Updated on 2023/09/29

写真a

 
UMEKUBO Nariyoshi
 
Organization
Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Organic Chemistry Assistant Professor
Graduate School
Graduate School of Pharmaceutical Sciences
Title
Assistant Professor

Degree 1

  1. 理学博士 ( 2021.3   東北大学 ) 

 

Papers 15

  1. Total Syntheses of Malettinins C and E Reviewed

    N. Umekubo, S. Yokoshima

    Org. Lett.   Vol. 25 ( 24 ) page: 4530 - 4533   2023.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.3c01565

  2. Pot-Economical Total Synthesis of Clinprost Reviewed

    Nariyoshi Umekubo, Yujiro Hayashi

    Org. Lett.     2020.11

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.0c03616

  3. Pot and time economies in the total synthesis of Corey lactone Invited Reviewed

    Nariyoshi Umekubo, Yurina Suga, Yujiro Hayashi

    Chem. Sci.     2019.12

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c9sc05824a

    Other Link: https://pubs.rsc.org/en/content/articlepdf/2020/sc/c9sc05824a

  4. Direct Asymmetric Michael Reaction of α,β-Unsaturated Aldehydes and Ketones Catalyzed by Two Secondary Amine Catalysts Reviewed

    Yujiro Hayashi, Nariyoshi Umekubo

    Angewandte Chemie International Edition     2017.12

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/anie.201710085

  5. Total Synthesis of Kopsone Reviewed

    Kazutoshi Tomoya , Kazuaki Komiya, Daisuke Nakajima, Nariyoshi Umekubo, Satoshi Yokoshima

    Organic Letters   Vol. 25 ( 25 ) page: 2718 - 2721   2023.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.3c00838

  6. Diphenylprolinol Silyl Ether Catalyzed Asymmetric Formal Carbo [3+3] Cycloaddition Reaction of Isopropylidenemalononitrile and α,β-Unsaturated Aldehyde Reviewed

    Nariyoshi Umekubo, Xiaolei Han, Naoki Mori, Yujiro Hayashi

    European Journal of Organic Chemistry   ( 26 ) page: e202200603   2022.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ejoc.202200603

  7. Catalytic Asymmetric Michael Reaction of Methyl Alkynyl Ketone Catalyzed by Diphenylprolinol Silyl Ether Invited Reviewed

    Nariyoshi Umekubo, Yujiro Hayashi

    ACS Organic & Inorganic Au   Vol. 2 ( 3 ) page: 245 - 251   2022.1

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsorginorgau.1c00054

  8. Asymmetric Synthesis of Pentasubstituted Cyclohexanes through Diphenylprolinol Silyl Ether Mediated Domino Michael/Michael Reaction Reviewed

    Amaechi Shedrack Odoh, Louise Aidanpää, Nariyoshi Umekubo, Hiroaki Matoba, Naoki Mori, Yujiro Hayashi

    Eur. J. Org. Chem.     2021.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ejoc.202101106

  9. Synthesis of Bicyclo[2.2.2]octanes with a Quaternary Bridgehead Carbon by Diphenylprolinol Silyl Ether-mediated Domino Reaction Reviewed

    Nariyoshi Umekubo, Tohru Taniguchi, Kenji Monde, Yujiro Hayashi

    Asian. J. Org. Chem.     2021.10

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/ajoc.202100573

  10. Asymmetric Domino Reaction of α,β-Unsaturated Aldehydes and α-Acyl α,β-Unsaturated Cyclic Ketones Catalyzed by Diphenylprolinol Silyl Ether Invited Reviewed

    Yujiro Hayashi, Yurina Suga, Nariyoshi Umekubo

    Org. Lett.     2020.10

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.0c03190

  11. Evidence for an enolate mechanism in the asymmetric Michael reaction of α,β-unsaturated aldehydes and ketones via a hybrid system of two secondary amine catalysts Reviewed

    Nariyoshi Umekubo, Takahiro Terunuma, Eunsang Kwon, Yujiro Hayashi

    Chem. Sci.     2020.9

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/d0sc03359f

    Other Link: https://pubs.rsc.org/en/content/articlepdf/2020/sc/d0sc03359f

  12. Asymmetric Synthesis of Corey Lactone and Latanoprost Reviewed

    Nariyoshi Umekubo, Yujiro Hayashi

    Eur. J. Org. Chem.     2020.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  13. Asymmetric One-Pot Mukaiyama Michael/Michael Reaction Catalyzed by Diphenylprolinol Silyl Ether Reviewed

    Nariyoshi Umekubo, Yujiro Hayashi

    Eur. J. Org. Chem.     2020.7

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    Authorship:Lead author  

    DOI: 10.1002/ejoc.202000925

  14. One-pot Synthesis of Chiral cis-Hydrindanes via Diphenylprolinol Silyl Ether Mediated Domino Reaction and Aldol Condensation Reviewed

    Nariyoshi Umekubo, Ryohei Iwata, Yujiro Hayashi

    Chem. Lett.     2020.4

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1246/cl.200297

  15. Prolinate Salts as Catalysts for α-Aminoxylation of Aldehyde and Associated Mechanistic Insights Reviewed

    Yujiro Hayashi, Taku Hirama, Nariyoshi Umekubo

    Org. Lett.     2017.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acs.orglett.7b01433

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KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. トロポン構造を含む多環式骨格構築法の開発とそれを利用した全合成

    Grant number:23K14321  2023.4 - 2025.3

    日本学術振興会  若手研究 

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    Authorship:Principal investigator 

    Grant amount:\4420000 ( Direct Cost: \3400000 、 Indirect Cost:\1020000 )

  2. 電気合成化学を用いたモルヒネおよびその類縁体の短工程合成研究

    Grant number:21J00473  2021.4 - 2021.12

    日本学術振興会  特別研究員奨励費 

  3. 連続的不斉マイケル反応を利用した多様な環骨格構築及びカルノシン酸の全合成

    Grant number:19J10974  2019.4 - 2021.3

    日本学術振興会  特別研究員(DC2)