI： 10.1212/01.WNL.0000144274.12174.CB

Scopus

Paradoxical parasellar high signals resembling shunt diseases on routine 3D time-of-flight MR angiography of the brain: mechanism for the signals and differential diagnosis from shunt diseases. 国際誌

Sakamoto M, Taoka T, Iwasaki S, Nakagawa H, Fukusumi A, Takayama K, Wada T, Kichikawa K

Magnetic resonance imaging 22 巻 ( 9 ) 頁： 1289 - 93 2004年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Magnetic Resonance Imaging

We occasionally encounter phenomena in which venous flow signals of the cavernous sinus (CS) and/or inferior petrosal sinus (IPS) are visualized paradoxically in patients without arteriovenous shunt in 3D time-of-flight magnetic resonance angiography (3D-TOF MRA) of the brain. The aims of this study are to examine the frequency and cause of this phenomenon ("pseudo- shunt" image) and to determine points of differentiation from definite arteriovenous shunt images ("real shunt"). We retrospectively examined 85 maximum intensity projection images obtained by MRA in the absence of arteriovenous shunts to detect pseudo-shunt images, and evaluated source images of pseudo-shunt studies for venous structures. Four real-shunt MRA studies were compared with pseudo-shunt studies on three points: (1) extension of sinuses, (2) extension of cortical veins, and (3) signal intensity of sinuses as assessed by the scoring method (1 point when these findings exist, 0 when they do not). We detected five CS (3%) and six IPS (4%) signals in 9 (11%) of the 85 cases. In the source images of four pseudo-shunt images in the CS, we detected signals from the sphenoparietal sinus (SPS). The average score was significantly lower in the pseudo-shunt (0.22) than the real-shunt (2.75) images (P<.0001). In cerebral 3D-TOF MRA, pseudo-shunt images were seen in 11% (9/85) of the study population, with antegrade upward blood flow of the SPS considered as one of the causes. Real-shunt signals can be distinguished from pseudo-shunt signals by evaluation of source images. © 2004 Elsevier Inc. All rights reserved.

DOI： 10.1016/j.mri.2004.08.004

Web of Science

Scopus

PubMed

Clinically mild encephalitis/encephalopathy with a reversible splenial lesion 査読有り

H Tada, J Takanashi, AJ Barkovich, H Oba, M Maeda, H Tsukahara, M Suzuki, T Yamamoto, T Shimono, T Ichiyama, T Taoka, O Sohma, H Yoshikawa, Y Kohno

NEUROLOGY 63 巻 ( 10 ) 頁： 1854 - 1858 2004年11月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS

Objective: To clarify whether patients with clinical diagnoses of encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum (SCC) share common clinical features. Methods: Possible encephalitis/encephalopathy patients with a reversible isolated SCC lesion on MRI were collected retrospectively. Their clinical, laboratory, and radiologic data were reviewed. Results: Fifteen encephalitis/encephalopathy patients with a reversible isolated SCC lesion were identified among 22 patients referred for this study. All 15 patients had relatively mild clinical courses. Twelve of the 15 patients had disorders of consciousness. Eight patients had seizures, and three of them received antiepileptic drugs. All 15 patients clinically recovered completely within 1 month ( 8 patients within a week) after the onset of neurologic symptoms. The SCC lesion was ovoid in six patients; it extended irregularly from the center to the lateral portion of SCC in the other eight patients. Homogeneously reduced diffusion was seen in all seven patients who underwent diffusion-weighted imaging. There was no enhancement in the five patients so examined. The SCC lesion had completely disappeared in all patients at follow-up MRI exams between 3 days and 2 months after the initial MRI ( within 1 week in eight patients). Conclusion: The clinical features among the affected patients were nearly identical, consisting of relatively mild CNS manifestations and complete recovery within 1 month.

DOI： 10.1212/01.WNL.0000144274.12174.CB

Web of Science

Retinotopy with coordinates of lateral occipital cortex in humans. 国際誌

Kaido T, Hoshida T, Taoka T, Sakaki T

Journal of neurosurgery 101 巻 ( 1 ) 頁： 114 - 8 2004年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Neurosurgery

