Faculty Profiles - SUGANAMI Takayoshi

Papers - SUGANAMI Takayoshi

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Upregulation of cancer-associated gene expression in activated fibroblasts in a mouse model of non-alcoholic steatohepatitis Open Access

Asakawa Masahiro, Itoh Michiko, Suganami Takayoshi, Sakai Takeru, Kanai Sayaka, Shirakawa Ibuki, Yuan Xunmei, Hatayama Tomomi, Shimada Shu, Akiyama Yoshimitsu, Fujiu Katsuhito, Inagaki Yutaka, Manabe Ichiro, Yamaoka Shoji, Yamada Tetsuya, Tanaka Shinji, Ogawa Yoshihiro

SCIENTIFIC REPORTS Vol. 9 ( 1 ) page： 19601 2019.12

Smart Microneedle Fabricated with Silk Fibroin Combined Semi interpenetrating Network Hydrogel for Glucose-Responsive Insulin Delivery

Chen Siyuan, Matsumoto Hiroko, Moro-oka Yuki, Tanaka Miyako, Miyahara Yuji, Suganami Takayoshi, Matsumoto Akira

ACS BIOMATERIALS SCIENCE & ENGINEERING Vol. 5 ( 11 ) page： 5781 - 5789 2019.11

Evaluation of hepatic function using dynamic contrast-enhanced magnetic resonance imaging in melanocortin 4 receptor-deficient mice as a model of nonalcoholic steatohepatitis

Yamada Tomomi, Kashiwagi Yuto, Rokugawa Takemi, Kato Hideaki, Konishi Haruyo, Hamada Tadateru, Nagai Ryohei, Masago Yusaku, Itoh Michiko, Suganami Takayoshi, Ogawa Yoshihiro, Abe Kohji

MAGNETIC RESONANCE IMAGING Vol. 57 page： 210 - 217 2019.4

Microneedle-Array Patch Fabricated with Enzyme-Free Polymeric Components Capable of On-Demand Insulin Delivery

Chen Siyuan, Matsumoto Hiroko, Moro-oka Yuki, Tanaka Miyako, Miyahara Yuji, Suganami Takayoshi, Matsumoto Akira

ADVANCED FUNCTIONAL MATERIALS Vol. 29 ( 7 ) 2019.2

Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis Open Access

Goto Toshihiro, Itoh Michiko, Suganami Takayoshi, Kanai Sayaka, Shirakawa Ibuki, Sakai Takeru, Asakawa Masahiro, Yoneyama Toshihiro, Kai Toshihiro, Ogawa Yoshihiro

SCIENTIFIC REPORTS Vol. 8 ( 1 ) page： 8157 2018.5

Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors. Open Access

Chiyonobu N, Shimada S, Akiyama Y, Mogushi K, Itoh M, Akahoshi K, Matsumura S, Ogawa K, Ono H, Mitsunori Y, Ban D, Kudo A, Arii S, Suganami T, Yamaoka S, Ogawa Y, Tanabe M, Tanaka S

The American journal of pathology Vol. 188 ( 5 ) page： 1213 - 1224 2018.5

Molecular mechanism of obesity-induced 'metabolic' tissue remodeling. Open Access

Tanaka M, Itoh M, Ogawa Y, Suganami T

Journal of diabetes investigation Vol. 9 ( 2 ) page： 256 - 261 2018.3

Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH Open Access

Shiba Kumiko, Tsuchiya Kyoichiro, Komiya Chikara, Miyachi Yasutaka, Mori Kentaro, Shimazu Noriko, Yamaguchi Shinobu, Ogasawara Naomi, Katoh Makoto, Itoh Michiko, Suganami Takayoshi, Ogawa Yoshihiro

SCIENTIFIC REPORTS Vol. 8 ( 1 ) page： 2362 2018.2

CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis. Open Access

Itoh M, Suganami T, Kato H, Kanai S, Shirakawa I, Sakai T, Goto T, Asakawa M, Hidaka I, Sakugawa H, Ohnishi K, Komohara Y, Asano K, Sakaida I, Tanaka M, Ogawa Y

