Faculty Profiles - SATO, Chihiro

Presentations -

Division display 161 - 175 of about 175 ／ All the affair displays >>

Identification of a new diSia-containing glycoprotein (adipoQ) in bovine and mouse sera

XVIth International Symposium on Glycoconjugates 2001.7.19

Glycosphingolipid enriched microdomain on gametic cells as functional domain for sperm-egg interaction coupled with signal transduction

Gordon Research Conference on Fertilization and Activation of the Development 1999.6.1

Frequent occurrence of oligosialyl units in vertebrate glycoproteins as evidenced by new chemical and immunochemical methods.

XIVth International Symposium on Glycoconjugates 1997.9.27

Egg receptor for sperm binds to gangliosides in the low density detergent-insoluble membrane (LD-DIM) domain of the sperm surface. Possible involvement of the LD-DIM in sperm-egg binding coupled with signal transduction during fertilization.

XVth International Symposium on Glycoconjugates 1999.8.1

Di- and oligosialic acids as novel carbohydrate epitopes in leukocytes

7th Conference on human leukocyte differentiation antigens 2000.6.1

Complex formation between polysialic acid and brain derived neurotrophic factor (BDNF).

Chihiro Sato, Yukihiro Kanato, Ken Kitajima

24th International Carbohydrate Symposium, 2008.7.27

Chain Length Diversity of Sialic Acids and Its Biological Significance International conference

SATO Chihiro

Trends in Glycoscience and Glycotechnology 2004.9 FCCA(Forum: Carbohydrates Coming of Age)

Language：English Presentation type：Oral presentation (general)

Sialic acids are commonly present as monosialyl residues at the non-reducing terminal end of glycoconjugates. In some cases, α2→8 linked di/oligosialic acid chains with DP 2 or 3 sialic acid residues are common structural units of gangliosides, and involved in various biological processes, such as cell adhesion, cell differentiation, signal transduction, and surface expression of stage specific antigen. In contrast, little attention has been paid to the occurrence and functions of such short sialyl di/oligomers on glycoproteins, while polysialic acid (DP≥8) in embryonic NCAM has been extensively studied as a regulator of cell adhesion in neurogenesis. As analytical methods to detect di/oligosialic acid structures have been improved, several glycoproteins containing di/oligo/polysialic acid chains have been identified. It is thus hypothesized that these di/oligosialic acid residues on glycoproteins may have similar important functions in common with those proposed for the gangliosides or may have new functions. Currently, several studies showing the importance of di/oligosialic acid-containing glycoproteins have emerged. In this review, recent advances in such studies of di/oligosialic acid residues on glycoproteins, including analytical methods, occurrence, biosynthetic pathways, and functions, are described.

Brain-derived neurotrophic factor binds to polysialic acid directly depending on degree of polymerization.

Yukihiro Kanato, Ken Kitajima, Chihiro Sato

SialoGlyco Conference 2008 2008.7

"Identification of adipo Q, an adipocyte-specific glycoprotein, as a new oligosialic acid-containing glycoprotein and a possible substrate for the a2,8-sialyltransferase III (ST8SiaIII)."

"International Symposium on Protein Traffic, Glycosylation, and Human Health" 2001.5.12

"Expression of a2,8-linked oligosialic acid-containing glycoproteins in mammalian cells, depending on development, cell differentiation, and overexpression of polysialyltransferase genes."

XIXth International Carbohydrate Symposium 1998.8.1

統合失調症に関わるポリシアル酸の構造と機能 -遺伝的要因と環境要因- Invited

JCGG シンポジウム 2023.11

New sialic acid binding region that regulates Siglec-7 and the frequent occurrence of the site among CD33-like Siglecs International coauthorship

Atsushi Yoshimura, Sayo Morishita, Mayu Miyashita, Hinano Komura, Masaya Hane, Wu Di, Ken Kitajima and Chihiro Sato

Glyco26 2023.8

脳にユニークな糖鎖、ポリシアル酸の構造と機能の解析 Invited

佐藤ちひろ

第96回日本生化学会大会 2023.10

Comparison of polysialic acid synthesized by ST8SIA2 and ST8SIA4

2023.9

Comparison of polysialic acid synthesized by ST8SIA2 and ST8SIA4 International conference

Chihiro SATO

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