-
Maternal progesterone and adipose mPRε in pregnancy regulate the embryonic nutritional state.
Watanabe K, Yamano M, Miyamoto J, Ohue-Kitano R, Masujima Y, Sasahara D, Mouri Y, Kono N, Inuki S, Osakada F, Nagaoka K, Aoki J, Sugiura Y, Ohno H, Kondoh E, Kimura I
Cell reports
Vol.
44
(
3
)
page：
115433
2025.3
-
Conversion of silent synapses to AMPA receptor-mediated functional synapses in human cortical organoids
Nishimura, M; Kodera, T; Adachi, S; Sato, AY; Takeuchi, RF; Nonaka, H; Hamachi, I; Osakada, F
NEUROSCIENCE RESEARCH
Vol.
212
page：
20
-
30
2025.3
-
Bridge protein-mediated viral targeting of cells expressing endogenous μ-opioid G protein-coupled receptors in the mouse and monkey brain.
Kamaguchi R, Amemori S, Amemori KI, Osakada F
Neuroscience research
2025.2
-
Involvement of nuclear receptor corepressor 2 (NCOR2) in estrogen-induced repression of arcuate Kiss1 expression in female rats.
Takizawa M, Miyazaki S, Tsuchida H, Nagae M, Seki S, Hirabayashi M, Osakada F, Inoue N, Tsukamura H, Uenoyama Y
The Journal of reproduction and development
2025.1
-
Evolutionary engineering and characterization of Sendai virus mutants capable of persistent infection and autonomous production
Iwata, M; Kawabata, R; Morimoto, N; Takeuchi, RF; Sakaguchi, T; Irie, T; Osakada, F
FRONTIERS IN VIROLOGY
Vol.
4
2024.4
-
Differential second messenger signaling via dopamine neurons bidirectionally regulates memory retention.
Reviewed
Mai Takakura, Yu Hong Lam, Reiko Nakagawa, Man Yung Ng, Xinyue Hu, Priyanshu Bhargava, Abdalla G Alia, Yuzhe Gu, Zigao Wang, Takeshi Ota, Yoko Kimura, Nao Morimoto, Fumitaka Osakada, Ah Young Lee, Danny Leung, Tomoyuki Miyashita, Juan Du, Hiroyuki Okuno, Yukinori Hirano
Proceedings of the National Academy of Sciences of the United States of America
Vol.
120
(
36
)
page：
e2304851120
2023.8
-
Modeling the marmoset brain using embryonic stem cell-derived cerebral assembloids
Kodera Tomoki, Takeuchi Ryosuke F., Takahashi Sara, Suzuki Keiichiro, Kassai Hidetoshi, Aiba Atsu, Shiozawa Seiji, Okano Hideyuki, Osakada Fumitaka
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Vol.
657
page：
119
-
127
2023.5
-
Generation and Application of Engineered Rabies Viral Vectors for Neural Circuit Research
Invited
Reviewed
Yamaguchi M*, Iwata M*, Kamaguchi R*, Osakada F
Vectorology for Optogenetics and Chemogenetics
page：
51
-
75
2023.2
-
[Interdisciplinary approaches to brain organoid biology].
Kodera T, Osakada F
Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Vol.
158
(
1
)
page：
64
-
70
2023
-
Fast z-focus controlling and multiplexing strategies for multiplane two-photon imaging of neural dynamics
Ito Kei N., Isobe Keisuke, Osakada Fumitaka
NEUROSCIENCE RESEARCH
Vol.
179
page：
15
-
23
2022.6
-
Monosynaptic rabies virus tracing from projection-targeted single neurons
Masaki Yuji, Yamaguchi Masahiro, Takeuchi Ryosuke F., Osakada Fumitaka
NEUROSCIENCE RESEARCH
Vol.
178
page：
20
-
32
2022.5
-
Temporally multiplexed dual-plane imaging of neural activity with four-dimensional precision
Onda Masanari, Takeuchi Ryosuke F., Isobe Keisuke, Suzuki Toshiaki, Masaki Yuji, Morimoto Nao, Osakada Fumitaka
NEUROSCIENCE RESEARCH
Vol.
