Updated on 2026/03/17

写真a

 
KATO Teruyo
 
Organization
Graduate School of Bioagricultural Sciences Department of Applied Biosciences Associate Professor
Graduate School
Graduate School of Bioagricultural Sciences
Undergraduate School
School of Agricultural Sciences Department of Applied Biosciences
Title
Associate Professor
External link

Degree 1

  1. 博士(農学) ( 2013.3   名古屋大学 ) 

Research Areas 3

  1. Life Science / Applied microbiology

  2. Life Science / Molecular biology

  3. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Applied biofunctional and bioprocess engineering  / Protein

Current Research Project and SDGs 3

  1. bio-production

  2. Microorganism

  3. Protein

Professional Memberships 3

  1. The Society for Biotechnology, Japan

  2. Japanese Society for Bioscience, Biotechnology, and Agrochemistry

  3. 日本蛋白質科学会

Committee Memberships 1

  1.   2023年度生物工学若手研究者の集い(若手会)夏のセミナー 実行委員  

    2023.6   

      More details

    Committee type:Academic society

Awards 10

  1. 第25回酵素応用シンポジウム研究奨励賞

    2024.6   一般財団法人天野エンザイム科学技術振興財団   翻訳促進技術の開発とタンパク質生産・機能評価への応用

    加藤晃代

     More details

    Award type:Award from publisher, newspaper, foundation, etc. 

  2. JSBBA Award for Young Scientists

    2024.3  

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

  3. バイオインダストリー奨励賞

    2023.10   日本バイオインダストリー協会   翻訳効率を向上させるペプチドに関する研究

    加藤晃代

     More details

    Award type:Award from publisher, newspaper, foundation, etc. 

  4. 第20回農芸化学企画賞

    2023.3   日本農芸化学会   翻訳を促進する新生ペプチドの探索とタンパク質生産への産業応用

    加藤晃代

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

    本賞は、実学である農芸化学分野らしい優れた研究企画に対するユニークな賞です。農芸化学の特徴を活かした研究領域で、萌芽的研究および産業化を模索する比較的早期の研究の企画を対象とします。

  5. 第17回わかしゃち奨励賞応用研究部門優秀賞

    2023.1   愛知県、公益財団法人科学技術交流財団、公益財団法人日比科学技術振興財団   微生物によるマルチ機能抗体の生産技術開発

    加藤晃代

     More details

    愛知県、(公財)科学技術交流財団及び(公財)日比科学技術振興財団が共同し、全国の優秀な若手研究者から、新たな経済価値をもたらす革新的な基礎研究や産業の高度化・発展、社会的課題の解決につながる夢のある研究テーマ・アイデアを募集し、授与するもの。

  6. 日本生物工学会技術賞

    2018.9   日本生物工学会   無細胞タンパク質合成系を利用した迅速抗体スクリーニング技術開発とその実用化

    加藤 晃代, 中野 秀雄, 兒島 孝明, 永井 里美

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

  7. 日本生物工学会論文賞

    2018.9   日本生物工学会   N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae

    加藤晃代、永井里美、中野秀雄

  8. Paper award

    2018.9   N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae

    Ojima-Kato, T, Nagai, S, Nakano, H

  9. 日本生物工学会中部支部支部長賞

    2017.9   日本生物工学会中部支部   N 末端 SKIK ペプチドタグによるタンパク質発現増大に関する研究

    加藤晃代

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

  10. 若手女性研究者賞

    2017.3   日本農芸化学会   有用タンパク質の微生物生産とその産業利用に関する研究

    加藤晃代

     More details

    Award type:Award from Japanese society, conference, symposium, etc. 

▼display all

 

Papers 37

  1. Development of monoclonal antibody targeting membrane protein utilizing modified Ecobody technology Reviewed

    Daffa Sean Adinegoro, Teruyo Ojima-Kato, Hideo Nakano

    Journal of Bioscience and Bioengineering   Vol. 141 ( 4 ) page: 237 - 245   2026.4

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.jbiosc.2025.12.001

    Scopus

    PubMed

  2. A strategy for scalable antibody production: the combination of <i>Escherichia coli</i> expression, translation-enhancing peptide and automated refolding system Open Access

    Tung Anh Hoang, Hideo Nakano, Teruyo Ojima-Kato

    Bioscience, Biotechnology, and Biochemistry   Vol. 90 ( 3 ) page: 429 - 437   2025.12

     More details

    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Oxford University Press (OUP)  

    Abstract

    Monoclonal antibodies are essential tools in biological research, diagnostics, and therapeutics. While mammalian expression systems are widely used, microbial hosts such as Escherichia coli offer cost-effective and scalable production of antibody fragments but often yield inclusion bodies requiring refolding. In this study, we report a combined strategy using a translation-enhancing SKIK peptide tag and a leucine zipper-fused Fab format to improve expression in Escherichia coli, together with a continuous, dialysis-based automated refolding system. Compared with the conventional stepwise method, the automated process recovered model antibodies with equivalent antigen-binding activity and refolding yield (approximately 98%), while reducing processing time to 40%, waste volume to 69%, and chemical consumption to 47% of the modified stepwise process. The apparatus is simple to set up and operate, making it applicable from laboratory to industrial scales. This resource-efficient and scalable approach provides a practical alternative for scalable antibody fragment production in microbial systems.

    DOI: 10.1093/bbb/zbaf197

    Open Access

    Scopus

    PubMed

    Other Link: https://academic.oup.com/bbb/article-pdf/90/3/429/66123715/zbaf197.pdf

  3. Screening and machine learning-based prediction of translation-enhancing peptides that reduce ribosomal stalling in Escherichia coli. Reviewed International journal Open Access

    Teruyo Ojima-Kato, Gentaro Yokoyama, Hideo Nakano, Michiaki Hamada, Chie Motono

    RSC chemical biology   Vol. 7 ( 1 ) page: 58 - 66   2025.10

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    We previously reported that the nascent SKIK peptide enhances translation and alleviates ribosomal stalling caused by arrest peptides (APs) such as SecM and polyproline when positioned immediately upstream of the APs in both Escherichia coli in vivo and in vitro translation systems. In this study, we conducted a comprehensive screening of translation-enhancing peptides (TEPs) using a randomized artificial tetrapeptide library. The screening focused on the ability of the peptides to suppress SecM AP-induced translational stalling in E. coli cells. We identified TEPs exhibiting a range of translation-enhancing activities. In vitro translation analysis suggested that the fourth amino acid in the tetrapeptide influences the reduction of SecM AP-mediated stalling. Additionally, we developed a machine learning model using a random forest algorithm to predict TEP activity, which showed a strong correlation with experimentally measured activities. These findings provide a compact peptide toolkit and a data-driven approach for alleviating AP-induced ribosome stalling, with potential applications in synthetic biology.

