研究者詳細 - 大平　英樹

論文 - 大平　英樹

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認知課題遂行による不快感情の抑制-機能的磁気共鳴画像法（fMRI）を用いた検討-

飯田沙依亜, 田邊宏樹, 大平英樹, 金子一史

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： 3PM-115 - 3PM-115 2013年9月

社会脳研究の最前線―ハイパースキャニングによる共感/協調的コミュニケーション―

苧阪直行, 守田知代, 小池耕彦, 大平英樹, 大坊郁夫, 苧阪満里子

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： SS-045 - SS-045 2013年9月

罪悪感の喚起が主観，行動，生理反応に与える影響の検討

水上貴裕, 鈴木直人, 大平英樹

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： 1EV-073 - 1EV-073 2013年9月

抑制の逆説的効果がその後の怒り感情に及ぼす影響-顕在指標・潜在指標を用いて-

白根澤誉史, 南学, 大平英樹

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： 1EV-092 - 1EV-092 2013年9月

報酬予期における相対的価値の効果

遠山朝子, 大平英樹

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： 1AM-090 - 1AM-090 2013年9月

抑うつを可視化する心理学的マルチモーダルアプローチ

山本哲也, 熊野宏昭, 井澤修平, 山田真希子, 吉本潤一郎, 大平英樹

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： SS-053 - SS-053 2013年9月

サイコパシーと展望的・回想的記憶の関連

大庭丈幸, 大平英樹

日本心理学会大会発表論文集 77 巻 ( 0 ) 頁： 3EV-008 - 3EV-008 2013年9月

THE WEAPON FOCUS EFFECT REVISITED: PHYSICAL SHARPNESS OR EMOTION AROUSAL

Hamamoto Yuki, Hira Shinji, Ohira Hideki

PSYCHOPHYSIOLOGY 50 巻頁： S43 - S43 2013年9月

NEURAL MECHANISMS MEDIATING ASSOCIATION OF SYMPATHETIC ACTIVITY AND EXPLORATION IN DECISION MAKING

Ohira Hideki, Matsunaga Masahiro, Murakami Hiroki, Osumi Takahiro, Fukuyama Seisuke, Shinoda Jun, Yamada Jitsuhiro

PSYCHOPHYSIOLOGY 50 巻頁： S29 - S29 2013年9月

MODULATION OF DECISION-MAKING AND ACCOMPANYING PHYSIOLOGICAL RESPONSES BY ACUTE STRESS

Yamakawa Kaori, Matsunaga Masahiro, Isowa Tokiko, Ohira Hideki

PSYCHOPHYSIOLOGY 50 巻頁： S29 - S29 2013年9月

FLEXIBLE ADJUSTMENT OF ANTICIPATORY AFFECT BY RELATIVE VALUE

Toyama, A; Ohira, H

PSYCHOPHYSIOLOGY 50 巻頁： S29 - S29 2013年9月

Neural mechanisms mediating association of sympathetic activity and exploration in decision-making.

Ohira H, Matsunaga M, Murakami H, Osumi T, Fukuyama S, Shinoda J, Yamada J

Neuroscience 246 巻頁： 362 - 74 2013年8月

NEURAL MECHANISMS MEDIATING ASSOCIATION OF SYMPATHETIC ACTIVITY AND EXPLORATION IN DECISION-MAKING

Ohira H., Matsunaga M., Murakami H., Osumi T., Fukuyama S., Shinoda J., Yamada J.

NEUROSCIENCE 246 巻頁： 362 - 374 2013年8月

Neural mechanisms mediating association of sympathetic activity and exploration in decision-making 査読有り

H. Ohira, M. Matsunaga, H. Murakami, T. Osumi, S. Fukuyama, J. Shinoda, J. Yamada

Neuroscience 246 巻 ( 246 ) 頁： 362 - 374 2013年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

The somatic marker hypothesis asserts that decision-making can be guided by feedback of bodily states to the brain. In line with this hypothesis, the present study tested whether sympathetic activity shows an association with a tonic dimension of decision-making, exploratory tendency represented by entropy in information theory, and further examined the neural mechanisms of the association. Twenty participants performed a stochastic reversal learning task that required decision-making in an unstable and uncertain situation. Regional cerebral blood flow was evaluated using 15O-water positron emission tomography (PET), and cardiovascular indices and concentrations of catecholamine in peripheral blood were also measured, during the task. In reversal learning, increased epinephrine during the task positively correlated with larger entropy, indicating a greater tendency for exploration in decision-making. The increase of epinephrine also correlated with brain activity revealed by PET in the somatosensory cortices, anterior insula, dorsal anterior cingulate cortex, and the dorsal pons. This result is consistent with previously reported brain matrixes of representation of bodily states and interoception. In addition, activity of the anterior insula specifically correlated with entropy, suggesting possible mediation of this brain region between peripheral sympathetic arousal and exploration in decision-making. These findings shed a new light about a role of bodily states in decision-making and underlying neural mechanisms. © 2013 IBRO.

DOI： 10.1016/j.neuroscience.2013.04.050

Scopus

PubMed

Neural mechanisms mediating association of sympathetic activity and exploration in decision-making

Ohira H., Matsunaga M., Murakami H., Osumi T., Fukuyama S., Shinoda J., Yamada J.

