Faculty Profiles - KIMURA, Hiroshi

Papers - KIMURA, Hiroshi

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Fatal Varicella Infection in a Girl with Systemic Lupus Erythematosus after Oral Acyclovir Prophylaxis. Reviewed

Hirose I, Ymamaguchi H, Inagaguma D, Ono K, Shimada S, Kawada J, Shiraki K, Kimura H.

Eur J Pediatr Vol. 165 page： 280-1 2006

Analysis of Gene Expression Profiles byOligonucleotide Microarray in Children with Influenza. Reviewed

Kawada J,Kimura H , Kamachi Y, Nishikawa K, Taniguchi M, Nagaoka K, Kurahashi H, Kojima S, Morishima T.

J Gen Virol Vol. 87 page： 1677-1683 2006

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

インフルエンザに対する宿主反応のメカニズムを明らかにするために,マイクロアレイを用い,インフルエンザ罹患小児末梢血中の遺伝子発現を網羅的解析した.発現亢進していた遺伝子群は,免疫反応遺伝子群に属するものが多く,インターフェロン制御遺伝子が強く発現亢進していた.熱性痙攣群では,痙攣の無かった群に比べ,22遺伝子の発現が亢進し5つの遺伝子が発現減弱していた.

Association of virus infected-T cell in severe hepatitis caused by primary Epstein-Barr virus infection. Reviewed

Hara S, Hoshino Y, Naitou T, Nagano K, Iwai M, Suzuki K, Yamamoto K, Nagasaka T, Morishima T, Kimura H.

J Clinical Virol Vol. 35 page： 250-256 2006

Chronic Active Epstein-Barr Virus Infection Invited

Kimura H

New Development in Epstein-Barr Virus Research page： 55-70 2006

Chronic active Epstein-Barr virus infection with dilatation of the Valsalva sinus. Reviewed

Sato Y, Tsuboi T, Mikami T, Kurosawa H, Kanou K, Sugita K, Kimura H , Nagasaka T, Imashyuku S, Eguchi M.

Pediatr Int Vol. 48 page： 643-645 2006

Rapid detection of Epstein-Barr virus DNA by loop-mediated isothermal amplification method. Reviewed

Iwata S, Shibata Y , Kawada J, Hara S, Nishiyama Y, Morishima T, Ihira M, Yoshikawa T, Asano Y, Kimura H .

J Clin Virol Vol. 37 page： 128-133 2006

Pathogenesis of chronic active Epstein-Barr virus infection: Is this an infectious disease, lymphoproliferative disorder, or immunodeficiency? Reviewed

Kimura H.

Rev Med Virol Vol. 16 page： 251-261 2006

Quantitative analysis of herpesvirus load in the lymph nodes of patients with histiocytic necrotizing lymphadenitis using a real-time PCR assay. Reviewed

Maeda N et al,

Diagnostic Molecular Pathology Vol. 15 page： 49-55 2006

Clonality Analysis by Sequence Variation of the Latent Membrane Protein 1 Gene in Patients with Chronic Active Epstein ?Barr Virus Infection. Reviewed

Shibata Y,Hoshino Y, Hara S, Yagasaki H, Kojima S, Nishiyama Y, Morishima M, Kimura H .

J Med Virol Vol. 78 page： 770-779 2006

Evaluation of Apoptosis in Epstein-Barr Virus-Associated Haemophagocytic Lymphohistiocytosis. Reviewed

Kawada J, Kimura H , Shibata Y, Hara S, Hoshino Y, Kojima S, Nishikawa K, Morishima T.

J Mel Virol Vol. 17 ( 78 ) page： 400-407 2006

*Differences between T cell-type and natural killer cell-type chronic active Epstein-Barr virus infection. Reviewed

Kimura H, Hoshino Y, Hara S, Sugaya N, Kawada J, Shibata Y, Kojima S, Nagasaka T, Kuzushima K, Morishima T.

J Infect Dis Vol. 191 page： 531-539 2005

Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)

慢性活動性EBウイルス感染症はEBウイルスがT細胞もしくはNK細胞に感染することによって生じる難治性疾患である.本疾患の発症病理を解明するために,T細胞感染群,NK細胞感染群について,ウイルス学・免疫学的な解析を行った.

Virological aspects of Epstein-Barr virus infections. Reviewed

Yamashita N, Kimura H, Morishima T.

Acta Med Okayama. Vol. 59 page： 239-46 2005

Proposed guidelines for diagnosing chronic active epstein-barr virus infection Reviewed

Okano M, Kawa K, Kimura H, Yachie A, Wakiguchi H, Ohga S, Maeda M, Kanegane H, Imai S, Tsuchiya S, Morio T, Mori M, Yokota S, Imashuku S.

Am J Hematol Vol. 80 page： 64-9 2005

Drug-Induced Hypersensitivity Syndrome due to Mexiletine Associated with Human Herpes Virus 6 and Cytomegalovirus Reactivation. Reviewed

Sekiguchi A, Kashiwagi T, Ishida-Yamamoto A, Takahahi H, Hashimoto Y, Kimura H, Tohyama M, Hashimoto K, Iizuka H.

J Dermatol Vol. 32 page： 278-281 2005

Fatal natural killer cell lymphoma arising in a patient with a crop of Epstein-Barr virus-associated disorders. Reviewed

Nitta Y, Iwatsuki K, Kimura H, Kojima S, Morishima T, Tsuji K, Oono T.

Eur J Dermatol Vol. 15 page： 503-506 2005

Ganciclovir therapy in congenital cytomegalovirus infection in six infants. Reviewed

Tanaka-Kitajima N, Sugaya N, Futatani T, Kanegane H, Suzuki C, Oshiro M, Hayakawa M, Futamura M, Morishima T, Kimura H.

Pediatr Infect Dis J Vol. 24 page： 782-785 2005

Rapid detection of herpes simplex virus DNA in cerebrospinal fluid: comparison between loop-mediated isothermal amplification and real-time PCR. Reviewed

Kimura H, Ihira M, Enomoto Y, Kawada J, Ito Y, Morishima T, Yoshikawa T, Asano Y.

Med Microbiol Immunol Vol. 194 page： 181-185 2005

Association of cytomegalovirus with infantile hepatitis. Reviewed

Shibata Y, Kitajima N, Kawada J, Sugaya N, Nishikawa K, T Morishima T, Kimura H.

Microbiol Immunol Vol. 49 page： 771-777 2005

Congenital Cytomegalovirus Infection Diagnosed by Polymerase Chain Reaction With the Use of Preserved Umbilical Cord. Reviewed

Kakizawa H, Okumura A, Suzuki Y, Natsume J, Kimura H, Negoro T, Watanabe K.

Pediatr Infect Dis J Vol. 24 page： 653-654 2005

Herpes simplex virus type 1 UL51 protein is involved in maturation and egress of virus particles. Reviewed

Nozawa N, Kawaguchi Y, Tanaka M, Kato A, Kimura H, Nishiyama Y.

J Virol Vol. 79 page： 6947-6956 2005

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Papers - KIMURA, Hiroshi