Faculty Profiles - HASHIKAWA Kazunobu

再発口腔中咽頭癌に対する遊離皮弁再建に関する検討

Akashi Masaya, Hashikawa Kazunobu, 寺師浩人

日本マイクロサージャリー学会学術集会プログラム・抄録集40周年記念 page： 163 2013.9

One-Stage Umbilicus Reconstruction After Resection of Urachal Cyst Reviewed

Makoto Omori, Kazunobu Hashikawa, Shunsuke Sakakibara, Hiroto Terashi, Shinya Tahara, Yoshie Shibaoka, Kensaku Kimura, Katsuhiro Sano

ANNALS OF PLASTIC SURGERY Vol. 71 ( 1 ) page： 93 - 95 2013.7

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：LIPPINCOTT WILLIAMS & WILKINS

Umbilical reconstruction after total excision of the umbilicus represents a challenging problem for reconstructive surgeons. We describe herein a new method for one-stage umbilical reconstruction after resection of a urachal cyst. This case series included 6 patients, with laparoscopic urachal cyst removal in 5 and conventional transcutaneous surgery in 1. One-stage umbilical reconstruction was performed in all cases. When a conventional transcutaneous approach is indicated, umbilical reconstruction can be undertaken through the same skin incision used for total resection of the urachal cyst. Two triangular flaps were designed just below the umbilical defect. Flaps were rotated 180 degrees and sutured together to form one big triangular flap. This flap was then folded to create the new umbilicus. A deep umbilicus with good shape was constructed in all cases, and all patients were satisfied with the outcome. This method is simple, easy, and produces a natural-looking umbilicus.

DOI： 10.1097/SAP.0b013e318248b830

Osteolipoma in the Glabella: Pathogenesis Associated With Mesenchymal Lipoma-Derived Stem Cells

Osteolipoma in the glabella: pathogenesis associated with mesenchymal lipoma-derived stem cells Reviewed

Makiguchi T, Terashi H, Hashikawa Kazunobu, Yokoo S, Kusaka J

J Craniofac Surg Vol. 24 ( 4 ) page： 1310 - 3 2013.7

Makiguchi Takaya, Terashi Hiroto, Hashikawa Kazunobu, Yokoo Satoshi, Kusaka Junko

JOURNAL OF CRANIOFACIAL SURGERY Vol. 24 ( 4 ) page： 1310 - 1313 2013.7

外傷後に生じたclaw toe変形に対し長趾屈筋腱移行術を施行した1例

高須啓之, Hashikawa Kazunobu, Akashi Masaya, 寺師浩人

日本形成外科学会会誌 Vol. 33 ( 6号 ) page： 469 2013.6

がん切除後下顎骨再建における再建理論「CATコンセプト」臨床症例における実践結果 Reviewed

Hashikawa Kazunobu, Akashi Masaya, 野村正, 寺師浩人

頭頸部癌 Vol. 39 ( 2号 ) page： 166 2013.5

再発口腔中咽頭癌に対する遊離皮弁再建における問題点 Reviewed

Akashi Masaya, Hashikawa Kazunobu, 寺師浩人

頭頸部癌 Vol. 39 ( 2号 ) page： 198 2013.5

当科における照射後再発下咽頭癌に対する救済手術の検討

小松弘和, Morimoto Koichi, 斎藤幹, 大月直樹, Hashikawa Kazunobu, 丹生健一

頭頸部癌 Vol. 39 ( 2号 ) page： 182 2013.5

舌半側切除術後の遊離前腕皮弁再建症例における長期観察結果

Akashi Masaya, Hashikawa Kazunobu, 榊原晶子, 寺師浩人

頭頸部癌 Vol. 39 ( 2号 ) page： 161 2013.5

Supercharged pectoralis major musculocutaneous flap Reviewed

Hashikawa Kazunobu, Terashi Hiroto

J Craniofac Surg Vol. 24 ( 2 ) page： e179 - 82 2013.3

Supercharged Pectoralis Major Musculocutaneous Flap

Makiguchi Takaya, Yokoo Satoshi, Miyazaki Hidetaka, Takayama Yu, Ogawa Masaru, Hashikawa Kazunobu, Terashi Hiroto

JOURNAL OF CRANIOFACIAL SURGERY Vol. 24 ( 2 ) page： E179 - E182 2013.3

Treatment strategy of a huge ameloblastic carcinoma Reviewed

Takaya Makiguchi, Satoshi Yokoo, Hidetaka Miyazaki, Aiko Nobusawa, Masaru Ogawa, Kazunobu Hashikawa, Hiroto Terashi

Journal of Craniofacial Surgery Vol. 24 ( 1 ) page： 287 - 290 2013.1

Language：English Publishing type：Research paper (scientific journal)