Neuroscience 246 巻頁： 362 - 374 2013年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Neuroscience

DOI： 10.1016/j.neuroscience.2013.04.050

Scopus

Brain-Immune Interaction Accompanying Odor-Evoked Autobiographic Memory

Matsunaga Masahiro, Bai Yu, Yamakawa Kaori, Toyama Asako, Kashiwagi Mitsuyoshi, Fukuda Kazuyuki, Oshida Akiko, Sanada Kazue, Fukuyama Seisuke, Shinoda Jun, Yamada Jitsuhiro, Sadato Norihiro, Ohira Hideki

PLOS ONE 8 巻 ( 8 ) 2013年8月

Brain-Immune Interaction Accompanying Odor-Evoked Autobiographic Memory

Matsunaga M., Bai Y., Yamakawa K., Toyama A., Kashiwagi M., Fukuda K., Oshida A., Sanada K., Fukuyama S., Shinoda J., Yamada J., Sadato N., Ohira H.

PLoS ONE 8 巻 ( 8 ) 2013年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：PLoS ONE

The phenomenon in which a certain smell evokes a specific memory is known as the Proust phenomenon. Odor-evoked autobiographic memories are more emotional than those elicited by other sensory stimuli. The results of our previous study indicated that odor-evoked autobiographic memory accompanied by positive emotions has remarkable effects on various psychological and physiological activities, including the secretion of cytokines, which are immune-signaling molecules that modulate systemic inflammation. In this study, we aimed to clarify the neural substrates associated with the interaction between odor-evoked autobiographic memory and peripheral circulating cytokines. We recruited healthy male and female volunteers and investigated the association between brain responses and the concentration of several cytokines in the plasma by using positron emission tomography (PET) recordings when an autographic memory was evoked in participants by asking them to smell an odor that was nostalgic to them. Participants experienced positive emotions and autobiographic memories when nostalgic odors were presented to them. The levels of peripheral proinflammatory cytokines, such as the tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ), were significantly reduced after experiencing odor-evoked autobiographic memory. Subtraction analysis of PET images indicated that the medial orbitofrontal cortex (mOFC) and precuneus/posterior cingulate cortex (PCC) were significantly activated during experiences of odor-evoked autobiographic memory. Furthermore, a correlation analysis indicated that activities of the mOFC and precuneus/PCC were negatively correlated with IFN-γ concentration. These results indicate that the neural networks including the precuneus/PCC and mOFC might regulate the secretion of peripheral proinflammatory cytokines during the experience of odor-evoked autobiographic memories accompanied with positive emotions. © 2013 Matsunaga et al.

DOI： 10.1371/journal.pone.0072523

Scopus

Neural mechanisms mediating association of sympathetic activity and exploration in decision-making. 査読有り

Neuroscience ( 246 ) 頁： 362-374 2013年8月

Brain-Immune Interaction Accompanying Odor-Evoked Autobiographic Memory 査読有り

Masahiro Matsunaga, Yu Bai, Kaori Yamakawa, Asako Toyama, Mitsuyoshi Kashiwagi, Kazuyuki Fukuda, Akiko Oshida, Kazue Sanada, Seisuke Fukuyama, Jun Shinoda, Jitsuhiro Yamada, Norihiro Sadato, Hideki Ohira

PLOS ONE 8 巻 ( 8 ) 頁： e72523 2013年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：PUBLIC LIBRARY SCIENCE

The phenomenon in which a certain smell evokes a specific memory is known as the Proust phenomenon. Odor-evoked autobiographic memories are more emotional than those elicited by other sensory stimuli. The results of our previous study indicated that odor-evoked autobiographic memory accompanied by positive emotions has remarkable effects on various psychological and physiological activities, including the secretion of cytokines, which are immune-signaling molecules that modulate systemic inflammation. In this study, we aimed to clarify the neural substrates associated with the interaction between odor-evoked autobiographic memory and peripheral circulating cytokines. We recruited healthy male and female volunteers and investigated the association between brain responses and the concentration of several cytokines in the plasma by using positron emission tomography (PET) recordings when an autographic memory was evoked in participants by asking them to smell an odor that was nostalgic to them. Participants experienced positive emotions and autobiographic memories when nostalgic odors were presented to them. The levels of peripheral proinflammatory cytokines, such as the tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma), were significantly reduced after experiencing odor-evoked autobiographic memory. Subtraction analysis of PET images indicated that the medial orbitofrontal cortex (mOFC) and precuneus/posterior cingulate cortex (PCC) were significantly activated during experiences of odor-evoked autobiographic memory. Furthermore, a correlation analysis indicated that activities of the mOFC and precuneus/PCC were negatively correlated with IFN-gamma concentration. These results indicate that the neural networks including the precuneus/PCC and mOFC might regulate the secretion of peripheral proinflammatory cytokines during the experience of odor-evoked autobiographic memories accompanied with positive emotions.

DOI： 10.1371/journal.pone.0072523

Web of Science

Vagal nerve activity as a moderator of brain-immune relationships.

Ohira H, Matsunaga M, Osumi T, Fukuyama S, Shinoda J, Yamada J, Gidron Y

Journal of neuroimmunology 260 巻 ( 1-2 ) 頁： 28 - 36 2013年7月

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