2024/04/02 更新

写真a

ニブ　ユタカ
二歩　裕
NIBU Yutaka
所属
糖鎖生命コア研究所 戦略推進室 特任准教授
職名
特任准教授

経歴 7

  1. 東海国立大学機構 名古屋大学   糖鎖生命コア研究所（iGCORE）   特任准教授（研究マネジメント）

    2022年5月 - 現在

  2. 東京農工大学   先端産学連携研究推進センター   特任講師、リサーチ・アドミニストレーター

    2018年 - 2022年4月

  3. 筑波大学   URA研究戦略推進室   リサーチ・アドミニストレーター

    2015年

  4. Weill Cornell Medicine   Department of Cell and Developmental Biology   Assistant Professor

    2002年

    　 詳細を見る

    国名：アメリカ合衆国

  5. 日本学術振興会 海外特別研究員

    1998年 - 2000年

  6. University of California at Berkeley   Department of Molecular and Cell Biology   Postdoctoral Fellow, Associate Specialist

    1997年

    　 詳細を見る

    国名：アメリカ合衆国

  7. 筑波大学   応用生物化学系   助手

    1995年

▼全件表示

経歴の先頭へ▲

学歴 1

  1. 筑波大学   農学研究科 応用生物化学専攻

    - 1995年

学歴の先頭へ▲

所属学協会 6

  1. リサーチ・アドミニストレーター協議会

    2015年 - 現在

  2. The Genetics Society of America

    2002年 - 2013年

  3. The Society for Developmental Biology

    2002年 - 2013年

  4. American Association for the Advancement of Science

    1998年 - 2004年

  5. 日本分子生物学会

    1992年 - 2002年

  6. 日本生化学会

    1992年 - 1997年

▼全件表示

所属学協会の先頭へ▲
 

論文 28

  1. Natto extract, a Japanese fermented soybean food, directly inhibits viral infections including SARS-CoV-2 in vitro 査読有り

    Mami Oba, Wen Rongduo, Akatsuki Saito, Tamaki Okabayashi, Tomoko Yokota, Junko Yasuoka, Yoko Sato, Koji Nishifuji, Hitoshi Wake, Yutaka Nibu, Tetsuya Mizutani

    Biochemical and Biophysical Research Communications   570 巻   頁： 21 - 25   2021年9月

    　詳細を見る

    掲載種別：研究論文（学術雑誌）   出版者・発行元：Elsevier {BV}  

    DOI： 10.1016/j.bbrc.2021.07.034

  2. The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster 査読有り

    Sano Hiroko, Nakamura Akira, Texada Michael J., Truman James W., Ishimoto Hiroshi, Kamikouchi Azusa, Nibu Yutaka, Kume Kazuhiko, Ida Takanori, Kojima Masayasu

    PLOS GENETICS   11 巻 ( 5 ) 頁： e1005209   2015年5月

    　詳細を見る

    記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：PLoS Genetics  

    The coordination of growth with nutritional status is essential for proper development and physiology. Nutritional information is mostly perceived by peripheral organs before being relayed to the brain, which modulates physiological responses. Hormonal signaling ensures this organ-to-organ communication, and the failure of endocrine regulation in humans can cause diseases including obesity and diabetes. In Drosophila melanogaster, the fat body (adipose tissue) has been suggested to play an important role in coupling growth with nutritional status. Here, we show that the peripheral tissue-derived peptide hormone CCHamide-2 (CCHa2) acts as a nutrient-dependent regulator of Drosophila insulin-like peptides (Dilps). A BAC-based transgenic reporter revealed strong expression of CCHa2 receptor (CCHa2-R) in insulin-producing cells (IPCs) in the brain. Calcium imaging of brain explants and IPC-specific CCHa2-R knockdown demonstrated that peripheral-tissue derived CCHa2 directly activates IPCs. Interestingly, genetic disruption of either CCHa2 or CCHa2-R caused almost identical defects in larval growth and developmental timing. Consistent with these phenotypes, the expression of dilp5, and the release of both Dilp2 and Dilp5, were severely reduced. Furthermore, transcription of CCHa2 is altered in response to nutritional levels, particularly of glucose. These findings demonstrate that CCHa2 and CCHa2-R form a direct link between peripheral tissues and the brain, and that this pathway is essential for the coordination of systemic growth with nutritional availability. A mammalian homologue of CCHa2-R, Bombesin receptor subtype-3 (Brs3), is an orphan receptor that is expressed in the islet β-cells; however, the role of Brs3 in insulin regulation remains elusive. Our genetic approach in Drosophila melanogaster provides the first evidence, to our knowledge, that bombesin receptor signaling with its endogenous ligand promotes insulin production.

