Faculty Profiles - OKAJIMA, Tetsuya

Papers - OKAJIMA, Tetsuya

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O-GlcNAc glycans in the mammalian extracellular environment

Tsukamoto, Y; Okajima, T

CARBOHYDRATE RESEARCH Vol. 549 page： 109378 2025.3

The Human Glycome Atlas project for cataloging all glycan-related omics data in human Reviewed Open Access

Aoki-Kinoshita, KF; Akune-Taylor, Y; Ando, H; Angata, K; Fujita, M; Furukawa, JI; Kaji, H; Kato, K; Kitajima, K; Kizuka, Y; Matsui, Y; Nakajima, K; Nishihara, S; Okajima, T; Sakamoto, K; Sato, C; Thaysen-Andersen, M; Togayachi, A; Yagi, H; Zappa, A; Kadomatsu, K

GLYCOBIOLOGY Vol. 34 ( 11 ) 2025.1

Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance

Hashimoto, N; Ito, S; Kudo, AY; Kawasaki, N; Hashimoto, N; Ito, S; Harazono, A; Tsuchida, A; Mouri, Y; Yamamoto, A; Okajima, T; Ohmi, Y; Furukawa, K; Kudo, Y; Kawasaki, N; Furukawa, K

ISCIENCE Vol. 27 ( 11 ) page： 111139 2024.11

The N-acetylglucosaminyltransferase Radical fringe contributes to defects in JAG1-dependent turnover and signaling of NOTCH3 CADASIL mutants Reviewed Open Access

Suzuki, S; Mashiko, T; Tsukamoto, Y; Oya, M; Kotani, Y; Okawara, S; Matsumoto, T; Mizue, Y; Takeuchi, H; Okajima, T; Itoh, M

JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 300 ( 10 ) page： 107787 2024.10

Characterization of galactosyltransferase and sialyltransferase genes mediating the elongation of the extracellular O-GlcNAc glycans Reviewed

Tsukamoto, Y; Tsukamoto, N; Saiki, W; Tashima, Y; Furukawa, JI; Kizuka, Y; Narimatsu, Y; Clausen, H; Takeuchi, H; Okajima, T

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 703 page： 149610 2024.4

Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1 Invited Reviewed

Kondo, Y; Li, YX; Okajima, T

MOLECULES Vol. 29 ( 5 ) 2024.3

Inhibitory machinery for the functional dystroglycan glycosylation Invited Reviewed

Kondo, Y; Okajima, T

JOURNAL OF BIOCHEMISTRY Vol. 173 ( 5 ) page： 333 - 335 2023.5

Evidence that only EWS among the FET proteins acquires a low partitioning property for the hyperosmotic stress response by O-GlcNAc glycosylation on its low-complexity domain Reviewed

Kakuo, M; Horii, T; Tonomura, N; Sato, R; Ogawa, M; Okajima, T; Kamemura, K

EXPERIMENTAL CELL RESEARCH Vol. 424 ( 1 ) page： 113504 2023.3

Secretory expression of mammalian NOTCH tandem epidermal growth factor-like repeats based on increased O-glycosylation Reviewed

Zhang, AL; Tsukamoto, Y; Takeuchi, H; Nishiwaki, K; Tashima, Y; Okajima, T

ANALYTICAL BIOCHEMISTRY Vol. 656 page： 114881 2022.11

Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1 Reviewed

Tsukamoto, Y; Ogawa, M; Yogi, K; Tashima, Y; Takeuchi, H; Okajima, T

GLYCOBIOLOGY Vol. 32 ( 7 ) page： 616 - 628 2022.6

Significant Roles of Notch O-Glycosylation in Cancer Invited Reviewed

Wang, WW; Okajima, T; Takeuchi, H

MOLECULES Vol. 27 ( 6 ) 2022.3

Unique effects of expression of asialo-series ganglioside GD1alpha in human cancer cell lines Reviewed

Robiul, B; Yesmin, F; Kondo, Y; Ohkawa, Y; Ohmi, Y; Zhang, P; Okajima, T; Furukawa, K; Furukawa, K

CANCER SCIENCE Vol. 113 page： 379 - 379 2022.2

Ganglioside GD2 enhances malignant properties of melanoma by co-operating with integrin. Reviewed

Farhana, Y; Bhuiyan, RH; Ohmi, Y; Horiuchi, M; Okajima, T; Yamamoto, S; Furukawa, K; Furukawa, K

CANCER SCIENCE Vol. 113 page： 1104 - 1104 2022.2

Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins Open Access

Yesmin, F; Bhuiyan, RH; Ohmi, Y; Yamamoto, S; Kaneko, K; Ohkawa, Y; Zhang, P; Hamamura, K; Cheung, NKV; Kotani, N; Honke, K; Okajima, T; Kambe, M; Tajima, O; Furukawa, K; Furukawa, K

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol. 23 ( 1 ) 2022.1

Eogt-catalyzed O-GlcNAcylation Invited Reviewed

Lo, PW; Okajima, T

TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY Vol. 34 ( 197 ) page： E1 - E6 2022.1

Other Classes of Eukaryotic Glycans Invited Reviewed International coauthorship

Haltiwanger RS, Wells L, Freeze HH, Jafar-Nejad H, Okajima T, Stanley P, Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Mohnen D, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH

2022

St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity Reviewed

Thane, P; Ohkawa, Y; Yamamoto, S; Momota, H; Kato, A; Kaneko, K; Natsume, A; Farhana, Y; Ohmi, Y; Okajima, T; Bhuiyan, RH; Wakabayashi, T; Furukawa, K; Furukawa, K

NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 83 ( 3 ) page： 535 - 549 2021.8

Majority of alpha2,6-sialylated glycans in the adult mouse brain exist in O-glycans: SALSA-MS analysis for knockout mice of alpha2,6-sialyltransferase genes Reviewed

Ohmi, Y; Nishikaze, T; Kitaura, Y; Ito, T; Yamamoto, S; Sugiyama, F; Matsuyama, M; Takahashi, Y; Takeda, A; Kawahara, T; Okajima, T; Furukawa, K; Furukawa, K

GLYCOBIOLOGY Vol. 31 ( 5 ) page： 557 - 570 2021.5

Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers Reviewed

Barua, R; Mizuno, K; Tashima, Y; Ogawa, M; Takeuchi, H; Taguchi, A; Okajima, T

MOLECULES Vol. 26 ( 4 ) 2021.2

Current Views on the Roles of O-Glycosylation in Controlling Notch-Ligand Interactions Invited Reviewed

Saiki, W; Ma, CY; Okajima, T; Takeuchi, H

BIOMOLECULES Vol. 11 ( 2 ) 2021.2

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Papers - OKAJIMA, Tetsuya