研究者詳細 - 橋川　和信

論文 - 橋川　和信

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Complications in Salvage Surgery for Nasal and Paranasal Malignant Tumors Involving the Skull Base 査読有り国際誌 Open Access

Teshima Masanori, Shinomiya Hirotaka, Otsuki Naoki, Kimura Hidehito, Taniguchi Masaaki, Hashikawa Kazunobu, Kohmura Eiji, Nibu Ken-ichi

JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE 79 巻 ( 3 ) 頁： 224 - 228 2018年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Neurological Surgery, Part B: Skull Base

Objective Nasal and paranasal malignant tumors invading the skull base are rare and poorly studied. We evaluated postoperative complications in patients undergoing salvage surgery for such tumors. Design Retrospective study. Setting Kobe University Hospital. Participants Among 48 patients who underwent surgery for tumors involving the skull base between 1993 and 2015, 21 patients had squamous cell carcinoma, 13 had olfactory neuroblastoma, 5 had adenocarcinoma, 2 had sarcoma, 2 had adenoid cystic carcinoma, and 1 each had malignant melanoma, poorly differentiated carcinoma, undifferentiated carcinoma, myoepithelial carcinoma, and malignant peripheral nerve sheath tumor. Prior to skull base surgery, radiotherapy, chemoradiotherapy (CRT), particle radiotherapy, chemotherapy, or surgery were applied in 3, 15, 4, 5, and 3 patients, respectively. Main Outcome Measures Main outcome measures were postoperative complications in patients who underwent skull base surgery after concomitant CRT and/or particle therapy. Results Major postoperative complications were observed in 14 surgical procedures (29%; 2 patients with cerebral herniation, 3 with cerebrospinal fluid leakages, 3 with meningitis, 1 with hydrocephalus, 6 with epidural abscesses, 2 with local infections, and 2 with partial flap necrosis). Four patients developed ≥2 complications. One patient died of postoperative lung infarction. Three (16.7%) of 18 patients without prior treatment and 9 (50%) of 18 patients who underwent preoperative radiotherapy/CRT had severe postoperative complications. Two (50%) of four patients treated with particle radiotherapy had postoperative complications. Conclusions CRT or particle radiotherapy were significantly associated with a high risk of severe postoperative complications after skull base surgery. Meticulous care should be taken in patients treated with radiotherapy/particle therapy prior to skull base surgery.

DOI： 10.1055/s-0037-1606382

Web of Science

Scopus

PubMed

Computed Tomographic Evaluation of Posttreatment Soft-Tissue Changes by Using a Lymphedema Scoring System in Patients with Oral Cancer Open Access

Akashi Masaya, Teraoka Shun, Kakei Yasumasa, Kusumoto Junya, Hasegawa Takumi, Minamikawa Tsutomu, Hashikawa Kazunobu, Komori Takahide

LYMPHATIC RESEARCH AND BIOLOGY 16 巻 ( 2 ) 頁： 147 - 153 2018年4月

Ultrasonography-guided Cannula Method for Hyaluronic Acid Filler Injection with Evaluation using Laser Speckle Flowgraphy 査読有り

Iwayama T, Hashikawa K, Osaki T, Yamashiro K, Horita N, Fukumoto T

PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN 6 巻 ( 4 ) 頁： e4776 - e1776 2018年4月

Ultrasonography-guided Cannula Method for Hyaluronic Acid Filler Injection with Evaluation using Laser Speckle Flowgraphy

Iwayama Takanori, Hashikawa Kazunobu, Osaki Takeo, Yamashiro Kenjiro, Horita Nobuyuki, Fukumoto Takeshi

PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN 6 巻 ( 4 ) 頁： e1776 2018年4月