    DOI: 10.1039/d5cb00199d

    Open Access

    Scopus

    PubMed

  4. Analysis and Application of Translation-Enhancing Peptides for Improved Production of Proteins Containing Polyproline Reviewed

    Akimichi Yoshino, Riko Shimoji, Yuma Nishikawa, Hideo Nakano, Teruyo Ojima-Kato

    SynBio   Vol. 3 ( 4 ) page: 14 - 14   2025.10

     More details

    Authorship:Last author, Corresponding author   Publishing type:Research paper (scientific journal)   Publisher:MDPI AG  

    Polyproline residues are well known to induce ribosomal stalling during translation. Our previous work demonstrated that inserting a short translation-enhancing peptide, Ser-Lys-Ile-Lys (SKIK), immediately upstream of such difficult-to-translate sequences can significantly alleviate ribosomal stalling in Escherichia coli. In this study, we provide a quantitative evaluation of its translational effect by kinetically analyzing the influence of the SKIK peptide on polyproline motifs using a reconstituted E. coli in vitro translation system. Translation rates estimated under reasonable assumptions fitted well to a Hill equation within a Michaelis–Menten-like kinetic framework. We further revealed that repetition of the SKIK tag did not provide any positive effect on translation. Moreover, introduction of the SKIK tag increased the production of polyproline-containing proteins, including human interleukin 11, human G protein signaling modulator 3, and DUF58 domain–containing protein from Streptomyces sp. in E. coli cell-free protein synthesis. These findings not only provide new insight into the fundamental regulation of translation by nascent peptides but also demonstrate the potential of the SKIK peptide as a practical tool for synthetic biology, offering a strategy to improve the production of difficult-to-express proteins.

    DOI: 10.3390/synbio3040014

  5. Evaluation of antibody variants using a ribosome display and Brevibacillus choshinensis secretion system. Reviewed

    Journal of Bioscience and Bioengineering     2025.3

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1016/j.jbiosc.2025.02.009

  6. Effect of translation enhancing nascent SKIK peptide on the arrest peptides containing consecutive proline. Reviewed Open Access

    Nishikawa, Y., Fujikawa, R., Nakano, H., Kanamori, T. and Ojima-Kato, T.

      Vol. 13 ( 12 ) page: 3908 - 3916   2024.11

     More details

    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1021/acssynbio.4c00221

    Open Access

  7. Glu592 of the axon guidance receptor ROBO3 mediates a pH-dependent interaction with NELL2 ligand Reviewed Open Access

    Mizutani, K., Toyoda, M., Ojima-Kato, T., Maturana, A.D. and Niimi, T.

    FEBS Letters   Vol. 599 ( 4 ) page: 571 - 580   2024.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1002/1873-3468.15054

    Open Access

  8. Advances in recombinant protein production in microorganisms and functional peptide tags Reviewed

    Teruyo Ojima-Kato

    Bioscience, Biotechnology, and Biochemistry   Vol. 89 ( 1 ) page: 1 - 10   2024.10

     More details

    Authorship:Lead author, Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1093/bbb/zbae147

  9. Rapid and cost-effective epitope mapping using PURE ribosome display coupled with next-generation sequencing and bioinformatics Reviewed Open Access

      Vol. 137 ( 4 ) page: 321 - 328   2024.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2024.01.008

  10. Nascent MSKIK peptide cancels ribosomal stalling by arrest peptides in Escherichia coli Reviewed Open Access

      Vol. 299 ( 5 ) page: 104676   2023.4

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1016/j.jbc.2023.104676

    Open Access

  11. Proteotyping of Campylobacter jejuni by MALDI-TOF MS and Strain Solution Version 2 Software Reviewed Open Access

    Ojima-Kato, T. , Nagai, S., Fujita, A., Sakata, J., Tamura, H.

    Microorganisms   Vol. 11 ( 1 ) page: 202   2023.1

     More details

    Authorship:Lead author, Corresponding author   Language:English  

    DOI: https://doi.org/10.3390/microorganisms11010202

    Open Access

  12. Improved MALDI-MS method for the highly sensitive and reproducible detection of biomarker peaks for the proteotyping of Salmonella serotypes.

    Fukuyama Y, Ojima-Kato T, Nagai S, Shima K, Funatsu S, Yamada Y, Tamura H, Nomura S, Ogata K, Sekiya S, Iwamoto S, Tanaka K

    Journal of mass spectrometry : JMS   Vol. 54 ( 12 ) page: 966 - 975   2019.12

     More details

    Language:English  

    DOI: 10.1002/jms.4469

    PubMed

  13. Rapid Generation of Monoclonal Antibodies from Single B Cells by Ecobody Technology Open Access

    Ojima-Kato Teruyo, Morishita Shiomi, Uchida Yoshino, Nagai Satomi, Kojima Takaaki, Nakano Hideo

    ANTIBODIES   Vol. 7 ( 4 )   2018.12

     More details

  14. SKIK-zipbody-alkaline phosphatase, a novel antibody fusion protein expressed in Escherichia coli cytoplasm

    Ritthisan Panwad, Ojima-Kato Teruyo, Damnjanovic Jasmina, Kojima Takaaki, Nakano Hideo

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 126 ( 6 ) page: 705 - 709   2018.12

     More details

  15. Zipbodyzyme: Development of new antibody-enzyme fusion proteins Reviewed

    Akihiro Mori, Teruyo Ojima-Kato, Takaaki Kojima, Hideo Nakano

    Journal of Bioscience and Bioengineering   Vol. 125 ( 6 ) page: 637 - 643   2018.6

     More details

    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Elsevier B.V.  

    DOI: 10.1016/j.jbiosc.2017.12.021

    Scopus

    PubMed

  16. Application of proteotyping Strain Solution™ ver. 2 software and theoretically calculated mass database in MALDI-TOF MS typing of Salmonella serotype.

    Ojima-Kato T, Yamamoto N, Nagai S, Shima K, Akiyama Y, Ota J, Tamura H

    Applied microbiology and biotechnology   Vol. 101 ( 23-24 ) page: 8557 - 8569   2017.12

     More details

    Language:English  

    DOI: 10.1007/s00253-017-8563-3

    PubMed

  17. Development of a rapid immunoassay system: Luminescent detection of antigen-associated antibody-luciferase in the presence of a dye that absorbs light from free antibody-luciferase.

    Mori A, Ojima-Kato T, Fuchi S, Kaiya S, Kojima T, Nakano H

    Journal of bioscience and bioengineering   Vol. 124 ( 6 ) page: 694 - 699   2017.12

     More details

    Language:English  

    DOI: 10.1016/j.jbiosc.2017.06.016

    PubMed

  18. Ecobody technology: rapid monoclonal antibody screening method from single B cells using cell-free protein synthesis for antigen-binding fragment formation Open Access

    Ojima-Kato Teruyo, Nagai Satomi, Nakano Hideo

    SCIENTIFIC REPORTS   Vol. 7 ( 1 ) page: 13979   2017.10

  19. N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae.

    Ojima-Kato T, Nagai S, Nakano H

    Journal of bioscience and bioengineering   Vol. 123 ( 5 ) page: 540 - 546   2017.5

     More details

    Language:English  

    DOI: 10.1016/j.jbiosc.2016.12.004

    PubMed

  20. An N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae. Reviewed

    Ojima-Kato T, Nagai S, Nakano H

    J. Biosci. Bioeng.   Vol. 123 ( 5 ) page: 540 - 546   2017.1

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2016.12.004.

