研究者詳細 - 森　健策

論文 - 森　健策

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[Pharmacological action and clinical effect of tedizolid phosphate (SIVEXTRO® Tablets 200 mg, for iv infusion 200 mg), a novel oxazolidinone-class antibacterial drug]. 招待有り査読有り

Mori M, Takase A

Nihon yakurigaku zasshi. Folia pharmacologica Japonica 155 巻 ( 5 ) 頁： 332 - 339 2020年

2. 多元計算解剖モデルと人工知能に基づく診断治療支援招待有り Open Access

森健策

映像情報メディア学会誌 74 巻 ( 6 ) 頁： 909 - 915 2020年

A view of three dimensional unit structures of alveoli in peripheral lung 招待有り査読有り

Natori, H; Takabatake, H; Mori, M; Oda, M; Mori, K; Koba, H; Takahashi, H

EUROPEAN RESPIRATORY JOURNAL 54 巻 2019年9月

Development of a new laparoscopic detection system for gastric cancer using near-infrared light-emitting clips with glass phosphor 招待有り査読有り Open Access

Inada S., Nakanishi H., Oda M., Mori K., Ito A., Hasegawa J., Misawa K., Fuchi S.

Micromachines 10 巻 ( 2 ) 2019年1月

担当区分：責任著者記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Micromachines

Laparoscopic surgery is now a standard treatment for gastric cancer. Currently, the location of the gastric cancer is identified during laparoscopic surgery via the preoperative endoscopic injection of charcoal ink around the primary tumor; however, the wide spread of injected charcoal ink can make it difficult to accurately visualize the specific site of the tumor. To precisely identify the locations of gastric tumors, we developed a fluorescent detection system comprising clips with glass phosphor (Yb 3+ , Nd 3+ doped to Bi 2 O 3 -B 2 O 3 -based glasses, size: 2 mm × 1 mm × 3 mm) fixed in the stomach and a laparoscopic fluorescent detection system for clip-derived near-infrared (NIR) light (976 nm). We conducted two ex vivo experiments to evaluate the performance of this fluorescent detection system in an extirpated pig stomach and a freshly resected human stomach and were able to successfully detect NIR fluorescence emitted from the clip in the stomach through the stomach wall by the irradiation of excitation light (λ: 808 nm). These results suggest that the proposed combined NIR light-emitting clip and laparoscopic fluorescent detection system could be very useful in clinical practice for accurately identifying the location of a primary gastric tumor during laparoscopic surgery.

DOI： 10.3390/mi10020081

Open Access

Scopus

Automated Hand Eye Calibration in Laparoscope Holding Robot for Robot Assisted Surgery 査読有り

Jiang, S; Hayashi, Y; Wang, C; Oda, M; Kitasaka, T; Misawa, K; Mori, K

INTERNATIONAL WORKSHOP ON ADVANCED IMAGE TECHNOLOGY (IWAIT) 2019 11049 巻 2019年

Colonoscope tracking method based on shape estimation network 招待有り査読有り Open Access

Oda Masahiro, Roth Holger R., Kitasaka Takayuki, Furukawa Kazuhiro, Miyahara Ryoji, Hirooka Yoshiki, Navab Nassir, Mori Kensaku

MEDICAL IMAGING 2019: IMAGE-GUIDED PROCEDURES, ROBOTIC INTERVENTIONS, AND MODELING 10951 巻 2019年

担当区分：責任著者記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Progress in Biomedical Optics and Imaging - Proceedings of SPIE

This paper presents a colonoscope tracking method utilizing a colon shape estimation method. CT colonography is used as a less-invasive colon diagnosis method. If colonic polyps or early-stage cancers are found, they are removed in a colonoscopic examination. In the colonoscopic examination, understanding where the colonoscope running in the colon is difficult. A colonoscope navigation system is necessary to reduce overlooking of polyps. We propose a colonoscope tracking method for navigation systems. Previous colonoscope tracking methods caused large tracking errors because they do not consider deformations of the colon during colonoscope insertions. We utilize the shape estimation network (SEN), which estimates deformed colon shape during colonoscope insertions. The SEN is a neural network containing long short-term memory (LSTM) layer. To perform colon shape estimation suitable to the real clinical situation, we trained the SEN using data obtained during colonoscope operations of physicians. The proposed tracking method performs mapping of the colonoscope tip position to a position in the colon using estimation results of the SEN. We evaluated the proposed method in a phantom study. We confirmed that tracking errors of the proposed method was enough small to perform navigation in the ascending, transverse, and descending colons.

