論文 - 早川 文彦
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Hayakawa, F; Mori, N; Imai, K; Yokoyama, Y; Katsuoka, Y; Saito, T; Murayama, T; Yamazaki, E; Sato, S; Atsuta, Y; Ishikawa, Y; Sakaida, E; Hatta, Y; Matsumura, I; Miyazaki, Y; Kiyoi, H
CANCER SCIENCE 116 巻 ( 2 ) 頁： 453 - 461 2024年11月
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Noura, M; Matsuo, H; Yasuda, T; Tsuzuki, S; Kiyoi, H; Hayakawa, F
ONCOGENE 43 巻 ( 6 ) 頁： 447 - 456 2024年2月
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Odaira, K; Yasuda, T; Okada, K; Shimooka, T; Kojima, Y; Noura, M; Tamura, S; Kurahashi, S; Iwamoto, E; Sanada, M; Matsumura, I; Miyazaki, Y; Kojima, T; Kiyoi, H; Tsuzuki, S; Hayakawa, F
CANCER SCIENCE 114 巻 ( 3 ) 頁： 781 - 792 2023年3月
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Yasuda, T; Sanada, M; Kawazu, M; Kojima, S; Tsuzuki, S; Ueno, H; Iwamoto, E; Iijima-Yamashita, Y; Yamada, T; Kanamori, T; Nishimura, R; Kuwatsuka, Y; Takada, S; Tanaka, M; Ota, S; Dobashi, N; Yamazaki, E; Hirose, A; Murayama, T; Sumi, M; Sato, S; Tange, N; Nakamura, Y; Katsuoka, Y; Sakaida, E; Kawamata, T; Iida, H; Shiraishi, Y; Nannya, Y; Ogawa, S; Taniwaki, M; Asou, N; Hatta, Y; Kiyoi, H; Matsumura, I; Horibe, K; Mano, H; Naoe, T; Miyazaki, Y; Hayakawa, F
BLOOD 139 巻 ( 12 ) 頁： 1850 - 1862 2022年3月
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Targeting MEF2D-fusion oncogenic transcriptional circuitries in B-cell precursor acute lymphoblastic leukemia 査読有り
Tsuzuki S, Yasuda T, Kojima S, Kawazu M, Akahane K, Inukai T, Imaizumi M, Morishita T, Miyamura K, Ueno T, Karnan S, Ota A, Hyodo T, Konishi H, Sanada M, Nagai H, Horibe K, Tomita A, Suzuki K, Muramatsu H, Takahashi Y, Miyazaki Y, Matsumura I, Kiyoi H, Hosokawa Y, Mano H, Hayakawa F
Blood Cancer Discovery 1 巻 ( 1 ) 頁： 82 - 95 2020年7月
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Tsuzuki, S; Yasuda, T; Kojima, S; Kawazu, M; Akahane, K; Inukai, T; Imaizumi, M; Morishita, T; Miyamura, K; Ueno, T; Karnan, S; Ota, A; Hyodo, T; Konishi, H; Sanada, M; Nagai, H; Horibe, K; Tomita, A; Suzuki, K; Muramatsu, H; Takahashi, Y; Miyazaki, Y; Matsumura, I; Kiyoi, H; Hosokawa, Y; Mano, H; Hayakawa, F
BLOOD CANCER DISCOVERY 1 巻 ( 1 ) 頁： 82 - 95 2020年7月
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Hirano, D; Hayakawa, F; Yasuda, T; Tange, N; Yamamoto, H; Kojima, Y; Morishita, T; Imoto, N; Tsuzuki, S; Mano, H; Naoe, T; Kiyoi, H
ONCOGENE 38 巻 ( 13 ) 頁： 2263 - 2274 2019年3月
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Okamoto, S; Suzuki, A; Tamura, S; Suzuki, N; Kanematsu, T; Suzuki, N; Kawaguchi, Y; Katsumi, A; Hayakawa, F; Kiyoi, H; Kojima, T; Matsushita, T
INTERNATIONAL JOURNAL OF HEMATOLOGY 121 巻 ( 1 ) 頁： 131 - 136 2025年1月
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Hatta, Y; Izutsu, K; Onizuka, M; Dobashi, N; Hayakawa, F; Yamazaki, E
INTERNATIONAL JOURNAL OF HEMATOLOGY 120 巻 ( 4 ) 頁： 394 - 413 2024年10月
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NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation 査読有り 国際誌
Noura, M; Tomita, S; Yasuda, T; Tsuzuki, S; Kiyoi, H; Hayakawa, F
CANCER MEDICINE 13 巻 ( 13 ) 頁： e7445 2024年7月
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<i>RGS1</i> and <i>CREB5</i> are direct and common transcriptional targets of ZNF384-fusion proteins 査読有り 国際誌
Yamada, C; Okada, K; Odaira, K; Tokoro, M; Iwamoto, E; Sanada, M; Noura, M; Okamoto, S; Yasuda, T; Tsuzuki, S; Kiyoi, H; Hayakawa, F