    DOI： 10.1371/journal.pgen.1005209

    Web of Science

    Scopus

    PubMed

  3. Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord 査読有り

    José-Edwards Diana S., Oda-Ishii Izumi, Kugler Jamie E., Passamaneck Yale J., Katikala Lavanya, Nibu Yutaka, Di Gregorio Anna

    PLOS Genetics   11 巻 ( 12 )   2015年

    　詳細を見る

    記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Public Library of Science  

    A main challenge of modern biology is to understand how specific constellations of genes are activated to differentiate cells and give rise to distinct tissues. This study focuses on elucidating how gene expression is initiated in the notochord, an axial structure that provides support and patterning signals to embryos of humans and all other chordates. Although numerous notochord genes have been identified, the regulatory DNAs that orchestrate development and propel evolution of this structure by eliciting notochord gene expression remain mostly uncharted, and the information on their configuration and recurrence is still quite fragmentary. Here we used the simple chordate Ciona for a systematic analysis of notochord cis-regulatory modules (CRMs), and investigated their composition, architectural constraints, predictive ability and evolutionary conservation. We found that most Ciona notochord CRMs relied upon variable combinations of binding sites for the transcription factors Brachyury and/or Foxa2, which can act either synergistically or independently from one another. Notably, one of these CRMs contains a Brachyury binding site juxtaposed to an (AC) microsatellite, an unusual arrangement also found in Brachyury-bound regulatory regions in mouse. In contrast, different subsets of CRMs relied upon binding sites for transcription factors of widely diverse families. Surprisingly, we found that neither intra-genomic nor interspecific conservation of binding sites were reliably predictive hallmarks of notochord CRMs. We propose that rather than obeying a rigid sequence-based cis-regulatory code, most notochord CRMs are rather unique. Yet, this study uncovered essential elements recurrently used by divergent chordates as basic building blocks for notochord CRMs.

    DOI： 10.1371/journal.pgen.1005730

    Scopus

  4. From notochord formation to hereditary chordoma: The many roles of brachyury 査読有り

    Nibu, Y., José-Edwards, D.S., Di Gregorio, A.

    BioMed Research International   2013 巻   頁： 1 - 14   2013年

    　詳細を見る

    担当区分：筆頭著者,　責任著者   掲載種別：研究論文（学術雑誌）   出版者・発行元：Hindawi Limited  

    Chordoma is a rare, but often malignant, bone cancer that preferentially affects the axial skeleton and the skull base. These tumors are both sporadic and hereditary and appear to occur more frequently after the fourth decade of life; however, modern technologies have increased the detection of pediatric chordomas. Chordomas originate from remnants of the notochord, the main embryonic axial structure that precedes the backbone, and share with notochord cells both histological features and the expression of characteristic genes. One such gene is<italic>Brachyury</italic>, which encodes for a sequence-specific transcription factor. Known for decades as a main regulator of notochord formation,<italic>Brachyury</italic>has recently gained interest as a biomarker and causative agent of chordoma, and therefore as a promising therapeutic target. Here, we review the main characteristics of chordoma, the molecular markers, and the clinical approaches currently available for the early detection and possible treatment of this cancer. In particular, we report on the current knowledge of the role of<italic>Brachyury</italic>and of its possible mechanisms of action in both notochord formation and chordoma etiogenesis.

    DOI： 10.1155/2013/826435

    Scopus

  5. Optimization of a Method for Chromatin Immunoprecipitation Assays in the Marine Invertebrate Chordate Ciona 査読有り

    Aihara, H., Katikala, L., Zeller, R.W., Di Gregorio, A., Nibu, Y.

