Updated on 2025/03/24

写真a

 
KATO Teruyo
 
Organization
Graduate School of Bioagricultural Sciences Department of Applied Biosciences Associate professor
Graduate School
Graduate School of Bioagricultural Sciences
Undergraduate School
School of Agricultural Sciences Department of Applied Biosciences
Title
Associate professor
External link

Degree 1

  1. 博士(農学) ( 2013.3   名古屋大学 ) 

Research Areas 3

  1. Life Science / Applied microbiology

  2. Life Science / Molecular biology

  3. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering  / Protein

Current Research Project and SDGs 3

  1. bio-production

  2. Microorganism

  3. Protein

Professional Memberships 3

  1. Japanese Society for Bioscience, Biotechnology, and Agrochemistry

  2. The Society for Biotechnology, Japan

  3. 日本蛋白質科学会

Awards 9

  1. 第25回酵素応用シンポジウム研究奨励賞

    2024.6   一般財団法人天野エンザイム科学技術振興財団   翻訳促進技術の開発とタンパク質生産・機能評価への応用

    加藤晃代

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    Award type:Award from publisher, newspaper, foundation, etc. 

  2. JSBBA Award for Young Scientists

    2024.3  

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    Award type:Award from Japanese society, conference, symposium, etc. 

  3. バイオインダストリー奨励賞

    2023.10   日本バイオインダストリー協会   翻訳効率を向上させるペプチドに関する研究

    加藤晃代

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    Award type:Award from publisher, newspaper, foundation, etc. 

  4. 第20回農芸化学企画賞

    2023.3   日本農芸化学会   翻訳を促進する新生ペプチドの探索とタンパク質生産への産業応用

    加藤晃代

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    Award type:Award from Japanese society, conference, symposium, etc. 

    本賞は、実学である農芸化学分野らしい優れた研究企画に対するユニークな賞です。農芸化学の特徴を活かした研究領域で、萌芽的研究および産業化を模索する比較的早期の研究の企画を対象とします。

  5. 第17回わかしゃち奨励賞応用研究部門優秀賞

    2023.1   愛知県、公益財団法人科学技術交流財団、公益財団法人日比科学技術振興財団   微生物によるマルチ機能抗体の生産技術開発

    加藤晃代

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    愛知県、(公財)科学技術交流財団及び(公財)日比科学技術振興財団が共同し、全国の優秀な若手研究者から、新たな経済価値をもたらす革新的な基礎研究や産業の高度化・発展、社会的課題の解決につながる夢のある研究テーマ・アイデアを募集し、授与するもの。

  6. 日本生物工学会技術賞

    2018.9   日本生物工学会   無細胞タンパク質合成系を利用した迅速抗体スクリーニング技術開発とその実用化

    加藤 晃代, 中野 秀雄, 兒島 孝明, 永井 里美

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    Award type:Award from Japanese society, conference, symposium, etc. 

  7. 日本生物工学会論文賞

    2018.9   日本生物工学会   N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae

    加藤晃代、永井里美、中野秀雄

  8. 日本生物工学会中部支部支部長賞

    2017.9   日本生物工学会中部支部   N 末端 SKIK ペプチドタグによるタンパク質発現増大に関する研究

    加藤晃代

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    Award type:Award from Japanese society, conference, symposium, etc. 

  9. 若手女性研究者賞

    2017.3   日本農芸化学会   有用タンパク質の微生物生産とその産業利用に関する研究

    加藤晃代

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    Award type:Award from Japanese society, conference, symposium, etc. 

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Papers 25

  1. Evaluation of antibody variants using a ribosome display and Brevibacillus choshinensis secretion system. Reviewed

    Journal of Bioscience and Bioengineering     2025.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1016/j.jbiosc.2025.02.009

  2. Effect of translation enhancing nascent SKIK peptide on the arrest peptides containing consecutive proline. Reviewed

    Nishikawa, Y., Fujikawa, R., Nakano, H., Kanamori, T. and Ojima-Kato, T.

      Vol. 13 ( 12 ) page: 3908 - 3916   2024.11

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1021/acssynbio.4c00221

  3. Glu592 of the axon guidance receptor ROBO3 mediates a pH-dependent interaction with NELL2 ligand Reviewed

    Mizutani, K., Toyoda, M., Ojima-Kato, T., Maturana, A.D. and Niimi, T.