CANCER MEDICINE 13 巻 ( 14 ) 頁： e7471 2024年7月
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EBF1-JAK2 inhibits the PAX5 function through physical interaction with PAX5 and kinase activity 査読有り 国際誌
Kojima, Y; Kawashima, F; Yasuda, T; Odaira, K; Inagaki, Y; Yamada, C; Muraki, A; Noura, M; Okamoto, S; Tamura, S; Iwamoto, E; Sanada, M; Matsumura, I; Miyazaki, Y; Kojima, T; Kiyoi, H; Tsuzuki, S; Hayakawa, F
INTERNATIONAL JOURNAL OF HEMATOLOGY 118 巻 ( 1 ) 頁： 65 - 74 2023年7月
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Tsuzuki, S; Yasuda, T; Goto, H; Maeda, N; Akahane, K; Inukai, T; Yamamoto, H; Karnan, S; Ota, A; Hyodo, T; Konishi, H; Hosokawa, Y; Kiyoi, H; Hayakawa, F
HAEMATOLOGICA 108 巻 ( 2 ) 頁： 394 - 408 2023年2月
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Oncogenic lesions and molecular subtypes in adults with B-cell acute lymphoblastic leukemia 招待有り 査読有り 国際誌
Yasuda, T; Sanada, M; Tsuzuki, S; Hayakawa, F
CANCER SCIENCE 114 巻 ( 1 ) 頁： 8 - 15 2023年1月
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Okamoto, S; Tamura, S; Sanda, N; Odaira, K; Hayakawa, Y; Mukaide, M; Suzuki, A; Kanematsu, T; Hayakawa, F; Katsumi, A; Kiyoi, H; Kojima, T; Matsushita, T; Suzuki, N
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 20 巻 ( 8 ) 頁： 1784 - 1796 2022年8月
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Tamura, S; Mukaide, M; Katsuragi, Y; Fujii, W; Odaira, K; Suzuki, N; Tsukiji, N; Okamoto, S; Suzuki, A; Kanematsu, T; Katsumi, A; Takagi, A; Ikeda, K; Ueyama, J; Hirayama, M; Suzuki-Inoue, K; Matsushita, T; Kojima, T; Hayakawa, F
JOURNAL OF BIOLOGICAL CHEMISTRY 298 巻 ( 5 ) 頁： 101833 2022年5月
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Odaira, K; Kawashima, F; Tamura, S; Suzuki, N; Tokoro, M; Hayakawa, Y; Suzuki, A; Kanematsu, T; Okamoto, S; Takagi, A; Katsumi, A; Matsushita, T; Shima, M; Nogami, K; Kojima, T; Hayakawa, F
THROMBOSIS RESEARCH 213 巻 頁： 91 - 96 2022年5月
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Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases 査読有り 国際共著 国際誌
Dai, YT; Zhang, F; Fang, H; Li, JF; Lu, G; Jiang, L; Chen, B; Mao, DD; Liu, YF; Wang, J; Peng, LJ; Feng, C; Chen, HF; Mu, JX; Zhang, QL; Wang, H; Ariffin, H; Moy, TA; Wang, JH; Lou, YJ; Chen, SN; Wang, Q; Liu, H; Shan, Z; Matsumura, I; Miyazaki, Y; Yasuda, T; Dou, LP; Yan, XJ; Yan, JS; Yeoh, AEJ; Wu, DP; Kiyoi, H; Hayakawa, F; Jin, J; Wang, SY; Sun, XJ; Mi, JQ; Chen, Z; Huang, JY; Chen, SJ
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119 巻 ( 15 ) 頁： e2120787119 2022年4月
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Kako, S; Hayakawa, F; Miyamura, K; Tanaka, J; Imai, K; Kanda, J; Morishima, S; Uchida, N; Doki, N; Ikegame, K; Ozawa, Y; Takada, S; Usui, N; Ohtake, S; Kiyoi, H; Matsumura, I; Miyazaki, Y; Ichinohe, T; Fukuda, T; Atsuta, Y; Kanda, Y
TRANSPLANTATION AND CELLULAR THERAPY 28 巻 ( 3 ) 頁： 161.e1 - 161.e10 2022年3月
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Okada, K; Tamura, S; Suzuki, N; Odaira, K; Mukaide, M; Fujii, W; Katsuragi, Y; Suzuki, A; Kanematsu, T; Okamoto, S; Suzuki, N; Katsumi, A; Matsushita, T; Kojima, T; Hayakawa, F
THROMBOSIS RESEARCH 210 巻 頁： 26 - 32 2022年2月
