Faculty Profiles - UCHIDA Hiroo

Papers - UCHIDA Hiroo

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Multicenter, retrospective, comparative study of laparoscopic and open Kasai portoenterostomy in children with biliary atresia from Japanese high-volume centers Reviewed

Murase Naruhiko, Hinoki Akinari, Shirota Chiyoe, Tomita Hirofumi, Shimojima Naoki, Sasaki Hideyuki, Nio Masaki, Tahara Kazunori, Kanamori Yutaka, Shinkai Masato, Yamamoto Hirotoshi, Sugawara Yasuhiko, Hibi Taizo, Ishimaru Tetsuya, Kawashima Hiroshi, Koga Hiroyuki, Yamataka Atsuyuki, Uchida Hiroo

JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES Vol. 26 ( 1 ) page： 43 - 50 2019.1

Young pediatric surgeons without endoscopic surgical skill qualification safely perform advanced endoscopic surgery under the supervision of expert qualified surgeons. Reviewed Open Access

Ota K, Tainaka T, Hinoki A, Shirota C, Makita S, Yasui A, Nakagawa Y, Kato D, Maeda T, Ishii H, Uchida H

Surgical endoscopy 2025.3

Multi-dimensional consistency learning between 2D Swin U-Net and 3D U-Net for intestine segmentation from CT volume. Reviewed

An Q, Oda H, Hayashi Y, Kitasaka T, Uchida H, Hinoki A, Suzuki K, Takimoto A, Oda M, Mori K

International journal of computer assisted radiology and surgery 2025.2

Functional Outcome in Patients With Anorectal Malformation With Recto-prostatic or Recto-bulbar Urethral Fistula and Comparison Between Different Surgical Approaches: A Multi-center Study. Reviewed International journal

Carol Wing Yan Wong, Hiroyuki Koga, Koshiro Sugita, Daiki Kato, Annika Mutanen, Patrick Ho Yu Chung, Go Miyano, Toshio Harumatsu, Satoshi Ieiri, Yoichi Nakagawa, Hiroo Uchida, Mikko P Pakarinen, Kenneth Kak Yuen Wong

Journal of pediatric surgery Vol. 60 ( 2 ) page： 161652 - 161652 2025.2

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To analyze and compare the outcomes in patients with anorectal malformation with rectoprostatic and rectourethral fistula between laparoscopic-assisted anorectoplasty (LAARP) versus posterior sagittal anorectoplasty (PSARP). METHOD: We performed a retrospective review on all males with anorectal malformation (ARM) with recto-prostatic (ARM-RP) or recto-bulbar urethral fistula (ARM-RB) treated in five tertiary paediatric surgical centres in the past 25 years. Defecative function was assessed using the Krickenbeck classification and Kelly's score. Functional outcomes between patients with LAARP and PSARP were compared. RESULTS: There were a total of 136 males with ARM-RP and ARM-RB for analysis, among which 73 (53.7%) had ARM-RP and 63 (46.3%) had ARM-RB. The median age of the patients was 9.4 years (range 0.8-24.7 years) and the median age at operation was 0.4 years (0 day-3.1 years). 57 (41.9%) and 79 patients (58.1%) underwent PSARP and LAARP respectively. 34 patients (25%) had VACTERL association. 111 (81.6%) and 103 patients (75.7%) had sacral and spinal cord anomalies respectively. 19 patients (13.9%) eventually required Malone's Antegrade Continence Enema (MACE). For the comparison between PSARP and LAARP, no difference in Kelly scores (4.58 ± 1.63 versus 4.67 ± 1.36) was identified (p = 0.79). Logistic regression for voluntary bowel movement showed that VACTER association (p = 0.02) and fistula location (p = 0.01) were significant prognostic factors, whereas the operation approach (PSARP or LAARP) was not (p = 0.65). CONCLUSION: VACTERL association and fistula location were significant prognostic factors for voluntary bowel movement, and there appeared to be no significant difference in functional outcome between PSARP and LAARP. LEVEL OF EVIDENCE: IV.