    FEBS Letters   Vol. 599 ( 4 ) page: 571 - 580   2024.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1002/1873-3468.15054

  4. Advances in recombinant protein production in microorganisms and functional peptide tags Reviewed

    Teruyo Ojima-Kato

    Bioscience, Biotechnology, and Biochemistry   Vol. 89 ( 1 ) page: 1 - 10   2024.10

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    Authorship:Lead author, Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1093/bbb/zbae147

  5. Rapid and cost-effective epitope mapping using PURE ribosome display coupled with next-generation sequencing and bioinformatics Reviewed

      Vol. 137 ( 4 ) page: 321 - 328   2024.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2024.01.008

  6. Nascent MSKIK peptide cancels ribosomal stalling by arrest peptides in Escherichia coli Reviewed

      Vol. 299 ( 5 ) page: 104676   2023.4

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.1016/j.jbc.2023.104676

  7. Proteotyping of Campylobacter jejuni by MALDI-TOF MS and Strain Solution Version 2 Software Reviewed

    Ojima-Kato, T. , Nagai, S., Fujita, A., Sakata, J., Tamura, H.

    Microorganisms   Vol. 11 ( 1 ) page: 202   2023.1

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    Authorship:Lead author, Corresponding author   Language:English  

    DOI: https://doi.org/10.3390/microorganisms11010202

  8. Improved MALDI-MS method for the highly sensitive and reproducible detection of biomarker peaks for the proteotyping of Salmonella serotypes.

    Fukuyama Y, Ojima-Kato T, Nagai S, Shima K, Funatsu S, Yamada Y, Tamura H, Nomura S, Ogata K, Sekiya S, Iwamoto S, Tanaka K

    Journal of mass spectrometry : JMS   Vol. 54 ( 12 ) page: 966 - 975   2019.12

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    Language:English  

    DOI: 10.1002/jms.4469

    PubMed

  9. Rapid Generation of Monoclonal Antibodies from Single B Cells by Ecobody Technology

    Ojima-Kato Teruyo, Morishita Shiomi, Uchida Yoshino, Nagai Satomi, Kojima Takaaki, Nakano Hideo

    ANTIBODIES   Vol. 7 ( 4 )   2018.12

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  10. SKIK-zipbody-alkaline phosphatase, a novel antibody fusion protein expressed in Escherichia coli cytoplasm

    Ritthisan Panwad, Ojima-Kato Teruyo, Damnjanovic Jasmina, Kojima Takaaki, Nakano Hideo

    JOURNAL OF BIOSCIENCE AND BIOENGINEERING   Vol. 126 ( 6 ) page: 705 - 709   2018.12

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  11. Application of proteotyping Strain Solution™ ver. 2 software and theoretically calculated mass database in MALDI-TOF MS typing of Salmonella serotype.

    Ojima-Kato T, Yamamoto N, Nagai S, Shima K, Akiyama Y, Ota J, Tamura H

    Applied microbiology and biotechnology   Vol. 101 ( 23-24 ) page: 8557 - 8569   2017.12

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    DOI: 10.1007/s00253-017-8563-3

    PubMed

  12. Development of a rapid immunoassay system: Luminescent detection of antigen-associated antibody-luciferase in the presence of a dye that absorbs light from free antibody-luciferase.

    Mori A, Ojima-Kato T, Fuchi S, Kaiya S, Kojima T, Nakano H

    Journal of bioscience and bioengineering   Vol. 124 ( 6 ) page: 694 - 699   2017.12

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    DOI: 10.1016/j.jbiosc.2017.06.016

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  13. Ecobody technology: rapid monoclonal antibody screening method from single B cells using cell-free protein synthesis for antigen-binding fragment formation

    Ojima-Kato Teruyo, Nagai Satomi, Nakano Hideo

    SCIENTIFIC REPORTS   Vol. 7 ( 1 ) page: 13979   2017.10

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  14. N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae.

    Ojima-Kato T, Nagai S, Nakano H

    Journal of bioscience and bioengineering   Vol. 123 ( 5 ) page: 540 - 546   2017.5

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    DOI: 10.1016/j.jbiosc.2016.12.004

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  15. An N-terminal SKIK peptide tag markedly improves expression of difficult-to-express proteins in Escherichia coli and Saccharomyces cerevisiae. Reviewed

    Ojima-Kato T, Nagai S, Nakano H

    J. Biosci. Bioeng.   Vol. 123 ( 5 ) page: 540 - 546   2017.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2016.12.004.