静脈奇形に対する硬化療法におけるオレイン酸エタノールアミンとポリドカノールの比較検討査読有り

倉本康世, 野村正, 江尻浩隆, 川北育子, 櫻井敦, 橋川和信, 寺師浩人

形成外科 61 巻 ( 4号 ) 頁： 450 - 456 2018年4月

腫瘍切除に伴う顔面神経麻痺の予防と治療腫瘍切除後の顔面神経即時再建術の結果に影響を及ぼす因子は何か同一施設・同一術式による連続症例の検討査読有り

橋川和信

Facial Nerve Research 37 巻頁： 11 - 12 2018年2月

Potential role of post-treatment follow-up FDG-PET CT to detect mandibular osteoradionecrosis: A case report 査読有り

AkashiM, WanifuchiS, KusumotoJ, KishimotoM, KakeiY, HashikawaK, KomoriT

Mol Clin Oncol 8 巻 ( 1 ) 頁： 61 - 67 2018年1月

Potential role of post-treatment follow-up FDG-PET CT to detect mandibular osteoradionecrosis: A case report

Akashi Masaya, Wanifuchi Satoshi, Kusumoto Junya, Kishimoto Megumi, Kakei Yasumasa, Hashikawa Kazunobu, Komori Takahide

MOLECULAR AND CLINICAL ONCOLOGY 8 巻 ( 1 ) 頁： 61 - 67 2018年1月

A Novel Method of Noninvasive Monitoring of Free Flaps With Near-Infrared Spectroscopy 査読有り

TakasuH, HashikawaK, NomuraT, SakakibaraS, OsakiT, TerashiH

Eplasty 17 巻頁： e37 2017年12月

Axial four-dimensional computed tomographic images to analyze crosswise differences in protrusive condylar movement in patients who underwent mandibulectomy and free flap reconstruction 査読有り Open Access

Akashi Masaya, Sekitani Toshinori, Ohtsuki Yumi, Kakei Yasumasa, Kusumoto Junya, Hasegawa Takumi, Maeda Michinori, Negi Noriyuki, Hashikawa Kazunobu, Shibuya Yasuyuki, Takahashi Satoru, Komori Takahide

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY 45 巻 ( 11 ) 頁： 1778 - 1783 2017年11月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Cranio-Maxillofacial Surgery

Objective Few studies evaluate condylar movement following mandibular reconstruction. The main objective of this study was to show that axial four-dimensional computed tomography (4DCT) could visualize bilateral protrusive condylar movement directly. We used axial 4DCT images to assess condylar protrusion in patients who underwent mandibular reconstruction. Methods We enrolled seven healthy volunteers (median age 30 years, range 27–38 years) and seven patients (median age 65 years, range 52–80 years), who underwent mandibulectomy (segmental in five, hemi in one, marginal in one) and free flap reconstruction (using the fibula in six and the radial forearm in one). Six study subjects were instructed to masticate a cookie during the 4DCT scan (the seventh made chewing motions). The distance between the most anterior and posterior positions of the bilateral condyles on 4DCT (axial view) images was then measured and compared between controls and patients using the Mann–Whitney U-test. Results The crosswise difference in the distances of condylar protrusion was significantly greater in patients than in the controls. Conclusion Axial 4DCT images can visualize a bilateral condylar protrusive path. Axial 4DCT images for patients who have undergone mandibulectomy and reconstruction may be useful for evaluation of functional movement of condyles.

DOI： 10.1016/j.jcms.2017.08.025

Web of Science

Scopus

PubMed

Literature Review of Criteria for Defining Recipient-Site Infection after Oral Oncologic Surgery with Simultaneous Reconstruction Open Access

Akashi Masaya, Kusumoto Junya, Sakakibara Akiko, Hashikawa Kazunobu, Furudoi Shungo, Komori Takahide