DOI： 10.1016/j.jpedsurg.2024.07.037

PubMed

Evaluation of the risk factors for postoperative pectus excavatum and scoliosis in cystic lung disease. Reviewed

Takahisa T, Chiyoe S, Wataru S, Satoshi M, Hizuru A, Yoko K, Akihiro Y, Daiki K, Takuya M, Yousuke G, Hiroki I, Kazuki O, Akinari H, Hiroo U

Pediatric surgery international Vol. 41 ( 1 ) page： 62 2025.1

How many cases do young pediatric surgeons need to experience to achieve autonomy in performing pediatric endoscopic surgery? A nationwide survey to establish an ideal curriculum for pediatric endoscopic surgery in Japan. Reviewed International journal

Masakazu Murakami, Yo Kurashima, Katsuhiro Ogawa, Shinichiro Yokoyama, Satoshi Obata, Go Miyano, Tetsuya Ishimaru, Hiroshi Kawashima, Hiroo Uchida, Tatsuro Tajiri, Atsuyuki Yamataka, Hiroomi Okuyama, Satoshi Ieiri

Pediatric surgery international Vol. 41 ( 1 ) page： 54 - 54 2024.12

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: To ensure the safe prevalence of pediatric endoscopic surgery in Japan, a training curriculum should be established. In addition, the number of pediatric surgical cases is decreasing due to the decreasing birth rate in Japan, and it is necessary to clarify the number of surgical cases required for young pediatric surgeons to achieve autonomy in pediatric endoscopic surgery. METHODS: An online nationwide survey was conducted among young pediatric surgeons with 3-15 years of clinical experience in Japan. We assessed training experience, opinions concerning the ideal training curriculum, and the correlation between surgical experience and the level of autonomy for pediatric endoscopic surgeries. RESULTS: One hundred seventy participants responded to the survey (response rate: 35.2%). Only 18% answered that their training facility had a regular educational off-the-job training program. Ninety percent of respondents answered that an educational curriculum for pediatric endoscopic surgery was necessary. It took 11-20 cases to achieve autonomy in laparoscopic appendectomy and laparoscopic inguinal hernia repair. CONCLUSION: This survey revealed that off-the-job training programs were insufficient. The results of this study are expected to aid in the establishment of an effective curriculum for pediatric endoscopic surgery in the era of declining birth rates.

DOI： 10.1007/s00383-024-05958-9

Web of Science

PubMed

Safety and feasibility of robot-assisted surgery for pediatric patients weighing ≤ 10 kg with congenital biliary dilatation Reviewed

Hiroo UCHIDA

Journal of Robotic Surgery Vol. 19 ( 1 ) page： 34 2024.12

Characteristics and outcomes of minimally invasive surgery for congenital biliary dilatation in children aged <6 years: Comparison between children and adults Reviewed

Hiroo UCHIDA

Journal of Hepato-biliary-pancreatic Sciences Vol. 31 ( 12 ) page： 876 - 885 2024.12

Usefulness of lateral-anteroposterior dimeter ratio in patients with tracheomalacia associated with esophageal atresia Reviewed

Hiroo UCHIDA

Pediatric Surgery International Vol. 40 ( 1 ) page： 282 2024.10

Nationwide questionnaire survey on pediatric pancreatic tumors in Japan Reviewed

Hiroo UCHIDA

World Journal of Gastrointestinal Oncology Vol. 16 ( 10 ) page： 4166 - 4176 2024.10

Portal vein hypoplasia is present in patients with biliary atresia at the time of diagnosis Reviewed

Hiroo UCHIDA

Journal of Pediatric Gastroenterology and Nutrition Vol. 79 ( 4 ) page： 818 - 825 2024.10

First pediatric pelvic surgery with the Senhance® robotic surgical system: A case series Reviewed

Daiki Kato, Hiroo Uchida, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Hizuru Amano, Miwa Satomi, Akihiro Yasui, Yoichi Nakagawa, Takuya Maeda, Hiroki Ishii, Kazuki Ota, Naoki Nagata, Akinari Hinoki