    Marine Biotechnology   15 巻 ( 5 ) 頁： 520 - 525   2013年

    　詳細を見る

    担当区分：最終著者,　責任著者   掲載種別：研究論文（学術雑誌）   出版者・発行元：Springer Science and Business Media LLC  

    DOI： 10.1007/s10126-013-9504-5

    Scopus

  6. Functional Brachyury Binding Sites Establish a Temporal Read-out of Gene Expression in the Ciona Notochord 査読有り

    Katikala Lavanya, Aihara Hitoshi, Passamaneck Yale J., Gazdoiu Stefan, José-Edwards Diana S., Kugler Jamie E., Oda-Ishii Izumi, Imai Janice H., Nibu Yutaka, Di Gregorio Anna

    PLoS Biology   11 巻 ( 10 ) 頁： e1001697   2013年

    　詳細を見る

    担当区分：最終著者,　責任著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Public Library of Science  

    The appearance of the notochord represented a milestone in Deuterostome evolution. The notochord is necessary for the development of the chordate body plan and for the formation of the vertebral column and numerous organs. It is known that the transcription factor Brachyury is required for notochord formation in all chordates, and that it controls transcription of a large number of target genes. However, studies of the structure of the cis-regulatory modules (CRMs) through which this control is exerted are complicated in vertebrates by the genomic complexity and the pan-mesodermal expression territory of Brachyury. We used the ascidian Ciona, in which the single-copy Brachyury is notochord-specific and CRMs are easily identifiable, to carry out a systematic characterization of Brachyury-downstream notochord CRMs. We found that Ciona Brachyury (Ci-Bra) controls most of its targets directly, through non-palindromic binding sites that function either synergistically or individually to activate early- and middle-onset genes, respectively, while late-onset target CRMs are controlled indirectly, via transcriptional intermediaries. These results illustrate how a transcriptional regulator can efficiently shape a shallow gene regulatory network into a multi-tiered transcriptional output, and provide insights into the mechanisms that establish temporal read-outs of gene expression in a fast-developing chordate embryo.

    DOI： 10.1371/journal.pbio.1001697

    Scopus

  7. Akirin links twist-regulated transcription with the brahma chromatin remodeling complex during embryogenesis 査読有り

    Nowak Scott J., Aihara Hitoshi, Gonzalez Katie, Nibu Yutaka, Baylies Mary K.

    PLoS Genetics   8 巻 ( 3 ) 頁： e1002547   2012年

    　詳細を見る

    記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：Public Library of Science  

    The activities of developmentally critical transcription factors are regulated via interactions with cofactors. Such interactions influence transcription factor activity either directly through protein-protein interactions or indirectly by altering the local chromatin environment. Using a yeast double-interaction screen, we identified a highly conserved nuclear protein, Akirin, as a novel cofactor of the key Drosophila melanogaster mesoderm and muscle transcription factor Twist. We find that Akirin interacts genetically and physically with Twist to facilitate expression of some, but not all, Twist-regulated genes during embryonic myogenesis. akirin mutant embryos have muscle defects consistent with altered regulation of a subset of Twist-regulated genes. To regulate transcription, Akirin colocalizes and genetically interacts with subunits of the Brahma SWI/SNF-class chromatin remodeling complex. Our results suggest that, mechanistically, Akirin mediates a novel connection between Twist and a chromatin remodeling complex to facilitate changes in the chromatin environment, leading to the optimal expression of some Twist-regulated genes during Drosophila myogenesis. We propose that this Akirin-mediated link between transcription factors and the Brahma complex represents a novel paradigm for providing tissue and target specificity for transcription factor interactions with the chromatin remodeling machinery.

    DOI： 10.1371/journal.pgen.1002547

    Scopus

  8. Tbx2/3 is an essential mediator within the brachyury gene network during Ciona notochord development 査読有り

    José-Edwards, D.S., Oda-Ishii, I., Nibu, Y., Di Gregorio, A.

    Development (Cambridge)   140 巻 ( 11 )   2012年

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    担当区分：最終著者,　責任著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1242/dev.094227

    Scopus

  9. CtBP is required for proper development of peripheral nervous system in Drosophila 査読有り

    Stern, M.D., Aihara, H., Roccaro, G.A., Cheung, L., Zhang, H., Negeri, D., Nibu, Y.

    Mechanisms of Development   126 巻 ( 1-2 )   2009年

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    担当区分：最終著者,　責任著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1016/j.mod.2008.10.003

    Scopus

  10. Drosophila Ebi mediates Snail-dependent transcriptional repression through HDAC3-induced histone deacetylation 査読有り

    Qi, D., Bergman, M., Aihara, H., Nibu, Y., Mannervik, M.