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Sugiura, I; Doki, N; Hata, T; Cho, R; Ito, T; Suehiro, Y; Tanaka, M; Kako, S; Matsuda, M; Yokoyama, H; Ishikawa, Y; Taniguchi, Y; Hagihara, M; Ozawa, Y; Ueda, Y; Hirano, D; Sakura, T; Tsuji, M; Kamae, T; Fujita, H; Hiramoto, N; Onoda, M; Fujisawa, S; Hatta, Y; Dobashi, N; Nishiwaki, S; Atsuta, Y; Kobayashi, Y; Hayakawa, F; Ohtake, S; Naoe, T; Miyazaki, Y
BLOOD ADVANCES 6 巻 ( 2 ) 頁： 624 - 636 2022年1月
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Kako, S; Hayakawa, F; Imai, K; Tanaka, J; Mizuta, S; Nishiwaki, S; Kanamori, H; Mukae, J; Ozawa, Y; Kondo, T; Fukuda, T; Ichinohe, T; Ota, S; Tanaka, Y; Murayama, T; Kurahashi, S; Sakura, T; Usui, N; Ohtake, S; Kiyoi, H; Matsumura, I; Miyazaki, Y; Atsuta, Y
INTERNATIONAL JOURNAL OF HEMATOLOGY 114 巻 ( 5 ) 頁： 608 - 619 2021年11月
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Kunou, S; Shimada, K; Takai, M; Sakamoto, A; Aoki, T; Hikita, T; Kagaya, Y; Iwamoto, E; Sanada, M; Shimada, S; Hayakawa, F; Oneyama, C; Kiyoi, H
ONCOGENE 40 巻 ( 23 ) 頁： 3989 - 4003 2021年6月
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Essential role of a carboxyl-terminal α-helix motif in the secretion of coagulation factor XI 査読有り 国際誌
Hayakawa, Y; Tamura, S; Suzuki, N; Odaira, K; Tokoro, M; Kawashima, F; Hayakawa, F; Takagi, A; Katsumi, A; Suzuki, A; Okamoto, S; Kanematsu, T; Matsushita, T; Kojima, T
JOURNAL OF THROMBOSIS AND HAEMOSTASIS 19 巻 ( 4 ) 頁： 920 - 930 2021年4月
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Saito, T; Hatta, Y; Hayakawa, F; Takahashi, T; Hagihara, M; Iida, H; Minauchi, K; Yamazaki, E; Sugiura, I; Murayama, T; Sakura, T; Mori, N; Imai, K; Yahagi, Y; Atsuta, Y; Saito, AM; Hirakawa, A; Kiyoi, H; Matsumura, I; Miyazaki, Y
INTERNATIONAL JOURNAL OF HEMATOLOGY 113 巻 ( 3 ) 頁： 395 - 403 2021年3月
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Kagaya, Y; Shimada, K; Kunou, S; Hikita, T; Sakamoto, A; Hayakawa, F; Oneyama, C; Kiyoi, H
CANCER SCIENCE 112 巻 頁： 370 - 370 2021年2月
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[B cell acute lymphoblastic leukemia therapy: an up to date overview]. 招待有り 査読有り
Hayakawa F
[Rinsho ketsueki] The Japanese journal of clinical hematology 62 巻 ( 8 ) 頁： 1094 - 1101 2021年
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Kanayama, T; Imamura, T; Mayumi, A; Soma, E; Sakamoto, K; Hayakawa, F; Tanizawa, A; Kiyokawa, N; Hosoi, H
INTERNATIONAL JOURNAL OF HEMATOLOGY 112 巻 ( 5 ) 頁： 714 - 719 2020年11月
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Hatta, Y; Hayakawa, F; Yamazaki, E
INTERNATIONAL JOURNAL OF HEMATOLOGY 112 巻 ( 4 ) 頁： 439 - 458 2020年10月
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Tokoro, M; Tamura, S; Suzuki, N; Kakihara, M; Hattori, Y; Odaira, K; Suzuki, S; Takagi, A; Katsumi, A; Hayakawa, F; Okamoto, S; Suzuki, A; Kanematsu, T; Matsushita, T; Kojima, T
MOLECULAR GENETICS & GENOMIC MEDICINE 8 巻 ( 9 ) 頁： e1390 2020年9月
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Tange, N; Hayakawa, F; Yasuda, T; Odaira, K; Yamamoto, H; Hirano, D; Sakai, T; Terakura, S; Tsuzuki, S; Kiyoi, H
BIOMEDICINE & PHARMACOTHERAPY 128 巻 頁： 110330 2020年8月
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Yoshikawa, M; Takeichi, T; Taki, T; Hayakawa, F; Ishii, N; Hashimoto, T; Muro, Y; Akiyama, M
EUROPEAN JOURNAL OF DERMATOLOGY 30 巻 ( 4 ) 頁： 424 - 425 2020年7月
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Targeting MEF2D-fusion Oncogenic Transcriptional Circuitries in B-cell Precursor Acute Lymphoblastic Leukemia.