DOI： 10.1117/12.2512729

Web of Science

Scopus

Atmospheric gas dynamics in the Perseus cluster observed with Hitomi 招待有り査読有り

Aharonia F., Aharonian F., Akamatsu H., Akimoto F., Allen S.W., Angelini L., Audard M., Awaki H., Axelsson M., Bamba A., Bautz M.W., Blandford R., Brenneman L.W., Brown G.V., Bulbul E., Cackett E.M., Canning R.E.A., Chernyakova M., Chiao M.P., Coppi P.S., Costantini E., De Plaa J., De Vries C.P., Den Herder J.W., Done C., Dotani T., Ebisawa K., Eckart M.E., Enoto T., Ezoe Y., Fabian A.C., Ferrigno C., Foster A.R., Fujimoto R., Fukazawa Y., Furuzawa A., Galeazzi M., Gallo L.C., Gandhi P., Giustini M., Goldwurm A., Gu L., Guainazzi M., Haba Y., Hagino K., Hamaguchi K., Harrus I.M., Hatsukade I., Hayashi K., Hayashi T., Hayashi T., Hayashida K., Hiraga J.S., Hornschemeier A., Hoshino A., Hughes J.P., Ichinohe Y., Iizuka R., Inoue H., Inoue S., Inoue Y., Ishida M., Ishikawa K., Ishisaki Y., Iwai M., Kaastra J., Kallman T., Kamae T., Kataoka J., Katsuda S., Kawai N., Kelley R.L., Kilbourne C.A., Kitaguchi T., Kitamoto S., Kitayama T., Kohmura T., Kokubun M., Koyama K., Koyama S., Kretschmar P., Krimm H.A., Kubota A., Kunieda H., Laurent P., Lee S.H., Leutenegger M.A., Limousin O., Loewenstein M., Long K.S., Lumb D., Madejski G., Maeda Y., Maier D., Makishima K., Markevitch M., Matsumoto H., Matsushita K., Mccammon D., Mcnamara B.R.

Publications of the Astronomical Society of Japan 70 巻 ( 2 ) 2018年3月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Publications of the Astronomical Society of Japan

Extending the earlier measurements reported in Hitomi collaboration (2016, Nature, 535, 117), we examine the atmospheric gas motions within the central 100kpc of the Perseus cluster using observations obtained with the Hitomi satellite. After correcting for the point spread function of the telescope and using optically thin emission lines, we find that the line-of-sight velocity dispersion of the hot gas is remarkably low and mostly uniform. The velocity dispersion reaches a maxima of approximately 200 km s-1 toward the central active galactic nucleus (AGN) and toward the AGN inflated northwestern "ghost" bubble. Elsewhere within the observed region, the velocity dispersion appears constant around 100 km s-1. We also detect a velocity gradient with a 100 km s-1 amplitude across the cluster core, consistent with large-scale sloshing of the core gas. If the observed gas motions are isotropic, the kinetic pressure support is less than 10% of the thermal pressure support in the cluster core. The well-resolved, optically thin emission lines have Gaussian shapes, indicating that the turbulent driving scale is likely below 100 kpc, which is consistent with the size of the AGN jet inflated bubbles. We also report the first measurement of the ion temperature in the intracluster medium, which we find to be consistent with the electron temperature. In addition, we present a new measurement of the redshift of the brightest cluster galaxy NGC 1275.