SURGICAL INFECTIONS 18 巻 ( 7 ) 頁： 755 - 764 2017年10月

記述言語：英語出版者・発行元：Surgical Infections

Background: The lack of uniformity of criteria for defining recipient-site infection after oral oncologic surgery with simultaneous reconstruction is problematic despite numerous studies on this issue. This study aimed to investigate the difference in the criteria for defining recipient-site infection after oral oncologic surgery with reconstruction. Methods: A Medline search was performed via PUBMED using the following combinations of key terms that were tagged in the title, abstract, or both: "surgical site infection-head neck," "surgical site infection-oral cancer," "antibiotic prophylaxis-head neck," and "surgical site infection-oral carcinoma." Search results were filtered between 2005 and 2017. Articles in which there was no mention of the criteria for definition of surgical-site infection were excluded. Results: The number of articles that met the inclusion criteria was 24. The lack of uniformity in the criteria for defining recipient-site infection in each article appeared to be attributable mainly to differences in whether an orocutaneous fistula and superficial incisional infection were regarded as recipient-site infection. Conclusion: Reconsideration of the categorization of orocutaneous fistula as infection, regardless of the etiology, and differentiation of superficial and deep incisional infections are necessary for correct assessment of recipient-site infection in oral oncologic surgery.

DOI： 10.1089/sur.2017.101

Web of Science

Scopus

PubMed

色素レーザー照射後に潰瘍を生じた乳児血管腫症例の検討査読有り

野村正, 江尻浩隆, 森脇綾, 岩山隆憲, 榊原俊介, 高須啓之, 石椛寛芳, 長谷川泰子, 橋川和信, 寺師浩人

日本レーザー医学会誌 38 巻 ( 3号 ) 頁： 315 2017年10月

Rhinoplasty via the midface degloving approach for nasal deformity due to nasal polyps: A case report of Woakes’ syndrome 査読有り

Ueda M., Hashikawa K., Iwayama T., Terashi H.

Oral and Maxillofacial Surgery Cases 3 巻 ( 3 ) 頁： 64 - 69 2017年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Oral and Maxillofacial Surgery Cases

Nasal polyps are inflammatory proliferative tumors arising from the mucosa of the nasal cavity and paranasal sinuses. Although many cases concerning nasal polyps have been reported, those involving external nasal deformities are rare. We report a case of nasal polyposis filling the nasal cavity and paranasal sinuses, leading to external nasal and facial deformities. The condition above is known as Woakes’ syndrome, which is characterized by severe recurrent nasal polyps with deformity of the nasal pyramid, leading to broadening of the nose. We performed nasal osteotomy and facial bone-shaving via the midface degloving approach, which improved the patient's facial appearance.

DOI： 10.1016/j.omsc.2017.05.001

Scopus

Computed Tomographic Evaluation of Posttreatment Soft-Tissue Changes by Using a Lymphedema Scoring System in Patients with Oral Cancer 査読有り Open Access

AkashiM, TeraokaS, KakeiY, KusumotoJ, HasegawaT, MinamikawaT, HashikawaK, KomoriT

Lymphat Res Biol 2017年7月

【頭頸部動静脈奇形の最新治療】動静脈奇形に対する手術療法 nidusを見極めるわれわれの試み査読有り

野村正, 江尻浩隆, 櫻井敦, 川北育子, 橋川和信, 寺師浩人

形成外科 60 巻 ( 6号 ) 頁： 649 - 660 2017年6月

膝窩リンパ節転移を認めた母趾悪性黒色腫の1例査読有り

北川敬之, 野村正, 橋川和信, 藤原進, 田島翔子, 錦織千佳子, 寺師浩人

Skin Cancer 31 巻 ( 3号 ) 頁： 233 - 237 2017年3月

Upregulated Expression of Transient Receptor Potential Cation Channel Subfamily V Receptors in Mucosae of Patients with Oral Squamous Cell Carcinoma and Patients with a History of Alcohol Consumption or Smoking 査読有り Open Access

Sakakibara Akiko, Sakakibara Shunsuke, Kusumoto Junya, Takeda Daisuke, Hasegawa Takumi, Akashi Masaya, Minamikawa Tsutomu, Hashikawa Kazunobu, Terashi Hiroto, Komori Takahide