  21. 'Zipbody' leucine zipper-fused Fab in E. coli in vitro and in vivo expression systems. Open Access

    Ojima-Kato T, Fukui K, Yamamoto H, Hashimura D, Miyake S, Hirakawa Y, Yamasaki T, Kojima T, Nakano H

    Protein engineering, design & selection : PEDS   Vol. 29 ( 4 ) page: 149 - 57   2016.4

     More details

    Language:English  

    DOI: 10.1093/protein/gzw001

    PubMed

  22. Development of a novel immunosorbent homogeneous assay system using luciferase-antibody complex and dye for luminescence absorption Reviewed

    Mori Akihiro, Ojima-Kato Teruyo, Fuchi Shingo, Kojima Takaaki, Nakano Hideo

    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   Vol. 251   2016.3

     More details

  23. Matrix-assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Can Precisely Discriminate the Lineages of Listeria monocytogenes and Species of Listeria. Open Access

    Ojima-Kato T, Yamamoto N, Takahashi H, Tamura H

    PloS one   Vol. 11 ( 7 ) page: e0159730   2016

     More details

  24. Supplemental epilactose prevents metabolic disorders through uncoupling protein-1 induction in the skeletal muscle of mice fed high-fat diets. Open Access

    Murakami Y, Ojima-Kato T, Saburi W, Mori H, Matsui H, Tanabe S, Suzuki T

    The British journal of nutrition   Vol. 114 ( 11 ) page: 1774 - 83   2015.12

     More details

    Language:English  

    DOI: 10.1017/S0007114515003505

    PubMed

  25. In vitro generation of rabbit anti-Listeria monocytogenes monoclonal antibody using single cell based RT-PCR linked cell-free expression systems.

    Ojima-Kato T, Hashimura D, Kojima T, Minabe S, Nakano H

    Journal of immunological methods   Vol. 427   page: 58 - 65   2015.12

     More details

    Language:English  

    DOI: 10.1016/j.jim.2015.10.001

    PubMed

  26. Assessing the performance of novel software Strain Solution on automated discrimination of Escherichia coli serotypes and their mixtures using matrix-assisted laser desorption ionization-time of flight mass spectrometry. Open Access

    Ojima-Kato T, Yamamoto N, Iijima Y, Tamura H

    Journal of microbiological methods   Vol. 119   page: 233 - 8   2015.12

     More details

  27. Structural analysis of the α-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism.

    Shen X, Saburi W, Gai Z, Kato K, Ojima-Kato T, Yu J, Komoda K, Kido Y, Matsui H, Mori H, Yao M

    Acta crystallographica. Section D, Biological crystallography   Vol. 71 ( Pt 6 ) page: 1382 - 91   2015.6

     More details

    Language:English  

    DOI: 10.1107/S139900471500721X

    PubMed

  28. Crystallization and preliminary X-ray crystallographic analysis of α-glucosidase HaG from Halomonas sp. strain H11. Open Access

    Shen X, Saburi W, Gai ZQ, Komoda K, Yu J, Ojima-Kato T, Kido Y, Matsui H, Mori H, Yao M

    Acta crystallographica. Section F, Structural biology communications   Vol. 70 ( Pt 4 ) page: 464 - 6   2014.4

     More details

    Language:English  

    DOI: 10.1107/S2053230X14001940

    PubMed

  29. Discrimination of Escherichia coli O157, O26 and O111 from other serovars by MALDI-TOF MS based on the S10-GERMS method. Open Access

    Ojima-Kato T, Yamamoto N, Suzuki M, Fukunaga T, Tamura H

    PloS one   Vol. 9 ( 11 ) page: e113458   2014

     More details

  30. Identification and characterization of cellobiose 2-epimerase from various aerobes. Reviewed

    Ojima, T., Saburi, W.*, Yamamoto, T., Mori, H. and Matsui, H.

    Biosci. Biotechnol. Biochem   Vol. 77   page: 189 - 193   2013

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  31. Immobilization of a thermostable cellobiose 2-epimerase from Rhodothermus marinus JCM9785 and continuous production of epilactose. Reviewed

    Sato, H., Saburi, W.*, Ojima, T., Taguchi, H., Mori, H. and Matsui, H.

    Biosci. Biotechnol. Biochem   Vol. 76   page: 1584 - 1587   2012

  32. α-Glucosylated 6-gingerol: chemoenzymatic synthesis using α-glucosidase from Halomonas sp. H11, and its physical properties Reviewed

    Ojima, T.*, Aizawa, K., Saburi, W. and Yamamoto, T.

    Carbohydr. Res.   Vol. 354   page: 59 - 64   2012

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  33. Characterization of Halomonas sp. H11 α-glucosidase activated by monovalent cations and its application for efficient synthesis of α-D-glucosylglycerol Reviewed

    Ojima, T.*, Saburi, W., Yamamoto, T. and Kudo, T.

    Appl. Environ. Microbiol.   Vol. 78   page: 1836 - 1845   2012

     More details

    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  34. Biochemical characterization of a thermophilic cellobiose 2-epimerase from a thermohalophilic bacterium, Rhodothermus marinus JCM9785 Reviewed

    Ojima, T., Saburi, W.*, Sato, H., Yamamoto, T., Mori, H. and Matsui, H.

    Bioscience, Biotechnology, and Biochemistry   Vol. 75   page: 2162 - 2168   2011

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

  35. Emulsion Culture: A Miniaturized Library Screening System Based on Micro-droplets in an Emulsified Medium Reviewed

    Kojima,T., Nagao, N., Ando, D., Ojima, T., Kawarasaki, Y., Kobayashi, I., Nakajima, M., and Nakano, H

    J. Biosci. Bioeng   Vol. 112   page: 299 - 303   2011

     More details

    Publishing type:Research paper (scientific journal)  

  36. Quantitative Y2H screening: Cloning and signal peptide engineering of a fungal secretory LacA gene and its application to yeast two-hybrid system as a quantitative reporter

    Kamiya Takuma, Ojima Teruyo, Sugimoto Kanoko, Nakano Hideo, Kawarasaki Yasuaki

    JOURNAL OF BIOTECHNOLOGY   Vol. 146 ( 4 ) page: 151 - 159   2010.4

     More details

  37. 3Fa14 Semi-quantitative Y2H screening system based on fungal secretory galactosidase Open Access

    Kamiya Takuma, Ojima Teruyo, Sugimoto Kanoko, Ikeuchi Akinori, Iwasaki Yugo, Nakano Hideo, Kawarasaki Yasuaki

      Vol. 20   page: 169   2008

     More details

    Language:Japanese  

    Open Access

    CiNii Research

▼display all

Books 1

  1. Studies on enzymatic synthesis of functional sugars

    小島 晃代

    [s.n.]  2013 

     More details

    Language:English

    CiNii Research

MISC 2

  1. 大腸菌におけるタンパク質生産改善のための技術開発 Invited Reviewed

    加藤晃代

    酵素工学ニュース   ( 94 ) page: 5 - 9   2025

     More details

    Authorship:Lead author, Last author, Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  2. 3P-012 Cell-free protein synthesis of Leucine Zipper-fused Fab

    Fukui Kansuke, Yamamoto Hiroaki, Hashimura Dai, Kato Teruyo, Kojima Takaaki, Nakano Hideo

      Vol. 66   page: 197 - 197   2014

     More details

Presentations 94

  1. アミノ酸配列に着目した翻訳されやすいタンパク質の設計技術開発 Invited

    加藤晃代、横山源太朗、本野千恵、西河佑馬、中野秀雄、浜田道昭

    第3回MfIP連携探索WS  2025.3.14  マス・フォア・インダストリ・プラットフォーム (MfIP)