Scopus

Automatic segmentation of eyeball structures from micro-CT images based on sparse annotation 招待有り査読有り

Sugino Takaaki, Roth Holger R., Oda Masahiro, Omata Seiji, Sakuma Shinya, Arai Fumihito, Mori Kensaku

MEDICAL IMAGING 2018: BIOMEDICAL APPLICATIONS IN MOLECULAR, STRUCTURAL, AND FUNCTIONAL IMAGING 10578 巻頁： 105780V-1-105780V-6 2018年

Cascade classification of endocytoscopic images of colorectal lesions for automated pathological diagnosis 招待有り査読有り

Itoh Hayato, Mori Yuichi, Misawa Masashi, Oda Masahiro, Kudo Shin-ei, Mori Kensaku

MEDICAL IMAGING 2018: COMPUTER-AIDED DIAGNOSIS 10575 巻頁： 1057516-1-1057516-6 2018年

3Dプリンタの最新動向招待有り

森健策

インナービジョン 33 巻頁： 35 - 36 2018年

BESNet: Boundary-Enhanced Segmentation of Cells in Histopathological Images 招待有り査読有り

Oda Hirohisa, Roth Holger R., Chiba Kosuke, Sokolic Jure, Kitasaka Takayuki, Oda Masahiro, Hinoki Akinari, Uchida Hiroo, Schnabel Julia A., Mori Kensaku

MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2018, PT II 11071 巻頁： 228 - 236 2018年

Colon Shape Estimation Method for Colonoscope Tracking Using Recurrent Neural Networks 招待有り査読有り Open Access

Oda Masahiro, Roth Holger R., Kitasaka Takayuki, Furukawa Kasuhiro, Miyahara Ryoji, Hirooka Yoshiki, Goto Hidemi, Navab Nassir, Mori Kensaku

MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2018, PT IV 11073 巻頁： 176 - 184 2018年

Deep Learning and Its Application to Medical Image Segmentation 招待有り査読有り

ROTH Holger R., SHEN Chen, ODA Hirohisa, ODA Masahiro, HAYASHI Yuichiro, MISAWA Kazunari, MORI Kensaku

Medical Imaging Technology 36 巻 ( 2 ) 頁： 63 - 71 2018年

担当区分：責任著者記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：The Japanese Society of Medical Imaging Technology

One of the most common tasks in medical imaging is semantic segmentation. Achieving this segmentation automatically has been an active area of research, but the task has been proven very challenging due to the large variation of anatomy across different patients. However, recent advances in deep learning have made it possible to significantly improve the performance of image recognition and semantic segmentation methods in the field of computer vision. Due to the data driven approaches of hierarchical feature learning in deep learning frameworks, these advances can be translated to medical images without much difficulty. Several variations of deep convolutional neural networks have been successfully applied to medical images. Especially fully convolutional architectures have been proven efficient for segmentation of 3D medical images. In this article, we describe how to build a 3D fully convolutional network (FCN) that can process 3D images in order to produce automatic semantic segmentations. The model is trained and evaluated on a clinical computed tomography (CT) dataset and shows stateof-the-art performance in multi-organ segmentation.

DOI： 10.11409/mit.36.63

CiNii Research

Develop and Validate a Finite Element Method Model for Deformation Matching of Laparoscopic Gastrectomy Navigation 招待有り査読有り

Chen Tao, Wei Guodong, Shi Weili, Hayashi Yuichiro, Oda Masahiro, Jiang Zhengang, Li Guoxin, Mori Kensaku

MEDICAL IMAGING 2018: IMAGE-GUIDED PROCEDURES, ROBOTIC INTERVENTIONS, AND MODELING 10576 巻 2018年

Airway Segmentation from 3D Chest CT Volumes Based on Volume of Interest Using Gradient Vector Flow 招待有り査読有り

MENG Qier, KITASAKA Takayuki, ODA Masahiro, UENO Junji, MORI Kensaku

Medical Imaging Technology 36 巻 ( 3 ) 頁： 133 - 146 2018年

担当区分：責任著者記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：The Japanese Society of Medical Imaging Technology

In this paper, we propose a new airway segmentation algorithm from 3D chest CT volumes based on the volume of interest (VOI). The algorithm segments each bronchial branch by recognizing the airway regions from the trachea using the VOIs to segment each branch. A VOI is placed to envelop the branch currently being processed. Then a cavity enhancement filter is performed only inside the current VOI so that each branch is extracted. At the same time, we perform a leakage detection scheme to avoid any leakage regions inside the VOI. Next the gradient vector flow magnitude map and a tubular-likeness function are computed in each VOI. This assists the predictions of both the position and direction of the next child VOIs to detect the next child branches to continue the tracking algorithm. Finally, we unify all of the extracted airway regions to form a complete airway tree. We used a dataset that includes 50 standard-dose human chest CT volumes to evaluate our proposed algorithm. The average extraction rate was approximately 78.1% with a significantly decreased false positive rate compared to the previous method.