  16. 'Zipbody' leucine zipper-fused Fab in E. coli in vitro and in vivo expression systems.

    Ojima-Kato T, Fukui K, Yamamoto H, Hashimura D, Miyake S, Hirakawa Y, Yamasaki T, Kojima T, Nakano H

    Protein engineering, design & selection : PEDS   Vol. 29 ( 4 ) page: 149 - 57   2016.4

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    Language:English  

    DOI: 10.1093/protein/gzw001

    PubMed

  17. Matrix-assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Can Precisely Discriminate the Lineages of Listeria monocytogenes and Species of Listeria.

    Ojima-Kato T, Yamamoto N, Takahashi H, Tamura H

    PloS one   Vol. 11 ( 7 ) page: e0159730   2016

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    DOI: 10.1371/journal.pone.0159730

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  18. Supplemental epilactose prevents metabolic disorders through uncoupling protein-1 induction in the skeletal muscle of mice fed high-fat diets.

    Murakami Y, Ojima-Kato T, Saburi W, Mori H, Matsui H, Tanabe S, Suzuki T

    The British journal of nutrition   Vol. 114 ( 11 ) page: 1774 - 83   2015.12

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    DOI: 10.1017/S0007114515003505

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  19. In vitro generation of rabbit anti-Listeria monocytogenes monoclonal antibody using single cell based RT-PCR linked cell-free expression systems.

    Ojima-Kato T, Hashimura D, Kojima T, Minabe S, Nakano H

    Journal of immunological methods   Vol. 427   page: 58 - 65   2015.12

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    DOI: 10.1016/j.jim.2015.10.001

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  20. Assessing the performance of novel software Strain Solution on automated discrimination of Escherichia coli serotypes and their mixtures using matrix-assisted laser desorption ionization-time of flight mass spectrometry.

    Ojima-Kato T, Yamamoto N, Iijima Y, Tamura H

    Journal of microbiological methods   Vol. 119   page: 233 - 8   2015.12

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    DOI: 10.1016/j.mimet.2015.11.005

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  21. Structural analysis of the α-glucosidase HaG provides new insights into substrate specificity and catalytic mechanism.

    Shen X, Saburi W, Gai Z, Kato K, Ojima-Kato T, Yu J, Komoda K, Kido Y, Matsui H, Mori H, Yao M

    Acta crystallographica. Section D, Biological crystallography   Vol. 71 ( Pt 6 ) page: 1382 - 91   2015.6

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    DOI: 10.1107/S139900471500721X

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  22. Crystallization and preliminary X-ray crystallographic analysis of α-glucosidase HaG from Halomonas sp. strain H11.

    Shen X, Saburi W, Gai ZQ, Komoda K, Yu J, Ojima-Kato T, Kido Y, Matsui H, Mori H, Yao M

    Acta crystallographica. Section F, Structural biology communications   Vol. 70 ( Pt 4 ) page: 464 - 6   2014.4

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    DOI: 10.1107/S2053230X14001940

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  23. Discrimination of Escherichia coli O157, O26 and O111 from other serovars by MALDI-TOF MS based on the S10-GERMS method.

    Ojima-Kato T, Yamamoto N, Suzuki M, Fukunaga T, Tamura H

    PloS one   Vol. 9 ( 11 ) page: e113458   2014

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    DOI: 10.1371/journal.pone.0113458

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  24. Quantitative Y2H screening: Cloning and signal peptide engineering of a fungal secretory LacA gene and its application to yeast two-hybrid system as a quantitative reporter

    Kamiya Takuma, Ojima Teruyo, Sugimoto Kanoko, Nakano Hideo, Kawarasaki Yasuaki

    JOURNAL OF BIOTECHNOLOGY   Vol. 146 ( 4 ) page: 151 - 159   2010.4

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  25. 3Fa14 Semi-quantitative Y2H screening system based on fungal secretory galactosidase

    Kamiya Takuma, Ojima Teruyo, Sugimoto Kanoko, Ikeuchi Akinori, Iwasaki Yugo, Nakano Hideo, Kawarasaki Yasuaki

