研究者詳細 - 清水　裕彦

論文 - 清水　裕彦

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Small-angle characterization of multimetric variants related to Parkinson's disease of ubiquitin carboxyl-terminal hydrolase L1 in water by small-angle neutron scattering

Naito S., Mochizuki H., Yasuda T., Mizuno Y., Furusaka M., Ikeda S., Shimizu H.M., Adachi T., Suzuki J., Fujiwara S., Okada Y., Mshikawa K., Aoki S., Wada K.

Polymer Preprints Japan 55 巻 ( 1 ) 2006年10月

出版者・発行元：Polymer Preprints Japan

UCH-L1 is a neuro-specific multiple functional enzyme. To examine the relationship between PD and the configuration of UCH-L1 variants [wild-type, I93M (linked to familial PD), and SI8Y (linked to reduced risk of PD)], we examined their structures in dueterized water directly using small-angle neutron scattering. We demonstrate that these were all self-assembled dimers. The wild-type was a rotating ellipsoidal dimer although the crystal structure predicted from the UCH-L3 was globular. The globular form of the monomeric component deformed by the I93M mutation. Conversely, the SI8Y polymorphism promoted the globularity. The morphological structures of UCH-L1 variants and PD exhibit good pathological correlation.

Scopus

Design study of superconducting sextupole magnet using HTS coated conductor for neutron-focusing device

Tosaka, T; Koyanagi, K; Ono, M; Kuriyama, T; Watanabe, I; Tsuchiya, K; Suzuki, J; Adachi, T; Shimizu, HM

PHYSICA C-SUPERCONDUCTIVITY AND ITS APPLICATIONS 445 巻 ( 1-2 ) 頁： 1095 - 1098 2006年10月

出版者・発行元：Physica C Superconductivity and Its Applications

We performed a design study of sextupole magnet using high temperature superconducting (HTS) wires. The sextupole magnet is used as a focusing lens for neutron-focusing devices. A neutron-focusing device is desired to have a large aperture and a high magnetic field gradient of G, where G = 2B/r2, B is the magnetic field and r is a distance from the sextupole magnet axis. Superconducting magnets offer promising prospects to meet the demands of a neutron-focusing device. Recently NbTi coils of low temperature superconducting (LTS) have been developed for a sextupole magnet with a 46.8 mm aperture. The maximum magnetic field gradient G of this magnet is 9480 T/m2 at 4.2 K and 12,800 T/m2at 1.8 K. On the other hand, rapid progress on second generation HTS wire has been made in increasing the performance of critical current and in demonstrating a long length. The second generation HTS wire is referred to as coated conductor. It consists of tape-shaped base upon which a thin coating of superconductor, usually YBCO, is deposited or grown. This paper describes a design study of sextupole magnet using coated conductors. © 2006.

DOI： 10.1016/j.physc.2006.05.043

Web of Science

Scopus

Performance of a multi-anode photomultiplier employing a weak electrostatic focusing system (Hamamatsu R8900 series)

Kawasaki, Y; Bertaina, ME; Sakaki, N; Shimizu, HM; Inoue, N; Hasegawa, S; Ohtsu, I; Adachi, T; Ebisuzaki, T; Hirota, K; Ikeda, K; Kajino, F; Morishima, T; Nagano, M; Sato, M; Sawabe, T; Shibata, T; Shinohara, T; Takeda, M; Takizawa, Y; Uchihori, Y; Wada, Y

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 564 巻 ( 1 ) 頁： 378 - 394 2006年8月

出版者・発行元：Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment

We have developed and tested a new type of multi-anode photomultiplier: Hamamatsu R8900-03 series. The main feature of the R8900-03 series is a highly sensitive surface: ∼ 83 % of the physical area. In this paper we report on the results of measurements we performed to check several parameters of this new type of photomultiplier. R8900-03 photomultipliers are devices suitable for experiments where large collection area and uniform detection efficiency are essential characteristics. © 2006 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.nima.2006.03.010

Web of Science

Scopus

低速中性子光学 Open Access

清水裕彦

加速器 3 巻 ( 2 ) 頁： 128 - 136 2006年7月

Nb3Sn sextupole magnet for neutron beam focusing

Okamoto, K; Nakamura, K; Seki, Y; Ohno, M; Takao, T; Mitsuda, C; Ohuchi, N; Shintomi, T; Tsuchiya, K; Adachi, T; Shimizu, H; Oku, T; Suzuki, J; Kimura, S; Hanai, S; Urata, M; Watanabe, I

IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY 16 巻 ( 2 ) 頁： 362 - 365 2006年6月

出版者・発行元：IEEE Transactions on Applied Superconductivity

In order to obtain a high-intensity neutron beam for neutron scattering experiments, strong sextupole magnets with large apertures are useful as a focusing element. We have started the development of a Nb<inf>3</inf>Sn sextupole magnet for this purpose. The design field strength of the sextupole is 12780 T/m2 and the aperture of the coil is 46 mm in diameter. As a first step of the development, three model coils have been made in order to learn about Nb<inf>3</inf>Sn technology and to evaluate the fabrication techniques. Single-pole tests of these coils have been performed to assess the conductor stability and training behavior of the Nb<inf>3</inf>Sn coils. This paper describes the design of the magnet, the fabrication of the model coils and the results of single-pole tests. © 2006 IEEE.

DOI： 10.1109/TASC.2006.873329

Web of Science

Scopus

Terahertz imaging with a direct detector based on superconducting tunnel junctions

Ariyoshi, S; Otani, C; Dobroiu, A; Sato, H; Kawase, K; Shimizu, HM; Taino, T; Matsuo, H

APPLIED PHYSICS LETTERS 88 巻 ( 20 ) 2006年5月

出版者・発行元：Applied Physics Letters

We demonstrated terahertz imaging using a direct detector based on niobium superconducting tunnel junctions (STJs). The detector is composed of linearly distributed junctions placed on a superconducting microstrip line and is integrated on two wings of a log-periodic antenna. We succeeded nondestructive imaging for an integrated-circuit card and dry material using the detector around its sensitivity peak (∼0.66 THz). The dynamic range was measured to be higher than 4× 107 (76 dB). Thus, the STJ detector is applicable to high-sensitivity and high-speed terahertz imaging for various nondestructive inspection applications. © 2006 American Institute of Physics.

DOI： 10.1063/1.2204842

Web of Science

Scopus

A broadband terahertz detector using a superconducting tunnel junction

Taino, T; Nakano, R; Yoshimura, S; Myoren, H; Takada, S; Otani, C; Ariyoshi, S; Shibuya, T; Kawase, K; Sato, H; Shimizu, HM

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 559 巻 ( 2 ) 頁： 751 - 753 2006年4月

出版者・発行元：Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment

We have proposed and demonstrated a new broadband terahertz (THz) wave detector using a superconducting tunnel junction (STJ) fabricated on LiNbO<inf>3</inf>, LiTaO<inf>3</inf>, and sapphire substrates. These substrates have relatively high absorption efficiency for THz waves, and we have expected that incident THz waves from substrate side are absorbed and that generate many THz phonons which break Cooper pairs in the base superconductor electrode of the STJ. Using a frequency-tunable THz pulse source in 1-2 THz, we have confirmed that the current signal corresponding to the THz input was observed. In addition, we found two current components with different timescales for the first time. We interpret that the slow component corresponds to phonons absorbed with the substrate and that the fast one corresponds to the directly absorbed photons with the superconductor electrode of the STJs. © 2006 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.nima.2005.12.207

Web of Science

Scopus

Detection of α particles with a superconducting series-junction detector

Kurakado, M; Kirk, EC; Sato, H; Jerjen, I; Shiki, S; Shimizu, HM; Zehnder, A; Taniguchi, K

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 559 巻 ( 2 ) 頁： 480 - 482 2006年4月

出版者・発行元：Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment

Alpha particles were measured with a superconducting series-junction detector. The effective area and thickness of the detector are given by a circle of 0.5 mm in diameter and 500 μm Al<inf>2</inf>O<inf>3</inf>, respectively. The risetime of the charge-sensitive preamplifiers, i.e. charge collection time of the detector, was about 5 μs. An energy resolution of 0.35% was obtained for 5.5 MeV α particles. © 2006 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.nima.2005.12.080

Web of Science

Scopus

Development of a low energy particle detector using a superconducting transition edge sensor

Ohno, M; Sato, H; Ikeda, T; Shimizu, HM

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 559 巻 ( 2 ) 頁： 573 - 575 2006年4月

