Faculty Profiles - NISHIDA, Yoshihiro

Papers - NISHIDA, Yoshihiro

Division display 201 - 220 of about 708 ／ All the affair displays >>

Sarcopenia and physical function are associated with inflammation and arteriosclerosis in community-dwelling people: The Yakumo study Reviewed

Hida Tetsuro, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Muramoto Akio, Ito Kenyu, Ishikawa Yoshimoto, Tsushima Mikito, Nishida Yoshihiro, Ishiguro Naoki, Hasegawa Yukiharu

Modern rheumatology Vol. 28 ( 2 ) page： 345 - 350 2018.3

Effects of a self-assembling peptide as a scaffold on bone formation in a defect Reviewed Open Access

Ando Kei, Imagama Shiro, Kobayashi Kazuyoshi, Ito Kenyu, Tsushima Mikito, Morozumi Masayoshi, Tanaka Satoshi, Machino Masaaki, Ota Kyotaro, Nishida Koji, Nishida Yoshihiro, Ishiguro Naoki

PLOS ONE Vol. 13 ( 1 ) page： e0190833 2018.1

Efficacy of Conical Laminoplasty After Thoracic Laminectomy. Reviewed

Kobayashi K, Imagama S, Ando K, Nishida Y, Ishiguro N

Clinical spine surgery Vol. 31 ( 4 ) page： 156 - 161 2018

Self-efficacy is an independent predictor for postoperative six-minute walk distance after elective open repair of abdominal aortic aneurysm Reviewed Open Access

Hayashi Kazuhiro, Kobayashi Kiyonori, Shimizu Miho, Tsuchikawa Yohei, Kodama Akio, Komori Kimihiro, Nishida Yoshihiro

Disability and rehabilitation Vol. 40 ( 10 ) page： 1114 - 1118 2018

Post-operative delayed ambulation after thymectomy is associated withpre-operative six-minute walk distance. Reviewed Open Access

Hayashi K, Fukumoto K, Yokoi K, Nagaya M, Inoue T, Ito S, Nakajima H, Hattori K, Kadono I, Nishida Y

Disability and rehabilitation Vol. 40 ( 16 ) page： 1900 - 1905 2018

Impact of variation in physical activity after total joint replacement Reviewed Open Access

Hayashi, K; Kako, M; Suzuki, K; Takagi, Y; Terai, C; Yasuda, S; Kadono, I; Seki, T; Hiraiwa, H; Ushida, T; Nishida, Y

JOURNAL OF PAIN RESEARCH Vol. 11 page： 2399 - 2406 2018

Language：English Publishing type：Research paper (scientific journal) Publisher：Journal of Pain Research

Purpose: Patients who undergo total knee arthroplasty (TKA) or total hip arthroplasty (THA) often develop postoperative pain. Exercise approaches are recommended postoperatively; however, the impact of excessive variation in physical activity is unclear. The purpose of the present preliminary study was to investigate the impact of excessive variation in physical activity using the accelerometer in the early period after TKA or THA. Patients and methods: Seventy-two patients were enrolled in the study. Forty patients underwent initial TKA, and 32 initial THA. Physical activity was measured for 8 days from postoperative day 3 to 10. Patients with substantial correlation between physical activity and postoperative day were classified as the “good-pacing” group. Patients with no correlation between them were classified as the “poor-pacing” group. They were also evaluated using a pain visual analog scale (VAS), pain catastrophizing scale, and hospital anxiety and depression scale. Results: The average age was 68 years, and 59 patients (82%) were women. The average maximum number of steps per day was 2,181. There were 45 patients with good pacing and 27 with poor pacing. The poor-pacing group showed significantly lower maximum number of steps per day, higher postoperative average VAS score, higher postoperative worst VAS score, and longer duration of postoperative hospital stay than the good-pacing group. Conclusion: Patients with excessive variation in physical activity showed severe postoperative pain and prolonged postoperative hospital stay. The postoperative variation in physical activity could be an outcome for improvement in patients after lower-limb arthroplasty.

DOI： 10.2147/JPR.S178853

Posterior fusion of the occipital axis in children with upper cervical disorder using both C2 pedicle and laminar screws (C2 hybrid screws) Reviewed Open Access

Ito K., Imagama S., Ando K., Kobayashi K., Tsushima M., Matsumoto A., Morozumi M., Tanaka S., Machino M., Nishida Y., Ishiguro N.