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  2. 翻訳促進ペプチドタグに対するウサギモノクローナル抗体の取得

    山内香奈、木原もなみ、加藤晃代、中野秀雄

    化学工学会第90年会  2025.3.12 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  3. 狂犬病ウイルスモノクローナル抗体探索

    中島琉葵、木原もなみ、加藤晃代、中野秀雄

    化学工学会第90年会  2025.3.12 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

  4. 狂犬病ウイルスに対するヒト・ウサギモノクローナル抗体の取得と医学獣医学応用

    中島琉葵、木原もなみ、加藤晃代、中野秀雄

    第2回COMITシンポジウム  2025.3.7 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  5. 短いペプチドによる翻訳促進現象とタンパク質生産性向上に向けた応用展開

    加藤 晃代

    日本農芸化学会2025年度札幌大会  2025.3.6 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:札幌  

  6. 翻訳促進ペプチドによる翻訳アレスト解除とその速度論的解析

    西河佑馬, 加藤晃代, 中野秀雄

    日本農芸化学会2025年度札幌大会  2025.3.6 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  7. 真核系無細胞タンパク質合成系を用いた翻訳促進新生鎖の探索

    高井陸杜、加藤晃代 、中野秀雄

    日本農芸化学会2025年度札幌大会  2025.3.6 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  8. cDNAディスプレイ技術による大腸菌翻訳促進ペプチドの探索

    下地理子、藤川璃子、中野秀雄、加藤晃代

    日本農芸化学会2025年度札幌大会  2025.3.6 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  9. 翻訳促進ペプチドと大腸菌発現系によるヒト由来酵素の生産量向上検討

    内山さくら、安藤知佳、恒松雄太、中野秀雄、加藤晃代

    日本農芸化学会2025年度札幌大会  2025.3.6 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  10. 出芽酵母における翻訳促進新生鎖の探索と応用

    岡田航輝、間部悟司、加藤晃代、朱博、北口哲也、中野秀雄

    日本農芸化学会2025年度札幌大会  2025.3.6 

     More details

    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  11. ペプチドによる翻訳促進とタンパク質生産増大に関する研究 Invited

    加藤 晃代

    大隅基礎科学創成財団微生物コンソーシアム定例会  2025.1.31  大隅基礎科学創成財団

     More details

    Event date: 2025.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン  

  12. Microbial application for the industry and efficient production of recombinant proteins Invited International conference

    Teruyo KATO

    2024 Sakura-Bio Meeting  2024.12.16 

     More details

    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Onna (Okinawa)   Country:Japan  

  13. Development of monoclonal antibody targeting membrane protein utilizing in vitro system

    Daffa Sean ADINEGORO, Teruyo KATO, Hideo NAKANO

    2024 Sakura-Bio Meeting  2024.12.16 

     More details

    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Venue:Onna (Okinawa)   Country:Japan  

  14. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo KATO

    2024 Sakura-Bio Meeting  2024.12.17 

     More details

    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Onna (Okinawa)   Country:Japan  

  15. Analysis of intestinal bacteria-binding monoclonal antibodies derived from rabbit single B cells using the Brevibacillus choshinensis expression system International conference

    Khairil ANWAR, Daffa Sean ADINEGORO, Monami KIHARA, Teruyo OJIMA-KATO, Hideo NAKANO

    2024 Sakura-Bio Meeting  2024.12 

     More details

    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (general)  

  16. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    24th AAACU Biennial Conference and General Assembly  2024.12 

     More details

    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  17. 博士の様々な選択肢の一例 Invited

    加藤 晃代

    生命系卓越大学院共創シンポジウム  2024.11.14 

     More details

    Event date: 2024.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋  

  18. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    2024.11 

     More details

    Event date: 2024.11

    Language:Japanese   Presentation type:Poster presentation  

  19. 再構成系無細胞タンパク質合成系を利用した抗体機能評価とエンジニアリング Invited

    加藤 晃代, 中野 秀雄

    第47回日本分子生物学会年会シンポジウム「アカデミア創薬」  2024.11 

     More details

    Event date: 2024.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡  

  20. cDNAディスプレイ法による翻訳促進新生ペプチドの探索

    藤川 璃子, 下地 理子, 中野 秀雄, 加藤 晃代

    第4回天野エンザイム酵素研究助成報告会  2024.11 

     More details

    Event date: 2024.11

    Language:Japanese   Presentation type:Poster presentation  

  21. タンパク質生産量増大に向けた翻訳促進ペプチドの利用検討

    岡田 杏梨, 加藤 晃代, 佐分利 亘, 中野 秀雄

    第4回天野エンザイム酵素研究助成報告会  2024.11 

     More details

    Event date: 2024.11

    Venue:名古屋  

  22. 出芽酵母における翻訳促進新生鎖の探索

    岡田 航輝, 間部 悟司, 加藤 晃代, 朱 博, 北口 哲也, 中野 秀雄

    第4回天野エンザイム酵素研究助成報告会  2024.11 

     More details

    Event date: 2024.11

    Language:Japanese   Presentation type:Poster presentation  

  23. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis

    2024.10 

     More details

    Event date: 2024.11

  24. Enhanced Production of Phospholipase D from Streptomyces antibioticus in Escherichia coli Cytoplasmic Expression System using Translation Enhancing Peptides

    Lalu UNSUNNIDHAL, Teruyo OJIMA-KATO, Jasmina DAMNJANOVIC, Hideo NAKANO

    2024.11 

     More details

    Event date: 2024.11

    Language:English   Presentation type:Poster presentation  

  25. 翻訳促進ペプチドタグを用いた酵素の低生産性解消技術の開発

    加藤 晃代

    第4回天野エンザイム酵素研究助成報告会  2024.11 

     More details

    Event date: 2024.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋  

  26. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    29th Symposium of Young Asian Biological Engineers' Community  2024.10 

     More details

    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Country:Korea, Republic of  

  27. 翻訳効率の改変技術開発 Invited

    加藤 晃代

    第37回日本微生物生態学会  2024.10 

     More details

    Event date: 2024.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:広島  

  28. 翻訳促進ペプチドの開発とタンパク質機能解析への応用 Invited

    加藤 晃代

    第74回日本放線菌学会学術講演会  2024.10 

     More details

    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:東京  

  29. Antibody screening and engineering technology using cell-free protein synthesis Invited International conference

    Teruyo OJIMA-KATO, Hideo NAKANO

    29th Symposium of Young Asian Biological Engineers' Community  2024.10 

     More details

    Event date: 2024.10

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Pusan   Country:Korea, Republic of  

  30. Obtaining human monoclonal antibodies against intestinal bacteria

    Monami KIHARA, Teruyo OJIMA-KATO, Sayaka KONDO, Yukine YOKOO, Hideo NAKANO

    29th Symposium of Young Asian Biological Engineers' Community  2024.10 

     More details

    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Venue:Pusan   Country:Korea, Republic of  

  31. リボソームディスプレイによる抗腸内細菌 ヒトモノクローナル抗体取得法の開発

    木原 もなみ, 横尾 幸音, 近藤 冴香, 加藤 晃代, 中野 秀雄

    第76回日本生物工学会  2024.9  日本生物工学会

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  32. cDNAディスプレイ法による翻訳促進新生ペプチドの探索