JCI insight Vol. 2 ( 22 ) 2017.11

Synthetic "smart gel" provides glucose-responsive insulin delivery in diabetic mice. Open Access

Matsumoto A, Tanaka M, Matsumoto H, Ochi K, Moro-Oka Y, Kuwata H, Yamada H, Shirakawa I, Miyazawa T, Ishii H, Kataoka K, Ogawa Y, Miyahara Y, Suganami T

Science advances Vol. 3 ( 11 ) page： eaaq0723 2017.11

Sphingosine 1-Phosphate (S1P) and its receptor S1PR2 regulate ductular reaction in a mouse model of nonalcoholic steatohepatitis

Kato, H; Itoh, M; Suganami, T; Nagai, R; Ishimoto, Y; Hashimoto, K; Morita, A; Yogo, E; Rokushima, M; Ogawa, Y

HEPATOLOGY Vol. 66 page： 1046A - 1047A 2017.10

Hepatocyte death-triggered CD11c-positive macrophage accumulation induces liver fibrosis in a murine model of non-alcoholic steatohepatitis

Itoh, M; Suganami, T; Kanai, S; Shirakawa, I; Sakai, T; Goto, T; Asakawa, M; Hidaka, I; Sakaida, I; Ogawa, Y

HEPATOLOGY Vol. 66 page： 1052A - 1052A 2017.10

The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages. Open Access

Nakajima A, Nakatani A, Hasegawa S, Irie J, Ozawa K, Tsujimoto G, Suganami T, Itoh H, Kimura I

PloS one Vol. 12 ( 7 ) page： e0179696 2017.7

WNK4 is an Adipogenic Factor and Its Deletion Reduces Diet-Induced Obesity in Mice. Open Access

Takahashi D, Mori T, Sohara E, Tanaka M, Chiga M, Inoue Y, Nomura N, Zeniya M, Ochi H, Takeda S, Suganami T, Rai T, Uchida S

EBioMedicine Vol. 18 page： 118 - 127 2017.4

Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis. Open Access

Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, Miyachi Y, Shiba K, Yamaguchi S, Ikeda K, Ochi K, Nakabayashi K, Hata KI, Itoh M, Suganami T, Ogawa Y

Scientific reports Vol. 7 page： 44754 2017.3

Inflammatory responses increase secretion of MD-1 protein. Open Access

Thomas Jennings R, Odkhuu E, Nakashima A, Morita N, Kobayashi T, Yamai I, Tanaka M, Suganami T, Haga S, Ozaki M, Watanabe Y, Nagai Y, Takatsu K, Kikuchi-Ueda T, Ichimonji I, Ogawa Y, Takagi H, Yamazaki T, Miyake K, Akashi-Takamura S

International immunology Vol. 28 ( 10 ) page： 503-512 2016.10

The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages. Open Access

Hachiya R, Shiihashi T, Shirakawa I, Iwasaki Y, Matsumura Y, Oishi Y, Nakayama Y, Miyamoto Y, Manabe I, Ochi K, Tanaka M, Goda N, Sakai J, Suganami T, Ogawa Y

Scientific reports Vol. 6 page： 28845 2016.6

Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice. Open Access

Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake K, Takatsu K

Scientific reports Vol. 6 page： 23097 2016.3

Undernourishment in utero Primes Hepatic Steatosis in Adult Mice Offspring on an Obesogenic Diet; Involvement of Endoplasmic Reticulum Stress. Open Access

Muramatsu-Kato K, Itoh H, Kohmura-Kobayashi Y, Ferdous UJ, Tamura N, Yaguchi C, Uchida T, Suzuki K, Hashimoto K, Suganami T, Ogawa Y, Kanayama N

Scientific reports Vol. 5 page： 16867 2015.11

Integration of transcriptome and methylome analysis of aldosterone-producing adenomas. Open Access

Murakami M, Yoshimoto T, Nakabayashi K, Tsuchiya K, Minami I, Bouchi R, Izumiyama H, Fujii Y, Abe K, Tayama C, Hashimoto K, Suganami T, Hata K, Kihara K, Ogawa Y

European journal of endocrinology Vol. 173 ( 2 ) page： 185-95 2015.8

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Papers - SUGANAMI Takayoshi