Spine Surgery and Related Research Vol. 2 ( 1 ) page： 82 - 85 2018

Language：English Publishing type：Research paper (scientific journal) Publisher：Spine Surgery and Related Research

Introduction: An occipital-cervical surgery for children is challenging for surgeons because of the immature bone quality, extensive anatomical variability, and small osseous structures. Furthermore, occipital-C2 fusion in children results in great stress on the C2 screws. We report a technique that uses both C2 pedicle and bilateral lateral mass screws (C2 hybrid screws) in children with an upper cervical disorder to preserve motion segment and secure strength in those who require occipital-cervical fusion. Case Report: Case 1 was that of a 5-year-old girl with Down syndrome who had atlantoaxial dislocation and os odontoideum. Owing to the C1 hypoplasia, the posterior arch was fractured by the C1 lateral mass screw. Therefore, O-C2 fusion was performed. C2 bilateral lamina screws were added along with the C2 bilateral pedicle screws for reinforcement. Case 2 was that of an 8-year-old boy who presented with torticollis and neck pain. The patient was diagnosed as having atlantoaxial rotatory fixation. The right vertebral artery was obstructed, and the left vertebral artery was dominant. The C1 posterior arch was bifid and assimilated with the occipital bone. C2 bilateral lamina screws were added with the right C2 pedicle screw for reinforcement. Both cases attained bone union after O-C2 fusion surgery using hybrid screws. Conclusions: The use of C2 hybrid screws with both C2 pedicle and bilateral lateral mass screws can preserve mobile segments in the fusion area in young children who require occipital-cervical fixation.

DOI： 10.22603/ssrr.2016-0018

Open Access

Scopus

Analysis of falls that caused serious events in hospitalized patients Reviewed

Kobayashi Kazuyoshi, Imagama Shiro, Ando Kei, Inagaki Yuko, Suzuki Yusuke, Nishida Yoshihiro, Nagao Yoshimasa, Ishiguro Naoki

GERIATRICS & GERONTOLOGY INTERNATIONAL Vol. 17 ( 12 ) page： 2403 - 2406 2017.12

Independent association of joint space narrowing, cyst formation and health-related quality of life of patients with hip osteoarthritis in Japan Reviewed

Takegami Yasuhiko, Seki Taisuke, Higuchi Yoshitoshi, Komatsu Daigo, Nishida Yoshihiro, Ishiguro Naoki

JOURNAL OF ORTHOPAEDIC SCIENCE Vol. 22 ( 6 ) page： 1096 - 1101 2017.11

Preoperative Six-Minute Walk Distance and Desaturation in Patients with Malignant Pleural Mesothelioma Reviewed

Nagaya, M; Ito, S; Fukui, T; Inoue, T; Mizuno, Y; Kawaguchi, K; Nakamura, S; Nishida, Y; Hasegawa, Y; Yokoi, K

JOURNAL OF THORACIC ONCOLOGY Vol. 12 ( 11 ) page： S2308 - S2308 2017.11

Clinical and Radiographical Differences Between Thoracic Idiopathic Spinal Cord Herniation and Spinal Arachnoid Cyst Reviewed

Nakashima Hiroaki, Imagama Shiro, Yagi Hideki, Kato Fumihiko, Kanemura Tokumi, Sato Koji, Kawakami Noriaki, Kamiya Mitsuhiro, Yoshihara Hisatake, Ito Kenyu, Matsuyama Yukihiro, Nishida Yoshihiro, Ishiguro Naoki

SPINE Vol. 42 ( 16 ) page： E963 - E968 2017.8

The poor quality and reliability of information on periacetabular osteotomy on the internet in Japan Reviewed Open Access

Takegami Yasuhiko, Seki Taisuke, Amano Takafumi, Higuchi Yoshitoshi, Komatsu Daigo, Nishida Yoshihiro, Ishiguro Naoki

NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 79 ( 3 ) page： 375 - 385 2017.8

Conditional knockdown of hyaluronidase 2 in articular cartilage stimulates osteoarthritic progression in a mice model Reviewed Open Access