171
page：
9
-
18
2021.10
-
Cell type- and layer-specific convergence in core and shell neurons of the dorsal lateral geniculate nucleus
Okigawa Sayumi, Yamaguchi Masahiro, Ito Kei N., Takeuchi Ryosuke F., Morimoto Nao, Osakada Fumitaka
JOURNAL OF COMPARATIVE NEUROLOGY
Vol.
529
(
8
)
page：
2099
-
2124
2021.6
-
Efficient and robust induction of retinal pigment epithelium cells by tankyrase inhibition regardless of the differentiation propensity of human induced pluripotent stem cells
Ito Arisa, Ye Ke, Onda Masanari, Morimoto Nao, Osakada Fumitaka
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Vol.
552
page：
66
-
72
2021.5
-
Reproducible production and image-based quality evaluation of retinal pigment epithelium sheets from human induced pluripotent stem cells
Ye Ke, Takemoto Yuto, Ito Arisa, Onda Masanari, Morimoto Nao, Mandai Michiko, Takahashi Masayo, Kato Ryuji, Osakada Fumitaka
SCIENTIFIC REPORTS
Vol.
10
(
1
)
page：
14387
2020.9
-
Multiplex Neural Circuit Tracing With G-Deleted Rabies Viral Vectors
Suzuki Toshiaki, Morimoto Nao, Akaike Akinori, Osakada Fumitaka
FRONTIERS IN NEURAL CIRCUITS
Vol.
13
page：
77
2020.1
-
[Circuit mechanisms of spatial perception and visuomotor integration].
Takeuchi RF, Osakada F
Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Vol.
155
(
2
)
page：
99
-
106
2020
-
[Preface].
Osakada F, Sakamoto K
Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Vol.
155
(
2
)
page：
80
2020
-
Role of dynamic nuclear deformation on genomic architecture reorganization
Seirin-Lee Sungrim, Osakada Fumitaka, Takeda Junichi, Tashiro Satoshi, Kobayashi Ryo, Yamamoto Takashi, Ochiai Hiroshi
PLOS COMPUTATIONAL BIOLOGY
Vol.
15
(
9
)
page：
e1007289
2019.9
-
Tracing of Afferent Connections in the Zebrafish Cerebellum Using Recombinant Rabies Virus
Dohaku Ryuji, Yamaguchi Masahiro, Yamamoto Naoyuki, Shimizu Takashi, Osakada Fumitaka, Hibi Masahiko
FRONTIERS IN NEURAL CIRCUITS
Vol.
13
page：
30
2019.4
-
Intersectional monosynaptic tracing for dissecting subtype-specific organization of GABAergic interneuron inputs
Yetman Michael J., Washburn Eric, Hyun Jung Ho, Osakada Fumitaka, Hayano Yasufumi, Zeng Hongkui, Callaway Edward M., Kwon Hyung-Bae, Taniguchi Hiroki
NATURE NEUROSCIENCE
Vol.
22
(
3
)
page：
492
-
+
2019.3
-
Centrifugal Inputs to the Main Olfactory Bulb Revealed Through Whole Brain Circuit-Mapping
Padmanabhan Krishnan, Osakada Fumitaka, Tarabrina Anna, Kizer Erin, Callaway Edward M., Gage Fred H., Sejnowski Terrence J.
FRONTIERS IN NEUROANATOMY
Vol.
12
page：
115
2019.1
-
[Cell-type-specific targeting strategies for elucidating neural circuits and pathophysiological mechanisms in the marmoset brain].
Hara T, Osakada F
Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Vol.
153
(
5
)
page：
210
-
218
2019
-
The Cutting Edge of Retinal Circuit Research
Osakada Fumitaka, Koike Chieko
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
Vol.
138
(
5
)
page：
667
-
668
2018.5
-
Viral and Electrophysiological Approaches for Elucidating the Structure and Function of Retinal Circuits
Onda Masanari, Sansawa Kouki, Osakada Fumitaka
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
Vol.
138
(
5
)
page：
669
-
678
2018.5
-
[The Cutting Edge of Retinal Circuit Research].
Osakada F, Koike C
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Vol.
138
(
5
)
page：
667
-
668
2018
-
[Viral and Electrophysiological Approaches for Elucidating the Structure and Function of Retinal Circuits].
