論文 - 中川 優
-
Synthesis, Conformation and PKC isozyme Surrogate Binding of Indolinelactam-Vs, New Conformationally-Restricted Analogues of (-)-Indolactam-V 査読有り
Nakagawa, Y., Irie, K., Komiya, Y., Ohigashi, H. and Tsuda, K.
Tetrahedron 60 巻 頁： 7077-7084 2004年
-
Indolactam and Benzolactam Compounds as New Medical Leads with Binding Selectivity for C1 Domains of Protein Kinase C Isozymes 招待有り 査読有り
Irie, K., Nakagawa, Y. and Ohigashi, H.
Curr. Pharm. Design 10 巻 頁： 1371-1385 2004年
-
Tumor promoter binding of the protein kinase C C1 homology domain peptides of RasGRPs, chimaerins, and Unc13s 査読有り
Irie, K., Masuda, A., Shindo, M., Nakagawa, Y. and Ohigashi, H.
Bioorg. Med. Chem. Lett. 12 巻 頁： 4547-4583 2004年
-
Synthesis and Binding Selectivity of 7- and 15-Decylbenzolactone-V8 for the C1 Domains of Protein Kinase C Isozymes 査読有り
Nakagawa, Y., Irie, K., Yamanaka, N., Ohigashi, H. and Tsuda, K.
Bioorg. Med. Chem. Lett. 13 巻 頁： 3015-3019 2003年
-
Synthesis and PKC Isozyme Surrogate Binding of Lactone Analogues of Benzolactam-V8's 査読有り
Nakagawa, Y., Irie, K., Masuda, A. and Ohigashi, H.
Tetrahedron 58 巻 頁： 2101-2115 2002年
-
Establishment of a binding assay for new medicinal leads with protein kinase C isozyme and C1 domain selectivity 招待有り 査読有り
Irie, K., Nakahara, A., Nakagawa, Y., Ohigashi, H., Shindo, M., Fukuda, H., Konishi, H., Kikkawa, U., Kashiwagi, K. and Saito, N.
Pharmacol. Ther. 93 巻 頁： 271-281 2002年
-
Binding Selectivity of Conformationally Restricted Analogues of (-)-Indolactam-V to the C1 Domains of Protein Kinase C Isozymes 査読有り
Masuda, A., Irie, K., Nakagawa, Y. and Ohigashi, H.
Biosci. Biotechnol. Biochem. 66 巻 頁： 1615-1617 2002年
-
The C4 Hydroxyl Group of Phorbol Esters is Not Necessary for Protein Kinase C Binding 査読有り
Tanaka, M., Irie, K., Nakagawa, Y., Nakamura, Y., Ohigashi, H. and Wender, P. A.
Bioorg. Med. Chem. Lett. 11 巻 頁： 719-722 2001年
-
The Amide Hydrogen of (-)-Indolactam-V and Benzolactam-V8's Plays a Critical Role in Protein Kinase C Binding and Tumor-promoting Activities 査読有り
Nakagawa, Y., Irie, K., Nakamura, Y. and Ohigashi, H.
Bioorg. Med. Chem. Lett. 11 巻 頁： 723-728 2001年
-
Synthesis and Tumor-promoting Activities of 12-Epi-phorbol-12,13-dibutyrate 査読有り
Irie, K., Nakahara, A., Ikawa, Y., Tanaka, M., Nakagawa, Y., Nakamura, Y., Ohigashi, H. and Wender, P. A.
Biosci. Biotechnol. Biochem. 64 巻 頁： 2429-2436 2000年
-
Selective Binding of Tumor Promoters to the Novel PKC C1B Domains 招待有り 査読有り
Irie, K., Nakahara, A., Nakagawa, Y., Ohigashi, H., Shindo, M., Fukuda, H., Konishi, H. and Kikkawa, U.
Peptide Science 2000 頁： 197-200 2000年
-
Selective Binding to the nPKC C1B Domains by Tumor Promoters
Nakagawa, Y. and Irie, K.
Bioscience & Industry 58 巻 頁： 570-571 2000年
-
Synthesis and PKC Isozyme Surrogate Binding of Indothiolactam-V, a New Thioamide Analogue of Tumor Promoting Indolactam-V 査読有り
Nakagawa, Y., Irie, K., Ohigashi, H., Hayashi, H. and Wender, P. A.
Bioorg. Med. Chem. Lett. 10 巻 頁： 2087-2090 2000年
-
Isolation of (-)-14-O-Malonylindolactam-V as a Possible Precursor of (-)-Indolactam-V and (-)-14-O-Acetylindolactam-V from Streptomyces blastmyceticum 査読有り
Irie, K., Tomimatsu, S., Nakagawa, Y., Ohigashi, H. and Hayashi, H.
Biosci. Biotechnol. Biochem. 63 巻 頁： 1669-1670 1999年
-
Synthesis and Biological Activities of (-)-6-n-Octyl-indolactam-V, a New Potent Analogue of the Tumor Promoter (-)-Indolactam-V 査読有り
Nakagawa, Y., Irie, K., Nakamura, Y. and Ohigashi, H.
Biosci. Biotechnol. Biochem. 62 巻 頁： 1568-1573 1998年
-
Biosynthesis of Monoterpenoid Moiety of Teleocidins via the Non-mevalonate Pathway in Streptomyces 査読有り
Irie, K., Nakagawa, Y., Tomimatsu, S. and Ohigashi, H.
Tetrahedron Lett. 39 巻 頁： 7929-7930 1998年
-
Synthesis and Biological Activities of Indolactone-V, the Lactone Analogue of the Tumor Promoter (-)-Indolactam-V 査読有り
Nakagawa, Y., Irie, K., Nakamura, Y., Ohigashi, H. and Hayashi, H.
Biosci. Biotech. Biochem. 61 巻 頁： 1415-1417 1997年
-
Comparison of Chemical Characteristics of the First and Second Cystein-Rich Domains of Protein Kinase Cγ 査読有り
Irie, K., Yanai, Y., Oie, K., Ishizawa, J., Nakagawa, Y., Ohigashi, H., Wender, P. A. and Kikkawa, U.
Bioorg. Med. Chem. 5 巻 頁： 1725-1737 1997年