研究者詳細 - 宮田　聖子

論文 - 宮田　聖子

分割表示 120 件中 61 - 80 件目／全件表示 >>

Impaired cortical oxygenation is related to mood disturbance resulting from three nights of sleep restriction. 査読有り

Miyata S, Noda A, Iwamoto K, Kawano N, Banno M, Tsuruta Y, Noda Y, Ozaki N.

Sleep Biol Rhythms 2015年7月

The effect of habitual physical training on left ventricular function during exercise by three-dimensional echocardiography 査読有り

Kojima MS, Noda A, Miyata S, Kojima J, Hara Y, Minoshima M, Matsushita T, Murohara T

Echocardiography 2015年3月

Smoking acutely impaired endothelial function in healthy college students

Miyata S., Noda A., Ito Y., Iizuka R., Shimokata K.

Acta Cardiologica 70 巻 ( 3 ) 頁： 282 - 285 2015年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Acta Cardiologica

Objective Cigarette smoking has been clearly pointed out as a risk factor for cardiovascular disease. Endothelial dysfunction contributes to the development of cardiovascular disease. Flow-mediated dilation (FMD) has been known as one of the endothelial function markers. We investigated the acute and chronic effects of smoking on endothelial function in college-aged smokers. Methods Eighteen smokers (mean age: 21 ± 1 y) and 14 non-smokers (mean age: 20 ± 1 y) were enrolled in this study. Brachial-ankle pulsed wave velocity (baPWV), systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) were measured using a plethysmograph. Endotheliumdependent FMD was induced by reactive hyperaemia. High-resolution ultrasound with a 7.5-MHz linear array transducer was used to measure the diameter of the right brachial artery. Measurement of baPWV, SBP, DBP, HR, artery diameter, and %FMD was performed in smokers and non-smokers after 10 min bed rest, and after smoking one cigarette in the smokers. The interval between the two measurements was more than 15 minutes. Results There were no significant differences on baPWV, SBP, DBP, HR, baseline brachial artery diameter between smokers and non-smokers. Percent FMD after smoking was significantly lower than that at rest values in smokers (8.7 ± 4.0 vs 5.3 ± 2.4, P < 0.005), although %FMD at rest was not significantly different between smokers and non-smokers. No other markers showed any significant differences between smokers at rest and after smoking. Conclusion Even the smoking of one cigarette dramatically impaired endothelial function, although habitual cigarette smoking did not decrease FMD in young healthy smokers.

DOI： 10.2143/AC.70.3.3080632

Web of Science

Scopus

PubMed

The effects of acute treatment with paroxetine, amitriptyline, and placebo on equilibrium function in healthy subjects: A double-blind crossover trial. 査読有り

Miyata S, Noda A, Iwamoto K, Takahashi M, Hara Y, Kojima J, Iidaka T, Ozaki N.

Int J Psy Clin Pract. 18 巻 ( 1 ) 頁： 32-36 2014年

Effects of a custom-made pillow on sleep and blood pressure circadian rhythm 査読有り

MiyataS, Noda A

J Hypertens 3 巻頁： 183 2014年

睡眠ポリグラフ検査における心電図モニターの役割

宮田聖子, 野田明子

睡眠医療 7 巻頁： 406 - 410 2014年

Effects of Aged Garlic Extract on Left Ventricular Diastolic Function and Fibrosis in a Rat Hypertension Model

Hara Yuki, Noda Akiko, Miyata Seiko, Minoshima Makoto, Sugiurai Mari, Kojima Jun, Takeo Masafumi, Furukawa Mayuko, Cheng Xian Wu, Nagata Kohzo, Murohara Toyoaki

EXPERIMENTAL ANIMALS 62 巻 ( 4 ) 頁： 305-310 2013年10月

Disproportionate change of blood flow between the upper limbs and the lower limbs in healthy young adults during recovery from exercise. 査読有り

Miyata S, Noda A, Nishikimi N, Yamada A, Murohara T, Komori K.

Gazzetta Medica Italiana. 172 巻 ( 3 ) 頁： 131-136 2013年

Comparison of oxygen desaturation patterns in children and adults with sleep-disordered breathing. 査読有り

Hara Y, Noda A, Miyata S, Otake H, Yasuda Y, Okuda M, Koike Y, Nakata S, Nakashima T.

Am J Otolaryngol. 34 巻 ( 5 ) 頁： 537-540 2013年

Poor sleep quality impaired cognitive performance in older adults. 査読有り

Miyata S, Noda A, Iwamoto K, Kawano N, Okuda M, Ozaki N.

J Sleep Res 22 巻 ( 5 ) 頁： 535-541 2013年

Effect of Aged Garlic Extract on Left Ventricular Diastolic Function and Fibrosis in Rats Model of Hypertension. 査読有り

Hara Y, Noda A, Miyata S, Minoshima M, Sugiura M, Kojima J, Otake M, Furukawa M, Cheng XW, Nagata K, Murohara T.

