Papers - YAMANAKA Koji
-
Neuroinflammation in motor neuron disease.
Komine O, Yamanaka K
Nagoya Journal of Medical Science Vol. 77 ( 4 ) page： 537-549 2015.11
-
Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Reviewed International coauthorship
Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A
Neurobiology of Disease Vol. 86 page： 16-28 2015.11
-
Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity. Reviewed
Watanabe S, Hayakawa T, Wakasugi K, Yamanaka K
Cell Death and Disease Vol. 5 page： e1497 2014.10
-
SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system. Reviewed
Watanabe S, Ageta-Ishihara N, Nagatsu S, Takao K, Komine O, Endo F, Miyakawa T, Misawa H, Takahashi R, Kinoshita M, Yamanaka K
Molecular Brain Vol. 7 ( 62 ) 2014.8
-
Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life. Reviewed
Austin James J., Wright Gareth S., Watanabe S, Grossman G, Antonyuk S V., Yamanaka K, Hasnan S. S
Proceedings of the National Academy of Sciences of the United States of America Vol. 111 ( 11 ) page： 4309-4314 2014.3
-
Case of familial amyotrophic lateral sclerosis showing gadolinium-enhanced cranial nerves on magnetic resonance imaging associated with rapid progression of facial nerve palsy Reviewed
Mizuno M, Ueki Y, Sakurai K, Okita K, Endo F, Yamanaka K, Morita M, Matsukawa N
Neurology and Clinical Neuroscience page： -- 2014.2
-
Intranuclear aggregation of mutant FUS/TLS as a molecular pathomechanism of amyotrophic lateral sclerosis Reviewed
Nomura T, Watanabe S, Kaneko K, Yamanaka K, Nukina N, Furukawa Y
Journal of Biological Chemistry Vol. 289 ( 2 ) page： 1192-1202 2014.1
-
Animal models for neurodegenerative disorders
Tsuiji H, Yamanaka K
Animal Biotechnology page： 39-56 2013.12
-
Intracellular seeded aggregation of mutant Cu,Zn-superoxide dismutase associated with amyotrophic lateral sclerosis Reviewed
Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N
FEBS Letters Vol. 587 ( 16 ) page： 2500-2505 2013.8
-
E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. Reviewed
Mishra Amit K, Maheshiwari M, Chhangani D, Fujimori-T N, Endo F, Joshi Ajai P, Jana Nihar R, Yamanaka K
Neurobiology of Aging Vol. 34 ( 4 ) page： 1310.e11-23 2013.4
-
Loss of TDP-43 causes age-dependent progressive motor neuron degeneration. Reviewed
Iguchi Y, Katsuno M, Niwa J, Takagi S, Ishigaki S, Ikenaka , Kawai K, Watanabe H, Yamanaka K, Takahashi R, Misawa H, Sasaki Shoichi, Tanaka F, Sobue G
Brain Vol. 136 ( 5 ) page： 1371-1382 2013.2
-
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. Reviewed
Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, Tanaka F, Hashizume Y, Akatsu H, Murayama S, Sobue G, Yamanaka K
EMBO Molecular Medicine Vol. 5 ( 2 ) page： 221-234 2013.2
-
Deletion of TLR-Associted signaling adaptor TRIF significantly accelerates disease progression of ALS mice. Reviewed
Komine O, Fujimori-Tonou N, Yamashita H, Moriwaki Y, Misawa H, Yamanaka K
Vol. 61 page： S75-S76 2013
-
The role of microglia-immune interaction in neurodegeneration of ALS mouse model.
Yamanaka K
Journal of Neurochemistry Vol. 125 page： 89 2013
-
Accelerated disease onset with stabilized familial amyotrophic lateral sclerosis (ALS)-linked TDP-43 mutations. Reviewed
Watanabe S, Kaneko K, Yamanaka K
J Biol Chem Vol. 288 page： 3641-3654 2012.12
-
Disulfide scrambling describes the oligomer formation of SOD1 proteins in the familial form of ALS. Reviewed
Toichi K, Yamanaka K, Furukawa Y
J Biol Chem Vol. 288 page： 4970-1980 2012.12
-
E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity. Reviewed
Mishra A, Maheshwari M, Chhangani D, Fujimori-Tonou N, Endo, F, Joshi AP, Jana NR, Yamanaka K
Neurobiol Aging Vol. 34 ( 1310 ) page： e11-23 2012.10
-
A seeding reaction recapitulates intracellular formation of sarkosyl-insoluble TAR DNA binding protein-43 inclusions. Reviewed
Furukawa Y, Kaneko K, Watanabe S, Yamanaka K, Nukina N
J. Biol. Chem Vol. 286 page： 18664-18672 2011
-
Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Reviewed
Takeuchi H, Mizoguchi H, Doi Y, Jin S, Noda M, Liang J, Li H, Zhou Y, Mori R, Yasuoka S, Li E, Parajuli B, Kawanokuchi J, Sonobe Y, Sato J, Yamanaka K, Sobue G, Mizuno T, Suzumura A
PLoS One Vol. 6 ( 6 ) page： e21108 2011
-
Glial cells in Amyotrophic Lateral Sclerosis. Reviewed
Lasiene J, Yamanaka K
Neurol Res Int page： 718987 2011