    EMBO Journal   27 巻 ( 6 )   2008年

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    掲載種別：研究論文（学術雑誌）  

    DOI： 10.1038/emboj.2008.26

    Scopus

  11. Structurally related Arabidopsis ANGUSTIFOLIA is functionally distinct from the transcriptional corepressor CtBP 査読有り

    Stern, M.D., Aihara, H., Cho, K.-H., Kim, G.-T., Horiguchi, G., Roccaro, G.A., Guevara, E., Sun, H.H., Negeri, D., Tsukaya, H., Nibu, Y.

    Development Genes and Evolution   217 巻 ( 11-12 )   2007年

    　詳細を見る

    担当区分：最終著者,　責任著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1007/s00427-007-0186-8

    Scopus

  12. The acetyltransferase activity of Drosophila CBP is dispensable for regulation of the Dpp pathway in the early embryo 査読有り

    Lilja, T., Aihara, H., Stabell, M., Nibu, Y., Mannervik, M.

    Developmental Biology   305 巻 ( 2 )   2007年

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    掲載種別：研究論文（学術雑誌）  

    DOI： 10.1016/j.ydbio.2007.01.036

    Scopus

  13. Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene. 査読有り

    Date, S., Nibu, Y., Yanai, K., Hirata, J., Yagami, K., Fukamizu, A.

    International journal of molecular medicine   13 巻 ( 5 )   2004年

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    掲載種別：研究論文（学術雑誌）  

    Scopus

  14. CtBP-independent repression in the Drosophila embryo 査読有り

    Nibu, Y., Senger, K., Levine, M.

    Molecular and Cellular Biology   23 巻 ( 11 )   2003年

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    担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1128/MCB.23.11.3990-3999.2003

    Scopus

  15. Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome 査読有り

    Berman, B.P., Nibu, Y., Pfeiffer, B.D., Tomancak, P., Celniker, S.E., Levine, M., Rubin, G.M., Eisen, M.B.

    Proc. Natl Acad. Sci. USA   99 巻 ( 2 ) 頁： 757 - 757   2002年

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    掲載種別：研究論文（学術雑誌）  

    DOI： 10.1073/pnas.231608898

    Scopus

  16. CtBP-dependent activities of the short-range giant repressor in the Drosophila embryo 査読有り

    Nibu, Y., Levine, M.S.

    Proceedings of the National Academy of Sciences of the United States of America   98 巻 ( 11 )   2001年

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    担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1073/pnas.111158298

    Scopus

  17. Local action of long-range repressors in the Drosophila embryo 査読有り

    Nibu, Y., Zhang, H., Levine, M.

    EMBO Journal   20 巻 ( 9 )   2001年

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    担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1093/emboj/20.9.2246

    Scopus

  18. Regulated expression of human angiotensinogen gene by hepatocyte nuclear factor 4 and chicken ovalbumin upstream promoter-transcription factor 査読有り

    Yanai, K., Hirota, K., Taniguchi-Yanai, K., Shigematsu, Y., Shimamoto, Y., Saito, T., Chowdhury, S., Takiguchi, M., Arakawa, M., Nibu, Y., Sugiyama, F., Yagami, K.-I., Fukamizu, A.

    Journal of Biological Chemistry   274 巻 ( 49 )   1999年

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    掲載種別：研究論文（学術雑誌）  

    DOI： 10.1074/jbc.274.49.34605

    Scopus

  19. Transcriptional coregulators in development 査読有り

    Mannervik, M., Nibu, Y., Zhang, H., Levine, M.

    Science   284 巻 ( 5414 ) 頁： 606 - 609   1999年

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    掲載種別：研究論文（学術雑誌）  

    DOI： 10.1126/science.284.5414.606

    Scopus

  20. dCtBP mediates transcriptional repression by Knirps, Kruppel and Snail in the Drosophila embryo 査読有り

    Nibu, Y., Zhang, H., Bajor, E., Barolo, S., Small, S., Levine, M.

    EMBO J.   17 巻 ( 23 ) 頁： 7009 - 7020   1998年

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    担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）  

    Scopus

  21. Interaction of short-range repressors with Drosophila CtBP in the embryo 査読有り

    Nibu, Y., Zhang, H., Levine, M.

