Faculty Profiles - TANAKA Akihito

Papers - TANAKA Akihito

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Accuracy and Safety of Newly Developed Optical-based FFR Device Compared to Conventional FFR Device

Suzuki Akihiro, Takashima Hiroaki, Saka Yuki, Waseda Katsuhisa, Ando Hirohiko, Nakano Yusuke, Sakurai Shinichiro, Fujimoto Masanobu, Ohashi Hirofumi, Tanaka Akihito, Ishii Hideki, Amano Tetsuya

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 73 ( 15 ) page： S68 - S68 2019.4

Saphenous Vein Graft Aneurysm 10 Years After Paclitaxel-Eluting Stent Implantation. Reviewed

Tanaka A, Jabbour RJ, Giannini F, Latib A, Colombo A

The Journal of invasive cardiology Vol. 29 ( 5 ) page： E63 2017.5

A Comparison Between First-Generation and Second-Generation Transcatheter Aortic Valve Implantation (TAVI) Devices: A Propensity-Matched Single-Center Experience. Reviewed International journal

Ruparelia N, Latib A, Kawamoto H, Buzzatti N, Giannini F, Figini F, Mangieri A, Regazzoli D, Stella S, Sticchi A, Tanaka A, Ancona M, Agricola E, Monaco F, Spagnolo P, Chieffo A, Montorfano M, Alfieri O, Colombo A

Journal of Invasive Cardiology Vol. 28 ( 5 ) page： 210 - 6 2016.5

Influence of the false lumen status on acute type A aortic dissection without urgent surgical repair

Tanaka A., Ishii H., Suzuki S., Ota T., Oshima H., Usui A., Murohara T.

EUROPEAN HEART JOURNAL Vol. 36 page： 1161 - 1161 2015.8

Association of estimated glomerular filtration rate and proteinuria with lipid-rich plaque in coronary artery disease Reviewed Open Access

Shimbo, Y., Suzuki, S., Ishii, H., Shibata, Y., Tatami, Y., Harata, S., Osugi, N., Ota, T., Tanaka, A., Shibata, K., Mizukoshi, T., Yasuda, Y., Maruyama, S., Murohara, T.

Circulation Journal Vol. 79 ( 10 ) page： 2263 - 2270 2015

Language：English Publishing type：Research paper (scientific journal) Publisher：The Japanese Circulation Society

Background:Estimated glomerular filtration rate (eGFR) and proteinuria are both important determinants of the risk of cardiovascular disease and mortality. The aim of the present study was to investigate the independent and combined effects of eGFR and proteinuria on tissue characterization of the coronary plaques of culprit lesions.Methods and Results:Conventional intravascular ultrasound and 3-D integrated backscatter intravascular ultrasound (IB-IVUS) were performed in 555 patients undergoing elective percutaneous coronary intervention. They were divided into 2 groups according to the absence or presence of proteinuria (dipstick result ≥1+). Patients with proteinuria had coronary plaque with significantly greater percentage lipid volume compared with those without (43.6±14.8% vs. 48.6±16.1%, P=0.005). Combined analysis was done using eGFR and absence or presence of proteinuria. Subjects with eGFR 45–59 ml/min/1.73 m2and proteinuria were significantly more likely to have higher percent lipid volume compared with those with eGFR >60 ml/min/1.73 m2without proteinuria. After multivariate adjustment for confounders, the presence of proteinuria proved to be an independent predictor for lipid-rich plaque (OR, 1.85; 95% CI: 1.12–3.06, P=0.016).Conclusions:The addition of proteinuria to eGFR level may be of value in the risk stratification of patients with coronary artery disease. (Circ J 2015; 79: 2263–2270)

DOI： 10.1253/circj.CJ-15-0460

Impact of airflow limitation on carotid atherosclerosis in coronary artery disease patients Reviewed Open Access

Hamrah, M.S., Suzuki, S., Ishii, H., Shibata, Y., Tatami, Y., Osugi, N., Ota, T., Kawamura, Y., Tanaka, A., Aso, H., Takeshita, K., Sakamoto, J., Hasegawa, Y., Murohara, T.