PLOS ONE 12 巻 ( 1 ) 頁： e0169723 2017年1月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：PLoS ONE

Objectives Transient receptor potential cation channel (subfamily V, members 1±4) (TRPV1±4) are expressed in skin and neurons and activated by external stimuli in normal mucosae of all oral cavity sites. The oral cavity is exposed to various stimuli, including temperature, mechanical stimuli, chemical substances, and changes in pH, and, notably, the risk factors for oncogenic transformation in oral squamous epithelium are the same as the external stimuli received by TRPV1±4 receptors. Hence, we examined the relationship between oral squamous cell carcinoma (SCC) and TRPV1±4 expression. Materials and Methods Oral SCC patients (n = 37) who underwent surgical resection were included in this study. We investigated the expression of TRPV1±4 by immunohistochemical staining and quantification of TRPV1±4 mRNA in human oral mucosa. In addition, we compared the TRPV1±4 levels in mucosa from patients with SCC to those in normal oral mucosa. Results The receptors were expressed in oral mucosa at all sites (tongue, buccal mucosa, gingiva, and oral floor) and the expression was stronger in epithelia from patients with SCC than in normal epithelia. Furthermore, alcohol consumption and tobacco use were strongly associated with the occurrence of oral cancer and were found to have a remarkable influence on TRPV1±4 receptor expression in normal oral mucosa. In particular, patients with a history of alcohol consumption demonstrated significantly higher expression levels. Conclusion Various external stimuli may influence the behavior of cancer cells. Overexpression of TRPV1-4 is likely to be a factor in enhanced sensitivity to external stimuli. These findings could contribute to the establishment of novel strategies for cancer therapy or prevention.

DOI： 10.1371/journal.pone.0169723

A Novel Method of Noninvasive Monitoring of Free Flaps With Near-Infrared Spectroscopy.

Takasu H, Hashikawa K, Nomura T, Sakakibara S, Osaki T, Terashi H

Eplasty 17 巻頁： e37 2017年

Low-Grade Myxofibrosarcoma of the Rectus Abdominus Muscle Infiltrating into Abdominal Cavity: A Case Report. 査読有り国際誌

Tadashi Nomura, Shunsuke Sakakibara, Aya Moriwaki, Teruya Kawamoto, Satoshi Suzuki, Takeshi Ishimura, Kazunobu Hashikawa, Hiroto Terashi

Eplasty 17 巻 ( 2 ) 頁： e6 2017年

記述言語：英語掲載種別：研究論文（学術雑誌）

Objective: Myxofibrosarcoma (MFS) is a relatively rare tumor that is histologically characterized by myxoid stroma and spindle cell proliferation. This tumor most commonly arises as a slow growing, enlarging painless mass in the extremities of elderly patients. Methods: We report a case of a primary, low-grade MFS in the rectus abdominis muscle infiltrating the abdominal cavity of a 75-year-old man. Results: The patient underwent a wide excision of the right abdominal wall mass with a 3-cm surgical margin from the scar due to a biopsy. The tumor infiltrated the urinary bladder, peritoneum, and external iliac vessels. Twenty-six months after the initial operation, he had recurrences in his abdominal wall, urinary bladder, and right iliac vessels. Conclusions: To our knowledge, primary MFS of the muscle in the abdomen has not been documented previously. Although this case was histopathologically classified as a low-grade tumor, it infiltrated the abdominal cavity. The tumor is suspected to have penetrated the abdominal cavity below the linea arcuata, which lacks the posterior sheath of the rectus abdominis muscle; from there, it could easily spread without being blocked by any biological barriers.

PubMed

Low-Grade Myxofibrosarcoma of the Rectus Abdominus Muscle Infiltrating into Abdominal Cavity: A Case Report.

Nomura T, Sakakibara S, Moriwaki A, Kawamoto T, Suzuki S, Ishimura T, Hashikawa K, Terashi H

Eplasty 17 巻頁： e6 2017年

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