    Science   280 巻 ( 5360 ) 頁： 101 - 103   1998年

    　詳細を見る

    担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1126/science.280.5360.101

    Scopus

  22. The tumor suppressor protein CtBP mediates short-range repression in the Drosophila embryo

    Nibu, Y., Zhang, H., Ohtsuki, S., Levine, M.

    FASEB Journal   12 巻 ( 8 )   1998年

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    掲載種別：研究論文（学術雑誌）  

    Scopus

  23. Characterization of a novel Alginate Lyase from Flavobacterium multivolum K-11. 査読有り

    Takeuchi T, Nibu Y, Murata K, Yoshida S, Kusakabe I

    Food Sci. Technol. Int.   3 巻 ( 4 ) 頁： 288 - 392   1997年

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    記述言語：英語   出版者・発行元：Japanese Society for Food Science and Technology  

    An alginate lyase was purified from an extracellular enzyme (commercial preparation) of <I>Flavobacterium multivolum </I>K-11 by successive column chromatographies, such as cation exchange, chromatofocusing, and gel filtration. The purified enzyme migrated as a single band on SDS-PAGE and analytical isoelectric focusing. The molecular weight of the enzyme was 32,000 by SDS-PAGE and 33,000 by HPLC gel filtration chromatography, and the pI of the enzyme was 8.2 on isoelectric focusing. The enzyme exhibited maximum activity at pH 7.5 and 40°C, and was stable between pH 6.0 and 9.0, and at temperatures up to 20°C. The enzyme activity was remarkably inhibited by chemical compounds such as SDS, MIA, TNBS, and <I>N</I>-bromosuccinimide, while EDTA and PCMB had no effect on the enzyme activity. The enzyme decomposed both the G-block (guluronic acid content; 89%) and the M-block (mannuronic content; 92%) at nearly equal rates, and produced several kinds of unsaturated oligomers. Because such activity of alginate lyase has not been reported, we believe that this is a novel alginate lyase.

    DOI： 10.3136/fsti9596t9798.3.388

  24. Purification and characterization of endo Poly (alpha-L-Guluronate) Lyase in the enzyme system from Flavobacterium multivolum. 査読有り

    Takeuchi T, Nibu Y, Murata K, Kusakabe I

    Food Sci. Technol. Int.   3 巻 ( 1 ) 頁： 22 - 26   1997年

    　詳細を見る

    記述言語：英語   出版者・発行元：Japanese Society for Food Science and Technology  

    An alginate lyase was purified from a crude enzyme of <I>Flavobacterium multivolum</I> K-11 by successive column chromatographies, such as cation exchange, chromatofocusing, and gel filtration. The enzyme thus obtained migrated as a single band on SDS-PAGE. The relative molecular mass of the enzyme was 43-kDa by SDS-PAGE and 41-kDa by HPLC gel filtration chromatography. The isoelectric point of the enzyme was 8.7. The enzyme exhibited maximum activity at pH 8.0 and 40°C, and was stable in the pH range of 6.0 to 9.0 and at temperatures up to 30°C. The enzyme activity was remarkably inhibited by chemical compounds such as EDTA, PCMB, MIA, TNBS, and <I>N</I>-bromosuccinimide. The enzyme was specific for poly-guluronate and produced several kinds of oligomers. Thus, the results suggested that the enzyme was classified as endo poly (α-L-guluronate) lyase (EC 4.2.2.11).

    DOI： 10.3136/fsti9596t9798.3.22

  25. A cis-acting DNA element located between TATA box and transcription initiation site is critical in response to regulatory sequences in human angiotensinogen gene 査読有り

    Yanai, K., Nibu, Y., Murakami, K., Fukamizu, A.

    Journal of Biological Chemistry   271 巻 ( 27 )   1996年

    　詳細を見る

    掲載種別：研究論文（学術雑誌）  

    DOI： 10.1074/jbc.271.27.15981

    Scopus

  26. Human activin βA gene: Identification of novel 5′ exon, functional promoter, and enhancers 査読有り

    Tanimoto, K., Yoshida, E., Mita, S., Nibu, Y., Murakami, K., Fukamizu, A.

