Faculty Profiles - UCHIDA Hiroo

Papers - UCHIDA Hiroo

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P-143 突然の小腸穿孔で発症したクロストリディウム腸炎の1例(示説十二指腸・小腸1) Reviewed

川嶋寛, 岩中督, 内田広夫, 西明, 工藤寿美, 佐竹亮介, 岸本宏志

日本小児外科学会雑誌 Vol. 40 ( 3 ) page： 509 - 509 2004

1. 腹腔鏡下噴門形成術の再発症例に対する腹腔鏡下手術(セッション8 ミニシンポジウム1 : 内視鏡手術における合併症の予防と対処法)(第23回日本小児外科手術手技・小児内視鏡手術研究会) Reviewed

川嶋寛, 岩中督, 内田広夫, 西明, 工藤寿美, 佐竹亮介

日本小児外科学会雑誌 Vol. 40 ( 1 ) page： 160 - 160 2004

2. 腹腔鏡下造肛術時の膣,尿道の同定の工夫(セッション9 腹腔鏡,手術手技 : 直腸肛門・泌尿生殖器1)(第23回日本小児外科手術手技・小児内視鏡手術研究会) Reviewed

西明, 岩中督, 内田広夫, 川嶋寛, 工藤寿美, 佐竹亮介

日本小児外科学会雑誌 Vol. 40 ( 1 ) page： 162 - 162 2004

14. 術後直腸狭窄に対する経肛門的狭窄切開術の経験(第30回日本小児内視鏡研究会) Reviewed

西明, 岩中督, 内田広夫, 川嶋寛, 工藤寿美, 佐竹亮介

日本小児外科学会雑誌 Vol. 40 ( 2 ) page： 223 - 224 2004

11. ITPに対する腹腔鏡下脾摘術中の血小板数の変動について(第17回日本小児脾臓研究会) Reviewed

西明, 岩中督, 内田広夫, 川嶋寛, 工藤寿美, 佐竹亮介

日本小児外科学会雑誌 Vol. 40 ( 2 ) page： 231 - 231 2004

Impact of graft length on surgical damage after intestinal transplantation in rats. Reviewed

Inoue S, Tahara K, Sakuma Y, Hori T, Uchida H, Hakamada Y, Murakami T, Takahashi M, Kawarasaki H, Hashizume K, Kaneko M, Kobayashi E

Transplant immunology Vol. 11 ( 2 ) page： 207-14 2003.4

Impact of graft length on surgical damage after intestinal transplantation in rats Reviewed

S Inoue, K Tahara, Y Sakuma, T Hori, H Uchida, Y Hakamada, T Murakami, M Takahashi, H Kawarasaki, K Hashizume, M Kaneko, E Kobayashi

TRANSPLANT IMMUNOLOGY Vol. 11 ( 2 ) page： 207 - 214 2003.4

Language：English Publishing type：Research paper (scientific journal) Publisher：ELSEVIER SCIENCE BV

Background: Intestinal grafts greatly affect nutrition and immunology in the host. The growth of the recipient and incidence of graft-versus-host disease depend on graft length. A larger graft may affect the host immune system, but little is known about how the length of the intestinal graft severely affects surgical intervention. We developed a cervical small bowel transplantation (SBT) rat model that minimized technical variations using a cuff method and studied the effects of graft length on surgical damage in SBT. Materials and methods: We transplanted a whole (70 cm) or partial (15 cm) intestine into a syngeneic rat combination of LEW (MHC haplotype: RT1(1)) to LEW and evaluated changes in perioperative hemodynamics and the endogenous endotoxin level. Natural killer (NK) cell activity in the peripheral blood and the immunologic response of the recipient spleen were also studied. Results: In the whole SBT model, body weight loss was more severe than in the segmental SBT model; the rats in the former model often died, while all in the latter survived indefinitely. The systemic blood pressure markedly decreased in the whole SBT group immediately after reperfusion. The proliferative activity of splenic lymphocytes stimulated by concanavalin A was also more severely inhibited in the former model than in the latter postoperatively. NK cell activity in the whole SBT rats declined more severely than the segmental SBT rats 3 days postoperatively. Conclusion: The longer graft severely induced surgical intervention; and influenced host immunosuppression, resulting in the higher mortality in rats undergoing whole SBT. (C) 2003 Elsevier Science B.V. All rights reserved.

Web of Science

Increase of bile acid production by tacrolimus in the rat liver. Reviewed

Mizuta K, Kobayashi E, Uchida H, Hishikawa S, Kawarasaki H

Transplantation proceedings Vol. 35 ( 1 ) page： 437-8 2003.2

Increase of bile acid production by tacrolimus in the rat liver Reviewed

K Mizuta, E Kobayashi, H Uchida, S Hishikawa, H Kawarasaki

TRANSPLANTATION PROCEEDINGS Vol. 35 ( 1 ) page： 437 - 438 2003.2

V-026 ブタ部分小腸移植モデル : VCS クリップを用いた血管吻合法 Reviewed

吉野浩之, 山内仁, 井上成一朗, 田原和典, 内田広夫, 宇野武治, 水田耕一, 河原秀雄, 橋都浩平, 小林英司

日本小児外科学会雑誌 Vol. 39 ( 3 ) page： 241 - 241 2003

4. 極低出生体重児のC型食道閉鎖症に対する新しい治療法の試み(セッションIV 低出生体重児)(第19回日本小児外科学会秋季シンポジウム : 先天性食道閉鎖症) Reviewed