Tsuzuki S, Yasuda T, Kojima S, Kawazu M, Akahane K, Inukai T, Imaizumi M, Morishita T, Miyamura K, Ueno T, Karnan S, Ota A, Hyodo T, Konishi H, Sanada M, Nagai H, Horibe K, Tomita A, Suzuki K, Muramatsu H, Takahashi Y, Miyazaki Y, Matsumura I, Kiyoi H, Hosokawa Y, Mano H, Hayakawa F
Blood cancer discovery 1 巻 ( 1 ) 頁： 82 - 95 2020年7月
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High prevalence of MEF2D fusion in human B-cell precursor acute lymphoblastic leukemia cell lines. 査読有り
Akahane K, Yasuda T, Tsuzuki S, Hayakawa F, Kiyokawa N, Somazu S, Watanabe A, Kagami K, Abe M, Harama D, Goi K, Kawazu M, Kojima S, Imamura T, Goto H, Iwamoto S, Minegishi M, Abe M, Hojo H, Inaba T, Mano H, Sugita K, Inukai T
Hematological oncology 2020年6月
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Inoue, C; Sobue, S; Kawamoto, Y; Nishizawa, Y; Ichihara, M; Abe, A; Hayakawa, F; Suzuki, M; Nozawa, Y; Murate, T
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 525 巻 ( 4 ) 頁： 1074 - 1080 2020年5月
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Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes 査読有り
Inoue Chisato, Sobue Sayaka, Mizutani Naoki, Kawamoto Yoshiyuki, Nishizawa Yuji, Ichihara Masatoshi, Takeuchi Toshiyuki, Hayakawa Fumihiko, Suzuki Motoshi, Ito Tetsuro, Nozawa Yoshinori, Murate Takashi
NAGOYA JOURNAL OF MEDICAL SCIENCE 82 巻 ( 2 ) 頁： 261-280 2020年5月
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Ogawa, M; Suzuki, N; Takahashi, N; Tamura, S; Suzuki, A; Suzuki, S; Hattori, Y; Kakihara, M; Kanematsu, T; Kojima, T; Katsumi, A; Hayakawa, F; Kojima, T; Ishiguro, N; Kiyoi, H; Matsushita, T
THROMBOSIS RESEARCH 188 巻 頁： 103 - 105 2020年4月
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Dasatinib-Based Two-Step Induction Prior to Allogeneic Hematopoietic Cell Transplantation for Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of the JALSG Ph+ALL213 Study
Sugiura Isamu, Doki Noriko, Hata Tomoko, Cho Ryuko, Ito Toshiro, Suehiro Youko, Kanamori Heiwa, Kako Shinichi, Matsuda Mitsuhiro, Yokoyama Hisayuki, Taniguchi Yasuhiro, Hagihara Maki, Ozawa Yukiyasu, Fujisawa Shin, Dobashi Nobuaki, Hatta Yoshihiro, Asada Noboru, Ohashi Kazuteru, Onishi Yasushi, Shiro Koh, Nishiwaki Satoshi, Atsuta Yoshiko, Hayakawa Fumihiko, Ohtake Shigeki, Miyazaki Yasushi
BLOOD 134 巻 2019年11月
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Yamamoto, H; Hayakawa, F; Yasuda, T; Odaira, K; Minamikawa, Y; Tange, N; Hirano, D; Kojima, Y; Morishita, T; Tsuzuki, S; Naoe, T; Kiyoi, H
FEBS LETTERS 593 巻 ( 16 ) 頁： 2151 - 2161 2019年8月
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Odaira, K; Tamura, S; Suzuki, N; Kakihara, M; Hattori, Y; Tokoro, M; Suzuki, S; Takagi, A; Katsumi, A; Hayakawa, F; Okamoto, S; Suzuki, A; Kanematsu, T; Matsushita, T; Kojima, T
THROMBOSIS RESEARCH 179 巻 頁： 95 - 103 2019年7月
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Molecular basis of <i>SERPINC1</i> mutations in Japanese patients with antithrombin deficiency 査読有り 国際誌
Tamura, S; Hashimoto, E; Suzuki, N; Kakihara, M; Odaira, K; Hattori, Y; Tokoro, M; Suzuki, S; Takagi, A; Katsumi, A; Hayakawa, F; Suzuki, A; Okamoto, S; Kanematsu, T; Matsushita, T; Kojima, T
THROMBOSIS RESEARCH 178 巻 頁： 159 - 170 2019年6月
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[Peri-arteriolar megakaryopoietic microenvironment via reciprocal CLEC-2/PDPN axis in bone marrow]. 招待有り 査読有り
Tamura S, Suzuki-Inoue K, Ozaki Y, Hayakawa F, Kojima T
[Rinsho ketsueki] The Japanese journal of clinical hematology 60 巻 ( 7 ) 頁： 834-842 2019年
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Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases 査読有り 国際共著 国際誌
Li, JF; Dai, YT; Lilljebjörn, H; Shen, SH; Cui, BW; Bai, L; Liu, YF; Qian, MX; Kubota, Y; Kiyoi, H; Matsumura, I; Miyazaki, Y; Olsson, L; Tan, AM; Ariffin, H; Chen, J; Takita, J; Yasuda, T; Mano, H; Johansson, B; Yang, JJ; Yeoh, AEJ; Hayakawa, F; Chen, Z; Pui, CH; Fioretos, T; Chen, SJ; Huang, JY
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 115 巻 ( 50 ) 頁： E11711 - E11720 2018年12月
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Kanayama, T; Imamura, T; Sakamoto, K; Hayakawa, F; Tanizawa, A; Kiyokawa, N; Hosoi, H
BLOOD 132 巻 2018年11月
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Pyruvate secreted from patient-derived cancer-associated fibroblasts supports survival of primary lymphoma cells.