Ameloblastic carcinoma is a very rare malignant odontogenic tumor. We report a case of secondary-type ameloblastic carcinoma that extended transversally over almost half of the side of the face. Malignant transformation and identification of the malignant region in the large tumor were achieved using L-3-[F]fluoro-α-methyltyrosine (FAMT)-positron emission tomography (PET)
FAMT is transported into cancer cells by L-type amino acid transporter 1 and shows high specificity for malignant tumors. The malignant region determined by microscopic evaluation of resected samples was similar to the region showing high FAMT uptake in PET. Using preoperative FAMT-PET and magnetic resonance imaging, we were able to achieve total resection of the very large tumor, while avoiding excessive resection that could cause severe functional loss or a poor aesthetic facial appearance. We used a modified Weber-Fergusson incision along the nasolabial fold to the labiajugal fold and reconstruction with a pectoralis major muscle flap, and this gave a good aesthetic outcome. Safe surgical resection was possible because preoperative three-dimensional computed tomography angiography was used to identify the position of the main trunk of the external carotid artery, which was closely aligned with the tumor in a posterior direction in the infratemporal fossa region. Copyright © 2013 by Mutaz B. Habal, MD.

DOI： 10.1097/SCS.0b013e3182710311

Comparison of reinnervation for preservation of denervated muscle volume with motor and sensory nerve: An experimental study Reviewed

上顎切除後に遊離皮弁と顎義歯による再建を併用した症例の臨床的検討 Reviewed

Shibuya Yasuyuki, Minamikawa Tsutomu, Yokoo Satoshi, Hashikawa Kazunobu, Komori Takahide

顎顔面補綴 Vol. 35 ( 2号 ) page： 83 - 91 2012.12

神経端側縫合の将来展望端側神経縫合を利用した腫瘍切除後顔面神経即時再建ループ型神経移植連続10症例の検討 Reviewed

Hashikawa Kazunobu, 榊原俊介

Facial Nerve Research Vol. 32 page： 26 - 28 2012.11

顔面神経再建方法の分類と呼称について「ジャンプグラフト」「クロスリンク」 Reviewed

Hashikawa Kazunobu

Facial Nerve Research Vol. 32 page： 38 - 40 2012.11

Makoto Omori, Shunsuke Sakakibara, Kazunobu Hashikawa, Hiroto Terashi, Shinya Tahara, Daisuke Sugiyama

JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY Vol. 65 ( 7 ) page： 943 - 949 2012.7

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：ELSEVIER SCI LTD

Prevention of the atrophy of denervated muscles is essential for a good outcome in facial contouring and oral reconstruction. In this study, we compared the effectiveness of end-to-end and end-to-side neurorrhaphy of the motor nerve, and end-to-end neurorrhaphy of the sensory nerve, all of which are frequently used in such reconstruction for the prevention of muscle atrophy.
Wistar rats were divided into four groups: group 1, motor nerve division of semimembranosus without repair; group 2, motor nerve division and end-to-end coaptation to the saphenous nerve; group 3, motor nerve division and end-to-side coaptation to the sciatic nerve; and group 4, motor nerve division and end-to-end repair.
Measurement of semi-membranosus volume, histological evaluation and staining of neuromuscular junctions that were carried out 3 months postoperatively revealed that muscle volume preservation was larger in groups 3 and 4 than in the other two groups (p < 0.05), but slightly superior in group 4 (p < 0.05). There was no statistical difference between groups 2 and 1; histologically, muscle architecture was better preserved in group 2 than in group 1; reactivation of the neuromuscular junctions was observed in all except group 1.
End-to-side repair of motor nerves is one of the better options for the preservation of muscle volume when end-to-end nerve repair is not indicated. Sensory protection may also provide some advantages in the preservation of muscle volume. (C) 2012 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

DOI： 10.1016/j.bjps.2012.01.018

Intractable skin ulcerations associated with ion beam therapy

【下肢～足切断術の新しいアプローチ】趾切断時におけるfillet toe flapの利用 Invited Reviewed

Sakakibara Shunsuke, Terashi Hiroto, Sakurai Sayuri, Hashikawa Kazunobu, Tahara Shinya

創傷 Vol. 3 ( 3号 ) page： 123 - 128 2012.7

Shibaoka Y., Hashikawa K., Sarayama Y., Niwa Y., Terashi H., Omori M., Murakami M., Tahara S.

Japanese Journal of Plastic Surgery Vol. 55 ( 5 ) page： 527 - 537 2012.5

Language：Japanese Publisher：Japanese Journal of Plastic Surgery

Ion beam therapy has lately attracted considerable attention as an effective means for beating cancers. Ion beam experts say that it produces less harmful side effects than regular radiation because of its physical features. Sometimes, however, it induces severe skin damage as a side effect. We experienced seven cases of intractable ulcerations associated with ion beam therapy. Original diseases of our cases are composed of three hepatocellular carcinomas, three soft tissue sarcomas, one squamous cell carcinoma in the head and neck region. From these seven cases, we found two important clinical features of the ulcerations due to ion beam. First, severe skin necrosis or ulcerations occur frequently when cancers are located shallowly in the body, for instance hepatocellular carcinoma and soft tissue sarcomas in the extremities. Second, the outbreak of ulceration after ion beam therapy is much earlier than that of chronic ulcerations after regular radiation therapy. Conservative therapy is not effective to cure the ulcerations. We should achieve sufficiently deep debridement and reconstruct the defect by a flap rich in blood supply.