研究者詳細 - 橋川　和信

Cardiac metastasis in a living patient with oral cancer 査読有り国際誌

Fujio Hisami, Otsuki Naoki, Horichi Yuto, Yanagisawa Shungaku, Nishio Mari, Teshima Masanori, Shinomiya Hirotaka, Hashikawa Kazunobu, Nibu Ken-ichi

AURIS NASUS LARYNX 46 巻 ( 6 ) 頁： 902 - 906 2019年12月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Auris Nasus Larynx

Cardiac metastasis from head and neck cancers are very rare. Metastases to heart are mostly diagnosed at autopsy, and seldom found while patients are alive. Patients with cardiac metastasis do not present with specific symptoms in the early stages, and diagnosis is often delayed until the disease has advanced significantly. Here, we report a 66-year-old lady who was diagnosed with cardiac metastasis 10 months after surgical resection of oral cancer. She died one month following the discovery of cardiac metastasis. Cardiac metastasis should be considered when unexplained and progressive decline of general health is observed, even in the absence of abnormalities on the electrocardiogram. Early diagnosis may be made by analyzing the chronological changes in the cardiac accumulation of fluorodeoxyglucose during positron emission tomography–computed tomography scan.

DOI： 10.1016/j.anl.2018.10.018

Dental Rehabilitation for Free Fibula Flap-Reconstructed Mandible with Scar Contracture: A Technical Note 査読有り国際誌

Akashi Masaya, Matsumoto Kousuke, Takeda Daisuke, Yamashita Junya, Yatagai Nanae, Hashikawa Kazunobu, Komori Takahide

DENTISTRY JOURNAL 7 巻 ( 3 ) 2019年9月

記述言語：日本語出版者・発行元：Dentistry Journal

Dental rehabilitation with osseointegrated implants in reconstructed mandibles is a common procedure, but the technique still requires improvement, especially in its reliability and technical simplification. We herein report dental rehabilitation of a free fibula-reconstructed mandible with scar contracture. A vestibuloplasty technique with application of a polyglycolic acid (PGA) sheet is described. The implants were inserted into a viable fibula flap with severe scar contracture of the overlying epithelium resulting from vascular instability in skin paddle. Only the fibula periosteum was sutured after implant insertion; exposed surfaces were covered with a combination of PGA sheet and fibrin sealant. The area with PGA sheet coverage gradually healed with moderate contracture. The epithelium around the almost implants became immobilized. The implant-supported removable partial denture with custom titanium bar was acceptable. Dental rehabilitation is possible for reconstructed mandibles with severe scar contracture. Application of a PGA sheet may be useful for vestibuloplasty in patients with reconstructed mandibles.

DOI： 10.3390/dj7030065

Impact of retropharyngeal lymph node dissection in the surgical treatment of hypopharyngeal cancer 査読有り国際誌

Teshima Masanori, Otsuki Naoki, Shinomiya Hirotaka, Morita Naruhiko, Furukawa Tatsuya, Morimoto Koichi, Nakamura Tetsu, Hashikawa Kazunobu, Kiyota Naomi, Sasaki Ryohei, Nibu Ken-ichi

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 41 巻 ( 6 ) 頁： 1738 - 1744 2019年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Head and Neck

Objectives: To evaluate the impact of retropharyngeal lymph node (RPLN) dissection in the surgical treatment of hypopharyngeal cancer. Methods: Between 2007 and 2016, 98 previously untreated patients with pathological diagnosed hypopharyngeal squamous cell carcinoma underwent total pharyngolaryngectomy and bilateral neck dissection at Kobe University Hospital. Bilateral dissection of RPLN was simultaneously performed in all patients. Pharynx was reconstructed with free jejunal transfer in 94 patients and primarily closed in 4 patients. Postoperative chemoradiotherapy was performed in patients with high risk factors including metastasis to RPLN, multiple lymph node metastasis, extranodal invasion, and/or positive/close surgical margins. Results: The median follow-up period was 25 months ranging from 1 to 105 months. RPLN adenopathy was preoperatively identified in 9 patients in FDG-positron emission tomography. All of them had pathologically diagnosed RPLN metastases, which had been controlled in all patients during the observation periods. Among the other 89 patients, 7 patients had RPLN metastasis. The 2-year overall survival rates of the patients with and without RPLN metastasis were 65.7% and 69.8% (P =.61), respectively. Conclusions: In the present study, patients with RPLN metastasis showed equally favorable oncological outcome compared with patients without RPLN metastasis. At least, ipsilateral RPLN dissection should be considered in the surgical treatment of advanced hypopharyngeal cancer and multiple neck lymph node metastasis regardless of primary subsite.