Sakamoto A, Kunou S, Shimada K, Tsunoda M, Aoki T, Iriyama C, Tomita A, Nakamura S, Hayakawa F, Kiyoi H
Cancer science 2018年11月
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Biology and management of primary effusion lymphoma.
Shimada K, Hayakawa F, Kiyoi H
Blood 132 巻 ( 18 ) 頁： 1879-1888 2018年11月
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Transcriptional activities of DUX4 fusions in B-cell acute lymphoblastic leukemia.
Tanaka Y, Kawazu M, Yasuda T, Tamura M, Hayakawa F, Kojima S, Ueno T, Kiyoi H, Naoe T, Mano H
Haematologica 103 巻 ( 11 ) 頁： e522-e526 2018年11月
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Hatta, Y; Mizuta, S; Matsuo, K; Ohtake, S; Iwanaga, M; Sugiura, I; Doki, N; Kanamori, H; Ueda, Y; Yoshida, C; Dobashi, N; Maeda, T; Yujiri, T; Monma, F; Ito, Y; Hayakawa, F; Takeuchi, J; Kiyoi, H; Miyazaki, Y; Naoe, T
ANNALS OF HEMATOLOGY 97 巻 ( 9 ) 頁： 1535 - 1545 2018年9月
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Inoue C, Sobue S, Aoyama Y, Mizutani N, Kawamoto Y, Nishizawa Y, Ichihara M, Abe A, Hayakawa F, Suzuki M, Nozawa Y, Murate T
Biochemistry and biophysics reports 15 巻 頁： 69 - 75 2018年9月
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Goto, T; Murata, M; Terakura, S; Nishida, T; Adachi, Y; Ushijima, Y; Shimada, K; Ishikawa, Y; Hayakawa, F; Nishio, N; Nishiwaki, S; Hirakawa, A; Kato, K; Takahashi, Y; Kiyoi, H
MEDICINE 97 巻 ( 17 ) 頁： e0449 2018年4月
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Sakura, T; Hayakawa, F; Sugiura, I; Murayama, T; Imai, K; Usui, N; Fujisawa, S; Yamauchi, T; Yujiri, T; Kakihana, K; Ito, Y; Kanamori, H; Ueda, Y; Miyata, Y; Kurokawa, M; Asou, N; Ohnishi, K; Ohtake, S; Kobayashi, Y; Matsuo, K; Kiyoi, H; Miyazaki, Y; Naoe, T
LEUKEMIA 32 巻 ( 3 ) 頁： 626 - 632 2018年3月
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High Incidence of Extensive Chronic Gvhd in Patients with the <i>REG3A</i> Rs7588571 Non-GG Genotype 査読有り 国際誌
Murata, M; Koyama, D; Hanajiri, R; Okuno, S; Kamoshita, S; Julamanee, J; Takagi, E; Hirano, D; Miyao, K; Sakemura, R; Goto, T; Hayakawa, F; Seto, A; Ozawa, Y; Miyamura, K; Terakura, S; Nishida, T; Kiyoi, H
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 24 巻 ( 3 ) 頁： S192 - S193 2018年3月
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Yamaura, T; Nakatani, T; Uda, K; Ogura, H; Shin, W; Kurokawa, N; Saito, K; Fujikawa, N; Date, T; Takasaki, M; Terada, D; Hirai, A; Akashi, A; Chen, F; Adachi, Y; Ishikawa, Y; Hayakawa, F; Hagiwara, S; Naoe, T; Kiyoi, H
BLOOD 131 巻 ( 4 ) 頁： 426 - 438 2018年1月
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[Adult acute lymphoblastic leukemia: update on pathophysiology and management].