    Journal of Biological Chemistry   271 巻 ( 51 )   1996年

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    掲載種別：研究論文（学術雑誌）  

    Scopus

  27. Cloning of the rat angiotensin II type 2 receptor gene and identification of its functional promoter region

    Kobayashi, S.-i., Ohnishi, J., Nibu, Y., Nishimatsu, S.-i., Umemura, S., Ishii, M., Murakami, K., Miyazaki, H.

    BBA - Gene Structure and Expression   1262 巻 ( 2-3 )   1995年

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    担当区分：筆頭著者   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1016/0167-4781(95)00076-S

    Scopus

  28. Purification and Characterization of Extracellular Alginate Lyase from Enterobacter cloacae M-1 査読有り

    Nibu Yutaka, Satoh Toshihide, Nishi Yuji, Takeuchi Toshio, Murata Katsumi, Kusakabe Isao

    Bioscience, biotechnology, and biochemistry   59 巻 ( 4 ) 頁： 632 - 637   1995年

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    担当区分：筆頭著者   記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：社団法人日本農芸化学会  

    An alginate lyase from the culture supernatant of Enterobacter cloacae M-1 was purified by ammonium sulfate precipitation, cation-exchange chromatography (SP-Toyopearl), and gel filtration (Ultrogel AcA44). The final preparation thus obtained showed a single band on SDS-PAGE. The purified enzyme had the molecular weight of 38, 000 and 32, 000 by SDS-PAGE and gel filtration, respectively. The pI of the enzyme was 8. 9. The optimum pH and temperature for the enzyme reaction were around 7. 8 and 30℃, respectively. The enzyme was unstable on heating. EDTA completely inhibited the enzyme activity, but the activity was completely restored by the treatment with CaCl_2. The enzyme was specific for poly-guluronate and produced several kinds of unsaturated oligomers from the gluluronate. This suggested that the enzyme could be classified as an endo poly-guluronate lyase.

    DOI： 10.1080/bbb.59.632

    Scopus

    CiNii Books

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論文の先頭へ▲

書籍等出版物 7

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    二歩 裕, 伊藤 伸

    技術情報協会出版  2020年 

  4. 「戦略プロポーザル 環境調和型プラスチック戦略〜化学物質としてのプラスチックの安全な管理・活用を推進するための戦略的研究〜」CRDS-FY2019-SP-07（分担執筆）

    （ 範囲: 国立研究開発法人科学技術振興機構 研究開発戦略センター）

    国立研究開発法人科学技術振興機構  2020年 

  5. Transcriptional repression by the CtBP corepressor in Drosophila. In: CtBP Family Proteins (ed. D. Chinnadurai), Chapter 2, p18-27

    Aihara H, Perrone L, Nibu Y（ 範囲: Chapter 2, p18-27）

    Landes Bioscience  2007年 

  6. Transcriptional repressors and repression mechanisms. In: Gene Expression and Regulation (ed. J. Ma), Chapter 09, p159-173

    Perrone L, Aihara H, Nibu Y（ 範囲: Chapter 09, p159-173）

    Current Scientific Frontiers Book, Higher Education Press  2006年 

  7. レニン−アンジオテンシン系研究の新たな局面。アンジオテンシノーゲンの最近の話題を中心に。血管と内皮、6巻、5号、478-486

    二歩 裕, 深水昭吉

    1996年 

▼全件表示

書籍等出版物の先頭へ▲

MISC 2

  1. Regulated expression of human angiotensinogen gene by HNF4 and COUP-TF

    K Hirota, K Yanai, K Taniguchi-Yanai, Y Shigematsu, Y Shimamoto, T Saito, M Arakawa, Y Nibu, A Fukamizu  