    藤川 璃子, 下地 理子, 中野 秀雄, 加藤 晃代

    日本農芸化学会中部支部第199回例会  2024.9 

     More details

    Event date: 2024.9

    Venue:名古屋  

  33. リボソームディスプレイと微生物分泌発現系を用いた抗PAタグ抗体の親和性成熟技術の開発

    岡田 杏梨, 木原 もなみ, 奥田 理央, 加藤 晃代, 中野 秀雄

    日本農芸化学会中部支部第199回例会  2024.9 

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  34. 抗狂犬病ウイルスモノクローナル抗体探索

    中島 琉葵, 中野 秀雄, 加藤 晃代, 木原 もなみ

    日本農芸化学会中部支部第199回例会  2024.9 

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

  35. 出芽酵母における翻訳促進新生鎖の探索

    岡田 航輝, 間部 悟司, 加藤 晃代, 朱 博, 北口 哲也, 中野 秀雄

    日本農芸化学会中部支部第199回例会  2024.9 

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

  36. SKIKペプチドタグに対するウサギモノクロ―ナル抗体の取得

    山内 香奈, 木原 もなみ, 加藤 晃代, 中野 秀雄

    日本農芸化学会中部支部第199回例会  2024.9 

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  37. 微生物由来トランスグルタミナーゼの基質プロファイリングとその優先配列の探索

    大庭 侑起, Jasmina DAMNJANOVIC, 中野 秀雄, 加藤 晃代, 人見 清隆, T. I. Kalhari MUNAWEERA

    第76回日本生物工学会  2024.9  日本生物工学会

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  38. 翻訳促進新生ペプチドを用いた連続プロリンを有するタンパク質の生産性向上技術の開発

    藤川 璃子, 中野 秀雄, 加藤 晃代

    第76回日本生物工学会  2024.9  日本生物工学会

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  39. リボソームディスプレイと微生物分泌発現系を用いた抗PAタグ抗体の親和性成熟技術の開発

    岡田 杏梨, 中野 秀雄, 加藤 晃代, 木原 もなみ, 奥田 理央

    第76回日本生物工学会  2024.9  日本生物工学会

     More details

    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  40. 大腸菌による Fab 抗体の生産と自動リフォールディング技術の開発

    Hoang Anh Tung, 加藤 晃代, 中野 秀雄

    2024年度日本生物工学会中部支部例会・中部支部30周年記念講演会  2024.8 

     More details

    Event date: 2024.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋  

  41. Development of a method for collecting monoclonal antibodies against intestinal bacteria International conference

    Monami KIHARA, Teruyo KATO, Sayaka KONDO, Yukine YOKOO, Hideo NAKANO

    Glyco-core Symposium 2024  2024.7 

     More details

    Event date: 2024.7

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  42. 翻訳促進ペプチドによるタンパク質生産効率化 Invited

    加藤 晃代

    第24回日本蛋白質科学会年会ワークショップ  2024.6 

     More details

    Event date: 2024.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:札幌  

  43. 翻訳促進ペプチドによる翻訳アレスト解除とその速度論的解析

    西河 佑馬, 加藤 晃代, 中野 秀雄

    第24回日本蛋白質科学会年会  2024.6  日本蛋白質科学会

     More details

    Event date: 2024.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  44. Research on Translation Enhancing nascent Peptides Invited International conference

    Teruyo KATO

    2024.5 

     More details

    Event date: 2024.5

    Language:English   Presentation type:Poster presentation  

    Venue:Strasburg   Country:France  

  45. Expression of Intestinal Bacteria-binding Monoclonal Antibodies Derived from Rabbit Single B Cells Using Brevibacillus choshinensis

    2023.10 

     More details

    Presentation type:Oral presentation (general)  

  46. Improving Production and Characterizing Properties of Difficult-to-Express Proteins in E. coli

    Anri OKADA, Masanori UCHIYAMA, Wataru SABURI, Hideo NAKANO, Teruyo OJIMA-KATO

    第5回天野エンザイム酵素研究助成報告会  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  47. creening of novel translation-enhancing peptides to improve recombinant protein productivity in Bacillus subtilis

    Khairil ANWAR, Hideo NAKANO, and Teruyo OJIMA-KATO

    第5回天野エンザイム酵素研究助成報告会  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  48. 大腸菌における翻訳促進ペプチドの機械学習による予測と実証

    本野 千恵、横山 源太朗、中野 秀雄、加藤 晃代、浜田 道昭

    日本生物物理学会  2025.9 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:奈良  

  49. 大腸菌における難生産異種タンパク質の生産改善と性質決定

    岡田 杏梨, 内山 昌典, 佐分利 亘, 中野 秀雄, 加藤 晃代

    日本農芸化学会中部支部 第202回支部例会  2025.9 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  50. 腸内細菌に対するヒトモノクローナル抗体取得と大量合成に関する研究

    横尾 幸音, 木原 もなみ, 加藤 晃代, 中野 秀雄

    日本農芸化学会中部支部 第202回支部例会  2025.9 

     More details

    Language:Japanese   Presentation type:Poster presentation  

  51. D-アスパラギン酸認識ウサギモノクローナル抗体の探索

    大橋 侑里子, 木原 もなみ, 加藤 晃代, 中野 秀雄

    日本農芸化学会中部支部 第202回支部例会  2025.9 

     More details

    Presentation type:Poster presentation  

  52. ヒト由来酵素に対する翻訳促進ペプチドの応用

    内山 さくら, 安藤 知佳, 恒松 雄太, 中野 秀雄, 加藤 晃代

    日本農芸化学会中部支部 第202回支部例会  2025.9 

     More details

    Presentation type:Poster presentation  

    Venue:名古屋  

  53. SKIKタグによる翻訳促進現象の速度論的解析とその応用

    吉野 明道, 西河 佑馬, 中野 秀雄, 加藤 晃代

    日本農芸化学会中部支部 第202回支部例会  2025.9 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  54. SKIKペプチドによる翻訳促進機構解明に関する研究

    西河 佑馬, 中野 秀雄, 加藤 晃代

    日本農芸化学会中部支部 第202回支部例会  2025.9  日本農芸化学会中部支部

     More details

    Presentation type:Poster presentation  

    Venue:名古屋  

  55. 機械学習と実験によるタンパク質の翻訳促進配列の探索と検証

    本野 千恵, 横山 源太朗, 中野 秀雄, 浜田 道昭, 加藤 晃代

    2025年日本バイオインフォマティクス学会年会ワークショップ「BIが駆動するバイオものづくり」  2025.9 

     More details

    Presentation type:Poster presentation  

    Venue:名古屋  

  56. SKIKによる翻訳促進現象の速度論的解析

    吉野 明道, 西河 佑馬, 中野 秀雄, 加藤 晃代

    生物工学若手研究者の集い(若手会)夏のセミナー2025 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:福岡  

  57. 連続プロリン配列が引き起こす翻訳停止に対する翻訳促進SKIKタグの影響

    西河 佑馬, 中野 秀雄, 加藤 晃代

    生物工学若手研究者の集い(若手会)夏のセミナー2025  2025.7 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:福岡  

