Papers - YAMANAKA Koji
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Dissociation of blood-brain barrier disruption and disease manifestation in an aquaporin-4-deficient mouse model of amyotrophic lateral sclerosis Reviewed
Watanabe-Matsumoto S, Moriwaki Y, Okuda T, Ohara S, Yamanaka K, Abe Y, Yasui M, Misawa H
Neuroscience Research Vol. 133 page： 48-57 2018.8
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A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis
Tokuda Eiichi, Nomura Takao, Ohara Shinji, Watanabe Seiji, Yamanaka Koji, Morisaki Yuta, Misawa Hidemi, Furukawa Yoshiaki
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE Vol. 1864 ( 6 ) page： 2119 - 2130 2018.6
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Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice Reviewed
Watanabe S, Komine O, Endo F, Wakasugi K, Yamanaka K
Journal of Neurochemistry Vol. 145 ( 1 ) page： 80-89 2018.4
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Innate immune adaptor TRIF deficiency accelerates disease progression of ALS mice with accumulation of aberrantly activated astrocytes. Reviewed
Komine O, Yamashita H, Fujimori-Tonou N, Koike M, Jin S, Moriwaki Y, Endo F, Watanabe S, Uematsu S, Akira S, Uchiyama Y, Takahashi R, Misawa H, Yamanaka K
Cell Death and Differentiation Vol. 25 ( 12 ) page： 2130-2146 2018.3
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The Multi-dimensional roles of astrocytes in ALS. Invited Reviewed
Yamanaka K, Komine O
Neuroscience Research Vol. 126 page： 31 - 38 2018.1
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TDP-43 accelerates age-dependent degeneration of interneurons Reviewed
Tsuiji H, Inoue I, Takeuchi M, Furuya A, Yamakage Y, Watanabe S, Koike M, Hattori M, Yamanaka K
Scientific Reports Vol. 7 page： 14972 2017.11
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Astrocyte-derived extracellular vesicles contribute to the propagation of pathogenic protein in ALS
Endo F., Kurita T., Yamanaka K.
JOURNAL OF THE NEUROLOGICAL SCIENCES Vol. 381 page： 203 - 204 2017.10
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Watanabe S., Ilieva H., Tamada H., Nomura H., Komine O., Endo F., Jin S., Mancias P., Kiyama H., Yamanaka K.
JOURNAL OF THE NEUROLOGICAL SCIENCES Vol. 381 page： 104 - 104 2017.10
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Mice heterozygously lacking C-terminal domain of TDP-43 show age-dependent motor dysfunction
Nishino K, Watanabe S, Komine O, Yamanaka K.
Journal of the Neurological Sciences Vol. 381 page： 570 2017.10
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Age-dependent motor dysfunction due to neuron-specific disruption of stress-activated protein kinase MKK7. Reviewed
Yamasaki T, Deki-Arima N, Kaneko A, Miyamura N, Iwatsuki M, Matsuoka M, Fujimori-Tonou N, Okamoto-Uchida Y, Hirayama J, Marth JD, Yamanashi Y, Kawasaki H, Yamanaka K, Penninger JM, Shibata S, Nishina H
Scientific Reports Vol. 7 page： 7348 2017.8
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A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis. Reviewed
Anzai I, Tokuda E, Mukaiyama A, Akiyama S, Endo F, Yamanaka K, Misawa H, Furukawa Y.
Protein Sci Vol. 26 ( 3 ) page： 484-496 2017.3
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A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis
Anzai Itsuki, Tokuda Eiichi, Mukaiyama Atsushi, Akiyama Shuji, Endo Fumito, Yamanaka Koji, Misawa Hidemi, Furukawa Yoshiaki
PROTEIN SCIENCE Vol. 26 ( 3 ) page： 484 - 496 2017.3
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Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis. Reviewed
Tokuda E, Anzai I, Nomura T, Toichi K, Watanabe M, Ohara S, Watanabe S, Yamanaka K, Morisaki Y, Misawa H, Furukawa Y.
Molecular Neurodegeneration Vol. 12 page： 2 2017.1
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Immunochemical characterization on pathological oligomers of mutant Cu/Znsuperoxide dismutase in amyotrophic lateral sclerosis
Tokuda Eiichi, Anzai Itsuki, Nomura Takao, Toichi Keisuke, Watanabe Masahiko, Ohara Shinji, Watanabe Seiji, Yamanaka Koji, Morisaki Yuta, Misawa Hidemi, Furukawa Yoshiaki
MOLECULAR NEURODEGENERATION Vol. 12 ( 1 ) page： 2 2017.1
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Proteasomal dysfunction induced by diclofenac engenders apoptosis through mitochondrial pathway
Amanullah A, Upadhyay A, Chhangani D, Joshi V, Mishra R, Yamanaka K, Mishra A
J. Cell. Biochem. 2016.8
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Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9 Reviewed
Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, Okuda T, Ohara S, Murayama S, Takao M, Uchida S, Yamanaka K, Misawa H.
Scientific Reports Vol. 6 page： 27354 2016.6
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Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons. Reviewed
Lasiene J, Komine O, Fujimori-Tonou. N, Powers B, Endo F, Watanabe S, Shjie J, Ravits J, Horner P, Misawa H, Yamanaka K
Acta Neuropathologica Communications Vol. 18 ( 4 ) 2016.2
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Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model. Reviewed International coauthorship
Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A
Neurobiology of Disease Vol. 86 page： 16-28 2015.11
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Neuroinflammation in motor neuron disease.
Komine O, Yamanaka K
Nagoya Journal of Medical Science Vol. 77 ( 4 ) page： 537-549 2015.11
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Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity. Reviewed
Watanabe S, Hayakawa T, Wakasugi K, Yamanaka K
Cell Death and Disease Vol. 5 page： e1497 2014.10