    JOURNAL OF HYPERTENSION18 巻   頁： S183 - S183   2000年

    　詳細を見る

    記述言語：英語   掲載種別：研究発表ペーパー・要旨（国際会議）   出版者・発行元：LIPPINCOTT WILLIAMS & WILKINS  

    Web of Science

  2. ヒト・アンジオテンシノーゲン遺伝子の3'下流エンハンサー・コア領域の結合因子の機能解析

    伊達 昌一, 柳内 和幸, 二歩 裕, 村上 和雄, 深水 昭吉  

    日本分子生物学会年会プログラム・講演要旨集21 巻   頁： 397 - 397   1998年12月

    　詳細を見る

    記述言語：日本語  

    CiNii Books

MISCの先頭へ▲

講演・口頭発表等 10

  1. 東京農工大学におけるチーム型研究の推進とベンチャー創出・育成の取組

    齋藤 憲一郎, 二歩 裕, 前畑 英雄

    RA協議会第7回年次大会  2021年9月14日 

    　詳細を見る

    開催年月日： 2021年9月

  2. 民間企業からの投資のゆくえ -産学連携の伸びしろの可能性-

    佐野 恵利子, 伊藤 広幸, 二歩 裕

    RA協議会第7回年次大会  2021年9月14日 

    　詳細を見る

    開催年月日： 2021年9月

  3. A new strategy to facilitate academia-industry research collaboration and research expense hunting using disclosed information at University of Tsukuba.

    Sazawa H, Akutsu Y, Komatsubara S, Nukaga M, Ito M, Nibu Y, Baba T

    INORMS 2016 (The International Network of Research Management Societies)  2016年 

  4. 筑波大学の国際産学連携の方針と部局から生まれた社会での応用事例 招待有り

    二歩裕

    日本台湾産学連携推進セミナー（台北駐日経済文化代表処）  2016年 

  5. 研究マネジメント人材の獲得戦略 〜ニーズに呼応したトランスフォーメーション〜

    伊藤広幸, 佐野恵利子, 二歩 裕

    研究・イノベーション学会第37年次学術大会  2022年10月30日 

  6. 次世代の研究力マップ -博士人材育成を起源とする研究力指標-

    伊藤 広幸, 佐野 恵利子, 二歩 裕

    RA協議会第5回年次大会  2019年 

  7. 主要国における分野別論文数の動向 -2つの書誌データベースの特⻑を知り、活かして、上手に活用するには-」

    二歩 裕, 伊藤 広幸, 佐野 恵利子

    RA協議会第4回年次大会  2018年 

  8. URAの業務拡大と求められる専門性の変化(II)

    佐野 恵利子, 伊藤 広幸, 二歩 裕

    RA協議会第8回年次大会  2022年8月30日 

  9. URAの業務拡大と求められる専門性の変化

    佐野 恵利子, 伊藤 広幸, 二歩 裕

    RA協議会第6回年次大会  2020年 

  10. Strategy from building of interdisciplinary research to global collaborations at Tokyo University of Agriculture and Technology.

    Nibu Y, Saito K

    INORMS 2021 (The International Network of Research Management Societies )  2021年 

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講演・口頭発表等の先頭へ▲

その他研究活動 7

  1. 社会還元加速プログラム（SCORE）大学推進型（大学推進型（拠点都市環境整備型） 事業 『T-UNITE(Tokyo United Network for Innovation with Technology and Entrepreneurs)』 2021年度 起業家育成講座を運営する指導・支援人材の育成プログラム（コーチング研修、スタートアップ講座、デザイン思考コース）修了

    2022年

  2. Virtual Teaching and Learning Studio program (vTLS), Hasso Plattner Institute of Design (d.school), Stanford University

    2021年

  3. Waseda University T-UNITE – Babson Global Symposium for Entrepreneurship Educators 修了

    2021年

  4. JST 目利き人材育成研修、研究推進マネジメントコース 修了

    2018年

  5. 筑波大学Rcus大学マネジメントセミナー 修了

    2018年

  6. RA協議会リサーチアドミニストレーター新任研修 修了

    2016年

  7. JST プログラムマネージャー（PM）育成・活躍推進プログラム研修 修了

    2015年
    -
    2016年

▼全件表示

その他研究活動の先頭へ▲
 

社会貢献活動 1

  1. 講義 ニューヨーク市立小学校（PS78）

    役割：講師

    2012年

社会貢献活動の先頭へ▲

学術貢献活動 3

  1. RA協議会第6回年次大会 実行委員/セッション担当

    役割：企画立案・運営等

    2020年

  2. 写真提供 第一学習社「高等学校生物」と「最新図説生物」

    2013年

  3. Gene ControlのChapter 8: Gene Control and Cellular Signalling Pathways（第8章「遺伝子調節とシグナル伝達経路」）日本語訳

    2012年

学術貢献活動の先頭へ▲