論文 - 早川 文彦
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The mTOR inhibitor, everolimus (RAD001), overcomes resistance to imatinib in quiescent Ph-positive acute lymphoblastic leukemia cells. 査読有り
Kuwatsuka Y, Minami M, Minami Y, Sugimoto K, Hayakawa F, Miyata Y, Abe A, Goff DJ, Kiyoi H, Naoe T.
Blood Cancer Journal 1 巻 ( e ) 頁： 17 2011年
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Missense mutations in PML-RARA critical for the lack of responsiveness to arsenic trioxide treatment. 査読有り
Goto E, Tomita A, Hayakawa F, Atsumi A, Kiyoi H, Naoe T.
Blood 118 巻 ( 6 ) 頁： 1600-9 2011年
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PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML. 査読有り
Kurahashi S, Hayakawa F, Miyata Y, Yasuda T, Minami Y, Tsuzuki S, Abe A, Naoe T.
Oncogene 30 巻 ( 14 ) 頁： 1822-30 2011年
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BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4. 査読有り
Suzuki M, Abe A, Imagama S, Nomura Y, Tanizaki R, Minami Y, Hayakawa F, Ito Y, Katsumi A, Yamamoto K, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. 84 巻 ( 3 ) 頁： 229-38 2010年
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Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy. 査読有り
Abe A, Minami Y, Hayakawa F, Kitamura K, Nomura Y, Murata M, Katsumi A, Kiyoi H, Jamieson CH, Wang JY, Naoe T.
Int J Hematol 88 巻 ( 5 ) 頁： 471-5 2008年
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Acetylation of PML is involved in histone deacetylase Inhibitor-mediated apoptosis. 査読有り
Hayakawa F, Abe A, Kitabayashi I, Pandolfi PP, Naoe T.
J Biol Chem. 283 巻 ( 36 ) 頁： 24420-5 2008年
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LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). 査読有り
Imagama S, Abe A, Suzuki M, Hayakawa F, Katsumi A, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. 79 巻 ( 1 ) 頁： 25-31 2007年
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Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing. 査読有り
Jonas BA, Varlakhanova N, Hayakawa F, Goodson M, Privalsky ML.
Mol Endocrinol 21 巻 ( 8 ) 頁： 1924-39 2007年
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Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. 査読有り
Okamoto M*, Hayakawa F*, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T
Leukemia 21 巻 ( 3 ) 頁： 403-10 2007年
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SFK-STAT pathway: an alternative and important way to malignancies. 査読有り
Hayakawa F, Naoe T
Ann N Y Acad Sci 1086 巻 ( 1 ) 頁： 213-22 2006年
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Establishment of a stroma-dependent human acute myelomonocytic leukemia cell line, NAMO-2, with FLT3 tandem duplication. 査読有り
Abe A, Kiyoi H, Ninomiya M, Yamazaki T, Murase T, Ozeki K, Suzuki M, Hayakawa F, Katsumi A, Emi N, Naoe T
Int J Hematol 84 巻 ( 4 ) 頁： 328 - 336 2006年
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Functional regulation of GATA-2 by acetylation. 査読有り
Hayakawa F, Towatari M, Ozawa Y, Tomita A, Privalsky ML, Saito H.
J Leukoc Biol 75 巻 ( 3 ) 頁： 529-40 2004年
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Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis. 査読有り
Hayakawa F, Privalsky ML
Cancer Cell 5 巻 ( 4 ) 頁： 389-401 2004年
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Life-threatening human parvovirus B19 infection transmitted by intravenous immune globulin. 査読有り
Hayakawa F, Imada K, Towatari M, Saito H.
Br J Haematol. 118 巻 ( 4 ) 頁： 1187-9 2002年
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Histone deacetylase 3 associates with and represses the transcription factor GATA-2. 査読有り
Ozawa Y, Towatari M, Tsuzuki S, Hayakawa F, Maeda T, Miyata Y, Tanimoto M, Saito H.
Blood 98 巻 ( 7 ) 頁： 2116-23 2001年
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c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300. 査読有り
Tomita A, Towatari M, Tsuzuki S, Hayakawa F, Kosugi H, Tamai K, Miyazaki T, Kinoshita T, Saito H.
Oncogene 19 巻 ( 3 ) 頁： 444-51 2000年
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Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. 査読有り
Hayakawa F, Towatari M, Kiyoi H, Tanimoto M, Kitamura T, Saito H, Naoe T
Oncogene 19 巻 ( 5 ) 頁： 624-31 2000年
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Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. 査読有り
Hayakawa F, Towatari M, Iida H, Wakao H, Kiyoi H, Naoe T, Saito H.
Brithish Journal of Haematology 101 巻 ( 3 ) 頁： 521-8 1998年