Onda M, Sansawa K, Osakada F
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Vol.
138
(
5
)
page：
669
-
678
2018
-
Development of Cellular and Tissue-based Products for Retinal Regenerative Medicine
Osakada Fumitaka
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN
Vol.
137
(
1
)
page：
23
-
29
2017.1
-
Development of Cellular and Tissue-based Products for Retinal Regenerative Medicine.
Osakada F
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Vol.
137
(
1
)
page：
23
-
29
2017
-
Toward understanding structure and function of neural circuits in the visual system.
Onda M, Osakada F
Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Vol.
149
(
6
)
page：
274
-
280
2017
-
新規手法が切り拓く神経回路研究の新時代
小坂田文隆
化学と生物
Vol.
53
(
10
)
page：
673-680
2015.9
-
神経回路の構造と機能を明らかにする新規G欠損狂犬病ウイルストレーシング法
小坂田文隆
日本薬理学雑誌
Vol.
146
(
2
)
page：
98-105 (J-STAGE)
2015.8
-
A dedicated circuit links direction-selective retinal ganglion cells to the primary visual cortex.
Reviewed
Cruz-Martín A, El-Danaf RN, Osakada F, Sriram B, Dhande OS, Nguyen PL, Callaway EM, Ghosh A, Huberman AD
Nature
Vol.
507
page：
358-361
2014.3
-
Design and generation of recombinant rabies virus vectors.
Reviewed
Osakada F, Callaway EM
Nature protocols
Vol.
8
page：
1583-1601
2013.8
-
Imaging light responses of retinal ganglion cells in the living mouse eye.
Reviewed
Yin L, Geng Y, Osakada F, Sharma R, Cetin AH, Callaway EM, Williams DR, Merigan WH
Journal of neurophysiology
Vol.
109
page：
2415-2421
2013.5
-
iPS細胞を用いた網膜変性疾患の病態解析と創薬研究
小坂田文隆
ファルマシア
Vol.
48
(
9
)
page：
842-846
2012.9
-
Defining the integration capacity of embryonic stem cell-derived photoreceptor precursors.
Reviewed
West EL, Gonzalez-Cordero A, Hippert C, Osakada F, Martinez-Barbera JP, Pearson RA, Sowden JC, Takahashi M, Ali RR
Stem cells
Vol.
30
(
7
)
page：
1424-1435
2012.7
-
New rabies virus variants for monitoring and manipulating activity and gene expression in defined neural circuits.
Reviewed
Osakada F, Mori T, Cetin AH, Marshel JH, Virgen B, Callaway EM
Neuron
Vol.
71
(
4
)
page：
617-631
2011.8
-
Neural induction and patterning in mammalian pluripotent stem cells.
Reviewed
Osakada F, Takahashi M
CNS & neurological disorders drug targets
Vol.
10
page：
419-432
2011.6
-
Modeling retinal degeneration using patient-specific induced pluripotent stem cells.
Reviewed
Jin ZB, Okamoto S, Osakada F, Homma K, Assawachananont J, Hirami Y, Iwata T, Takahashi M
PloS one
Vol.
6
page：
e17084
2011.2
-
Nuclear reprogramming to treat retinal degenerative diseases
Reviewed
Osakada F
Inflammation and Regeneration
Vol.
31
page：
33-49
2011.1
-
網膜神経細胞死の再生・分化を制御する因子
赤池昭紀, 久米利明, 泉安彦, 小坂田文隆
日本薬理学雑誌
Vol.
135
(
4
)
page：
142-145
2010.4
-
In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction.
Reviewed
Osakada F, Jin ZB, Hirami Y, Ikeda H, Danjyo T, Watanabe K, Sasai Y, Takahashi M
Journal of cell science
Vol.
122
(
17
)
page：
3169-3179
2009.9
-
ヒトES細胞・iPS細胞の分化誘導技術の開発―眼疾患への治療応用の可能性―
小坂田文隆, 高橋政代
iPS細胞の産業的応用技術
page：
169-179
2009.9
-
Detection of localized retinal malfunction in retinal degeneration model using a multielectrode array system.