DOI： 10.1002/hed.25608

Long-Term Effects on Volume Change in Musculocutaneous Flaps after Head and Neck Reconstruction

Sakakibara Akiko, Kusumoto Junya, Sakakibara Shunsuke, Hasegawa Takumi, Akashi Masaya, Minamikawa Tsutomu, Furudoi Shungo, Hashikawa Kazunobu, Komori Takahide

JOURNAL OF RECONSTRUCTIVE MICROSURGERY 35 巻 ( 4 ) 頁： 235 - 243 2019年5月

A Novel Plastic Surgical Technique for Treating Congenital Entropion in Asians. 国際誌

Iwayama T, Hashikawa K, Fukumoto T

Plastic and reconstructive surgery. Global open 7 巻 ( 4 ) 頁： e2122 2019年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Plastic and Reconstructive Surgery - Global Open

Congenital entropion is an ocular condition involving malpositioning of the eyelid, which can result in ocular pain, conjunctival epiphora, or photophobia. Noninvasive treatment is effective in some cases; however, surgical treatment is indicated when keratitis and ocular irritating symptoms occur. There is no consensus regarding the most appropriate surgical technique. Moreover, some patients complain of changes in their appearance or unwanted incision scars after surgery. In particular, individuals with certain types of Asian heritage exhibit a lower eyelid morphology that differs from that of white individuals, caused by orbital fat locational difference. Subciliary muscle bulges cause swelling in the lower eyelid called Namidabuluro and are considered to create a youthful and beautiful appearance in Asians. Accordingly, some Asian individuals tend to be sensitive about changes to the appearance of the lower eyelid. To our knowledge, no report has yet described changes to Namidabukuro during congenital entropion repair in Asians. We describe a novel surgical technique for congenital entropion repair with the creation of cosmetically natural Namidabuluro in an East Asian cohort. The study included 8 lower eyelids of 4 Japanese female patients. Scarring was not noticeable in any of the 4 cases. Eversion of the cilia and the creation of cosmetically natural Namidabuluro were accomplished in all cases. There has been no case of recurrence yet. The novel surgical technique we developed enables not only the treatment of congenital entropion but also the creation of cosmetically acceptable Namidabuluro, resulting in increased patient satisfaction.

DOI： 10.1097/GOX.0000000000002122

Two cases of debulking surgery for lower limb diffuse plexiform neurofibroma with transcatheter arterial embolisation

Two cases of debulking surgery for lower limb diffuse plexiform neurofibroma with transcatheter arterial embolisation 査読有り

Kitano D, Osaki T, Nakasone M, Nomura T, Hashikawa K, Terashi H

Int J Surg Case Rep 55 巻頁： 132 - 135 2019年1月

Kitano Daiki, Osaki Takeo, Nakasone Mika, Nomura Tadashi, Hashikawa Kazunobu, Terashi Hiroto

INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS 55 巻頁： 132 - 135 2019年

悪性腫瘍切除後顔面再建のストラテジー－とくに比較的大きな全層欠損について－

橋川和信

Ｓｋｉｎ　Ｃａｎｃｅｒ 34 巻 ( 2 ) 頁： 78 - 82 2019年

退縮後に摘出術を行った耳下腺乳児血管腫の治療経験査読有り

丸口勇人, 野村正, 町田怜央, 村上英毅, 高須啓之, 橋川和信, 寺師浩人

日本形成外科学会会誌 38 巻 ( 12号 ) 頁： 652 - 658 2018年12月

Association between pain severity and clinicohistopathologic findings in the mandibular canal and inferior alveolar nerve of patients with advanced mandibular osteoradionecrosis 査読有り

Hiraoka Yujiro, Akashi Masaya, Wanifuchi Satoshi, Kusumoto Junya, Shigeoka Manabu, Hasegawa Takumi, Hashikawa Kazunobu, Terashi Hiroto, Komori Takahide

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY 126 巻 ( 3 ) 頁： 264 - 271 2018年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Objective: Pain is one of the most problematic symptoms in patients with osteoradionecrosis of the jaws. This study investigated the associations between pain severity and morphologic alterations of the mandibular canal and inferior alveolar nerve, in respective computerized tomography images and resected specimens of mandibular osteoradionecrosis. Study Design: We assessed 14 lesions in 13 patients who underwent segmental mandibulectomy for surgical debridement and simultaneous reconstruction with free fibula flap (1 patient exhibited bilateral lesions). The extent of the mandibular canal bone defect on preoperative coronal computerized tomography images and the number of inferior alveolar nerve fascicles in resected specimens were evaluated. Comparisons were made between the slight pain and extreme pain groups. In most of the patients in the extreme pain group, either mandibular canal bone defects were absent or entire circumferential defects were present; inferior alveolar nerve fascicles were either distinguishable or completely absent in the resected specimens. Results: Although there was no statistically significant association between extreme pain and computerized tomography or histopathologic findings, the histopathologically indistinguishable inferior alveolar nerve fascicles was significantly associated with slight pain. Conclusions: The degree of degeneration of mandibular canal and inferior alveolar nerve may be associated with pain severity in patients with mandibular osteoradionecrosis.

DOI： 10.1016/j.oooo.2018.03.017