Faculty Profiles - SATO, Chihiro

Presentations -

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ミクログリア細胞におけるポリシアル酸構造の存在.

矢部宇一郎、北島　健、霜田　靖、渡邊　和忠澤田　誠、佐藤ちひろ

第78回日本生化学会大会

An essential role of carbohydrate-enriched membrane microdomains (rafts) in gastrulation of medaka fish, Oryzias latipes. International conference

Gordon Research Conference on Glycobiology

Milk CD36 Hannah Research Institute International conference

Nagoya University Joint Workshop on Animal Biotechnology

糖タンパク質の多様なポリシアル酸修飾の意義を探る.

佐藤ちひろ

文科省特定領域研究糖鎖によるタンパク質と分子複合体の機能調節第三回夏期シンポジウム

Significance of membrane microdomains in the carbohydrate-dependent cell-cell interactions during early development of medaka fish.

The 2nd Japan-The Netherlands Glycobiology Symposium.

Biosynthesis and subcellular localiztion of deaminoneuraminic acid (KDN) in mammalian cells. International conference

The 18th International Symposium on Glycoconjugates.

Demonstration of N-glycan-binding activity of HSP70 and its importance in the chaperoning activity.

The 18th International Symposium on Glycoconjugates.

Development of a chemical method for detecting a unique sialic acid, cyclic neuraminic acid, in naturally-occurring sialyl glycoconjugates. International conference

Pacifichem

マウス乳糖タンパク質CD36上のポリシアル酸の乳腺発達段階における発現解析

矢部宇一郎、佐藤ちひろ、北島　健

日本農芸化学会2005年度大会

新規ポリシアル酸含有糖タンパク質flagellasialinの発見、構造および機能.

宮田真路, 佐藤ちひろ, 久美田紘信, 鳥山　優, Victor D. Vacquier, 北島　健

第25回日本糖質学会

ジ・オリゴシアル酸を含有するマウス血清糖タンパク質の同定

安川然太、佐藤ちひろ、北島　健

第3回糖鎖科学名古屋拠点　若手の力

メダカ初期胚における細胞膜ラフト形成の重要性とその役割.

足立朋子、佐藤ちひろ、北島　健

第3回糖鎖科学名古屋拠点　若手の力

Chain Length Diversity of Sialic Acids and Its Biological Significance

SATO Chihiro

Trends in Glycoscience and Glycotechnology

Event date： 2004.9

Language：English Presentation type：Oral presentation (general)

Sialic acids are commonly present as monosialyl residues at the non-reducing terminal end of glycoconjugates. In some cases, α2→8 linked di/oligosialic acid chains with DP 2 or 3 sialic acid residues are common structural units of gangliosides, and involved in various biological processes, such as cell adhesion, cell differentiation, signal transduction, and surface expression of stage specific antigen. In contrast, little attention has been paid to the occurrence and functions of such short sialyl di/oligomers on glycoproteins, while polysialic acid (DP≥8) in embryonic NCAM has been extensively studied as a regulator of cell adhesion in neurogenesis. As analytical methods to detect di/oligosialic acid structures have been improved, several glycoproteins containing di/oligo/polysialic acid chains have been identified. It is thus hypothesized that these di/oligosialic acid residues on glycoproteins may have similar important functions in common with those proposed for the gangliosides or may have new functions. Currently, several studies showing the importance of di/oligosialic acid-containing glycoproteins have emerged. In this review, recent advances in such studies of di/oligosialic acid residues on glycoproteins, including analytical methods, occurrence, biosynthetic pathways, and functions, are described.

DOI： 10.4052/tigg.16.331

Scopus

Preface for the Special Issue Entitled “New Waves in Sialobioscience”

Sato Chihiro

Trends in Glycoscience and Glycotechnology