Object. The lateral occipital cortex in humans is known as the "extrastriate visual cortex." It is, however, an unexplored field of research, and the anatomical nomenclature for its surface has still not been standardized. This study was designed to investigate whether the lateral occipital cortex in humans has retinotopic representation. Methods. Four right-handed patients with a diagnosis of intractable epilepsy from space-occupying lesions in the occipital lobe or epilepsy originating in the occipital lobe received permanently implanted subdural electrodes. Electrical cortical stimulation was applied directly applied to the brain through metal electrodes by using a biphasic stimulator. The location of each electrode was measured on a lateral skull x-ray study. Each patient considered a whiteboard with vertical and horizontal median lines. The patient was asked to look at the midpoint on the whiteboard. If a visual hallucination or illusion occurred, the patient recorded its outline, shape, color, location, and motion on white paper one tenth the size of, and with vertical and horizontal median lines similar to those on, the whiteboard. Polar angles and eccentricities of the mid-points of the phosphenes from the coordinate origin were measured on the paper. On stimulation of the lateral occipital lobe, 44 phosphenes occurred. All phosphenes were circular or dotted, with a diameter of approximately 1 cm, except one that was like a curtain in the peripheral end of the upper and lower visual fields on stimulation of the parietooccipital region. All phosphenes appeared in the visual field contralateral to the cerebral hemisphere stimulated. On stimulation of the lateral occipital lobe, 22 phosphenes moved centrifugally or toward a horizontal line. From three-dimensional scatterplots and contour maps of the polar angles and eccentricities in relation to the x-ray coordinates of the electrodes, one can infer that the lateral occipital cortex in humans has retinotopic representation. Conclusions. The authors found that phosphenes induced by electrical cortical stimulation of the lateral occipital cortex represent retinotopy. From these results one can assert that visual field representation with retinotopic relation exists in the extrastriate visual cortex.

DOI： 10.3171/jns.2004.101.1.0114

Web of Science

Scopus

PubMed

Progressive MRI changes indicating inflammatory neurodegeneration with cognitive decline induced by ischemic stress 査読有り

Fujinka, M; Taoka, T; Matsuo, Y; Mishima, M; Ogoshi, K; Kondo, Y; Asano, I; Fujiwara, M; Sakaki, T; Miyasaki, A; Park, D; Siesjo, BK

STROKE 35 巻 ( 6 ) 頁： E323 - E323 2004年6月

Distinguishing between anterior cerebral artery and middle cerebral artery perfusion by color-coded perfusion direction mapping with arterial spin labeling. 国際誌

Taoka T, Iwasaki S, Nakagawa H, Fukusumi A, Hirohashi S, Sakamoto M, Kichikawa K, Murata K

AJNR. American journal of neuroradiology 25 巻 ( 2 ) 頁： 248 - 51 2004年2月

Signal characteristics of FLAIR related to water content: comparison with conventional spin echo imaging in infarcted rat brain. 国際誌

Taoka T, Fujioka M, Matsuo Y, Notoya M, Iwasaki S, Fukusumi A, Nakagawa H, Sakamoto M, Kichikawa K, Ohishi H

Magnetic resonance imaging 22 巻 ( 2 ) 頁： 221 - 7 2004年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Magnetic Resonance Imaging

To examine the correlation between tissue water content and signal intensity on fluid-attenuated inversion recovery (FLAIR) images, we analyzed infarcted rat brain, verified the results by theoretical simulation, and compared them with conventional spin-echo images. We produced brain infarction with cavitation in five rats by middle cerebral artery occlusion. After in vivo MRI, histologic sections of the MRI plane were obtained. We measured the signal intensity of regions on FLAIR and spin-echo images, and measured the area of cavitation on histologic sections. We plotted curves of cavity percentage to signal intensity. Theoretical values were calculated using a two- compartment model. On the curve of cavity area to signal intensity, the signal on FLAIR images peaked in tissues with 20% to 30% area of cavitation. On the theoretical curve, the signal on FLAIR images peaked at 90% tissue water content. These results seem to be characteristic of FLAIR. © 2004 Elsevier Inc. All rights reserved.

DOI： 10.1016/j.mri.2003.09.004

Web of Science

Scopus

PubMed

Distinguishing between anterior cerebral artery and middle cerebral artery perfusion by color-coded perfusion direction mapping with arterial spin labeling 査読有り

T Taoka, S Iwasaki, H Nakagawa, A Fukusumi, S Hirohashi, M Sakamoto, K Kichikawa, K Murata

AMERICAN JOURNAL OF NEURORADIOLOGY 25 巻 ( 2 ) 頁： 248 - 251 2004年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：AMER SOC NEURORADIOLOGY

The purpose of this study was to evaluate collateral circulation by describing anterior cerebral artery and middle cerebral artery perfusion areas. Pairs of image sets spin labeled on the medial and lateral side were used. A pixel-by-pixel t test was performed, with blue gradation used to display lateral perfusion (ie, middle cerebral artery) and orange gradation for anterior cerebral artery perfusion. Extensions of anterior cerebral artery perfusion areas in cases of middle cerebral artery stenosis were described. This method may aid in estimation of collateral circulation for stroke treatment.

Web of Science

Distinguishing between Anterior Cerebral Artery and Middle Cerebral Artery Perfusion by Color-Coded Perfusion Direction Mapping with Arterial Spin Labeling

Taoka T., Iwasaki S., Nakagawa H., Fukusumi A., Hirohashi S., Sakamoto M., Kichikawa K., Murata K.

American Journal of Neuroradiology 25 巻 ( 2 ) 頁： 248 - 251 2004年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：American Journal of Neuroradiology

Scopus

Imaging and management of acute stroke 査読有り

WC Yuh, T Taoka, T Ueda, M Maeda

DISEASES OF THE BRAIN, HEAD AND NECK, SPINE 頁： 20 - 26 2004年

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