  58. 機械学習を用いた翻訳を促進するアミノ酸配列の探索と実測結果を採り入れた精度改善のループ構築

    横山 源太朗, 本野 千恵, 加藤 晃代, 中野 秀雄, 浜田 道昭

    GteXバイオものづくり領域 若手研究者交流会  2025.5 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:淡路  

  59. 翻訳促進ペプチド(TEP)とアレストペプチドとの距離が及ぼすアレスト緩和効果への影響

    西河 佑馬, 中野 英雄, 加藤 晃代

    GteXバイオものづくり領域 若手研究者交流会  2025.5 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:淡路  

  60. アミノ酸配列に着目した翻訳されやすいタンパク質の設計技術開発

    加藤 晃代, 横山 源太朗, 本野 千恵, 西河 佑馬, 中野 秀雄, 浜田道昭

    GX実現に向けた異分野連携シンポジウム(中部地区)  2025.4 

     More details

    Language:Japanese   Presentation type:Poster presentation  

  61. 転写-翻訳共役系におけるDNA直接投入型リボソームディスプレイ法の開発

    津田 晃輝、加藤 晃代、中野 秀雄

    日本農芸化学会2026年度京都大会  2026.3  日本農芸化学会

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都  

  62. Effect of Translation-Enhancing Peptide to Improve recombinant protein productivity in Bacillus subtilis

    Khairil ANWAR Hideo NAKANO, and Teruyo OJIMA-KATO

    日本農芸化学会2026年度京都大会  2026.3  日本農芸化学会

     More details

    Language:English   Presentation type:Oral presentation (general)  

    Venue:京都  

  63. cDNA display技術による翻訳促進ペプチドの探索~小麦胚芽無細胞系への応用~

    藤川 璃子、中野 秀雄、加藤 晃代

    日本農芸化学会2026年度京都大会  2026.3  日本農芸化学会

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都  

  64. 大腸菌における難生産異種タンパク質の生産改善と性質決定

    岡田 杏梨、内山 昌典、佐分利 亘、中野 秀雄、加藤 晃代

    日本農芸化学会2026年度京都大会  2026.3  日本農芸化学会

     More details

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:京都  

  65. 翻訳アレストに対する翻訳促進ペプチドの影響

    西河 佑馬, 吉野 明道, 中野 秀雄, 加藤 晃代

    第77回日本生物工学会  2025.9  日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

    Venue:広島  

  66. Analysis of Intestinal Bacteria-binding Monoclonal Antibodies (mAbs) Derived from Rabbit Single B Cells

    Khairil Anwar, Daffa Sean Adinegoro, Monami Kihara, Teruyo Ojima-Kato, and Hideo Nakano

    第77回日本生物工学会  2025.9  日本生物工学会

     More details

    Presentation type:Oral presentation (general)  

    Venue:広島  

  67. タンパク質発現向上のための翻訳促進ペプチドの機械学習と実験による探索

    本野 千恵, 横山 源太朗, 中野 秀雄, 浜田 道昭, 加藤 晃代

    2025年日本バイオインフォマティクス学会年会ワークショップ「BIが駆動するバイオものづくり」  2025.9 

     More details

    Presentation type:Symposium, workshop panel (public)  

    Venue:名古屋  

  68. 翻訳促進ペプチドによる、難生産タンパク質の生産実現― 抗体医薬、バイオプラスチック、バイオ燃料への応用展開 ―

    加藤 晃代

    第19回Seeds-Hubミニセミナー  2025.12 

     More details

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:オンライン  

  69. ペプチドによる翻訳促進

    加藤 晃代

    タタバイオ分子クラブ  2025.11 

     More details

    Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  70. 翻訳促進技術の開発とバイオものづくりへの応用展開 Invited

    加藤 晃代

    第2回OEB×GteX連携イベント  2025.10  OEB科学・素材・燃料分科会

     More details

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:昭島  

  71. 大腸菌発現系を用いたタンパク質生産の効率化 Invited

    加藤 晃代

    第25回日本蛋白質科学会年会WS  2025.6 

     More details

    Presentation type:Symposium, workshop panel (public)  

    Venue:姫路  

  72. 翻訳効率を向上させるペプチド配列の開発と利用 Invited

    加藤 晃代

    遺伝研研究会  2025.10 

     More details

    Venue:三島  

  73. 蛋白質異種発現の効率を増加させる秘訣 Invited

    加藤 晃代

    第65回澱粉研究懇談会  2025.6 

     More details

    Language:Japanese  

    Venue:伊東  

  74. Proteotyping of Foodborne causing Bacteria by MALDI-TOF MS and Strain Solution Version 2 Software Invited

    6th Europian Public Health Conference  2023.10 

     More details

    Presentation type:Oral presentation (invited, special)  

  75. Newly generated nascent chain accelerating translation

    EMBL Conference: Protein synthesis and translational control  2023.9 

     More details

    Presentation type:Poster presentation  

  76. Production of Fab antibodies in Escherichia coli and development of automated refolding process

    Tung Anh HOANG, Hideo NAKANO, Teruyo OJIMA-KATO

    第5回天野エンザイム酵素研究助成報告会  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  77. Development and Application of Translation Enhancing Peptides in Escherichia coli International conference

    Teruyo OJIMA-KATO, Gentaro YOKOYAMA, Hideo NAKANO, Chie MOTONO, Michiaki HAMADA

    Pacifichem 2025  2025.12 

     More details

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Honolulu   Country:United States  

  78. Exploration and application of translation-enhancing peptides in Saccharomyces cerevisiae International conference

    Sakura UCHIYAMA, Koki OKADA, Bo ZHU, Tetsuya KITAGUCHI, Hideo NAKANO, Teruyo OJIMA-KATO

    International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Onna   Country:Japan  

  79. Kinetic analysis and application of the SKIK peptide for improved production of polyproline-containing proteins International conference

    Akimichi YOSHINO, Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    International Conference on Bottom-up Biotechnoolgy for Understanding and Engineering Living Sytems 2025  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Onna   Country:Japan  

  80. Study on the Mechanism of Translation Enhancement by the SKIK Peptide International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Onna   Country:Japan  

  81. Screening of translation-enhancing peptides (TEPs) in a mammalian expression system International conference

    Yuma NISHIKAWA, Rikuto TAKAI, Hideo NAKANO, Teruyo OJIMA-KATO

    30 th Symposium of Young Asian Biological Engineers’ community (YABEC2025)  2025.11  Young Asian Biological Engineers’ community

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Matsue   Country:Japan  

  82. Kinetic analysis of translation enhancement by the SKIK tag and its application

    Akimichi YOSHINO, Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    30 th Symposium of Young Asian Biological Engineers’ community (YABEC2025)  2025.11 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Matsue   Country:Japan  

  83. Analysis of Intestinal Bacteria-binding Monoclonal Antibodies Derived from Rabbit Single B Cells International conference

    Khairil Anwar, Teruyo Ojima-Kato, Hideo Nakano

    KMB2025 52nd Annual Meeting & International Symposium  2025.6 

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Busan   Country:Korea, Republic of  

  84. Strategy for Efficient Protein Production using Translation-Enhancing Peptides in Escherichia coli International conference