Asian Journal of Endoscopic Surgery Vol. 17 ( 4 ) page： e13379 2024.10

特集必携小児外科レジデントマニュアル2 手術器具 Reviewed

田井中貴久, 城田千代栄, 牧田智, 天野日出, 檜顕成, 内田広夫

小児外科 Vol. 56 ( 9 ) page： 933 - 937 2024.9

Impact of Portal Flow on the Prognosis of Children With Congenital Portosystemic Shunt: A Multicentric Observation Study in Japan. Reviewed International journal

Hajime Uchida, Masato Shinkai, Hiroomi Okuyama, Takehisa Ueno, Mikihiro Inoue, Toshihiro Yasui, Eiso Hiyama, Sho Kurihara, Yasunaru Sakuma, Yukihiro Sanada, Akinobu Taketomi, Shohei Honda, Motoshi Wada, Ryo Ando, Jun Fujishiro, Mariko Yoshida, Yohei Yamada, Hiroo Uchida, Takahisa Tainaka, Mureo Kasahara

Journal of pediatric surgery Vol. 59 ( 9 ) page： 1791 - 1797 2024.9

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Although congenital portosystemic shunts (CPSSs) are increasingly being recognized, the optimal treatment strategies and natural prognosis remain unclear, as individual CPSSs show different phenotypes. METHODS: The medical records of 122 patients who were diagnosed with CPSSs at 15 participating hospitals in Japan between 2000 and 2019 were collected for a retrospective analysis based on the state of portal vein (PV) visualization on imaging. RESULTS: Among the 122 patients, 75 (61.5%) showed PV on imaging. The median age at the diagnosis was 5 months. The main complications related to CPSS were hyperammonemia (85.2%), liver masses (25.4%), hepatopulmonary shunts (13.9%), and pulmonary hypertension (11.5%). The prevalence of complications was significantly higher in patients without PV visualization than in those with PV visualization (P < 0.001). Overall, 91 patients (74.6%) received treatment, including shunt closure by surgery or interventional radiology (n = 82) and liver transplantation (LT) or liver resection (n = 9). Over the past 20 years, there has been a decrease in the number of patients undergoing LT. Although most patients showed improvement or reduced progression of symptoms, liver masses and pulmonary hypertension were less likely to improve after shunt closure. Complications related to shunt closure were more likely to occur in patients without PV visualization (P = 0.001). In 25 patients (20.5%) without treatment, those without PV visualization were significantly more likely to develop complications related to CPSS than those with PV visualization (P = 0.011). CONCLUSION: Patients without PV visualization develop CPSS-related complications and, early treatment using prophylactic approaches should be considered, even if they are asymptomatic. LEVEL OF EVIDENCE: Level III.

DOI： 10.1016/j.jpedsurg.2024.05.008

PubMed

Eicosapentaenoic acid administration ameliorates the progression of liver fibrosis after laparoscopic Kasai portoenterostomy Reviewed

Hiroo UCHIDA

Pediatric Surgery International Vol. 40 ( 1 ) page： 239 2024.8

特集再手術の戦略と実際胆道閉鎖症 Reviewed

城田千代栄, 田井中貴久, 牧田智, 加藤大幾, 前田拓也, 里見美和, 石井宏樹, 太田和樹, 檜顕成, 内田広夫

小児外科 Vol. 56 ( 7 ) page： 701 - 703 2024.7

特集再手術の戦略と実際先天性横隔膜ヘルニア再発に対する手術アプローチ Reviewed

合田陽祐, 内田広夫, 横田一樹, 城田千代栄, 田井中貴久, 住田亙, 牧田智, 里見美和, 安井昭洋, 加藤大幾, 前田拓也, 石井宏樹, 太田和樹, 檜顕成

小児外科 Vol. 56 ( 7 ) page： 682 - 685 2024.7

Cholestasis after Kasai operation predicts portal hypertension in native liver survivors of biliary atresia: a multicenter study. Reviewed International journal

Patrick Ho Yu Chung, Toshio Harumatsu, Yoichi Nakagawa, Koichi Tsuboi, Edwin Kin Wai Chan, Michael Wai Yip Leung, Fanny Yeung, Mitsuru Muto, Takafumi Kawano, Hizuru Amano, Chiyoe Shirota, Hiroki Nakamura, Hiroyuki Koga, Go Miyano, Atsuyuki Yamataka, Satoshi Ieiri, Hiroo Uchida, Kenneth Kak Yuen Wong

