Faculty Profiles - MORI, Kensaku

Papers - MORI, Kensaku

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Intelligent Image Synthesis to Attack a segmentation CNN Using Adversarial Learning

Liang Chen, Paul Bentley, Kensaku Mori, Kazunari Misawa, Michitaka Fujiwara, Daniel Rueckert,

LNCS11827 page： 90-99 2019.10

Spaciousness Filters for Non-contrast CT Volume Segmentation of the Intestine Region for Emergency Ileus Diagnosis

Hirohisa Oda, Kohei Nishio, Takayuki Kitasaka, Benjamin Villard, Hizuru Amano, Kosuke Chiba, Akinari Hinoki, Hiroo Uchida, Kojiro Suzuki, Hayato Itoh, Masahiro Oda, Kensaku Mori

LNCS 11840 page： 104-114 2019.10

Artificial Intelligence-assisted System Improves Endoscopic Identification of Colorectal Neoplasms. Reviewed International journal

Shin-Ei Kudo, Masashi Misawa, Yuichi Mori, Kinichi Hotta, Kazuo Ohtsuka, Hiroaki Ikematsu, Yutaka Saito, Kenichi Takeda, Hiroki Nakamura, Katsuro Ichimasa, Tomoyuki Ishigaki, Naoya Toyoshima, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Toshiyuki Baba, Ishida Fumio, Haruhiro Inoue, Hayato Itoh, Masahiro Oda, Kensaku Mori

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Vol. 18 ( 8 ) page： 1874 - 1881 2019.9

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND & AIMS: Precise optical diagnosis of colorectal polyps could improve the cost-effectiveness of colonoscopy and reduce polypectomy-related complications. However, it is difficult for community-based non-experts to obtain sufficient diagnostic performance. Artificial intelligence-based systems have been developed to analyze endoscopic images; they identify neoplasms with high accuracy and low interobserver variation. We performed a multi-center study to determine the diagnostic accuracy of EndoBRAIN, an artificial intelligence-based system that analyzes cell nuclei, crypt structure, and microvessels in endoscopic images, in identification of colon neoplasms. METHODS: The EndoBRAIN system was initially trained using 69,142 endocytoscopic images, taken at 520-fold magnification, from patients with colorectal polyps who underwent endoscopy at 5 academic centers in Japan from October 2017 through March 2018. We performed a retrospective comparative analysis of the diagnostic performance of EndoBRAIN vs that of 30 endoscopists (20 trainees and 10 experts); the endoscopists assessed images from 100 cases produced via white-light microscopy, endocytoscopy with methylene blue staining, and endocytoscopy with narrow-band imaging. EndoBRAIN was used to assess endocytoscopic, but not white-light, images. The primary outcome was the accuracy of EndoBrain in distinguishing neoplasms from non-neoplasms, compared with that of endoscopists, using findings from pathology analysis as the reference standard. RESULTS: In analysis of stained endocytoscopic images, EndoBRAIN identified colon lesions with 96.9% sensitivity (95% CI, 95.8%-97.8%), 100% specificity (95% CI, 99.6%-100%), 98% accuracy (95% CI, 97.3%-98.6%), a 100% positive-predictive value (95% CI, 99.8%-100%), and a 94.6% negative-predictive (95% CI, 92.7%-96.1%); these values were all significantly greater than those of the endoscopy trainees and experts. In analysis of narrow-band images, EndoBRAIN distinguished neoplastic from non-neoplastic lesions with 96.9% sensitivity (95% CI, 95.8-97.8), 94.3% specificity (95% CI, 92.3-95.9), 96.0% accuracy (95% CI, 95.1-96.8), a 96.9% positive-predictive value, (95% CI, 95.8-97.8), and a 94.3% negative-predictive value (95% CI, 92.3-95.9); these values were all significantly higher than those of the endoscopy trainees, sensitivity and negative-predictive value were significantly higher but the other values are comparable to those of the experts. CONCLUSIONS: EndoBRAIN accurately differentiated neoplastic from non-neoplastic lesions in stained endocytoscopic images and endocytoscopic narrow-band images, when pathology findings were used as the standard. This technology has been authorized for clinical use by the Japanese regulatory agency and should be used in endoscopic evaluation of small polyps more widespread clinical settings. UMIN clinical trial no: UMIN000028843.

