論文 - 山中 宏二
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Neuroinflammation in motor neuron disease.
Komine O, Yamanaka K
Nagoya Journal of Medical Science 77 巻 ( 4 ) 頁： 537-549 2015年11月
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Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. 査読有り 国際共著
Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A
Neurobiology of Disease 86 巻 頁： 16-28 2015年11月
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Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity. 査読有り
Watanabe S, Hayakawa T, Wakasugi K, Yamanaka K
Cell Death and Disease 5 巻 頁： e1497 2014年10月
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SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system. 査読有り
Watanabe S, Ageta-Ishihara N, Nagatsu S, Takao K, Komine O, Endo F, Miyakawa T, Misawa H, Takahashi R, Kinoshita M, Yamanaka K
Molecular Brain 7 巻 ( 62 ) 2014年8月
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Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life. 査読有り
Austin James J., Wright Gareth S., Watanabe S, Grossman G, Antonyuk S V., Yamanaka K, Hasnan S. S
Proceedings of the National Academy of Sciences of the United States of America 111 巻 ( 11 ) 頁： 4309-4314 2014年3月
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Case of familial amyotrophic lateral sclerosis showing gadolinium-enhanced cranial nerves on magnetic resonance imaging associated with rapid progression of facial nerve palsy 査読有り
Mizuno M, Ueki Y, Sakurai K, Okita K, Endo F, Yamanaka K, Morita M, Matsukawa N
Neurology and Clinical Neuroscience 頁： -- 2014年2月
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Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis 査読有り
Nomura T, Watanabe S, Kaneko K, Yamanaka K, Nukina N, Furukawa Y
Journal of Biological Chemistry 289 巻 ( 2 ) 頁： 1192-1202 2014年1月
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Animal models for neurodegenerative disorders
Tsuiji H, Yamanaka K
Animal Biotechnology 頁： 39-56 2013年12月
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Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis 査読有り
Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N
FEBS Letters 587 巻 ( 16 ) 頁： 2500-2505 2013年8月
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E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. 査読有り
Mishra Amit K, Maheshiwari M, Chhangani D, Fujimori-T N, Endo F, Joshi Ajai P, Jana Nihar R, Yamanaka K
Neurobiology of Aging 34 巻 ( 4 ) 頁： 1310.e11-23 2013年4月
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Loss of TDP-43 causes age-dependent progressive motor neuron degeneration. 査読有り
Iguchi Y, Katsuno M, Niwa J, Takagi S, Ishigaki S, Ikenaka , Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki Shoichi, Tanaka F, Sobue G
Brain 136 巻 ( 5 ) 頁： 1371-1382 2013年2月
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Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. 査読有り
Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, Sobue G, Yamanaka K
EMBO Molecular Medicine 5 巻 ( 2 ) 頁： 221-234 2013年2月
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Deletion of TLR-Associted signaling adaptor TRIF significantly accelerates disease progression of ALS mice. 査読有り
Komine O, Fujimori-Tonou N, Yamashita H, Moriwaki Y, Misawa H, Yamanaka K
61 巻 頁： S75-S76 2013年
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The role of microglia-immune interaction in neurodegeneration of ALS mouse model.
Yamanaka K
Journal of Neurochemistry 125 巻 頁： 89 2013年
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Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked TDP-43 mutations. 査読有り
Watanabe S, Kaneko K, Yamanaka K
J Biol Chem 288 巻 頁： 3641-3654 2012年12月
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Disulfide scrambling describes the oligomer formation of SOD1 proteins in the familial form of ALS. 査読有り
Toichi K, Yamanaka K, Furukawa Y
J Biol Chem 288 巻 頁： 4970-1980 2012年12月
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E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. 査読有り
Mishra A, Maheshwari M, Chhangani D, Fujimori-Tonou N, Endo, F, Joshi AP, Jana NR, Yamanaka K
Neurobiol Aging 34 巻 ( 1310 ) 頁： e11-23 2012年10月
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A seeding reaction recapitulates intracellular formation of sarkosyl-insoluble TAR DNA binding protein-43 inclusions. 査読有り
Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N
J. Biol. Chem 286 巻 頁： 18664-18672 2011年
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Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's 査読有り
Takeuchi H, Mizoguchi H, Doi Y, Jin S, Noda M, Liang J, Li H, Zhou Y, Mori R, Yasuoka S, Li E, Parajuli B, Kawanokuchi J, Sonobe Y, Sato J, Yamanaka K, Sobue G, Mizuno T, Suzumura A
PLoS One 6 巻 ( 6 ) 頁： e21108 2011年
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Glial cells in Amyotrophic Lateral Sclerosis. 査読有り
Lasiene J, Yamanaka K
Neurol Res Int 頁： 718987 2011年