Reviewed
Homma K, Osakada F, Hirami Y, Jin ZB, Mandai M, Takahashi M
Journal of neuroscience research
Vol.
87
page：
2175-2182
2009.7
-
Stepwise differentiation of pluripotent stem cells into retinal cells.
Reviewed
Osakada F, Ikeda H, Sasai Y, Takahashi M
Nature protocols
Vol.
4
page：
811-824
2009
-
ES細胞からの神経分化誘導
小坂田文隆, 高橋政代
培養細胞実験ハンドブック
page：
291-296
2008.12
-
網膜における幹細胞生物学--発生・再生・エイジング (あゆみ 再生医療とアンチエイジング)
小坂田文隆, 高橋政代
医学のあゆみ
Vol.
224
(
7
)
page：
511-517
2008.2
-
Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells.
Reviewed
Osakada F, Ikeda H, Mandai M, Wataya T, Watanabe K, Yoshimura N, Akaike A, Sasai Y, Takahashi M
Nature biotechnology
Vol.
26
(
2
)
page：
215-224
2008.2
-
成体網膜の再生機構における Wnt シグナルの役割
小坂田文隆, 赤池昭紀, 高橋政代
眼薬理 = Japanese journal of ocular pharmacology
Vol.
21
(
1
)
page：
84-86
2007.8
-
ミューラーグリアが網膜を再生する (特集 中枢神経の機能再生--細胞治療と人工臓器)
小坂田文隆
メディカルバイオ
Vol.
4
(
5
)
page：
30-35
2007.7
-
幹細胞技術の現状と展望(9)中枢神経系における幹細胞治療--網膜再生をめざして
小坂田文隆, 高橋政代
蛋白質核酸酵素
Vol.
52
(
5
)
page：
470-477
2007.5
-
Wnt signaling promotes regeneration in the retina of adult mammals.
Reviewed
Osakada F, Ooto S, Akagi T, Mandai M, Akaike A, Takahashi M
The Journal of neuroscience
Vol.
27
page：
4210-4219
2007.4
-
Neural conversion of ES cells by an inductive activity on human amniotic membrane matrix.
Reviewed
Ueno M, Matsumura M, Watanabe K, Nakamura T, Osakada F, Takahashi M, Kawasaki H, Kinoshita S, Sasai Y
Proceedings of the National Academy of Sciences of the United States of America
Vol.
103
(
25
)
page：
9554-9559
2006.6
-
体性幹細胞を用いた網膜再生
小坂田文隆, 高橋政代
実験医学
Vol.
24
(
2
)
page：
256-264
2006.1
-
ビタミンE類縁体の神経保護作用
小坂田文隆, 久米利明, 赤池昭紀
医学のあゆみ
Vol.
215
(
8
)
page：
705-706
2005.11
-
Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cells.
Reviewed
Ikeda H, Osakada F, Watanabe K, Mizuseki K, Haraguchi T, Miyoshi H, Kamiya D, Honda Y, Sasai N, Yoshimura N, Takahashi M, Sasai Y
Proceedings of the National Academy of Sciences of the United States of America
Vol.
102
(
32
)
page：
11331-11336
2005.8
-
Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons.
Reviewed
Osakada F, Hashino A, Kume T, Katsuki H, Kaneko S, Akaike A
Neuropharmacology
Vol.
47
page：
904-915
2004.11
-
Serofendic acid, a sulfur-containing diterpenoid derived from fetal calf serum, attenuates reactive oxygen species-induced oxidative stress in cultured striatal neurons.
Reviewed
Osakada F, Kawato Y, Kume T, Katsuki H, Sugimoto H, Akaike A
The Journal of pharmacology and experimental therapeutics
Vol.
311
page：
51-59
2004.10
-
Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum.
Reviewed
Kume T, Asai N, Nishikawa H, Mano N, Terauchi T, Taguchi R, Shirakawa H, Osakada F, Mori H, Asakawa N, Yonaga M, Nishizawa Y, Sugimoto H, Shimohama S, Katsuki H, Kaneko S, Akaike A
Proceedings of the National Academy of Sciences of the United States of America
Vol.
99
(
5
)
page：
3288-3293
2002.3