Higuchi, Y; Nishida, Y; Kozawa, E; Zhuo, LS; Arai, E; Hamada, S; Morita, D; Ikuta, K; Kimata, K; Ushida, T; Ishiguro, N

SCIENTIFIC REPORTS Vol. 7 ( 1 ) page： 7028 2017.8

Language：English Publishing type：Research paper (scientific journal) Publisher：Scientific Reports

The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated mice. Destabilization of the medial meniscus (DMM) model of Col2a promoter specific conditional Hyal2 knockout (Hyal -/- ) mice was established and examined. Age related and DMM induced alterations of articular cartilage of knee joint were evaluated with modified Mankin score and immunohistochemical staining of MMP-13, ADAMTS-5, KIAA11199, and biotinylated- hyaluronan binding protein staining in addition to histomorphometrical analyses. Effects of Hyal2 suppression were also analyzed using explant culture of an IL-1α induced articular cartilage degradation model. The amount and size of hyaluronan in articular cartilage were higher in Hyal2 -/- mice. Hyal2 -/- mice exhibited aggravated cartilage degradation in age-related and DMM induced mice. MMP-13 and ADAMTS-5 positive chondrocytes were significantly higher in Hyal2 -/- mice. Articular cartilage was more degraded in explant cultures obtained from Hyal2 -/- mice. Knockdown of Hyal2 in articular cartilage induced OA development and progression possibly mediated by an imbalance of HA metabolism. This suggests that Hyal2 knockdown exhibits mucopolysaccharidosis-like OA change in articular cartilage similar to Hyal1 knockdown.

DOI： 10.1038/s41598-017-07376-5

Heat-stimuli-enhanced osteogenesis using clinically available biomaterials Reviewed Open Access

Ota, T; Nishida, Y; Ikuta, K; Kato, R; Kozawa, E; Hamada, S; Sakai, T; Ishiguro, N

PLOS ONE Vol. 12 ( 7 ) page： e0181404 2017.7

Language：English Publishing type：Research paper (scientific journal) Publisher：Plos One

A recent study reported that heat stress stimulates osteogenesis in an in vivo rat model using alginate gel and magnetite cationic liposomes. However, for clinical use, the efficacy for promoting osteogenesis needs to be investigated using clinically approved materials, and preferably with animals larger than rats. The aim of this study was to evaluate multiple heat stimuli-triggered osteogenesis in rat tibial defect models using already clinically applicable materials (Resovist® and REGENOS®) and determine the efficacy also in the rabbit. Fifty-eight rats and 10 rabbits were divided into two groups, respectively, with or without hyperthermia treatment at 45C for 15 min. (hyperthermia; 20 rats once a week, 8 rats three times a week, 5 rabbits once a week, control; 30 rats and 5 rabbits). Micro-CT assessment at 4 weeks revealed that a significantly stimulated osteogenesis was observed in the once a week group of both rats and rabbits as compared to the control group (p = 0.018 and 0.036, respectively). In contrast, the three times a week group did not show enhanced osteogenesis. Histological examination and image analysis showed consistent results in which the area of mineralized bone formation in the once a week hyperthermia group was significantly increased compared with that in the control group at four weeks (rat; p = 0.026, rabbit; p = 0.031). Newly formed bone was observed in the grafted materials from the periphery toward the center, and more osteoclasts were found in the once a week group. Heat stress also induced enhanced alkaline phosphatase expression in cultured osteoblastic cells, MC3T3, in vitro (p = 0.03). On the other hand, heat stress had no obvious effects on chondrogenic differentiation using ATDC5 cells. Our study demonstrates that heat-stimuli with clinically applicable novel heating materials can promote significant osteogenesis, and may thus be a promising treatment option for diseases associated with bone defects.