      Vol. 20   page: 169   2008

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    Language:Japanese  

    CiNii Research

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Books 1

  1. Studies on enzymatic synthesis of functional sugars

    小島 晃代

    [s.n.]  2013 

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    Language:English

    CiNii Books

MISC 1

  1. 3P-012 Cell-free protein synthesis of Leucine Zipper-fused Fab

    Fukui Kansuke, Yamamoto Hiroaki, Hashimura Dai, Kato Teruyo, Kojima Takaaki, Nakano Hideo

      Vol. 66   page: 197 - 197   2014

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Presentations 44

  1. アミノ酸配列に着目した翻訳されやすいタンパク質の設計技術開発 Invited

    加藤晃代、横山源太朗、本野千恵、西河佑馬、中野秀雄、浜田道昭

    第3回MfIP連携探索WS  2025.3.14  マス・フォア・インダストリ・プラットフォーム (MfIP)

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  2. 翻訳促進ペプチドタグに対するウサギモノクローナル抗体の取得

    山内香奈、木原もなみ、加藤晃代、中野秀雄

    化学工学会第90年会  2025.3.12 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:東京  

  3. 狂犬病ウイルスモノクローナル抗体探索

    中島琉葵、木原もなみ、加藤晃代、中野秀雄

    化学工学会第90年会  2025.3.12 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

  4. 狂犬病ウイルスに対するヒト・ウサギモノクローナル抗体の取得と医学獣医学応用

    中島琉葵、木原もなみ、加藤晃代、中野秀雄

    第2回COMITシンポジウム  2025.3.7 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  5. 短いペプチドによる翻訳促進現象とタンパク質生産性向上に向けた応用展開

    加藤 晃代

    日本農芸化学会2025年度札幌大会  2025.3.6 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:札幌  

  6. 翻訳促進ペプチドと大腸菌発現系によるヒト由来酵素の生産量向上検討

    内山さくら、安藤知佳、恒松雄太、中野秀雄、加藤晃代

    日本農芸化学会2025年度札幌大会  2025.3.6 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  7. 出芽酵母における翻訳促進新生鎖の探索と応用

    岡田航輝、間部悟司、加藤晃代、朱博、北口哲也、中野秀雄

    日本農芸化学会2025年度札幌大会  2025.3.6 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  8. cDNAディスプレイ技術による大腸菌翻訳促進ペプチドの探索

    下地理子、藤川璃子、中野秀雄、加藤晃代

    日本農芸化学会2025年度札幌大会  2025.3.6 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  9. 翻訳促進ペプチドによる翻訳アレスト解除とその速度論的解析

    西河佑馬, 加藤晃代, 中野秀雄

    日本農芸化学会2025年度札幌大会  2025.3.6 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  10. 真核系無細胞タンパク質合成系を用いた翻訳促進新生鎖の探索

    高井陸杜、加藤晃代 、中野秀雄

    日本農芸化学会2025年度札幌大会  2025.3.6 

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    Event date: 2025.3

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  11. ペプチドによる翻訳促進とタンパク質生産増大に関する研究 Invited

    加藤 晃代

    大隅基礎科学創成財団微生物コンソーシアム定例会  2025.1.31  大隅基礎科学創成財団

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    Event date: 2025.1

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:オンライン  

  12. Microbial application for the industry and efficient production of recombinant proteins Invited International conference

    Teruyo KATO

    2024 Sakura-Bio Meeting  2024.12.16 

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    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (invited, special)  

    Venue:Onna (Okinawa)   Country:Japan  

  13. Development of monoclonal antibody targeting membrane protein utilizing in vitro system

    Daffa Sean ADINEGORO, Teruyo KATO, Hideo NAKANO

    2024 Sakura-Bio Meeting  2024.12.16 

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    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Venue:Onna (Okinawa)   Country:Japan  

  14. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo KATO

    2024 Sakura-Bio Meeting  2024.12.17 

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    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Onna (Okinawa)   Country:Japan  

  15. Analysis of intestinal bacteria-binding monoclonal antibodies derived from rabbit single B cells using the Brevibacillus choshinensis expression system International conference

    Khairil ANWAR, Daffa Sean ADINEGORO, Monami KIHARA, Teruyo OJIMA-KATO, Hideo NAKANO

    2024 Sakura-Bio Meeting  2024.12 

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    Event date: 2024.12

    Language:English   Presentation type:Oral presentation (general)  

  16. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    24th AAACU Biennial Conference and General Assembly  2024.12 