Hayakawa F
[Rinsho ketsueki] The Japanese journal of clinical hematology 59 巻 ( 5 ) 頁： 497 - 503 2018年
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The transcriptional landscape of B-cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases 査読有り
Jian-Feng Li, Yu-Ting Dai, Henrik Lilljebjörn, Shu-Hong Shen, Bo-Wen Cui, Ling Bai, Yuan-Fang Liu, Mao-Xiang Qian, Yasuo Kubota, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki, Linda Olsson, Ah Moy Tan, Hany Ariffin, Jing Chen, Junko Takita, Takahiko Yasuda, Hiroyuki Mano, Bertil Johansson, Jun J. Yang, Allen Eng-Juh Yeoh, Fumihiko Hayakawa, Zhu Chen, Ching-Hon Pui, Thoas Fioretos, Sai-Juan Chen, Jin-Yan Huang
Proceedings of the National Academy of Sciences of the United Stats of America in press 巻 ( in press ) 頁： in press 2018年
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Koyama, D; Murata, M; Hanajiri, R; Okuno, S; Kamoshita, S; Julamanee, J; Takagi, E; Hirano, D; Miyao, K; Sakemura, R; Goto, T; Hayakawa, F; Seto, A; Ozawa, Y; Miyamura, K; Terakura, S; Nishida, T; Kiyoi, H
PLOS ONE 12 巻 ( 9 ) 頁： e0185213 2017年9月
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Kojima, Y; Hayakawa, F; Morishita, T; Sugimoto, K; Minamikawa, Y; Iwase, M; Yamamoto, H; Hirano, D; Imoto, N; Shimada, K; Okada, S; Kiyoi, H
PHARMACOLOGICAL RESEARCH 120 巻 頁： 242 - 251 2017年6月
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Aoki, T; Shimada, K; Sakamoto, A; Sugimoto, K; Morishita, T; Kojima, Y; Shimada, S; Kato, S; Iriyama, C; Kuno, S; Harada, Y; Tomita, A; Hayakawa, F; Kiyoi, H
ONCOTARGET 8 巻 ( 8 ) 頁： 13085 - 13098 2017年2月
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[Acute lymphoblastic leukemia of adolescents and young adults: from the viewpoint of physicians].
Yasuda T, Hayakawa F
[Rinsho ketsueki] The Japanese journal of clinical hematology 58 巻 ( 8 ) 頁： 1031 - 1037 2017年
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[Malignant lymphoma with cardiac involvement].
Terakura S, Onji M, Iriyama C, Goto T, Ushijima Y, Shimada K, Ishikawa Y, Nishida T, Hayakawa F, Murata M, Kiyoi H
[Rinsho ketsueki] The Japanese journal of clinical hematology 58 巻 ( 3 ) 頁： 239 - 242 2017年
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The photosensitizer verteporfin has light-independent anti-leukemic activity for Ph-positive acute lymphoblastic leukemia and synergistically works with dasatinib. 査読有り
Morishita T, Hayakawa F, Sugimoto K, Iwase M, Yamamoto H, Hirano D, Kojima Y, Imoto N, Naoe T, Kiyoi H.
Oncotarget. 7 巻 頁： 56241 2016年7月
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Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions. 査読有り
Sugimoto K, Miyata Y, Nakayama T, Saito S, Suzuki R, Hayakawa F, Nishiwaki S, Mizuno H, Takeshita K, Kato H, Ueda R, Takami A, Naoe T.
Scientific Reports 6 巻 頁： 30779 2016年7月
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PAX5 tyrosine phosphorylation by SYK co-operatively functions with its serine phosphorylation to cancel the PAX5-dependent repression of BLIMP1: A mechanism for antigen-triggered plasma cell differentiation. 査読有り
Inagaki Y, Hayakawa F, Hirano D, Kojima Y, Morishita T, Yasuda T, Naoe T, Kiyoi H.
Biochem Biophys Res Commun. 475 巻 ( 2 ) 頁： 176 2016年5月
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SPIB is a novel prognostic factor in diffuse large B-cell lymphoma that mediates apoptosis via the PI3K-AKT pathway. 査読有り
Takagi Y, Shimada K, Shimada S, Sakamoto A, Naoe T, Nakamura S, Hayakawa F, Tomita A, Kiyoi H.
Cancer Science 107 巻 ( 9 ) 頁： 1270 2016年4月
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Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults. 査読有り
Yasuda T, Tsuzuki S, Kawazu M, Hayakawa F, Kojima S, Ueno T, Imoto N, Kohsaka S, Kunita A, Doi K, Sakura T, Yujiri T, Kondo E, Fujimaki K, Ueda Y, Aoyama Y, Ohtake S, Takita J, Sai E, Taniwaki M, Kurokawa M, Morishita S, Fukayama M, Kiyoi H, Miyazaki Y, Naoe T, Mano H.
Nature Genetics 48 巻 ( 5 ) 頁： 569 2016年3月
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Development and analysis of patient-derived xenograft mouse models in intravascular large B-cell lymphoma. 査読有り
Shimada K, Shimada S, Sugimoto K, Nakatochi M, Suguro M, Hirakawa A, Hocking TD, Takeuchi I, Tokunaga T, Takagi Y, Sakamoto A, Aoki T, Naoe T, Nakamura S, Hayakawa F, Seto M, Tomita A, Kiyoi H.