出版者・発行元：Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment

It is possible for a superconductive transition edge sensor (TES) to detect directly the low energy proton generated in the neutron beta decay. The precision measurement of the proton spectrum is important to test the prediction of the Standard Model of electroweak interaction. Therefore, we are developing a TES microcalorimeter with a large effective area for a proton detector. Our first TES device consists of four-pixels using a Ti/Au bilayer. All pixels are parallel biased and X-rays from a 55Fe source are detected successfully. © 2005 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.nima.2005.12.058

Web of Science

Scopus

Refraction as a means of encoding wavelength for neutron reflectometry

Cubitt, R; Shimizu, HM; Ikeda, K; Torikai, N

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 558 巻 ( 2 ) 頁： 547 - 550 2006年3月

出版者・発行元：Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment

Neutron reflectometry is a well-established technique used to analyze the structure of interfaces as a function of depth normal to the surface. On a continuous source of neutrons, such as a reactor, the measurement can be done at a fixed incident angle and a white beam with the neutron wavelength encoded by the use of choppers to measure the time of flight. Although providing a certain flexibility in wavelength resolution, choppers have low transmission. This paper explores the possibility of using refraction to encode neutron wavelength opening the possibility of reactor sources to use almost the full-time-averaged neutron flux available and hence, increase the performance of neutron reflectometers by orders of magnitude. © 2005 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.nima.2005.12.045

Web of Science

Scopus

Characterization of multimetric variants of ubiquitin carboxyl-terminal hydrolase L1 in water by small-angle neutron scattering

Naito, S; Mochizuki, H; Yasuda, T; Mizuno, Y; Furusaka, M; Ikeda, S; Adachi, T; Shimizu, HM; Suzuki, J; Fujiwara, S; Okada, T; Nishikawa, K; Aoki, S; Wada, K

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 339 巻 ( 2 ) 頁： 717 - 725 2006年1月

出版者・発行元：Biochemical and Biophysical Research Communications

Here, we illustrated that the morphological structures of ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) variants and Parkinson's disease (PD) exhibit good pathological correlation by a small-angle neutron scattering (SANS). UCH-L1 is a neuro-specific multiple functional enzyme, deubiquitinating, ubiquityl ligase, and also involved in stabilization of mono-ubiquitin. To examine the relationship between multiple functions of UCH-L1 and the configuration of its variants [wild-type, I93M (linked to familial Parkinson's disease), and S18Y (linked to reduced risk of Parkinson's disease)], in this report, we proposed that these were all self-assembled dimers by an application of a rotating ellipsoidal model; the configurations of these dimers were quite different. The wild-type was a rotating ellipsoidal. The globular form of the monomeric component deformed by the I93M mutation. Conversely, the S18Y polymorphism promoted the globularity. Thus, the multiple functional balance is closely linked to the intermolecular interactions between the UCH-L1 monomer and the final dimeric configuration. © 2005 Elsevier Inc. All rights reserved.

DOI： 10.1016/j.bbrc.2005.11.066

山口達, 春名潤, 金子純一, 須佐憲三, 三浦誠司, 八木康洋, 川村宗範, 奥隆之, 藤田文行, 本間彰, 石橋浩之, 澤村晃子, 古坂道弘, 清水裕彦, 鬼柳善明

日本原子力学会　年会・大会予稿集 2006s 巻 ( 0 ) 頁： 64 - 64 2006年

出版者・発行元：一般社団法人日本原子力学会

中性子用薄膜シンチレータへの応用を念頭に置き、ガドリニウムオルソシリケート(Gd2SiO5)、ガドリニウムパイロシリケート(Gd2Si2O7)を合成し、発光特性評価ならびに構造解析を行った。Gd2Si2O7にCeを10%ドープしたところ結晶がF構造をとり、高い発光強度を示した。

DOI： 10.11561/aesj.2006s.0.64.0

CiNii Research

Gd系薄膜シンチレータの開発(2)