Exp Animal. 62 巻頁： 305-310 2013年

Therapeutic strategies for sleep apnea in patients with hypertension and heart failure 査読有り

Noda A, Miyata S, Yasuda Y

Pulmonary Medicine 2013 巻頁： 814169 2013年

Therapeutic strategies for sleep apnea in hypertension and heart failure. Open Access

Noda A, Miyata S, Yasuda Y

Pulmonary medicine 2013 巻頁： 814169 2013年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Pulmonary Medicine

Sleep-disordered breathing (SDB) causes hypoxemia, negative intrathoracic pressure, and frequent arousal, contributing to increased cardiovascular disease mortality and morbidity. Obstructive sleep apnea syndrome (OSAS) is linked to hypertension, ischemic heart disease, and cardiac arrhythmias. Successful continuous positive airway pressure (CPAP) treatment has a beneficial effect on hypertension and improves the survival rate of patients with cardiovascular disease. Thus, long-term compliance with CPAP treatment may result in substantial blood pressure reduction in patients with resistant hypertension suffering from OSAS. Central sleep apnea and Cheyne-Stokes respiration occur in 30-50% of patients with heart failure (HF). Intermittent hypoxemia, nocturnal surges in sympathetic activity, and increased left ventricular preload and afterload due to negative intrathoracic pressure all lead to impaired cardiac function and poor life prognosis. SDB-related HF has been considered the potential therapeutic target. CPAP, nocturnal O2 therapy, and adaptive servoventilation minimize the effects of sleep apnea, thereby improving cardiac function, prognosis, and quality of life. Early diagnosis and treatment of SDB will yield better therapeutic outcomes for hypertension and HF. © 2013 Akiko Noda et al.

DOI： 10.1155/2013/814169

Open Access

Scopus

PubMed

心房細動と睡眠呼吸障害

宮田聖子, 野田明子

睡眠医療 7 巻頁： 272 - 275 2013年

Rapid eye movement (REM) sleep: New research

Noda A.

Rapid Eye Movement Sleep: New Research 頁： 73-83 2012年3月

The effects of the prone position on the physiological function in healthy students. 査読有り

Miyata S, Noda A, Fujii Y, Maekawa A, Okuda M, Nakazaki C, Otake H, Nakata S, Yasuma F, Koike Y, Shimokata K, Nakashima T, Hinohara S.

Open Gen Intern Med J. 5 巻頁： 9-12 2012年

The effects of the prone position on the physiological function in healthy students. 査読有り

Miyata S, Noda A, Fujii Y, Maekawa A, Okuda M, Nakazaki C, Otake H, Nakata S, Yasuma F, Koike Y, Shimokata K, Nakashima T, Hinohara S

Open Gen Intern Med J 5 巻頁： 9-12 2012年

RELATIONSHIP BETWEEN SLEEP DURATION AND CARDIO-ANKLE VASCULAR INDEX IN HEALTHY YOUNG ADULTS

Noda A., Miyata S.

SLEEP 35 巻頁： A317 - A317 2012年

The ratio of adiponectin to homeostasis model assessment of insulin resistance is a powerful index of each component of metabolic syndrome in an aged Japanese population: results from the KING Study.

Nakatochi M, Miyata S, Tanimura D, Izawa H, Asano H, Murase Y, Kato R, Ichihara S, Naruse K, Matsubara T, Honda H, Yokota M

Diabetes research and clinical practice 92 巻 ( 3 ) 頁： e61 - 5 2011年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Diabetes Research and Clinical Practice

We evaluated the ratio of adiponectin level to homeostasis model assessment of insulin resistance (A/H ratio) as a risk marker for metabolic syndrome (MetS) and each of its components. The A/H ratio may prove to be a powerful index for evaluation of risk for MetS and each of its components. © 2011 Elsevier Ireland Ltd.

DOI： 10.1016/j.diabres.2011.02.029

Web of Science

Scopus

PubMed

Relation of a common variant of the adiponectin gene to serum adiponectin concentration and metabolic traits in an aged Japanese population. Open Access

Tanimura D, Shibata R, Izawa H, Hirashiki A, Asano H, Murase Y, Miyata S, Nakatochi M, Ouchi N, Ichihara S, Yasui K, Yoshida T, Naruse K, Matsubara T, Yokota M

European journal of human genetics : EJHG 19 巻 ( 3 ) 頁： 262 - 9 2011年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：European Journal of Human Genetics

Adiponectin is an adipocyte-derived protein that is down-regulated in obesity-linked disorders. Variants of the adiponectin gene (ADIPOQ) have been shown to affect adiponectin level. We have now examined the relation of polymorphisms of ADIPOQ to adiponectin concentration and to metabolic disorders in the Kita-Nagoya Genomic Epidemiology study, a population-based study of elderly Japanese. The genomic region including ADIPOQ was genotyped for 30 single nucleotide polymorphisms in 500 subjects of a screening population with the use of a fluorescence- or colorimetry-based allele-specific DNA primer-probe assay system. Four polymorphisms were then selected for genotyping in an additional 2797 subjects. Serum adiponectin level was negatively associated with metabolic abnormalities after adjustment for age and sex. The minor alleles of the rs1656930, Ile164Thr, and rs9882205 polymorphisms were associated with a low serum adiponectin level. Whereas the minor alleles of rs1656930 and rs9882205 were common (minor allele frequency of 6.2 and 38.5%, respectively), that of Ile164Thr was rare (0.9%). The minor allele of rs1656930 was positively associated with systolic blood pressure and the prevalence of hypertension. The association of rs1656930 with adiponectin level was replicated in an independent population. A subject with the 164Thr/Thr genotype had an extremely low serum adiponectin level (0.6 g/ml) and the phenotype of metabolic syndrome. Our results suggest that a common variant of ADIPOQ, the minor allele of rs1656930, is associated with hypoadiponectinemia and hypertension. Screening for a common genetic background underlying low adiponectin levels might provide important information for assessment and management of metabolic disorders. © 2011 Macmillan Publishers Limited All rights reserved.

DOI： 10.1038/ejhg.2010.201

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論文 - 宮田 聖子

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論文 - 宮田　聖子