Leukemia 30 巻 ( 7 ) 頁： 1568 2016年2月
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Wnt signaling is associated with cell survival in the interaction between acute myeloid leukemia cells and stromal cells. 査読有り
Niwa Y, Minami Y, Abe A, Hayakawa F, Yamada K, Naoe T.
Leukemia & Lymphoma 57 巻 ( 9 ) 頁： 2192 2016年1月
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B Cell Linker Protein (BLNK) Is a Selective Target of Repression by PAX5-PML Protein in the Differentiation Block That Leads to the Development of Acute Lymphoblastic Leukemia. 査読有り
Imoto N, Hayakawa F, Kurahashi S, Morishita T, Kojima Y, Yasuda T, Sugimoto K, Tsuzuki S, Naoe T, Kiyoi H.
Journal of Biological Chemistry 291 巻 ( 9 ) 頁： 4723 2016年1月
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Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells. 査読有り 国際共著
Fukushima N, Minami Y, Kakiuchi S, et al.
Cancer Science 107 巻 頁： 1422 2016年
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【臨床血液学-最新情報と今後の展望2016(リンパ系疾患)-】 成人急性リンパ性白血病 招待有り 査読有り
早川文彦
臨床血液 57 巻 頁： 230 2016年
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Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions. 査読有り
Sugimoto K, Miyata Y, Nakayama T, et al.
Scientific reports 6 巻 頁： 30799 2016年
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Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells 査読有り
Keiki Sugimoto, Fumihiko Hayakawa, Satoko Shimada, Takanobu Morishita, Kazuyuki Shimada, Tomoya Katakai, Akihiro Tomita, Hitoshi Kiyoi, Tomoki Naoe
Scientific reports 5 巻 頁： 13054 2015年8月
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Phase I study of OPB-51602, an oral inhibitor of signal transducer and activator of transcription 3, in patients with relapsed/refractory hematological malignancies. 査読有り
Ogura M, Uchida T, Terui Y, Hayakawa F, Kobayashi Y, Taniwaki M, Takamatsu Y, Naoe T, Tobinai K, Munakata W, Yamauchi T, Kageyama A, Yuasa M, Motoyama M, Tsunoda T, Hatake K.
Cancer Science 106 巻 ( 7 ) 頁： 896-901 2015年5月
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Anti-cancer fatty-acid derivative induces autophagic cell death through modulation of PKM isoform expression profile mediated by bcr-abl in chronic myeloid leukemia. 査読有り
Shinohara H, Taniguchi K, Kumazaki M, Yamada N, Ito Y, Otsuki Y, Uno B, Hayakawa F, Minami Y, Naoe T, Akao Y.
Cancer Letter 360 巻 ( 1 ) 頁： 28-38 2015年1月
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Adolescent and young adult世代の急性リンパ性白血病 招待有り 査読有り
早川文彦
臨床血液 56 巻 頁： 2032 2015年
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Development of acute pure red cell aplasia after deferasirox administration in two cases of myelodysplastic syndrome. 査読有り
Hayakawa F, Tomita A, Naoe T.
Rinsho Ketsueki 55 巻 ( 4 ) 頁： 445-9 2014年
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Markedly improved outcomes and acceptable toxicity in adolescents and young adults with acute lymphoblastic leukemia following treatment with a pediatric protocol: a phase II study by the Japan Adult Leukemia Study Group. 査読有り
Hayakawa F, Sakura T, Yujiri T, Kondo E, Fujimaki K, Sasaki O, Miyatake J, Handa H, Ueda Y, Aoyama Y, Takada S, Tanaka Y, Usui N, Miyawaki S, Suenobu S, Horibe K, Kiyoi H, Ohnishi K, Miyazaki Y, Ohtake S, Kobayashi Y, Matsuo K, Naoe T
Blood Cancer Journal 4 巻 ( e ) 頁： 252 2014年
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GATA2 zinc finger 2 mutation found in acute myeloid leukemia impairs myeloid differentiation. 査読有り
Niimi K, Kiyoi H, Ishikawa Y, Hayakawa F, Kurahashi S, Kihara R, Tomita A, Naoe T.
Leuk Res Rep 2 巻 ( 1 ) 頁： 21-5 2013年
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A novel STAT inhibitor, OPB-31121, has a significant antitumor effect on leukemia with STAT-addictive oncokinases. 査読有り
Hayakawa F, Sugimoto K, Harada Y, Hashimoto N, Ohi N, Kurahashi S, Naoe T.