DOI： 10.11409/mit.36.133

CiNii Research

3Dプリンターの基礎と医療応用 招待有り査読有り

森健策

心臓 49 巻 ( 11 ) 頁： 1104 - 1113 2017年11月

Automated mediastinal lymph node detection from CT volumes based on intensity targeted radial structure tensor analysis 招待有り

Hirohisa Oda, Kanwal K. Bhatia, Masahiro Oda, Takayuki Kitasaka, Shingo Iwano, Hirotoshi Homma, Hirotsugu Takabatake, Masaki Mori, Hiroshi Natori, Julia A. Schnabel, Kensaku Mori

Journal of Medical Imaging 4 巻 ( 04 ) 頁： 1 2017年11月

Automatic segmentation of head anatomical structures from sparsely-Annotated images 招待有り査読有り

Sugino T., Roth H.R., Eshghi M., Oda M., Chung M.S., Mori K.

2017 IEEE International Conference on Cyborg and Bionic Systems, CBS 2017 2018-January 巻頁： 145 - 149 2017年7月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：2017 IEEE International Conference on Cyborg and Bionic Systems, CBS 2017

Bionic humanoid systems, which are elaborate human models with sensors, have been developed as a tool for quantitative evaluation of doctors' psychomotor skills and medical device performances. For creation of the elaborate human models, this study presents automated segmentation of head sectioned images using sparsely-Annotated data based on deep convolutional neural network. We applied the following fully convolutional networks (FCNs) to the sparse-Annotation-based segmentation: a standard FCN and a dilated convolution based FCN. To validate the availability of FCNs for segmentation of head structures from sparse annotation, we performed 8- and 243-label segmentation experiments using different two sets of head sectioned images in the Visible Korean Human project. In the segmentation experiments, only 10% of all images in each data set were used for training data. Both of the FCNs could achieve the mean segmentation accuracy of more than 85% in the 8-label segmentation. In the 243-label segmentation, though the mean segmentation accuracy was about 50%, the results suggested that the FCNs, especially the dilated convolution based FCNs, had potential to achieve accurate segmentation of anatomical structures, except for small-sized and complex-shaped tissues, even from sparse annotation.

DOI： 10.1109/CBS.2017.8266085

Scopus

Can Artificial Intelligence Correctly Diagnose Sessile Serrated Adenomas/Polyps? 招待有り査読有り

Mori Yuichi, Kudo Shinei, Ogawa Yushi, Misawa Masashi, Takeda Kenichi, Kudo Toyoki, Wakamura Kunihiko, Hayashi Takemasa, Ichimasa Katsuro, Maeda Yasuharu, Toyoshima Naoya, Nakamura Hiroki, Katagiri Atsushi, Baba Toshiyuki, Ishida Fumio, Oda Masahiro, Mori Kensaku, Inoue Haruhiro

GASTROINTESTINAL ENDOSCOPY 85 巻 ( 5 ) 頁： AB510 - AB510 2017年5月

Computer-Aided Diagnosis Based on Endocytoscopy With Narrow-Band Imaging Allows Accurate Diagnosis of Diminutive Colorectal Lesions 招待有り査読有り

Misawa Masashi, Kudo Shinei, Mori Yuichi, Takeda Kenichi, Kataoka Shinichi, Nakamura Hiroki, Maeda Yasuharu, Ogawa Yushi, Yamauchi Akihiro, Igarashi Kenta, Hayashi Takemasa, Kudo Toyoki, Wakamura Kunihiko, Katagiri Atsushi, Baba Toshiyuki, Ishida Fumio, Oda Masahiro, Mori Kensaku

GASTROINTESTINAL ENDOSCOPY 85 巻 ( 5 ) 頁： AB57 - AB57 2017年5月

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