Papers - HAYAKAWA, Fumihiko
-
Missense mutations in PML-RARA critical for the lack of responsiveness to arsenic trioxide treatment. Reviewed
Goto E, Tomita A, Hayakawa F, Atsumi A, Kiyoi H, Naoe T.
Blood Vol. 118 ( 6 ) page： 1600-9 2011
-
PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML. Reviewed
Kurahashi S, Hayakawa F, Miyata Y, Yasuda T, Minami Y, Tsuzuki S, Abe A, Naoe T.
Oncogene Vol. 30 ( 14 ) page： 1822-30 2011
-
The mTOR inhibitor, everolimus (RAD001), overcomes resistance to imatinib in quiescent Ph-positive acute lymphoblastic leukemia cells. Reviewed
Kuwatsuka Y, Minami M, Minami Y, Sugimoto K, Hayakawa F, Miyata Y, Abe A, Goff DJ, Kiyoi H, Naoe T.
Blood Cancer Journal Vol. 1 ( e ) page： 17 2011
-
BCR-ABL-independent and RAS / MAPK pathway-dependent form of imatinib resistance in Ph-positive acute lymphoblastic leukemia cell line with activation of EphB4. Reviewed
Suzuki M, Abe A, Imagama S, Nomura Y, Tanizaki R, Minami Y, Hayakawa F, Ito Y, Katsumi A, Yamamoto K, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. Vol. 84 ( 3 ) page： 229-38 2010
-
Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy. Reviewed
Abe A, Minami Y, Hayakawa F, Kitamura K, Nomura Y, Murata M, Katsumi A, Kiyoi H, Jamieson CH, Wang JY, Naoe T.
Int J Hematol Vol. 88 ( 5 ) page： 471-5 2008
-
Acetylation of PML is involved in histone deacetylase Inhibitor-mediated apoptosis. Reviewed
Hayakawa F, Abe A, Kitabayashi I, Pandolfi PP, Naoe T.
J Biol Chem. Vol. 283 ( 36 ) page： 24420-5 2008
-
LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). Reviewed
Imagama S, Abe A, Suzuki M, Hayakawa F, Katsumi A, Emi N, Kiyoi H, Naoe T.
Eur J Haematol. Vol. 79 ( 1 ) page： 25-31 2007
-
Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing. Reviewed
Jonas BA, Varlakhanova N, Hayakawa F, Goodson M, Privalsky ML.
Mol Endocrinol Vol. 21 ( 8 ) page： 1924-39 2007
-
Lyn is an important component of the signal transduction pathway specific to FLT3/ITD and can be a therapeutic target in the treatment of AML with FLT3/ITD. Reviewed
Okamoto M*, Hayakawa F*, Miyata Y, Watamoto K, Emi N, Abe A, Kiyoi H, Towatari M, Naoe T
Leukemia Vol. 21 ( 3 ) page： 403-10 2007
-
SFK-STAT pathway: an alternative and important way to malignancies. Reviewed
Hayakawa F, Naoe T
Ann N Y Acad Sci Vol. 1086 ( 1 ) page： 213-22 2006
-
Establishment of a stroma-dependent human acute myelomonocytic leukemia cell line, NAMO-2, with FLT3 tandem duplication. Reviewed
Abe A, Kiyoi H, Ninomiya M, Yamazaki T, Murase T, Ozeki K, Suzuki M, Hayakawa F, Katsumi A, Emi N, Naoe T
Int J Hematol Vol. 84 ( 4 ) page： 328 - 336 2006
-
Functional regulation of GATA-2 by acetylation. Reviewed
Hayakawa F, Towatari M, Ozawa Y, Tomita A, Privalsky ML, Saito H.
J Leukoc Biol Vol. 75 ( 3 ) page： 529-40 2004
-
Phosphorylation of PML by mitogen-activated protein kinases plays a key role in arsenic trioxide-mediated apoptosis. Reviewed
Hayakawa F, Privalsky ML
Cancer Cell Vol. 5 ( 4 ) page： 389-401 2004
-
Life-threatening human parvovirus B19 infection transmitted by intravenous immune globulin. Reviewed
Hayakawa F, Imada K, Towatari M, Saito H.
Br J Haematol. Vol. 118 ( 4 ) page： 1187-9 2002
-
Histone deacetylase 3 associates with and represses the transcription factor GATA-2. Reviewed
Ozawa Y, Towatari M, Tsuzuki S, Hayakawa F, Maeda T, Miyata Y, Tanimoto M, Saito H.
Blood Vol. 98 ( 7 ) page： 2116-23 2001
-
c-Myb acetylation at the carboxyl-terminal conserved domain by transcriptional co-activator p300. Reviewed
Tomita A, Towatari M, Tsuzuki S, Hayakawa F, Kosugi H, Tamai K, Miyazaki T, Kinoshita T, Saito H.
Oncogene Vol. 19 ( 3 ) page： 444-51 2000
-
Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines. Reviewed
Hayakawa F, Towatari M, Kiyoi H, Tanimoto M, Kitamura T, Saito H, Naoe T
Oncogene Vol. 19 ( 5 ) page： 624-31 2000
-
Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. Reviewed
Hayakawa F, Towatari M, Iida H, Wakao H, Kiyoi H, Naoe T, Saito H.
Brithish Journal of Haematology Vol. 101 ( 3 ) page： 521-8 1998