Blood Cancer Journal 3 巻 ( e ) 頁： 166 2013年
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B cell receptor-ERK1/2 signal cancels PAX5-dependent repression of BLIMP1 through PAX5 phosphorylation: a mechanism of antigen-triggering plasma cell differentiation. 査読有り
Yasuda T,Hayakawa F,Kurahashi S, Sugimoto K, Miyami Y, Tomita A, Naoe
Journal of Immunology 188 巻 ( 12 ) 頁： 6127-34 2012年
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The mTOR inhibitor, everolimus (RAD001), overcomes resistance to imatinib in quiescent Ph-positive acute lymphoblastic leukemia cells. 査読有り
Kuwatsuka Y, Minami M, Minami Y, Sugimoto K, Hayakawa F, Miyata Y, Abe A, Goff DJ, Kiyoi H, Naoe T.
Blood Cancer Journal 1 巻 ( e ) 頁： 17 2011年
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Missense mutations in PML-RARA critical for the lack of responsiveness to arsenic trioxide treatment. 査読有り
Goto E, Tomita A, Hayakawa F, Atsumi A, Kiyoi H, Naoe T.
Blood 118 巻 ( 6 ) 頁： 1600-9 2011年
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PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML. 査読有り
Kurahashi S, Hayakawa F, Miyata Y, Yasuda T, Minami Y, Tsuzuki S, Abe A, Naoe T.
Oncogene 30 巻 ( 14 ) 頁： 1822-30 2011年
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BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4. 査読有り
Suzuki M, Abe A, Imagama S, Nomura Y, Tanizaki R, Minami Y, Hayakawa F, Ito Y, Katsumi A, Yamamoto K, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. 84 巻 ( 3 ) 頁： 229-38 2010年
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Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy. 査読有り
Abe A, Minami Y, Hayakawa F, Kitamura K, Nomura Y, Murata M, Katsumi A, Kiyoi H, Jamieson CH, Wang JY, Naoe T.
Int J Hematol 88 巻 ( 5 ) 頁： 471-5 2008年
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Acetylation of PML is involved in histone deacetylase Inhibitor-mediated apoptosis. 査読有り
Hayakawa F, Abe A, Kitabayashi I, Pandolfi PP, Naoe T.
J Biol Chem. 283 巻 ( 36 ) 頁： 24420-5 2008年
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LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). 査読有り
Imagama S, Abe A, Suzuki M, Hayakawa F, Katsumi A, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. 79 巻 ( 1 ) 頁： 25-31 2007年
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Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing. 査読有り
Jonas BA, Varlakhanova N, Hayakawa F, Goodson M, Privalsky ML.
Mol Endocrinol 21 巻 ( 8 ) 頁： 1924-39 2007年
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Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. 査読有り
Okamoto M*, Hayakawa F*, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T
Leukemia 21 巻 ( 3 ) 頁： 403-10 2007年
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SFK-STAT pathway: an alternative and important way to malignancies. 査読有り
Hayakawa F, Naoe T
Ann N Y Acad Sci 1086 巻 ( 1 ) 頁： 213-22 2006年
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Establishment of a stroma-dependent human acute myelomonocytic leukemia cell line, NAMO-2, with FLT3 tandem duplication. 査読有り
Abe A, Kiyoi H, Ninomiya M, Yamazaki T, Murase T, Ozeki K, Suzuki M, Hayakawa F, Katsumi A, Emi N, Naoe T
Int J Hematol 84 巻 ( 4 ) 頁： 328 - 336 2006年
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Functional regulation of GATA-2 by acetylation. 査読有り
Hayakawa F, Towatari M, Ozawa Y, Tomita A, Privalsky ML, Saito H.
J Leukoc Biol 75 巻 ( 3 ) 頁： 529-40 2004年
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Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis. 査読有り
Hayakawa F, Privalsky ML
Cancer Cell 5 巻 ( 4 ) 頁： 389-401 2004年
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Life-threatening human parvovirus B19 infection transmitted by intravenous immune globulin. 査読有り
Hayakawa F, Imada K, Towatari M, Saito H.
Br J Haematol. 118 巻 ( 4 ) 頁： 1187-9 2002年
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Histone deacetylase 3 associates with and represses the transcription factor GATA-2. 査読有り
Ozawa Y, Towatari M, Tsuzuki S, Hayakawa F, Maeda T, Miyata Y, Tanimoto M, Saito H.
Blood 98 巻 ( 7 ) 頁： 2116-23 2001年
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c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300. 査読有り
Tomita A, Towatari M, Tsuzuki S, Hayakawa F, Kosugi H, Tamai K, Miyazaki T, Kinoshita T, Saito H.
Oncogene 19 巻 ( 3 ) 頁： 444-51 2000年
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Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. 査読有り
Hayakawa F, Towatari M, Kiyoi H, Tanimoto M, Kitamura T, Saito H, Naoe T
Oncogene 19 巻 ( 5 ) 頁： 624-31 2000年
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Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. 査読有り
Hayakawa F, Towatari M, Iida H, Wakao H, Kiyoi H, Naoe T, Saito H.
Brithish Journal of Haematology 101 巻 ( 3 ) 頁： 521-8 1998年