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    Event date: 2024.12

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  17. 博士の様々な選択肢の一例 Invited

    加藤 晃代

    生命系卓越大学院共創シンポジウム  2024.11.14 

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    Event date: 2024.11

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:名古屋  

  18. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    2024.11 

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    Event date: 2024.11

    Language:Japanese   Presentation type:Poster presentation  

  19. 再構成系無細胞タンパク質合成系を利用した抗体機能評価とエンジニアリング Invited

    加藤 晃代, 中野 秀雄

    第47回日本分子生物学会年会シンポジウム「アカデミア創薬」  2024.11 

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    Event date: 2024.11

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:福岡  

  20. cDNAディスプレイ法による翻訳促進新生ペプチドの探索

    藤川 璃子, 下地 理子, 中野 秀雄, 加藤 晃代

    第4回天野エンザイム酵素研究助成報告会  2024.11 

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    Event date: 2024.11

    Language:Japanese   Presentation type:Poster presentation  

  21. タンパク質生産量増大に向けた翻訳促進ペプチドの利用検討

    岡田 杏梨, 加藤 晃代, 佐分利 亘, 中野 秀雄

    第4回天野エンザイム酵素研究助成報告会  2024.11 

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    Event date: 2024.11

    Venue:名古屋  

  22. 出芽酵母における翻訳促進新生鎖の探索

    岡田 航輝, 間部 悟司, 加藤 晃代, 朱 博, 北口 哲也, 中野 秀雄

    第4回天野エンザイム酵素研究助成報告会  2024.11 

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    Event date: 2024.11

    Language:Japanese   Presentation type:Poster presentation  

  23. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis

    2024.10 

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    Event date: 2024.11

  24. Enhanced Production of Phospholipase D from Streptomyces antibioticus in Escherichia coli Cytoplasmic Expression System using Translation Enhancing Peptides

    Lalu UNSUNNIDHAL, Teruyo OJIMA-KATO, Jasmina DAMNJANOVIC, Hideo NAKANO

    2024.11 

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    Event date: 2024.11

    Language:English   Presentation type:Poster presentation  

  25. 翻訳促進ペプチドタグを用いた酵素の低生産性解消技術の開発

    加藤 晃代

    第4回天野エンザイム酵素研究助成報告会  2024.11 

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    Event date: 2024.11

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋  

  26. Influence of the Translation-Enhancing peptide tag on the ribosomal stalling induced by arrest peptide in cell-free protein synthesis International conference

    Yuma NISHIKAWA, Hideo NAKANO, Teruyo OJIMA-KATO

    29th Symposium of Young Asian Biological Engineers' Community  2024.10 

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    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Country:Korea, Republic of  

  27. 翻訳効率の改変技術開発 Invited

    加藤 晃代

    第37回日本微生物生態学会  2024.10 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:広島  

  28. 翻訳促進ペプチドの開発とタンパク質機能解析への応用 Invited

    加藤 晃代

    第74回日本放線菌学会学術講演会  2024.10 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Venue:東京  

  29. Antibody screening and engineering technology using cell-free protein synthesis Invited International conference

    Teruyo OJIMA-KATO, Hideo NAKANO

    29th Symposium of Young Asian Biological Engineers' Community  2024.10 

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    Event date: 2024.10

    Language:English   Presentation type:Symposium, workshop panel (public)  

    Venue:Pusan   Country:Korea, Republic of  

  30. Obtaining human monoclonal antibodies against intestinal bacteria

    Monami KIHARA, Teruyo OJIMA-KATO, Sayaka KONDO, Yukine YOKOO, Hideo NAKANO

    29th Symposium of Young Asian Biological Engineers' Community  2024.10 

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    Event date: 2024.10

    Language:English   Presentation type:Poster presentation  

    Venue:Pusan   Country:Korea, Republic of  

  31. リボソームディスプレイによる抗腸内細菌 ヒトモノクローナル抗体取得法の開発

    木原 もなみ, 横尾 幸音, 近藤 冴香, 加藤 晃代, 中野 秀雄

    第76回日本生物工学会  2024.9  日本生物工学会

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    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  32. cDNAディスプレイ法による翻訳促進新生ペプチドの探索

    藤川 璃子, 下地 理子, 中野 秀雄, 加藤 晃代

    日本農芸化学会中部支部第199回例会  2024.9 

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    Event date: 2024.9

    Venue:名古屋  

  33. リボソームディスプレイと微生物分泌発現系を用いた抗PAタグ抗体の親和性成熟技術の開発

    岡田 杏梨, 木原 もなみ, 奥田 理央, 加藤 晃代, 中野 秀雄

    日本農芸化学会中部支部第199回例会  2024.9 

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    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  34. 抗狂犬病ウイルスモノクローナル抗体探索

