Papers - HITOMI, Kiyotaka
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Identification of a highly reactive substrate peptudei for transglutaminase 6 and its use in detecting TGase activity in the skin epidermis Reviewed
Fukui M., Kuramoto K., Yamasaki R., Shimizu Y., Itoh M., Kawamoto T., Hitomi K.
Vol. 280 page： 1420-1429 2013.1
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Phage-displayed peptide liberary screening for preferred human substrate peptide sequences for transglutaminase 7 Reviewed
Kuramoto K., Yamasaki R., Shimizu Y., Tatsukawa H., Hitomi K
Archives Biochemistry and Biochemistry Vol. 537 ( 1 ) page： 138-143 2013
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Variations in both TG1 and TG2 isozyme-specific in situ activities and protein expressions during mouse embryonic development. Reviewed Open Access
Itoh M., Tatsukawa H., Lee E-S, Yamanishi K., Kojima S., and Hitomi K.
J. Histochem. Cytochem. Vol. 61 page： 793-801 2013.11
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Spatial arrangement of proteins using scCro-tag: application for an in situ enzymatic microbead assay Open Access
Kojima Takaaki, Hata Jumpei, Oka Hiroya, Hayashi Kenta, Hitomi Kiyotaka, Nakano Hideo
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY Vol. 82 ( 11 ) page： 1911-1921 2018.11
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Targeting transglutaminase 2 partially restores extracellular matrix structure but not alveolar architecture in experimental bronchopulmonary dysplasia Open Access
Mizikova Ivana, Pfeffer Tilman, Nardiello Claudio, Solaligue David E. Surate, Steenbock Heiko, Tatsukawa Hideki, Silva Diogo M., Vadasz Istvan, Herold Susanne, Pease Richard J., Iismaa Siiri E., Hitomi Kiyotaka, Seeger Werner, Brinckmann Juergen, Morty Rory E.
FEBS JOURNAL Vol. 285 ( 16 ) page： 3056-3076 2018.8
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Factor XIII-A transglutaminase acts as a switch between preadipocyte proliferation and differentiation. Reviewed Open Access
Myneni VD, Hitomi K., Kaartinen M.
Blood Vol. 124 page： 1344-1353 2014
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Distinct protein expression and activity of transglutaminases found in different epidermal tumors. Reviewed Open Access
Karashima T., Furumura M., Ishii N., Ohyama B., Saruta H., Natsuaki Y., Ohata C., Tsuruta D., Hitomi K., and Hashimoto T.
Exp. Dermatol. Vol. 23 page： 433-435 2014
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Detyrosinated Glu-tubulin is a substrate for cellular Factor XIIIA transglutaminase in differentiating osteoblast. Reviewed
Wang, S., Cui C., Hitomi K., Kaartinen M.
Amino Acids Vol. 46 page： 1513-1526 2014
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タンパク質架橋化酵素の高反応性基質の探索と活用 Invited
人見清隆
バイオサイエンスとバイオインダストリー Vol. 70 ( 6 ) page： 442-447 2012.11
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A distinct effect of transient and sustained upregulation of cellular factor XIII in the goldfish and optic nerve on optic nerve regeneration Reviewed
Sugitani, K., Ogai K., Hitomi, K., Nakamura-Yonehara K., Shintani T., Noda M., Kato S.
Neurochem. Int. Vol. 61 page： 423 2012.8
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Vena cava and aortic smooth muscle cells express transglutaminase 1 and 4 in addition to tranglutaminase 2 Reviewed Open Access
Johnson KB, Hitomi K, Itoh M, Bakker EN, , Watts SW et al.
American Journal of Physiology (circulation physiology) Vol. 302 ( 7 ) page： H1355-1366 2012.4
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Knocking-in the R142C mutation in transglutaminase 1 disrupts the stratum corneum barrier and postnatal survival of mice Reviewed
Nakagawa N., Yamamoto M., Imai Y., Sakaguchi Y., Takizawa T., Ohta N., Yagi N., Hatta I., Hitomi K., Takizawa T., Takeda J., Tsuda T., Matsuki M. Yamanishi K.
Journal of Dermatological Sciences Vol. 65 ( 3 ) page： 196-206 2012.3
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Bathing suit ichthyosis with summer exacerbation: a temperature-sensitive case Reviewed
Yamamoto M., Sakaguchi Y., Itoh M., Nakagawa N., Fukunaga A., Hitomi K., Yamanishi K.
Biritish Journal of Dermatology Vol. 166 ( 3 ) page： 671-693 2012.3
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Hornerin is a component of the epidermal cornified cell envelopes Reviewed
Henry J, Hsu C-Y, Haftek, M., Nachat R.,de Koning HD., Gardina-Galera I, Hitomi K. Balica, S., Jean-Decoster, C., Schmitt, A-M., Serre, G., SimonM
FASEB Journal ( 25 ) page： 1567-1576 2011.5
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Screening of substrate peptide sequences for tissue-type transglutaminase (TGase 2) Using T7 Phage cDNA Library. Reviewed Open Access
Sugimura Y., Yamashita H, Hitomi K.
Cytotechnology ( 63 ) page： 111-118 2011.3
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In situ detection of active transglutaminases for keratinocyte-type (TGase 1) and tissue-type (TGase 2) using fluorescence-labeled highly reactive substrate peptides. Reviewed
Itoh M., Kawamoto T., Tatsukawa H., Kojima S., Yamanishi, K., Hitomi, K.
Journal of Histochemistry and Cytochemistry ( 59 ) page： 180-187 2011.2
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Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles Reviewed
Yamane, A., Fukui, M., Sugimura Y., Itoh, M., Prez Alea P., Thomas V., El Alaoui S., Akiyama M., Hitomi K.
FEBS Journal Vol. 277 page： 3564–3574 2010.9
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The cystatin M/E-cathepsin L balance is essential for tissue homeostasis in epidermis, hair follicles, and cornea. Reviewed
Zeeuwen PM., van Vlijmen-Willems I., Cheng, T., Rodijk-Olthuis1, D., Hitomi K., Hara-Nishimura I., John S. Smyth, N., Reinheckel T., Hendriks WJ., and Schalkwijk J.
FASEB J. Vol. 24 page： 3744-3755 2010.5
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Transglutaminase1 Preferred Substrate Peptide K5 Is an Efficient Tool in Diagnosis of Lamellar Ichthyosis. Reviewed Open Access
Masashi Akiyama, Kaori Sakai, K., Teruki Yanagi, T., Fukushima, S., Ihn H., Hitomi K., and Hiroshi Shimizu, H.
Am. J. Pathol. Vol. 129 page： 2306-2309 2010.4
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*A specific colorimetric assay for measuring teranglutamianse 1 and factor XIII activities. Reviewed
Analytical Biochemistry Vol. 394 page： 281-283 2009.11