土田昇平, 春名潤, 金子純一, 須佐憲三, 三浦誠司, 奥隆之, 藤田文行, 本間彰, 澤村晃子, 古坂道弘, 清水裕彦, 鬼柳善明

日本原子力学会　年会・大会予稿集 2006s 巻 ( 0 ) 頁： 65 - 65 2006年

出版者・発行元：一般社団法人日本原子力学会

中性子散乱実験等への適用を目指し、厚さ30μm程度のGd系薄膜シンチレータの開発を目指している。本研究においてはGSO系粉体シンチレータを焼結することで薄膜化を試みた。焼結によりGSO(Gd2SiO5)は発光能力を失ったもののGPS(Gd2Si2O7)は発光能力を維持し、非常に丈夫で透明度の高い薄膜シンチレータの製作に成功した。

DOI： 10.11561/aesj.2006s.0.65.0

CiNii Research

20aSF-4 4重極磁石を用いた高偏極中性子ビームの生成と基礎物理への応用(20aSF 対称性・基礎物理・核モーメント,実験核物理領域) Open Access

山田悟, 奥隆之, 三島賢二, 佐藤広海, 広田克也, 森嶋隆裕, 大野雅史, 篠原武尚, 鈴木淳市, 清水裕彦

日本物理学会講演概要集 61.2.1 巻 ( 0 ) 頁： 29 2006年

30aWD-5 超伝導転移端温度計(TES)を用いた低エネルギー粒子線検出器の開発(3)(30aWD 対称性・基礎物理,実験核物理領域) Open Access

大野雅史, 佐藤広海, 森嶋隆裕, 三島賢二, 池田時浩, 山田悟, 清水裕彦

日本物理学会講演概要集 61.1.1 巻 ( 0 ) 頁： 73 2006年

30pXD-7 多重積層放物面型熱中性子収束光学素子の集光特性(30pXD X線・粒子線(中性子・粒子線),領域10(誘電体,格子欠陥,X線・粒子線,フォノン物性)) Open Access

池田一昭, 篠原武尚, 広田克也, 佐藤広海, 清水裕彦, 日野正裕, 奥隆之, 鈴木淳市, 曽山和彦, 大山研司, 平賀晴弘

日本物理学会講演概要集 61.1.4 巻 ( 0 ) 頁： 965 2006年

30pXD-6 Aharonov-Casher効果精密測定のためのJamin型多層膜冷中性子干渉計の開発(30pXD X線・粒子線(中性子・粒子線),領域10(誘電体,格子欠陥,X線・粒子線,フォノン物性)) Open Access

関義親, 舟橋春彦, 竹谷薫, 日野正裕, 北口雅暁, 大竹淑恵, 清水裕彦

日本物理学会講演概要集 61.1.4 巻 ( 0 ) 頁： 965 2006年

30pXD-5 磁場勾配を用いた中性子スピン偏極デバイスの開発(30pXD X線・粒子線(中性子・粒子線),領域10(誘電体,格子欠陥,X線・粒子線,フォノン物性)) Open Access

奥隆之, 山田悟, 鈴木淳市, 三島賢二, 篠原武尚, 池田一昭, 広田克也, 佐藤広海, 清水裕彦

日本物理学会講演概要集 61.1.4 巻 ( 0 ) 頁： 965 2006年

Development of Mach-Zehnder interferometer and "Coherent beam steering" technique for cold neutrons

Taketani K., Funahashi H., Seki Y., Hino M., Kitaguchi M., Maruyama R., Otake Y., Shimizu H.M.

Proceedings of the 8th International Symposium on Foundations of Quantum Mechanics in the Light of New Technology Isqm Tokyo 2005 頁： 282 - 285 2006年

出版者・発行元：Proceedings of the 8th International Symposium on Foundations of Quantum Mechanics in the Light of New Technology Isqm Tokyo 2005

We are developing multilayer interferometer of Mach-Zehnder type for cold neutrons. To fulfill severe requirements for aligning the four mirrors, we utilize six solid-etalon-plates and a high precision flat base plate. New devices making use of magnetic birefringence have been developed and demonstrated to be useful for fine adjustment of superposition between the two paths labeled with neutron spin.

DOI： 10.1142/9789812773210_0060

Scopus

Polyimide Buffer Layer for STJ Photon Detector Open Access

Taino T., Yoshida M., Narisawa M., Myoren H., Kikuchi K., Nakagawa H., Aoyagi M., Sato H., Shimizu H. M., Takada S.

7TH EUROPEAN CONFERENCE ON APPLIED SUPERCONDUCTIVITY (EUCAS'05) 43 巻頁： 1319 - 1321 2006年

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