Pediatric surgery international Vol. 40 ( 1 ) page： 196 - 196 2024.7

Language：English Publishing type：Research paper (scientific journal)

PURPOSE: This study evaluated portal hypertension (PHT) and its predictors among native liver survivors (NLS) of biliary atresia (BA) after Kasai portoenterostomy (KPE). METHODS: This was a multicenter study using prospectively collected data. The subjects were patients who remained transplant-free for 5 years after KPE. Their status of PHT was evaluated and variables that predicted PHT were determined by regression analysis and receiver operating characteristic (ROC) curve. RESULTS: Six centers from East Asia participated in this study and 320 subjects with KPE between 1980 to 2018 were analyzed. The mean follow-up period was 10.6 ± 6.2 years. At the 5th year after KPE, PHT was found in 37.8% of the subjects (n = 121). Patients with KPE done before day 41 of life had the lowest percentage of PHT compared to operation at older age. At 12 months after KPE, PHT + ve subjects had a higher bilirubin level (27.1 ± 11.7 vs 12.3 ± 7.9 µmol/L, p = 0.000) and persistent jaundice conferred a higher risk for PHT (OR = 12.9 [9.2-15.4], p = 0.000). ROC analysis demonstrated that a bilirubin level above 38 µmol/L at 12 months after KPE predicted PHT development (sensitivity: 78%, specificity: 60%, AUROC: 0.75). CONCLUSIONS: In BA, early KPE protects against the development of PHT among NLSs. Patients with persistent cholestasis at one year after KPE are at a higher risk of this complication. They should receive a more vigilant follow-up. LEVEL OF EVIDENCE: Level III.

DOI： 10.1007/s00383-024-05775-0

PubMed

Bile lakes in patients with biliary atresia who presented with jaundice-free native liver survival indicating the risk of subsequent liver transplantation due to various factors. Reviewed International journal

Yousuke Gohda, Hiroo Uchida, Wataru Sumida, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Miwa Satomi, Akihiro Yasui, Daiki Kato, Takuya Maeda, Hiroki Ishii, Kazuki Ota, Yaohui Guo, Jiahui Liu, Akinari Hinoki

Pediatric surgery international Vol. 40 ( 1 ) page： 197 - 197 2024.7

Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)

PURPOSE: The prognostic factors of subsequent liver transplantation (LT) in patients with biliary atresia (BA) who presented with jaundice-free native liver survival were investigated. METHODS: This study retrospectively reviewed patients who underwent portoenterostomy (PE) for BA. Patients with jaundice-free native liver survival at 1 year postoperatively were divided into the autologous liver survivor and liver transplant recipient groups. Peri- and postoperative data were compared between the two groups. RESULTS: Among 97 patients with BA, 29 who received LT within 1 year after PE were excluded from the analysis. Further, 48 patients currently living with native liver and 20 who received LT after 1 year postoperatively were compared. Bile lake (BL) was the strongest risk factor of LT. The risk score was 2.38 ∗ B L s c o r e + 0.00466 ∗ T B A , and the area under the receiver operating characteristic curve was 0.83. Patients with BL and those without significantly differed in terms of the native liver survival rate. Patients with BL who presented with not only cholangitis but also gastrointestinal hemorrhage and hepatopulmonary syndrome received LT. CONCLUSION: BL can cause different pathologies. Moreover, it is an evident risk factor of subsequent LT in patients with BA who are living with native liver at 1 year after PE.

DOI： 10.1007/s00383-024-05786-x

PubMed

Developing an effective off-the-job training model and an automated evaluation system for thoracoscopic esophageal atresia surgery Reviewed

Akihiro Yasui, Yuichiro Hayashi, Akinari Hinoki, Hizuru Amano, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Satoshi Makita, Yoko Kano, Aitaro Takimoto, Yoichi Nakagawa, Maeda Takuya, Daiki Kato, Yousuke Gohda, Jiahui Liu, Yaohui Guo, Kensaku Mori, Hiroo Uchida

Journal of Pediatric Surgery 2024.7

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