Respiration Vol. 89 ( 4 ) page： 322 - 328 2015

Assessment of in-stent restenosis using high-definition computed tomography with a new gemstone detector Reviewed International journal Open Access

Tsuda, T., Ishii, H., Ichimiya, S., Kanashiro, M., Watanabe, J., Takefuji, M., Aoyama, T., Suzuki, S., Tanaka, A., Matsubara, T., Murohara, T.

Circulation Journal Vol. 79 ( 7 ) page： 1542 - 1548 2015

Language：English Publishing type：Research paper (scientific journal) Publisher：The Japanese Circulation Society

Background:Until now, there have been few reports on the accuracy of in-stent restenosis (ISR) detection using high-definition computed tomography (HDCT). The purpose of this study was to assess ISR using HDCT with a new gemstone detector and to examine the diagnostic accuracy compared with invasive coronary angiography.Methods and Results:We evaluated 162 consecutive patients with 316 stents and the image quality (IQ) scores used to assess ISR, and analyzed whether stent strut thickness and diameter affected IQ score and assessability. In the 316 stents, 278 were diagnosed as assessable with HDCT (88.0%). IQ score for stent diameter ≥3 mm was significantly higher than that for stent diameter <3 mm, for stents with both thick struts ≥140 μm in thickness (mean IQ: 2.04±0.97 vs. 2.83±1.06, P<0.001) and thin struts <140 μm (mean IQ: 1.92±0.87 vs. 2.64±0.96, P=0.01). Assessability for stent diameter ≥3 mm was significantly higher than that for stent diameter <3 mm only for stents with thick struts (92.8% vs. 76.1%, P<0.001). Stent strut thickness, however, was not statistically significantly associated with either IQ score or assessability.Conclusions:In-stent lumens have high HDCT assessability, and HDCT is useful to evaluate thick-strut stents with diameter <3 mm.

DOI： 10.1253/circj.CJ-14-1344

Inverse association between diabetes and aortic dilatation in patients with advanced coronary artery disease Reviewed

Tanaka, A., Ishii, H., Oshima, H., Narita, Y., Kodama, A., Suzuki, S., Komori, K., Usui, A., Murohara, T.

Atherosclerosis Vol. 242 ( 1 ) page： 123 - 127 2015

Impact of low-grade albuminuria on left ventricular diastolic dysfunction Reviewed

Nagai, H., Suzuki, S., Ishii, H., Shibata, Y., Harata, S., Takayama, Y., Tatami, Y., Shimbo, Y., Osugi, N., Ota, T., Kawamura, Y., Tanaka, A., Takeshita, K., Murohara, T.

IJC Metabolic and Endocrine Vol. 6 page： 13 - 16 2015

Relation of airflow limitation and smoking status to carotid atherosclerosis in patients with coronary artery disease

Suzuki S., Ishii H., Shibata Y., Tatami Y., Osugi N., Ota T., Kawamura Y., Tanaka A., Murohara T.

EUROPEAN HEART JOURNAL Vol. 35 page： 902 - 902 2014.9

Impact of albuminuria on the incidence of peri-procedural myocardial injury in patients undergoing elective stent implantation

Suzuki S., Ishii H., Shibata Y., Tatami Y., Osugi N., Ota T., Kawamura Y., Tanaka A., Murohara T.

EUROPEAN HEART JOURNAL Vol. 35 page： 130 - 130 2014.9

Impact of albuminuria on the incidence of periprocedural myocardial injury in patients undergoing elective coronary stent implantation Reviewed Open Access

Osugi, N., Suzuki, S., Ishii, H., Yasuda, Y., Shibata, Y., Tatami, Y., Ota, T., Kawamura, Y., Okumura, S., Tanaka, A., Inoue, Y., Matsuo, S., Murohara, T.

American Journal of Cardiology Vol. 114 ( 1 ) page： 42 - 46 2014

Accelerated decline in renal function after acute myocardial infarction in patients with high low-density lipoprotein-cholesterol to high-density lipoprotein-cholesterol ratio Reviewed International journal

Okumura, S., Sakakibara, M., Hayashida, R., Jinno, Y., Tanaka, A., Okada, K., Hayashi, M., Ishii, H., Murohara, T.