    中島 琉葵, 中野 秀雄, 加藤 晃代, 木原 もなみ

    日本農芸化学会中部支部第199回例会  2024.9 

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    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

  35. 出芽酵母における翻訳促進新生鎖の探索

    岡田 航輝, 間部 悟司, 加藤 晃代, 朱 博, 北口 哲也, 中野 秀雄

    日本農芸化学会中部支部第199回例会  2024.9 

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    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

  36. SKIKペプチドタグに対するウサギモノクロ―ナル抗体の取得

    山内 香奈, 木原 もなみ, 加藤 晃代, 中野 秀雄

    日本農芸化学会中部支部第199回例会  2024.9 

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    Event date: 2024.9

    Language:Japanese   Presentation type:Poster presentation  

    Venue:名古屋  

  37. 微生物由来トランスグルタミナーゼの基質プロファイリングとその優先配列の探索

    大庭 侑起, Jasmina DAMNJANOVIC, 中野 秀雄, 加藤 晃代, 人見 清隆, T. I. Kalhari MUNAWEERA

    第76回日本生物工学会  2024.9  日本生物工学会

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    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  38. 翻訳促進新生ペプチドを用いた連続プロリンを有するタンパク質の生産性向上技術の開発

    藤川 璃子, 中野 秀雄, 加藤 晃代

    第76回日本生物工学会  2024.9  日本生物工学会

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    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  39. リボソームディスプレイと微生物分泌発現系を用いた抗PAタグ抗体の親和性成熟技術の開発

    岡田 杏梨, 中野 秀雄, 加藤 晃代, 木原 もなみ, 奥田 理央

    第76回日本生物工学会  2024.9  日本生物工学会

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    Event date: 2024.9

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:東京  

  40. 大腸菌による Fab 抗体の生産と自動リフォールディング技術の開発

    Hoang Anh Tung, 加藤 晃代, 中野 秀雄

    2024年度日本生物工学会中部支部例会・中部支部30周年記念講演会  2024.8 

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    Event date: 2024.8

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:名古屋  

  41. Development of a method for collecting monoclonal antibodies against intestinal bacteria International conference

    Monami KIHARA, Teruyo KATO, Sayaka KONDO, Yukine YOKOO, Hideo NAKANO

    Glyco-core Symposium 2024  2024.7 

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    Event date: 2024.7

    Language:English   Presentation type:Poster presentation  

    Venue:Nagoya  

  42. 翻訳促進ペプチドによるタンパク質生産効率化 Invited

    加藤 晃代

    第24回日本蛋白質科学会年会ワークショップ  2024.6 

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    Event date: 2024.6

    Language:Japanese   Presentation type:Symposium, workshop panel (public)  

    Venue:札幌  

  43. 翻訳促進ペプチドによる翻訳アレスト解除とその速度論的解析

    西河 佑馬, 加藤 晃代, 中野 秀雄

    第24回日本蛋白質科学会年会  2024.6  日本蛋白質科学会

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    Event date: 2024.6

    Language:Japanese   Presentation type:Poster presentation  

    Venue:札幌  

  44. Research on Translation Enhancing nascent Peptides Invited International conference

    Teruyo KATO

    2024.5 

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    Event date: 2024.5

    Language:English   Presentation type:Poster presentation  

    Venue:Strasburg   Country:France  

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Research Project for Joint Research, Competitive Funding, etc. 4

  1. 翻訳されやすいタンパク質の設計技術開発

    2023.10 - 2024.3

    革新的GX技術創出事業(GteX)バイオものづくり  革新的要素技術研究

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\13000000 ( Direct Cost: \100000000 、 Indirect Cost:\3000000 )

  2. 翻訳制御機構の解明とバイオ産業への応用

    Grant number:JPMJFR2204  2023.4

    創発的研究支援事業   創発的研究支援事業

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    Authorship:Principal investigator  Grant type:Competitive

  3. 翻訳促進新生鎖の網羅的探索とルール解明

    Grant number:23K04989  2023.4 - 2026.3

    科学研究費助成事業   基盤研究(C)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\46800000 ( Direct Cost: \3600000 、 Indirect Cost:\1080000 )

