Faculty Profiles - SUGANAMI Takayoshi

Papers - SUGANAMI Takayoshi

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Brain lipid profiles and oligodendrocyte gene expression show discordant responses to high-fat diet in Alzheimer's disease mice Open Access

Kawade, N; Komine, O; Sobue, A; Kakimi, C; Tanaka, M; Suganami, T; Shimada, M; Ogi, T; Ikeda, K; Horiuchi, M; Watanabe, S; Saito, T; Yamanaka, K

SCIENTIFIC REPORTS Vol. 16 ( 1 ) 2026.2

Genome-wide CRISPR-Cas9 screen identifies genes conferring Lenvatinib resistance in hepatocellular carcinoma

Zhou, S; Abe, Y; Isomura, H; Tanaka, M; Yamaguchi, R; Suganami, T; Taguchi, A

CANCER SCIENCE Vol. 117 page： 669 - 669 2026.1

Altered glycolipid metabolism during acute kidney injury exacerbates renal inflammation Open Access

Osada, A; Tanaka, M; Sugiura, Y; Yuan, XM; Yamashita, S; Ochi, K; Kohda, H; Ito, A; Go, S; Okajima, T; Kadomatsu, K; Yanagita, M; Furuhashi, K; Maruyama, S; Suganami, T

SCIENTIFIC REPORTS Vol. 16 ( 1 ) page： 147 2025.12

Glucose and insulin responses following streptozotocin administration for the induction of a type 1 diabetes mellitus model in Microminipig

Izumi, M; Hano, K; Kato, T; Hirata, A; Thaw, P; Seki, A; Tanaka, M; Ochi, K; Suganami, T; Kitagawa, H; Takasu, M

JOURNAL OF VETERINARY MEDICAL SCIENCE Vol. 87 ( 10 ) page： 1122 - 1127 2025.10

Potential effects of microglia-vascular interactions during chronic systemic inflammation in the central nervous system of mice with systemic lupus erythematosus

Shindo, M; Tsuji, T; Hartantyo, RY; Saito, Y; Ito, A; Sugio, S; Takeda, I; Suganami, T; Wake, H

NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 87 ( 3 ) page： 509 - 520 2025.8

Transient Dietary Intervention Induces Healthy Adipose Tissue Expansion and Metabolically Healthy Obesity in Mice Open Access

Wada, E; Hosono, H; Tanaka, M; Miyakawa, F; Ochi, K; Kohda, H; Tanno, S; Shimano, R; Ito, A; Kitaura, Y; Ichihara, K; Matsumoto, A; Ogi, T; Satoh-Asahara, N; Murohara, T; Suganami, T

FASEB JOURNAL Vol. 39 ( 14 ) page： e70847 2025.7

Novel cell-to-cell communications between macrophages and fibroblasts regulate obesity-induced adipose tissue fibrosis. Invited Reviewed

Diabetes Vol. 74 ( 7 ) page： 1135 - 1152 2025.7

Lipid metabolism in myeloid cell function and chronic inflammatory diseases

Ito, A; Suganami, T

FRONTIERS IN IMMUNOLOGY Vol. 15 page： 1495853 2025.1

Genome-wide CRISPR-Cas9 screen for the identification of genes modulating lenvatinib resistance in HCC

Zhou, S; Abe, Y; Kajino, T; Isomura, H; Tanaka, M; Yamaguchi, R; Suganami, T; Taguchi, A

CANCER SCIENCE Vol. 116 page： 1363 - 1363 2025.1

Meflin/ISLR is a marker of adipose stem and progenitor cells in mice and humans that suppresses white adipose tissue remodeling and fibrosis

Ishihara, T; Kato, K; Matsumoto, K; Tanaka, M; Hara, A; Shiraki, Y; Morisaki, H; Urano, Y; Ando, R; Ito, K; Mii, S; Esaki, N; Furuhashi, K; Takefuji, M; Suganami, T; Murohara, T; Enomoto, A