Heart and Vessels Vol. 29 ( 1 ) page： 7 - 14 2014

Influence of the false lumen status on clinical outcomes in patients with acute type B aortic dissection Reviewed International journal Open Access

Tanaka, A., Sakakibara, M., Ishii, H., Hayashida, R., Jinno, Y., Okumura, S., Okada, K., Murohara, T.

Journal of Vascular Surgery Vol. 59 ( 2 ) page： 321 - 326 2014

Impact of chronic obstructive pulmonary disease on composition of left main coronary artery plaque with intermediate stenosis Reviewed

Kumagai, S., Ishii, H., Takashima, H., Waseda, K., Kurita, A., Ando, H., Gosho, M., Yoshikawa, D., Suzuki, S., Tanaka, A., Matsubara, T., Murohara, T., Amano, T.

International Journal of Cardiology Vol. 174 ( 3 ) page： 865 - 866 2014

Impact of serum bilirubin levels on carotid atherosclerosis in patients with coronary artery disease Reviewed

Tatami, Y., Suzuki, S., Ishii, H., Shibata, Y., Osugi, N., Ota, T., Kawamura, Y., Tanaka, A., Takeshita, K., Murohara, T.

IJC Metabolic and Endocrine Vol. 5 page： 24 - 27 2014

Elevated Fasting Glucose is an Important Risk Factor for Contrast-Induced Nephropathy in Non-Diabetic Patients with Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Okumura Satoshi, Sakakibara Masaki, Havashida Ryo, Tanaka Akihito, Jinno Yasushi, Okada Koji, Murohara Toyoaki

CIRCULATION Vol. 126 ( 21 ) 2012.11

Comparison of short and long term clinical outcomes according to status of the false lumen in patients with acute type B aortic dissection

Tanaka A., Sakakibara M., Hayashida R., Jinno Y., Okumura S., Okada K., Murohara T.

EUROPEAN HEART JOURNAL Vol. 33 page： 243 - 243 2012.8

Comparison of early outcomes after primary stenting in Japanese patients with acute myocardial infarction between clopidogrel and ticlopidine in concomitant use with proton-pump inhibitor Reviewed Open Access

Tanaka, A., Sakakibara, M., Okumura, S., Okada, K., Ishii, H., Murohara, T.

Journal of Cardiology Vol. 60 ( 1 ) page： 7 - 11 2012

Does N-acetylcysteine reduce the incidence of contrast-induced nephropathy and clinical events in patients undergoing primary angioplasty for acute myocardial infarction? Reviewed Open Access

Tanaka, A., Suzuki, Y., Suzuki, N., Hirai, T., Yasuda, N., Miki, K., Fujita, M., Tanaka, T.

Internal Medicine Vol. 50 ( 7 ) page： 673 - 677 2011

Authorship：Lead author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：The Japanese Society of Internal Medicine

Objectives We examined oral N-acetylcysteine effects on contrast-induced nephropathy (CIN) and clinical events in patients undergoing primary angioplasty for acute myocardial infarction. Background Recent studies have reported that N-acetylcysteine reduces CIN and improves the clinical outcome in patients undergoing primary angioplasty. However, additional investigations are warranted to further support these findings. Methods We randomly assigned 76 patients undergoing primary angioplasty into two groups: 38 patients were assigned to N-acetylcysteine (NAC, 705 mg orally administration before and 12, 24, 36 hours after primary angioplasty), and 38 patients to placebo. CIN was defined as an increase in the serum creatinine concentration of 25 percent or more from baseline value within the 72-hour period after primary angioplasty. Results CIN occurred in 7 patients (9.2%). In the NAC group, the incidence of CIN tended to be lower than in the placebo group (NAC; 2/38; 5.3% vs. Placebo; 5/38; 13.2%, p=0.21). The composite endpoints such as death, acute renal failure requiring temporary renal replacement therapy, or need for mechanical ventilation did not occur in either group. Conclusion While N-acetylcysteine might have the possibility to reduce the incidence of contrast-induced nephropathy in patients undergoing primary angioplasty for acute myocardial infarction, the in-hospital mortality and morbidity were not significantly different between the two groups.

DOI： 10.2169/internalmedicine.50.4226

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