DOI： 10.1016/j.cgh.2019.09.009

Scopus

PubMed

人工知能による画像診断支援-どこまでできたか.そして,その先は？

森健策

第46回日本小児内視鏡研究会プログラム・抄録集 page： 11 2019.7

Artificial intelligence and upper gastrointestinal endoscopy: Current status and future perspective. International journal

Yuichi Mori, Shin-Ei Kudo, Hussein E N Mohmed, Masashi Misawa, Noriyuki Ogata, Hayato Itoh, Masahiro Oda, Kensaku Mori

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society Vol. 31 ( 4 ) page： 378 - 388 2019.7

Language：Japanese Publishing type：Research paper (scientific journal)

With recent breakthroughs in artificial intelligence, computer-aided diagnosis (CAD) for upper gastrointestinal endoscopy is gaining increasing attention. Main research focuses in this field include automated identification of dysplasia in Barrett's esophagus and detection of early gastric cancers. By helping endoscopists avoid missing and mischaracterizing neoplastic change in both the esophagus and the stomach, these technologies potentially contribute to solving current limitations of gastroscopy. Currently, optical diagnosis of early-stage dysplasia related to Barrett's esophagus can be precisely achieved only by endoscopists proficient in advanced endoscopic imaging, and the false-negative rate for detecting gastric cancer is approximately 10%. Ideally, these novel technologies should work during real-time gastroscopy to provide on-site decision support for endoscopists regardless of their skill; however, previous studies of these topics remain ex vivo and experimental in design. Therefore, the feasibility, effectiveness, and safety of CAD for upper gastrointestinal endoscopy in clinical practice remain unknown, although a considerable number of pilot studies have been conducted by both engineers and medical doctors with excellent results. This review summarizes current publications relating to CAD for upper gastrointestinal endoscopy from the perspective of endoscopists and aims to indicate what is required for future research and implementation in clinical practice.

DOI： 10.1111/den.13317

Artificial intelligence and upper gastrointestinal endoscopy: current status and future perspective Reviewed

Yuichi Mori, Shinei Kudo, Hussein Ebaid Naeem Mohmed, Masashi Misawa, Noriyuki Ogata, Hayato Itoh, Masahiro Oda, Kensaku Mori

Digestive endoscopy Vol. 34 ( 4 ) page： 378-388 2019.7

大腸内視鏡（コロノスコピー）画像診断支援ソフトウェアの開発

森健策

インナービジョン 2019年7月号 Vol. 34 ( 7 ) page： 45 2019.7

内視鏡検査手術における超音波画像の利用-マルチモダリティ画像統合-

森健策

計測と制御 Vol. 58 ( 7 ) page： 541-544 2019.7

単眼腹腔鏡映像からの奥行き推定を利用した術具セグメンテーション

鈴木拓矢, 道満恵介, 目加田慶人, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集 page： OP1-11 2019.7

多元計算解剖学のその先にあるもの

森　健策

第38回日本医用画像工学会大会予稿集 page： SY2-5 2019.7

3D fully convolutional network を用いた腎腫瘍の定量評価における初期検討

王成龍, 小田昌宏, 林雄一郎, 佐々直人, 山本徳則, 森健策

第38回日本医用画像工学会大会予稿集 page： OP5-23 2019.7

深層学習を用いた非造影 CT 画像からの複数臓器領域の抽出に関する検討

林雄一郎, 申忱, Roth Holger, 小田昌宏, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集 page： OP5-14 2019.7

グラフ畳み込みニューラルネットワークを用いた腹部動脈血管名自動命名の初期検討

日比裕太, 林雄一郎, 北坂孝幸, 伊東隼人, 小田昌宏, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集 page： OP5-11 2019.7

移学習を用いた腹部 thick-slice CT 像における多臓器領域の自動抽出の初期検討

申忱, ロスホルガー, 林　雄一郎, 小田紘久, 小田昌宏, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集 page： OP4-15 2019.7

深層学習を用いた腹腔鏡手術動画像の出血領域自動セグメンテーション

山本翔太, 小田紘久, 林雄一郎, 北坂孝幸, 小田昌宏, 伊藤雅昭, 竹下修由, 森健策

第38回日本医用画像工学会大会予稿 page： OP4-13 2019.7

開腹手術映像における遮蔽物除去システムの VR 化

北坂孝幸, 伊藤幹也, 駒形和哉, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集 page： OP4-10 2019.7

μ CT を用いた改良版 Cycle-GAN による臨床用 CT 像の超解像処理

鄭通, 小田紘久, 守谷享泰, 杉野貴明, 中村彰太, 小田昌弘, 森雅樹, 高畠博嗣, 名取博, 森健策

第38回日本医用画像工学会大会予稿集 page： OP4-02 2019.7

小児腸閉塞患者の CT 像における CycleGAN を用いた電子洗浄手法の検討

西尾光平, 小田紘久, 千馬耕亮, 北坂孝幸, 伊東隼人, 小田昌宏, 檜顕成, 内田広夫, 森健策

第38回日本医用画像工学会大会予稿集 page： OP3-20 2019.7

腹腔鏡動画像からの Fully Convolutional Network による血管領域抽出

盛満慎太郎, 小澤　卓也, 北坂孝幸, 林雄一郎, 小田昌宏, 伊藤雅昭, 竹下修由, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集 page： OP3-12 2019.7

Generative Adversarial Frameworks を用いた腹部 CT 像における非造影像からの造影像の推定

小田昌宏, 隈丸加奈子, 青木茂樹, 森健策

第38回日本医用画像工学会大会予稿集 page： OP3-07 2019.7

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Papers - MORI, Kensaku