  4. 翻訳されやすいタンパク質のデザインに向けた研究

    2022.10

    産総研ー名古屋大学アライアンス事業 

    加藤晃代、本野千恵、中野秀雄

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    Authorship:Principal investigator  Grant type:Collaborative (industry/university)

    Grant amount:\800000 ( Direct Cost: \800000 )

KAKENHI (Grants-in-Aid for Scientific Research) 7

  1. 翻訳されやすいタンパク質の設計技術開発

    2023.10 - 2024.3

    国立研究開発法人科学技術振興機構  革新的GX技術創出事業(GteX)  革新的要素技術研究

    加藤晃代、中野秀雄、本野千恵、浜田道昭、横山源太朗

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\13000000 ( Direct Cost: \10000000 、 Indirect Cost:\3000000 )

  2. 翻訳制御機構の解明とバイオ産業への応用

    Grant number:JPMJFR2204  2023.4

    国立研究開発法人科学技術振興機構  創発的研究支援事業   創発的研究支援事業

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    Authorship:Principal investigator  Grant type:Competitive

  3. 新生鎖による翻訳促進機構に関する研究

    Grant number:20K05806  2020.4 - 2023.3

    日本学術振興会  科学研究費助成事業   基盤研究(C)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct Cost: \3300000 、 Indirect Cost:\990000 )

  4. タンパク質発現可能化ルールの解明

    Grant number:18K19187  2018.6 - 2020.3

    日本学術振興会  科学研究費助成事業   挑戦的研究(萌芽)

    田村廣人

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\6370000 ( Direct Cost: \4900000 、 Indirect Cost:\1470000 )

  5. 難発現タンパク質の生産可能化技術構築

    Grant number:18K14392  2018.4 - 2020.3

    日本学術振興会  科学研究費助成事業   若手研究

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    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

  6. 転写翻訳速度制御因子の探索と制御機構の解明

    2017.4 - 2018.3

    特別研究員奨励費

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    Authorship:Principal investigator  Grant type:Competitive

  7. Development of a nanostructured hybrid antibody molecule with DNA scaffold

    Grant number:26820360  2014.4 - 2016.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (B)

    Kato Teruyo

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    Authorship:Principal investigator 

    Grant amount:\4030000 ( Direct Cost: \3100000 、 Indirect Cost:\930000 )

    Antibodies have become essential tool in the life technology fields and their applications as a high-sensitivity sensor are increasing.
    In this research, we have developed a novel sensor molecule named ‘Hybribody’ which consists of DNA (PCR product or plasmid), DNA-binding protein, and antibody (scFv). First, we established an efficient production scheme for fusion proteins of DNA-binding protein and scFv using E. coli expression systems with an N-teminal tag and chaperon co-expression. Bivalent antibody-DNA hybrid molecule, Hybribody, was formed by mixing with the purified proteins and DNA fragments.

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Industrial property rights 1

  1. タグ含有タンパク質、翻訳鋳型mRNA、発現ベクター、タグ含有タンパク質の生産方法

    加藤晃代、中野秀雄、本野千恵、浜田道昭、横山源太朗

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    Applicant:名古屋大学、産業技術総合研究所

    Application no:特願2024-232917  Date applied:2024.12

 

Social Contribution 3

  1. 2025年度産学官学術交流フォーラム

    Role(s):Presenter, Planner, Report writing

    日本農芸化学会産学官若手交流会  2025.3

  2. ペプチドによる翻訳促進とタンパク質生産増大に関する研究

    Role(s):Lecturer

    大隅基礎科学創成財団微生物コンソーシアム  2025.1

  3. さんわか×北大 ミニセミナー「産官学の現場から語る研究者のリアル」

    Role(s):Planner, Organizing member

    日本農芸化学会産学官若手交流会 さんわか  2024.7

Media Coverage 1

  1. Improving Protein Production: The Role of Nascent MSKIK Peptide in E. coli Internet

    Medicine Innovates  2023.12

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    Author:Other 

Academic Activities 2

  1. 日本農芸化学会産学官若手交流会さんわかセミナー実行委員

    Role(s):Planning, management, etc.

    2023.4

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    Type:Academic society, research group, etc. 

  2. 日本生物工学会若手研究者の集いセミナー実行委員

    Role(s):Planning, management, etc.

    2023.4 - 2024.9

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    Type:Academic society, research group, etc.