DOI： 10.1371/journal.pone.0181404

Collaboration with an infection control team for patients with infection after spine surgery Reviewed

Kobayashi, K; Imagama, S; Kato, D; Ando, K; Hida, T; Ito, K; Tsushima, M; Matsumoto, A; Morozumi, M; Tanaka, S; Yagi, T; Nishida, Y; Ishiguro, N

AMERICAN JOURNAL OF INFECTION CONTROL Vol. 45 ( 7 ) page： 767 - 770 2017.7

Language：English Publishing type：Research paper (scientific journal) Publisher：American Journal of Infection Control

Background The risk of infection, including surgical site infection (SSI), after spine surgery has increased due to aging and more immunocompromised hosts. An infection control team (ICT) is responsible for management of health care-associated infections at our institution. Methods The study subjects were 40 patients (18 men and 22 women with an average age of 54 years) referred to the ICT after spine surgery since 2010. Pathogenic bacteria and treatment in these cases were reviewed. Results Collaboration with the ICT involved guidance on use of antibiotics for infection in 30 patients (16 SSI and 14 non-SSI) and a search for the infection focus for fever of unknown origin in 10 patients (7 patients were found to have urinary tract infections and 2 patients were found to have pneumonia). The detection rate of causative bacteria in ICT consultation was 88% (35 out of 40 patients). SSI patients with instrumentation involved had a significantly higher rate of methicillin-resistant Staphylococcus aureus infection compared with those without instrumentation (42% vs 13%; P <.05). Discussion All cases of SSI with instrumentation involved were cured by ICT support without removal of instrumentation. Early assistance from the ICT was important for prevention of worsening of methicillin-resistant S aureus infection. Conclusions Collaboration with the ICT was helpful for detection of pathogenic bacteria and allowed appropriate use of antibiotics at an early stage.

DOI： 10.1016/j.ajic.2017.01.013

Web of Science

Scopus

PubMed

Characteristics of Residual Symptoms After Laminoplasty in Diabetic Patients With Cervical Spondylotic Myelopathy Reviewed Open Access

Machino Masaaki, Imagama Shiro, Ando Kei, Kobayashi Kazuyoshi, Hida Tetsuro, Ito Kenyu, Tsushima Mikito, Matsumoto Akiyuki, Tanaka Satoshi, Morozumi Masayoshi, Ito Keigo, Kato Fumihiko, Nishida Yoshihiro, Ishiguro Naoki

SPINE Vol. 42 ( 12 ) page： E708 - E715 2017.6

Analysis of Factors for Predicting Survival in Soft-tissue Sarcoma with Metastatic Disease at Initial Presentation. Reviewed Open Access

Nakamura T, Katagiri H, Shido Y, Hamada S, Yamada K, Nagano A, Yamada S, Tsukushi S, Ishimura D, Matsumine A, Sudo A, Nishida Y.

Anticancer Res. Vol. 37 ( 6 ) page： 3137 - 3141 2017.6

Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report Reviewed

Ando, K; Imagama, S; Kobayashi, K; Nishida, Y; Ishiguro, N

EUROPEAN SPINE JOURNAL Vol. 26 ( 1 ) page： S111 - S116 2017.5

Language：English Publishing type：Research paper (scientific journal) Publisher：European Spine Journal

Objective We present such a case of aggressive osteoblastoma of cervical spine. We describe its complicated clinical progression, hoping to shed light on the surgical strategy of this complex tumor. Methods We present such a case of aggressive osteoblastoma involving the C6–7 vertebrae. A 25-year-old man was diagnosed as aggressive osteoblastoma of the cervical spine. The lesion encroached upon the radicular foramina and was located adjacent to the canal of the vertebral artery. Preoperative embolization was performed to reduce intraoperative bleeding and to prevent intraoperative injury of the vertebral artery. Results A pathologic examination showed osteoblasts suggestive of osteoblastoma. At 2-year follow-up, bony union was achieved, and there was no evidence of recurrence on a CT scan. Conclusion En bloc total resection for highly vascular osteoblastoma is ideal, but this case shows that piecemeal total resection following preoperative embolization is a surgical option for highly expansive osteoblastoma.

DOI： 10.1007/s00586-016-4904-7

Web of Science

Scopus

PubMed

Associations among pain catastrophizing, muscle strength, and physical performance after total knee and hip arthroplasty Reviewed Open Access

Hayashi K., Kako M., Suzuki K., Hattori K., Fukuyasu S., Sato K., Kadono I., Sakai T., Hasegawa Y., Nishida Y.