    Teruyo OJIMA-KATO, Gentaro YOKOYAMA, Hideo NAKANO, Chie MOTONO, Michiaki HAMADA

    KSBB-AFOB Conference 2025  2025.9  AFOB

     More details

    Language:English   Presentation type:Poster presentation  

    Venue:Incheon   Country:Korea, Republic of  

  85. Development of translation-enhancing peptides in Escherichia coli Invited International conference

    Teruyo OJIMA-KATO

    30 th Symposium of Young Asian Biological Engineers’ community (YABEC2025)  2025.11  Young Asian Biological Engineers’ community

     More details

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Matsue   Country:Japan  

  86. Translation-Enhancing Peptides and their Application for Synthetic Biology International conference

    Teruyo OJIMA-KATO

    2025 Annual Conference of Asian Synthetic Biology Association  2025.12  Asian Synthetic Biology Association

     More details

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Jeju   Country:Korea, Republic of  

  87. Development of Translation Enhancing Peptides and their Applications for Improved Protein Production

    Teruyo OJIMA-KATO, Yuma NISHIKAWA, Riko FUJIKAWA, Hideo NAKANO, Gentaro YOKOYAMA, Chie MOTONO, Michiaki HAMADA

    International Conference on Bottom-up Biotechnology for Understanding and Engineering Living Systems 2025  2025.11 

     More details

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Onna   Country:Japan  

  88. Development and Application of Translation Enhancing Peptides International conference

    Teruyo Ojima-Kato

    KMB2025 52nd Annual Meeting & International Symposium  2025.6 

     More details

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Busan   Country:Korea, Republic of  

  89. 翻訳されやすいタンパク質の設計技術開発

    加藤晃代

    第77回日本生物工学会シンポジウム「バイオものづくり社会実装に向けた異分野融合研究の最前線」  2025.9 

     More details

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:広島  

  90. 翻訳促進ペプチド導入による連続プロリンを含むタンパク質の翻訳効率向上

    西河 佑馬、吉野 明道、中野 秀雄、加藤 晃代

    GteXバイオものづくり領域第4回全体会議  2026.3 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

  91. 大腸菌における翻訳促進ペプチドの開発とその応用

    加藤 晃代、横山 源太朗、中野 秀雄、本野 千恵、浜田 道昭

    GteXバイオものづくり領域第4回全体会議  2026.3 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸  

  92. 大腸菌による Fab 抗体の生産と自動リフォールディング技術の開発

    Tung Anh HOANG, 中野 秀雄, 加藤 晃代

    2025 パンシンポジウム×第 11 回 CHUBU 懇話会  2025.11 

     More details

    Presentation type:Poster presentation  

  93. 腸内細菌に対するヒトモノクローナル抗体取得と大量合成

    横尾 幸音、木原もなみ、加藤 晃代、中野 秀雄

    第4回日本抗体学会学術大会  2025.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大宮  

  94. D-アスパラギン酸認識ウサギモノクローナル抗体の探索

    大橋 侑里子、木原 もなみ、加藤 晃代、中野 秀雄

    第4回日本抗体学会学術大会  2025.12 

     More details

    Language:Japanese   Presentation type:Poster presentation  

    Venue:大宮  

▼display all

Research Project for Joint Research, Competitive Funding, etc. 6

  1. バイオプロダクションの生産性超効率化に向けた基盤技術開発

    2025.10

    産総研ー名古屋大学アライアンス事業(大型) 

    加藤晃代、本野千恵、中野秀雄

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3000000 ( Direct Cost: \3000000 )

  2. 酵母と枯草菌における翻訳促進ペプチドタグの探索・応用研究

    Grant number:20251244  2025.4 - 2026.3

    基盤共同研究

    加藤晃代、朱博、中野秀雄、北口哲也

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\145000 ( Direct Cost: \145000 )

  3. 翻訳されやすいタンパク質の設計技術開発

    2023.10 - 2024.3

    革新的GX技術創出事業(GteX)バイオものづくり  革新的要素技術研究

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\13000000 ( Direct Cost: \100000000 、 Indirect Cost:\3000000 )

  4. 翻訳制御機構の解明とバイオ産業への応用

    Grant number:JPMJFR2204  2023.4

    創発的研究支援事業   創発的研究支援事業

      More details

    Authorship:Principal investigator  Grant type:Competitive

  5. 翻訳促進新生鎖の網羅的探索とルール解明

    Grant number:23K04989  2023.4 - 2026.3

    科学研究費助成事業   基盤研究(C)

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\46800000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

  6. 翻訳されやすいタンパク質のデザインに向けた研究

    2022.10 - 2024.3

    産総研ー名古屋大学アライアンス事業 

    加藤晃代、本野千恵、中野秀雄

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1200000 ( Direct Cost: \1200000 )

▼display all

KAKENHI (Grants-in-Aid for Scientific Research) 7

  1. 翻訳されやすいタンパク質の設計技術開発

    2023.10 - 2024.3

    国立研究開発法人科学技術振興機構  革新的GX技術創出事業(GteX)  革新的要素技術研究

    加藤晃代、中野秀雄、本野千恵、浜田道昭、横山源太朗

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\13000000 ( Direct Cost: \10000000 、 Indirect Cost:\3000000 )

  2. 翻訳制御機構の解明とバイオ産業への応用

    Grant number:JPMJFR2204  2023.4

    国立研究開発法人科学技術振興機構  創発的研究支援事業   創発的研究支援事業

      More details

    Authorship:Principal investigator  Grant type:Competitive

  3. 新生鎖による翻訳促進機構に関する研究

    Grant number:20K05806  2020.4 - 2023.3

    日本学術振興会  科学研究費助成事業   基盤研究(C)

      More details

    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

  4. タンパク質発現可能化ルールの解明

    Grant number:18K19187  2018.6 - 2020.3

    日本学術振興会  科学研究費助成事業   挑戦的研究(萌芽)

    田村廣人

      More details

    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\6370000 ( Direct Cost: \4900000 、 Indirect Cost:\1470000 )

  5. 難発現タンパク質の生産可能化技術構築

    Grant number:18K14392  2018.4 - 2020.3

    日本学術振興会  科学研究費助成事業   若手研究

      More details

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

  6. 転写翻訳速度制御因子の探索と制御機構の解明

    2017.4 - 2018.3

    特別研究員奨励費

      More details

    Authorship:Principal investigator  Grant type:Competitive

  7. Development of a nanostructured hybrid antibody molecule with DNA scaffold

    Grant number:26820360  2014.4 - 2016.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    Kato Teruyo

      More details

    Authorship:Principal investigator 

    Grant amount:\4030000 ( Direct Cost: \3100000 、 Indirect Cost:\930000 )

    Antibodies have become essential tool in the life technology fields and their applications as a high-sensitivity sensor are increasing.
    In this research, we have developed a novel sensor molecule named ‘Hybribody’ which consists of DNA (PCR product or plasmid), DNA-binding protein, and antibody (scFv). First, we established an efficient production scheme for fusion proteins of DNA-binding protein and scFv using E. coli expression systems with an N-teminal tag and chaperon co-expression. Bivalent antibody-DNA hybrid molecule, Hybribody, was formed by mixing with the purified proteins and DNA fragments.

