Papers - AKATSUKA, Shinya
-
Stage-specific roles of fibulin-5 during oxidative stress-induced renal carcinogenesis in rats Reviewed
Ohara H, Akatsuka S, Nagai H, Liu YT, Jiang L, Okazaki Y, Yamashita Y, Nakamura T, Toyokuni S.
Free Radic Res Vol. 45 ( 2 ) page： 211-220 2011.2
-
Genome-scale approaches to investigate oxidative DNA damage Reviewed
Akatsuka S, Toyokuni S.
J Clin Biochem Nutr Vol. 47 ( 2 ) page： 91-97 2010.9
-
Suppression of SLC11A2 expression is essential to maintain duodenal integrity during dietary iron overload Reviewed
Shirase T, Mori K, Okazaki Y, Itoh K, Yamamoto M, Tabuchi M, Kishi F, Jiang L, Akatsuka S, Nakao K, Toyokuni S.
Am J Pathol Vol. 177 ( 2 ) page： 677-685 2010.8
-
*A quantitative trait locus responsible for inducing B‐cell lymphoblastic lymphoma is a hotspot for microsatellite instability Reviewed
Kaszynski RH, Akatsuka S, Hiratsuka T, Jin G, Ozeki M, Okuno T, Nakamura T, Manabe T, Takakuwa T, Hiai H, Toyokuni S, Tamaki K, Tsuruyama T.
Cancer Sci Vol. 101 ( 3 ) page： 800-805 2010.3
-
Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. Reviewed
Hu Q, Akatsuka S, Yamashita Y, Ohara H, Nagai H, Okazaki Y, Takahashi T, Toyokuni S.
Lab Invest Vol. 90 ( 3 ) page： 360-373 2010.3
-
Genome-wide analysis identifies a tumor suppressor role for aminoacylase 1 in iron-induced rat renal cell carcinoma. Reviewed
Zhong Y, Onuki J, Yamasaki T, Ogawa O, Akatsuka S, Toyokuni S.
Carcinogenesis Vol. 30 ( 1 ) page： 158-164 2009.1
-
Characteristics and modifying factors of asbestos-induced oxidative DNA damage Reviewed
Jiang L, Nagai H, Ohara H, Hara S, Tachibana M, Hirano S, Shinohara Y, Kohyama N, Akatsuka S, Toyokuni S
Cancer Sci Vol. 99 ( 11 ) page： 2142-2151 2008.11
-
*Chronic oxidative stress causes amplification and overexpression of ptprz1 protein tyrosine phosphatase to activate beta-catenin pathway Reviewed
Liu YT, Shang D, Akatsuka S, Ohara H, Dutta KK, Mizushima K, Naito Y, Yoshikawa T, Izumiya M, Abe K, Nakagama H, Noguchi N, Toyokuni S
Am J Pathol Vol. 171 ( 6 ) page： 1978-1988 2007.12
-
Pathological investigation of oxidative stress in the post-genomic era Reviewed
Toyokuni S, Akatsuka S.
Pathol Int Vol. 57 ( 8 ) page： 461-473 2007.12
-
Association of microRNA-34a overexpression with proliferation is cell type-dependent Reviewed
Dutta KK, Zhong Y, Liu YT, Yamada T, Akatsuka S, Hu Q, Yoshihara M, Ohara H, Takehashi M, Shinohara T, Masutani H, Onuki J, Toyokuni S
Cancer Sci Vol. 98 ( 12 ) page： 1845-1852 2007.12
-
Novel screening method for ultraviolet protection: combination of a human skin-equivalent model and 8-hydroxy-2'-deoxyguanosine Reviewed
Toyokuni S, Yasui H, Date A, Hakozaki T, Akatsuka S, Kohda H, Yoshii T, Sakurai H
Pathol Int Vol. 56 ( 12 ) page： 760-762 2006.12
-
Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment Reviewed
Jiang L, Zhong Y, Akatsuka S, Liu Y-T, Dutta KK, Lee W-H, Onuki J, Masymura K, Nohmi T, Toyokuni S
Cancer Sci Vol. 97 ( 11 ) page： 1159-1167 2006.11
-
*Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis. Reviewed
Akatsuka S, Aung TT, Dutta KK, Jiang L, Lee W-H, Liu Y-T, Onuki J, Shirase T, Yamasaki K, Ochi H, Naito Y, Yoshikawa T, Kasai H, Tominaga Y, Sakumi K, Nakabeppu Y, Kawai Y, Uchida K, Yamasaki A, Tsuruyama T, Yamada Y, Toyokuni S
Am J Pathol Vol. 169 ( 4 ) page： 1328-1342 2006.10
-
Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage Reviewed
Lee W-H, Akatsuka S, Shirase T, Dutta KK, Jiang L, Liu Y-T, Onuki J, Yamada Y, Okawa K, Wada Y, Watanabe A, Kohro T, Noguchi N, Toyokuni S
Arch Biochem Biophys Vol. 453 ( 2 ) page： 168-178 2006.9
-
What has been learned from the studies of oxidative stress-induced carcinogenesis: proposal of the concept of oxygenomics Reviewed
Toyokuni S, Akatsuka S.
J Clin Biochem Nutr Vol. 39 ( 1 ) page： 3-10 2006.7
-
Susceptibility of actin to modification by 4-hydroxy-2-nonenal Reviewed
Ozeki M, Miyagawa-Hayashino A, Akatsuka S, Shirase T, Lee W-H, Uchida K, Toyokuni S
J Chromatogr B Analyt Technol Biomed Life Sci Vol. 827 ( 1 ) page： 119-126 2005.11
-
Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis Reviewed
Dutta KK, Nishinaka Y, Masutani H, Akatsuka S, Aung TT, Shirase T, Lee W-H, Yamada Y, Hiai H, Yodoi J, Toyokuni S
Lab Invest Vol. 85 ( 6 ) page： 798-807 2005.6
-
Redox regulation of annexin 2 and its implications for oxidative stress-induced renal carcinogenesis and metastasis Reviewed
Tanaka T, Akatsuka S, Ozeki M, Shirase T, Hiai H, Toyokuni S
Oncogene Vol. 23 ( 22 ) page： 3980-3989 2004.5
-
Detection of glyceraldehyde 3-phosphate dehydrogenase messenger RNA using a peptide nucleic acid probe in paraffin-embedded archival specimens Reviewed
Hiroyasu M, Akatsuka S, Shirase T, Toda Y, Hiai H, Toyokuni S
Pathol Int Vol. 54 ( 4 ) page： 251-255 2004.4
-
Effects of phenolic contents of Mauritian endemic plant extracts on promoter activities of antioxidant enzymes Reviewed
Toyokuni S, Tanaka T, Kawaguchi W, Fang NRL, Ozeki M, Akatsuka S, Hiai H, Aruoma OI, Bahorun T
Free Radic Res Vol. 37 ( 11 ) page： 1215-1224 2003.11