World Journal of Orthopedics Vol. 8 ( 4 ) page： 336 - 341 2017.4

Language：English Publishing type：Research paper (scientific journal) Publisher：World Journal of Orthopedics

AIM To investigate whether reductions in pain catastrophizing associated with physical performance in the early period after total knee arthroplasty (TKA) or total hip arthroplasty (THA). METHODS The study group of 46 participants underwent TKA or THA. The participants were evaluated within 7 d before the operation and at 14 d afterwards. Physical performance was measured by the Timed Up and Go (TUG) test, and 10-m gait time was measured at comfortable and maximum speeds. They rated their knee or hip pain using a visual analog scale (VAS) for daily life activities. Psychological characteristics were measured by the Pain Catastrophizing Scale (PCS). Physical characteristics were measured by isometric muscle strength of knee extensors and hip abductors on the operated side. The variables of percent changes between pre- and postoperation were calculated by dividing post-operation score by pre-operation score. RESULTS Postoperative VAS and PCS were better than preoperative for both TKA and THA. Postoperative physical performance and muscle strength were poorer than preoperative for both TKA and THA. The percent change in physical performance showed no correlation with preoperative variables. In TKA patients, the percent change of PCS showed correlation with percent change of TUG (P = 0.016), 10-m gait time at comfortable speeds (P = 0.003), and 10-m gait time at maximum speeds (P = 0.042). The percent change of muscle strength showed partial correlation with physical performances. The percent change of VAS showed no correlation with physical performances. On the other hand, in THA patients, the percent change of hip abductor strength showed correlation with percent change of TUG (P = 0.047), 10-m gait time at comfortable speeds (P = 0.001), and 10-m gait time at maximum speeds (P = 0.021). The percent change of knee extensor strength showed partial correlation with physical performances. The percent change of VAS and PCS showed no correlation with physical performances. CONCLUSION Changes in pain catastrophizing significantly associated with changes in physical performance in the early period after TKA. It contributes to future postoperative rehabilitation of arthroplasty.

DOI： 10.5312/wjo.v8.i4.336

Open Access

Scopus

PubMed

Comparative Study of Surgical Treatment and Nonsurgical Follow Up for Thoracic Ossification of the Posterior Longitudinal Ligament: Radiological and Clinical Evaluation Reviewed

Ando, K; Imagama, S; Kobayashi, K; Hida, T; Ito, K; Tsushima, M; Ishikawa, Y; Matsumoto, A; Nishida, Y; Ishiguro, N

SPINE Vol. 42 ( 6 ) page： 407 - 410 2017.3

Language：English Publishing type：Research paper (scientific journal) Publisher：Spine

Study Design. A prospective clinical study of factors related to myelopathy deterioration caused by thoracic myelopathy because of ossification of the posterior longitudinal ligament (T-OPLL). Objective. The objective of the study was to investigate factors related to myelopathy deterioration caused by T-OPLL. Summary of Background Data. Detailed analyses of factors related to myelopathy deterioration caused by T-OPLL have not been reported. Methods. Twenty-two patients (group O) received observation therapy because of the absence of or mild myelopathy, which was defined as walking unaided or with support, and a Japanese Orthopedic Association (JOA) score above 7 points; and 24 patients (group S) were treated with posterior decompression and fusion with instrumentation. Age, sex, body mass index (BMI), presence of diabetes mellitus (DM), and JOA score were obtained for all patients. Radiologically, the T-OPLL level, number of T-OPLLs, canal diameter ratio (CDR), morphology, ossification of the ligamentum flavum (OLF), and cervical OPLL were examined on reconstructed CT, and the presence of hyperintense areas (HIAs) on T2-weighted sagittal MR images. Results. In total, the patients included 22 males and 24 females and had an age range from 18 to 80 years. Sex, DM, JOA score in each domain, OPLL location, OPLL number, CDR of OPLL, morphology, OLF, and cervical OPLL did not differ significantly between groups N and S. However, cases in group N had a significantly higher age, lower weight, lower BMI, lower discontinuous rate on sagittal CT, and a lower HIA rate on MRI. Postoperatively, discontinuous segments connected and became continuous across the disc space in all patients in group S without progression of OPLL thickness. Conclusion. Age, weight, BMI, discontinuity between rostral and caudal OPLL lesions, and occurrence of a high intensity area on MRI are likely to be associated with development of myelopathy.

DOI： 10.1097/BRS.0000000000001769

Web of Science

Scopus

PubMed

　 PREV - NEXT 　

<NISHIDA, Yoshihiro>

Papers - NISHIDA, Yoshihiro