岩中督, 内田広夫, 川嶋寛, 西明, 工藤寿美, 佐竹亮介

日本小児外科学会雑誌 Vol. 39 ( 6 ) page： 738 - 739 2003

Short-course methotrexate and long-term acceptance of fully allogeneic rat cardiac grafts: a possible mechanism of tolerance. Reviewed

Sakuma Y, Xiu D, Uchida H, Hakamata Y, Takahashi M, Murakami T, Nagai H, Kobayashi E

Transplant immunology Vol. 10 ( 1 ) page： 49-54 2002.6

Short-course methotrexate and long-term acceptance of fully allogeneic rat cardiac grafts: a possible mechanism of tolerance Reviewed

Sakuma Y, Xiu D, Uchida H, Hakamata Y, Takahashi M, Murakami T, Nagai H, Kobayashi E

TRANSPLANT IMMUNOLOGY Vol. 10 ( 1 ) page： 49 - 54 2002.6

Combined cuff and suture technique for orthotopic whole intestinal transplantation in rats. Reviewed

Nakao A, Tahara K, Inoue S, Mizuta K, Takeichi T, Uchida H, Tanaka N, Kobayashi E

Microsurgery Vol. 22 ( 3 ) page： 85-90 2002

Chronotherapy of sublethal doses of methotrexate on rats allogeneic heart grafts Reviewed International journal

Xiu, D.R., Sakuma, Y., Nagai, H., To, H., Sugimoto, K., Fujimura, A., Uchida, H., Kobayashi, E.

Research Communications in Pharmacology and Toxicology Vol. 7 ( 1-2 ) page： 77 - 85 2002

Comparison of efficacy and toxicity between Sandimmune® and Neoral® in the cyclosporine-resistant rat allo-pancreas transplantation Reviewed International journal

Sakuma, Y., Nagai, H., Sugimoto, K.-I., Fujimura, A., Murakami, T., Uchida, H., Hakamata, Y., Takahashi, M., Kobayashi, E.

Research Communications in Pharmacology and Toxicology Vol. 7 ( 1-2 ) page： 86 - 94 2002

Blunt Abdominal Injury and Pediatric Trauma Score in Children Reviewed

Fujino Junko, Ishimaru Yuki, Yamamoto Hideki, Uchida Hiroo, Ikeda Hitoshi

Journal of the Japanese Society of Pediatric Surgeons Vol. 38 ( 6 ) page： 826 - 832 2002

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society of Pediatric Surgeons

Purpose : To investigate whether the Pediatric Trauma Score (PTS) correlates with the need for surgery in patients with blunt abdominal injury, a retrospective study was done. Methods : There were 39 injuries of solid organs (liver, spleen and kidneys) and 9 injuries of other organs (duodenum, jejunum and diaphragm). These 48 organ injuries in 42 patients were classified according to the classifications of each organ injury and PTS, treatment and outcome were reviewed. Results and Conclusion : Surgery was done to manage 5 out of the 39 solid organ injuries. PTSs in patients who needed surgery ranged from 1 to 10 (median, 7) and were significantly lower than those with nonoperative management, 4-12 (median, 11)(p=0.004). In the 9 injuries of other organs, PTSs were 4-12 (median, 12) in patients who needed surgery and were not significantly different from the scores 10-12 (median, 10) in patients who were treated nonoperatively. These results indicate that surgical procedures may be necessary in patients with injuries of the liver, the spleen and the kidneys whose PTSs are low. PTS may be important in triage in children with abdominal blunt trauma, although an organspecific grading system should be developed to diagnose the extent of the injury and determine the treatment approach.

DOI： 10.11164/jjsps.38.6_826

CiNii Books

Other Link： http://search.jamas.or.jp/link/ui/2008346366

Vascularized composite tissue transfers for open fractures with massive soft-tissue defects in the lower extremities Reviewed

Nakao, A., Tahara, K., Inoue, S., Mizuta, K., Takeichi, T., Uchida, H., Tanaka, N., Kobayashi, E.

Microsurgery Vol. 22 ( 4 ) page： 131 - 132 2002

A-16 新生児小腸を用いた移植治療のための基礎的研究 Reviewed

内田広夫, 田原和典, 井上成一朗, 石丸由紀, 小林英司, 池田均

日本小児外科学会雑誌 Vol. 38 ( 3 ) page： 422 - 422 2002

Experimental small bowel transplantation using a newborn intestine in rats: IV. Effect of cold preservation on graft neovascularization. Reviewed

Uchida H, Tahara K, Takizawa T, Inose K, Yashiro T, Hashizume K, Ikeda H, Takahashi M, Kobayashi E

Journal of pediatric surgery Vol. 36 ( 12 ) page： 1805-10 2001.12

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