Papers - KIYOI, Hitoshi
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Novel and orally active 5-(1,3,4-oxadiazol-2-yl)pyrimidine derivatives as selective FLT3 inhibitors. Reviewed
Ishida H, Isami S, Matsumura T, Umehara H, Yamashita Y, Kajita J, Fuse E, Kiyoi H, Naoe T, Akinaga S, Shiotsu Y, Arai H.
Bioorg Med Chem Lett. Vol. 18 page： 5472-5477 2008
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Clinical significance of minimal residual disease in patients with t(8;21) acute myeloid leukemia in Japan. Reviewed
Narimatsu H, Iino M, Ichihashi T, Yokozawa T, Hayakawa M, Kiyoi H, Takeo T, Sawamoto A, Iida H, Tsuzuki M, Yanada M, Naoe T, Suzuki R, Sugiura I.
Int J Hematol Vol. 88 2008
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Karyotypically independent clones with del(11q) and trisomy 10 in acute myeloid leukemia: trisomy 10 may appear as an additional change. Reviewed
Gotoh M, Sasaki Y, Iguchi T, Fujimoto H, Kodama A, Kiyoi H, Naoe T, Ohyashiki K.
Int J Hematol Vol. 88 page： 123-124 2008
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Donor cell leukemia after allogeneic peripheral blood stem cell transplantation: a case report and literature review. Reviewed
Murata M, Ishikawa Y, Ohashi H, Terakura S, Ozeki K, Kiyoi H, Naoe T.
Int J Hematol Vol. 88 page： 111-115 2008
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Functional analysis of JAK3 mutations in transient myeloproliferative disorder and acute megakaryoblastic leukaemia accompanying Down syndrome. Reviewed
Sato T, Toki T, Kanezaki R, Xu G, Terui K, Kanegane H, Miura M, Adachi S, Migita M, Morinaga S, Nakano T, Endo M, Kojima S, Kiyoi H, Mano H, Ito E.
Br J Haematol. Vol. 141 page： 681-688 2008
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Mutations of JAK2, JAK3 and GATA1 in acute megakaryoblastic leukemia of Down syndrome. Reviewed Open Access
8. Hama A, Yagasaki H, Takahashi Y, Matsumoto K, Kiyoi H, Kojima S.
Blood Vol. 111 page： 2493-2494 2008
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Clinical characteristics and outcomes in patients with t(8;21) acute myeloid leukemia in Japan. Reviewed
9. Narimatsu H, Yokozawa T, Iida H, Tsuzuki M, Hayakawa M, Takeo T, Iino M, Ichihashi T, Kato C, Sawamoto A, Sao H, Yanada M, Emi N, Kiyoi H, Yamaguchi T, Naoe T, Suzuki R, Sugiura I.
Leukemia Vol. 22 page： 432-434 2008
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Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy. Reviewed Open Access
Abe A, Minami Y, Hayakawa F, Kitamura K, Nomura Y, Murata M, Katsumi A, Kiyoi H, Jamieson CH, Wang JY, Naoe T.
Int J Hematol Vol. 88 page： 471-475 2008
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Clinical features and outcome of T-lineage acute lymphoblastic leukemia in adults: A low initial white blood cell count, as well as a high count predict decreased survival rates. Reviewed
Yanada M, Jinnai I, Takeuchi J, Ueda T, Miyawaki S, Tsuzuki M, Hatta Y, Usui N, Wada H, Morii T, Matsuda M, Kiyoi H, Okada M, Honda S, Miyazaki Y, Ohno R, Naoe T.
Leukemia Res Vol. 31 2007
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LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). Reviewed
Imagama S, Abe A, Suzuki M, Hayakawa F, Katsumi A, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. Vol. 78 2007
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FLT3 regulates beta-catenin tyrosine phosphorylation, nuclear localization, and transcriptional activity in acute myeloid leukemia cells. Reviewed
Kajiguchi T, Chung EJ, Lee S, Stine A, Kiyoi H, Naoe T, Levis MJ, Neckers L, Trepel JB.
Leukemia Vol. 21 2007
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Clinical characteristics and outcomes in patients with t(8;21) acute myeloid leukemia in Japan. Reviewed
Narimatsu H, Yokozawa T, Iida H, Tsuzuki M, Hayakawa M, Takeo T, Iino M, Ichihashi T, Kato C, Sawamoto A, Sao H, Yanada M, Emi N, Kiyoi H, Yamaguchi T, Naoe T, Suzuki R, Sugiura I.
Leukemia Vol. 21 2007
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High incidence of secondary failure of platelet recovery after autologous and syngeneic peripheral blood stem cell transplantation in acute promyelocytic leukemia. Reviewed
Narimatsu H, Emi N, Kohno A, Iwai M, Yanada M, Yokozawa T, Saito S, Shimada K, Kiyoi H, Naoe T, Yamamoto K, Morishita Y.
Bone Marrow Transplant Vol. 40 2007
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Prognostic analysis of aberrant somatic hypermutation of RhoH gene in diffuse large B cell lymphoma. Reviewed
Hiraga J, Katsumi A, Iwasaki T, Abe A, Kiyoi H, Matsushita T, Kinoshita T, Naoe T.
Leukemia Vol. 21 2007
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Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice. Reviewed
Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T.
Leukemia Vol. 21 page： 136 2007
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Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. Reviewed
Okamoto M, Hayakawa F, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T.
Leukemia Vol. 21 page： 403 2007
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JAK3 mutations occur in acute megakaryoblastic leukemia both in Down syndrome children and non-Down syndrome adults. Reviewed
Kiyoi H, Yamaji S, Kojima, Naoe T.
Leukemia Vol. 21 page： 574 2007
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Epegenetic regulation of CD20 protein expression in a novel B-cell lymphoma cell line, RRBL1, established from a patient treated repeatedly with Rituximab-containing chemotherapy. Reviewed
Tomita A, Hiraga J, Kiyoi H, Ninomiya M, Sugimoto T, Ito M, Kinoshita T, Naoe T.
Int J Hematol Vol. 84 2007
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A novel FLT3 inhibitor FI-700 selectively suppress the growth of leukemia cells with FLT3 mutations. Reviewed
Kiyoi H, Shiotsu Y, Ozeki K, Yamaji S, Kosugi H, Umehara H, Arai H, Ishii K, Akinaga S, Naoe T.
Clin Cancer Res Vol. 13 page： 4575-4582 2007
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Successful second cord blood transplantation using fludarabine and cyclophosphamide as a preparative regimen for graft rejection following reduced-intensity cord blood transplantation. Reviewed
Mizutani E, Narimatsu H, Murata M, Tomita A, Kiyoi H, Naoe T.
Bone Marrow Tranaplant Vol. 32 2007