Updated on 2024/04/01

写真a

 
OHASHI Yuki
 
Organization
Graduate School of Medicine Assistant Professor
Undergraduate School
School of Health Sciences
Title
Assistant Professor
External link

Degree 1

  1. 博士(薬学) ( 2023.3   東京薬科大学 ) 

Research Interests 3

  1. Uric acid

  2. トランスポーター

  3. 疫学

Research Areas 1

  1. Life Science / Nephrology

Education 2

  1. Tokyo University of Pharmacy and Life Science

    2019.4 - 2023.3

  2. Tokyo University of Pharmacy and Life Science

    2013.4 - 2019.3

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    Country: Japan

Awards 1

  1. 最優秀演題賞

    2023.3   日本痛風・尿酸核酸学会  

 

Papers 6

  1. Plasma and Urinary Metabolomic Analysis of Gout and Asymptomatic Hyperuricemia and Profiling of Potential Biomarkers: A Pilot Study. Reviewed

    Yuki Ohashi, Hiroshi Ooyama, Hideki Makinoshima, Tappei Takada, Hirotaka Matsuo, Kimiyoshi Ichida

    Biomedicines   Vol. 12 ( 2 )   2024.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/biomedicines12020300

  2. Urate Transporter ABCG2 Function and Asymptomatic Hyperuricemia: A Retrospective Cohort Study of CKD Progression. Reviewed

    Yuki Ohashi, Satoru Kuriyama, Tomoko Nakano, Mai Sekine, Yu Toyoda, Akiyoshi Nakayama, Tappei Takada, Yusuke Kawamura, Takahiro Nakamura, Hirotaka Matsuo, Takashi Yokoo, Kimiyoshi Ichida

    American journal of kidney diseases   Vol. 81 ( 2 ) page: 134 - 144   2023.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1053/j.ajkd.2022.05.010

  3. Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients. Reviewed

    Yuki Ohashi, Masao Toyoda, Nobumichi Saito, Masahiro Koizumi, Genta Kanai, Hirotaka Komaba, Moritsugu Kimura, Takehiko Wada, Hiroo Takahashi, Yuichiro Takahashi, Naoto Ishida, Takatoshi Kakuta, Masafumi Fukagawa, Kimiyoshi Ichida

    Scientific reports   Vol. 13 ( 1 ) page: 93 - 93   2023.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-022-26519-x

  4. Analysis of Purine Metabolism to Elucidate the Pathogenesis of Acute Kidney Injury in Renal Hypouricemia. Reviewed International coauthorship

    Daisuke Miyamoto, Nana Sato, Koji Nagata, Yukinao Sakai, Hitoshi Sugihara, Yuki Ohashi, Blanka Stiburkova, Ivan Sebesta, Kimiyoshi Ichida, Ken Okamoto

    Biomedicines   Vol. 10 ( 7 )   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/biomedicines10071584

  5. Renal hypouricemia in a recipient of living-donor kidney transplantation: a case report and literature review. Reviewed

    Takamasa Miyauchi, Maho Terashita, Masatomo Ogata, Marie Murata, Kiyomi Osako, Naohiko Imai, Yuko Sakurai, Hideo Sasaki, Yuki Ohashi, Kimiyoshi Ichida, Yugo Shibagaki, Masahiko Yazawa

    CEN case reports   ( 2 ) page: 177 - 183   2022.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s13730-021-00647-1

  6. Dysfunctional ABCG2 gene polymorphisms are associated with serum uric acid levels and all-cause mortality in hemodialysis patients. Reviewed

    Akio Nakashima, Kimiyoshi Ichida, Ichiro Ohkido, Keitaro Yokoyama, Hirotaka Matsuo, Yuki Ohashi, Tappei Takada, Akiyoshi Nakayama, Hiroshi Suzuki, Nariyoshi Shinomiya, Mitsuyoshi Urashima, Takashi Yokoo

    Human cell   Vol. 33 ( 3 ) page: 559 - 568   2020.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s13577-020-00342-w

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Presentations 8

  1. 遊離アミノ酸プロファイルを用いた血清尿酸値の規定因子の探索

    大橋勇紀, 市田公美

    第57回日本痛風・尿酸核酸学会総会  2024.2.29 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  2. Relation of Urate Transporter ABCG2 Function with Asymptomatic Hyperuricemia and Hypouricemia: A Retrospective Cohort Study of CKD Progression. International conference

    Yuki Ohashi, Satoru Kuriyama, Tomoko Nakano, Kimiyoshi Ichida

    FEBS Special Meeting 2023 ATP-Binding Cassette (ABC) Proteins: From multidrug Resistance to Genetic Disease  2023.3.1 

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    Language:English   Presentation type:Poster presentation  

    Country:Austria  

  3. Identification of Potential Biomarkers for the Progression from Asymptomatic Hyperuricemia to Gout using Plasma and Urinary Metabolomics. International conference

    Yuki Ohashi, Hiroshi Oyama, Hideki Makinoshima, Kimiyoshi Ichida

    24th Asia-Pacific League of Associations for Rheumatology Congress  2022.12 

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    Language:English   Presentation type:Poster presentation  

    Country:Hong Kong  

  4. ABCG2 による腎外尿酸排泄量の推定

    大橋勇紀, 豊田雅夫, 市田公美

    第 65 回日本腎臓学会学術総会  2022.6.11 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  5. 健常人における腎機能と ABCG2 機能低下の関係

    大橋勇紀, 中野知子, 栗山啓, 市田公美

    第 64 回日本腎臓学会学術総会  2021.6.19 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

  6. Decreased ABCG2 Activity Accelerates the Age-Dependent Decline in Renal Function. International conference

    Yuki Ohashi, Satoru Kuriyama, Kimiyoshi Ichida

    The 19th International Purine and Pyrimidine Symposium (online)  2021.6.15 

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    Language:English   Presentation type:Oral presentation (general)  

  7. Renoprotective Effects of Urate Transporter ABCG2 in CKD patients International conference

    Yuki Ohashi, Shunya Uchida, Tappei Takada, Hirotaka Matsuo, Shigeru Shibata, Kimiyoshi Ichida

    FEBS Special Meeting 2020 ATP-Binding Cassette (ABC) Proteins: From multidrug Resistance to Genetic Disease  2020.3.5 

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    Language:English   Presentation type:Poster presentation  

    Country:Austria  

  8. CKD 患者に及ぼす尿酸トランスポーターABCG2 の保護的役割の解明

    大橋勇紀, 柴田茂, 高田龍平, 松尾洋孝, 内田俊也, 市田公美

    第 53 回日本痛風・尿酸核酸学会総会  2020.2.13 

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    Language:Japanese   Presentation type:Oral presentation (general)  

    Country:Japan  

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Research Project for Joint Research, Competitive Funding, etc. 1

  1. 分子遺伝疫学解析による尿酸トランスポーター機能と腎機能との関連性の解明

    2023.4 - 2025.3

    日本痛風・尿酸核酸学会 若手研究助成 

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    Authorship:Principal investigator 

    Grant amount:\200000

KAKENHI (Grants-in-Aid for Scientific Research) 1

  1. 尿酸トランスポーターの一塩基多型に着目した尿路結石症発症のリスク評価

    Grant number:23K19387  2023 - 2025.3

    文部科学省  日本学術振興会 科学研究費助成事業 研究活動スタート支援 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2860000 ( Direct Cost: \2200000 、 Indirect Cost:\660000 )