GENES TO CELLS Vol. 29 ( 10 ) page： 902 - 920 2024.10

Oya, M; Miyasaka, Y; Nakamura, Y; Tanaka, M; Suganami, T; Mashimo, T; Nakamura, K

CELL METABOLISM Vol. 36 ( 5 ) page： 1044 - 1058.e10 2024.5

Imeglimin Exhibits Novel Anti-Inflammatory Effects on High-Glucose-Stimulated Mouse Microglia through ULK1-Mediated Suppression of the TXNIP-NLRP3 Axis Open Access

Kato, H; Iwashita, K; Iwasa, M; Kato, S; Yamakage, H; Suganami, T; Tanaka, M; Satoh-Asahara, N

CELLS Vol. 13 ( 3 ) 2024.2

Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH Open Access

Itoh, M; Tamura, A; Kanai, S; Tanaka, M; Kanamori, Y; Shirakawa, I; Ito, A; Oka, Y; Hidaka, I; Takami, T; Honda, Y; Maeda, M; Saito, Y; Murata, Y; Matozaki, T; Nakajima, A; Kataoka, Y; Ogi, T; Ogawa, Y; Suganami, T

JOURNAL OF EXPERIMENTAL MEDICINE Vol. 220 ( 11 ) 2023.9

The new findings of disordered BCAA catabolism for metabolic disease

Wada, E; Suganami, T; Kitamura, T

ANNALS OF NUTRITION AND METABOLISM Vol. 79 page： 244 - 244 2023.8

Taxifolin Suppresses Inflammatory Responses of High-Glucose-Stimulated Mouse Microglia by Attenuating the TXNIP-NLRP3 Axis Open Access

Iwasa, M; Kato, H; Iwashita, K; Yamakage, H; Kato, S; Saito, S; Ihara, M; Nishimura, H; Kawamoto, A; Suganami, T; Tanaka, M; Satoh-Asahara, N

NUTRIENTS Vol. 15 ( 12 ) 2023.6

Tissue transglutaminase exacerbates renal fibrosis via alternative activation of monocyte-derived macrophages Open Access

Shinoda, Y; Tatsukawa, H; Yonaga, A; Wakita, R; Takeuchi, T; Tsuji, T; Tanaka, M; Suganami, T; Hitomi, K

CELL DEATH & DISEASE Vol. 14 ( 2 ) page： 136 2023.3

Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84 Open Access

Ohue-Kitano, R; Nonaka, H; Nishida, A; Masujima, Y; Takahashi, D; Ikeda, T; Uwamizu, A; Tanaka, M; Kohjima, M; Igarashi, M; Katoh, H; Tanaka, T; Inoue, A; Suganami, T; Hase, K; Ogawa, Y; Aoki, J; Kimura, I

JCI INSIGHT Vol. 8 ( 2 ) 2023.1

Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and Tumorigenesis Open Access

Inoue, T; Fu, B; Nishio, M; Tanaka, M; Kato, H; Tanaka, M; Itoh, M; Yamakage, H; Ochi, K; Ito, A; Shiraki, Y; Saito, S; Ihara, M; Nishimura, H; Kawamoto, A; Inoue, S; Saeki, K; Enomoto, A; Suganami, T; Satoh-Asahara, N

NUTRIENTS Vol. 15 ( 2 ) 2023.1

Molecular mechanism of crosstalk between immune and metabolic systems in metabolic syndrome Open Access

Hachiya, R; Tanaka, M; Itoh, M; Suganami, T

INFLAMMATION AND REGENERATION Vol. 42 ( 1 ) page： 13 2022.5

FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting

Oyabu, M; Takigawa, K; Mizutani, S; Hatazawa, Y; Fujita, M; Ohira, Y; Sugimoto, T; Suzuki, O; Tsuchiya, K; Suganami, T; Ogawa, Y; Ishihara, K; Miura, S; Kamei, Y

FASEB JOURNAL Vol. 36 ( 2 ) page： e22152 2022.2

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Papers - SUGANAMI Takayoshi