Papers - TOYOKUNI Shinya
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Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Invited Reviewed
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD.
Cell Vol. 171 ( 2 ) page: 273-285 2017.10
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The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis-resistance to non-thermal plasma therapy. Invited Reviewed
Toyokuni S.
Pathol Int. Vol. 66 ( 5 ) page: 245-259 2016.5
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Phlebotomy as a preventive measure for crocidolite-induced mesothelioma in male rats. Reviewed
Ohara Y, Chew SH, Shibata T, Okazaki Y, Yamashita K, Toyokuni S.
Cancer Science 2017.11
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Diameter and rigidity of multi-walled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis. Reviewed
Nagai H, Okazaki Y, Chew SH, Misawa N, Yamashita Y, Akatsuka S, Ishihara T, Yamashita K, Yoshikawa Y, Yasui H, Jiang L, Ohara H, Takahashi T, Ichihara G, Kostarelos K, Miyata Y, Shinohara H and Toyokuni S.
Proc. Natl. Acad. Sci. USA Vol. 108 page: E1330-1338 2011
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Iron overload signature in chrysotile-induced malignant mesothelioma. Reviewed
Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y, Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama N, Takahashi T and Toyokuni S.
J Pathol Vol. 228 page: 366-377 2012.8
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Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer. Reviewed
Akatsuka S, Yamashita Y, Ohara H, Liu YT, Izumiya M, Abe K, Ochiai M, Jiang L, Nagai H, Okazaki Y, Murakami H, Sekido Y, Arai E, Kanai Y, Hino O, Takahashi T, Nakagama H and Toyokuni S.
PLoS ONE Vol. 7 ( 8 ) page: e43403 2012.8
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Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma. Reviewed
Jiang L, Yamashita Y, Chew SH, AKatsuka S, Ukai S, Wang S, Nagai H, Okazaki Y, Takahashi T and Toyokuni S.
J Pathol Vol. 233 page: 502-414 2014
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Iron as Soul of Life on Earth Revisited: From Chemical Reaction, Ferroptosis to Therapeutics
Harigae Hideo, Hino Keisuke, Toyokuni Shinya
FREE RADICAL BIOLOGY AND MEDICINE Vol. 133 page: 1-2 2019.3
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Lunar life drives jawbone formation Reviewed International journal Open Access
Sato K., Kouyama N., Akatsuka S., Motooka Y., Wang Q., Hibi H., Toyokuni S.
Journal of Dental Sciences Vol. 20 ( 4 ) page: 2399 - 2406 2025.10
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Iron-catalyzed oxidative stress compromises cancer promotional effect of BRCA2 haploinsufficiency through mitochondria-targeted ferroptosis. Reviewed International journal Open Access
Maeda Y, Motooka Y, Akatsuka S, Tanaka H, Mashimo T, Toyokuni S
Redox biology Vol. 85 page: 103739 2025.9
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LRP2 is a potential molecular target for nonsyndromic pathological myopia Reviewed International journal Open Access
Delaunay, K; Picard, E; Lassiaz, P; Jonet, L; Cannaya, V; Ruiz-Moreno, JM; Kojima, K; Vorum, H; Honore, B; Medrano, JR; Cehofski, LJ; Pussard, E; Kozyraki, R; Torriglia, A; Cases, O; Behar-Cohen, F
JCI INSIGHT Vol. 10 ( 15 ) 2025.8
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Terrestrial iron sulfide minerals induce distinct regulation of intracellular redox homeostasis and iron assimilation. Reviewed International journal Open Access
Lyu Q, Kouketsu Y, Tazaki A, Kato M, Motooka Y, Toyokuni S
Ecotoxicology and environmental safety Vol. 298 page: 118327 2025.6
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Selective Killing of Human Breast Cancer Cells by Plasma-Treated L-Arginine Solution Reviewed International journal Open Access
Du, LY; Miron, C; Kondo, T; Kumagai, J; Mizuno, M; Toyokuni, S; Kajiyama, H; Hori, M; Tanaka, H
PLASMA PROCESSES AND POLYMERS Vol. 22 ( 4 ) 2025.4
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Selenoprotein-mediated redox regulation shapes the cell fate of HSCs and mature lineages. Reviewed International journal Open Access
Aoyama Y, Yamazaki H, Nishimura K, Nomura M, Shigehiro T, Suzuki T, Zang W, Tatara Y, Ito H, Hayashi Y, Koike Y, Fukumoto M, Tanaka A, Zhang Y, Saika W, Hasegawa C, Kasai S, Kong Y, Minakuchi Y, Itoh K, Yamamoto M, Toyokuni S, Toyoda A, Ikawa T, Takaori-Kondo A, Inoue D
Blood Vol. 145 ( 11 ) page: 1149 - 1163 2025.3
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Wavelength-dependency of the impact of light on proliferation and DNA damage of corneal cells<i> in</i><i> vitro</i> Reviewed International journal Open Access
Francon, A; Behar-Cohen, F; Torriglia, A
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY Vol. 264 2025.3
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Silicone oil, an intraocular surgical adjuvant, induces retinal ferroptosis. Reviewed International journal Open Access
Shimizu H, Tanaka H, Tazaki A, Yamada K, Suzumura A, Ota J, Ushio-Watanabe N, Zheng H, Kataoka K, Hara H, Nishikawa Y, Yasukawa T, Suzuma K, Terasaki H, Nishiguchi KM, Kato M, Toyokuni S, Kaneko H
Free radical biology & medicine Vol. 228 page: 33 - 43 2025.2
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Repeated exposure to low doses of light induces retinal damage in vivo in a wavelength-dependent manner Reviewed International journal Open Access
Françon, A; Jonet, L; Behar-Cohen, F; Torriglia, A
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY Vol. 290 2025.1
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Decoding the molecular enigma behind asbestos and fibrous nanomaterial-induced carcinogenesis International journal Open Access
Toyokuni Shinya, Kong Yingyi
Journal of Occupational Health Vol. 67 ( 1 ) page: n/a 2025.1
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BRCA1 haploinsufficiency impairs iron metabolism to promote chrysotile-induced mesothelioma via ferroptosis resistance Reviewed International journal
Luo, YG; Toyokuni, S
CANCER SCIENCE Vol. 116 page: 193 - 193 2025.1
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Complementary Interplay of Iron and Sulfur: Implications for Cellular Redox Regulation Reviewed International journal
Lyu, QY; Toyokuni, S; Kouketsu, Y
CANCER SCIENCE Vol. 116 page: 1388 - 1388 2025.1