▼display all

Industrial property rights 14

  1. 枯草菌を用いたタグ含有タンパク質の生産方法、タグ含有タンパク質、翻訳鋳型mRNAおよび発現ベクタ

    加藤 晃代、カイリル アンワー、中野 秀雄

     More details

    Applicant:名古屋大学

    Application no:特願2026-24582  Date applied:2026.2

  2. タグ含有タンパク質、翻訳鋳型mRNA、発現ベクター、タグ含有タンパク質の生産方法

    加藤晃代、中野秀雄、本野千恵、浜田道昭、横山源太朗

     More details

    Applicant:名古屋大学、産業技術総合研究所

    Application no:特願2024-232917  Date applied:2024.12

  3. 質量分析装置、質量分析方法および質量分析プログラム

    山田 賢志、緒方 是嗣、野村 静男、田村 廣人、加藤 晃代

     More details

    Date applied:2018.7

    Patent/Registration no:7021754 

  4. 標識タンパク質を融合した抗体

    中野秀雄、森昭博、加藤晃代

     More details

    Application no:特願2016-152447  Date applied:2016.8

  5. 微生物の識別方法

    田村廣人、山本奈保美、加藤晃代、島圭介、船津慎治

     More details

    Date applied:2016.3

    Patent/Registration no:6692016 

  6. 微生物の識別方法

    田村廣人、山本奈保美、加藤晃代、島圭介、船津慎治

     More details

    Date applied:2016.3

    Patent/Registration no:6709434 

  7. 微生物の識別方法

    田村廣人、山本奈保美、加藤晃代、島圭介、船津慎治

     More details

    Date applied:2016.3

    Patent/Registration no:6864855 

  8. 免疫測定用キット及び免疫測定方法

    中野秀雄、森昭博、加藤晃代、渕真悟

     More details

    Application no:特願2015-186581  Date applied:2015.9

  9. タンパク質の発現方法

    加藤晃代、中野秀雄

     More details

    Application no:特願2015-121443  Date applied:2015.6

    Patent/Registration no:6681625 

  10. タグ付抗体

    中野秀雄、加藤晃代、兒島孝明

     More details

    Application no:特願2014-122773  Date applied:2014.6

  11. 微生物の識別方法

    田村廣人、加藤晃代、山本奈保美

     More details

    Application no:特願2014-057809  Date applied:2014.3

    Patent/Registration no:6238069 

  12. 特定菌検出法

    加藤晃代、渕真悟、中野秀雄、田村廣人、三宅司郎

     More details

    Application no:特願2013-103740  Date applied:2013.5

  13. 新規なα-グルコシダーゼとその製造法並びに用途

    小島晃代、相沢健太、和田幸樹、佐分利亘、山本健、工藤俊章

     More details

    Announcement no:特開2013-5793 

    Patent/Registration no:5933321 

  14. セロビオース2-エピメラーゼおよびその用途

    佐分利亘、小島晃代、山本健、松井博和

     More details

    Announcement no:特開2012-130332 

    Patent/Registration no:5092049 

▼display all

 

Social Contribution 4

  1. 研究、転職、起業、子育て。面白がってやってみた、の経過

    Role(s):Lecturer

    日本農芸化学会産学官若手交流会  さんわか×東北大 ミニセミナー「産官学の現場から語る研究者のリアル」  2025.7

  2. 2025年度産学官学術交流フォーラム

    Role(s):Presenter, Planner, Report writing

    日本農芸化学会産学官若手交流会  2025.3

  3. ペプチドによる翻訳促進とタンパク質生産増大に関する研究

    Role(s):Lecturer

    大隅基礎科学創成財団微生物コンソーシアム  2025.1

  4. さんわか×北大 ミニセミナー「産官学の現場から語る研究者のリアル」

    Role(s):Planner, Organizing member

    日本農芸化学会産学官若手交流会 さんわか  2024.7

Media Coverage 10

  1. 名古屋大学などの研究グループ タンパク質合成に新技術 Newspaper, magazine

    中部経済新聞  2025.11

     More details

    Author:Other 

  2. 名大など、微生物でたんぱく質を効率生産 翻訳促進ペプチド解明 Newspaper, magazine

    日刊工業新聞  2025.11

     More details

    Author:Other 

  3. AI-Engineered Peptides May Boost E. coli Protein Yields for Biomanufacturing Internet

    Genetic Engineering and Biotechnology News  https://www.genengnews.com/topics/bioprocessing/ai-engineered-peptides-may-boost-e-coli-protein-yields-for-biomanufacturing/  2025.10

  4. AI-Powered Approach Boosts Protein Production Efficiency in E. coli Internet

    AZO Life Sciences  https://www.azolifesciences.com/news/20251029/AI-Powered-Approach-Boosts-Protein-Production-Efficiency-in-E-coli.aspx  2025.10

     More details

    Author:Other 

  5. 新技术提高了大肠杆菌蛋白质生产的效率 Internet

    Mandarinian  https://www.mandarinian.news/%e6%96%b0%e6%8a%80%e6%9c%af%e6%8f%90%e9%ab%98%e4%ba%86%e5%a4%a7%e8%82%a0%e6%9d%86%e8%8f%8c%e8%9b%8b%e7%99%bd%e8%b4%a8%e7%94%9f%e4%ba%a7%e7%9a%84%e6%95%88%e7%8e%87/  2025.10

     More details

    Author:Other 

  6. Breakthrough: Efficient Protein Production from E. Coli Internet

    The MIRAGE  https://www.miragenews.com/breakthrough-efficient-protein-production-from-1558927/  2025.10

  7. Scientists develop an efficient method of producing proteins from E. coli Internet

    the microbiologist  http://ct.moreover.com/?a=58039262932&p=1pl&v=1&x=7UinJlOXLqs-cXBBzULcxA  2025.10

  8. New technology improves the efficiency of protein production in E. coli Internet

    News Medical Life Sciences  https://www.news-medical.net/news/20251028/New-technology-improves-the-efficiency-of-protein-production-in-E-coli.aspx  2025.10

     More details

    Author:Other 

  9. Nascent SKIK Peptide as a Minimal Module to Relieve Polyproline-Induced Ribosome Stalling and Enhance Translation Efficiency Internet

    Medicine Innovates  https://medicineinnovates.com/nascent-skik-peptide-minimal-module-relieve-polyproline-induced-ribosome-stalling-enhance-translation-efficiency/  2025.9

     More details

    Author:Other 

  10. Improving Protein Production: The Role of Nascent MSKIK Peptide in E. coli Internet

    Medicine Innovates  2023.12

     More details

    Author:Other 

▼display all

Academic Activities 4

  1. 2025 Annual Conference of Asian Synthetic Biology Association International contribution

    Role(s):Panel moderator, session chair, etc.

    ASBA  2025.12

     More details

    Type:Competition, symposium, etc. 

  2. YABEC2025実行委員 International contribution

    Role(s):Planning, management, etc.

    2025.4 - 2025.11

     More details

    Type:Academic society, research group, etc. 

  3. 日本農芸化学会産学官若手交流会さんわかセミナー実行委員

    Role(s):Planning, management, etc.

    2023.4

     More details

    Type:Academic society, research group, etc. 

  4. 日本生物工学会若手研究者の集いセミナー実行委員

    Role(s):Planning, management, etc.

    2023.4 - 2024.9

     More details

    Type:Academic society, research group, etc.