Updated on 2023/01/05

写真a

 
AKIYAMA Hirokazu
 
Organization
Graduate School of Engineering Biomolecular Engineering 2 Assistant Professor
Graduate School
Graduate School of Engineering
Undergraduate School
School of Engineering Chemistry and Biotechnology
Title
Assistant Professor
Contact information
メールアドレス
External link

Degree 1

  1. Doctor of Engineering ( 2011.3   Kyushu University ) 

Research Interests 7

  1. Bioprocess

  2. Stem Cells

  3. Regenerative Medicine

  4. Cardiomyocyte

  5. Tissue Engineering

  6. Design of Experiments

  7. Bioengineering

Research Areas 1

  1. Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering

Current Research Project and SDGs 2

  1. Development of Stem Cell Differentiation Technologies for Regenerative Medicine and Drug Discovery

  2. Development of Cell Manufacturing Process for Regenerative Medicine

Research History 6

  1. Nagoya University   Assistant Professor

    2021.5

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    Country:Japan

  2. Revorf Co., Ltd.   Senior Scientist

    2020.5 - 2021.4

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    Country:Japan

  3. Kaneka Corporation   Assistant Manager

    2015.4 - 2020.4

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    Country:Japan

  4. University of Toronto   Institute of Biomaterials & Biomedical Engineering   Visiting Scientist

    2016.5 - 2018.4

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    Country:Canada

  5. Kaneka Corporation   Scientist

    2011.4 - 2015.3

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    Country:Japan

  6. Japan Society for Promotion of Science   Research Fellowship for Young Scientists (DC2)

    2009.4 - 2011.3

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    Country:Japan

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Education 3

  1. Kyushu University   Graduate School of Engineering   Chemical Systems and Engineering (Doctoral Course)

    2008.4 - 2011.3

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    Country: Japan

  2. Kyushu University   Graduate School of Engineering   Chemical Systems and Engineering (Master's Course)

    2007.4 - 2008.3

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    Country: Japan

  3. Kyushu University   Faculty of Engineering   Department of Materials Science and Engineering

    2003.4 - 2007.3

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    Country: Japan

Professional Memberships 3

  1. The Society of Chemical Engineers, Japan

  2. The Society for Biotechnology, Japan

  3. The Japanese Society for Regenerative Medicine

 

Papers 13

  1. Alignment of Skeletal Muscle Cells Facilitates Acetylcholine Receptor Clustering and Neuromuscular Junction Formation with Co-Cultured Human iPSC-Derived Motor Neurons Reviewed

    Kazunori Shimizu, Haruo Kassai, Yuhei Kamei, Kazuki Yamamoto, Takunori Nagashima, Tadayoshi Maekawa, Hirokazu Akiyama, Hiroyuki Honda

    Cells   Vol. 11 ( 23 ) page: 3760   2022.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/cells11233760

  2. Detection of protease digestion site using fluorescence labeled peptide array and construction of machine-learning prediction model Reviewed

    Ryota Mizutani, Yoko Mori, Shodai Ogawa, Kaho Tazoe, Hirokazu Akiyama, Kazunori Shimizu, Hiroyuki Honda

    Seibutsu-kogaku   Vol. 100 ( 10 ) page: 528 - 540   2022.10

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI: 10.34565/seibutsukogaku.100.10_528

    DOI: 10.34565/seibutsukogaku.100.10_528

  3. Screening of anti-atrophic peptides by using photo-cleavable peptide array and 96-well scale contractile human skeletal muscle atrophy models. Reviewed

    Yamamoto K, Ohsumi S, Nagashima T, Akiyama H, Honda H, Shimizu K

    Biotechnology and bioengineering     2022.4

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    Language:English  

    DOI: 10.1002/bit.28125

    PubMed

  4. Embryoid Body-Explant Outgrowth Cultivation from Induced Pluripotent Stem Cells in an Automated Closed Platform Reviewed

    Hiroshi Tone, Saeko Yoshioka, Hirokazu Akiyama, Akira Nishimura, Masaki Ichimura, Masaru Nakatani, Tohru Kiyono, Masashi Toyoda, Masatoshi Watanabe, Akihiro Umezawa

    BioMed Research International   Vol. 2016   page: 7098987   2016

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1155/2016/7098987

    DOI: 10.1155/2016/7098987

  5. Comparison of manual and automated cultures of bone marrow stromal cells for bone tissue engineering Reviewed

    Hirokazu Akiyama, Asako Kobayashi, Masaki Ichimura, Hiroshi Tone, Masaru Nakatani, Minoru Inoue, Arinobu Tojo, Hideaki Kagami

    Journal of Bioscience and Bioengineering   Vol. 120 ( 5 ) page: 570 - 576   2015.11

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.jbiosc.2015.03.011

    DOI: 10.1016/j.jbiosc.2015.03.011

  6. Effects of B-cell lymphoma 2 gene transfer to myoblast cells on skeletal muscle tissue formation using magnetic force-based tissue engineering Reviewed

    Masanori Sato, Akira Ito, Hirokazu Akiyama, Yoshinori Kawabe, Masamichi Kamihira

    Tissue Engineering Part A   Vol. 19 ( 1-2 ) page: 307 - 315   2013.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1089/ten.TEA.2011.0728

    DOI: 10.1089/ten.TEA.2011.0728

  7. Construction of cardiac tissue rings using a magnetic tissue fabrication technique Reviewed

    Hirokazu Akiyama, Akira Ito, Masanori Sato, Yoshinori Kawabe, Masamichi Kamihira

    International Journal of Molecular Sciences   Vol. 11 ( 8 ) page: 2910 - 2920   2010.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ijms11082910

    DOI: 10.3390/ijms11082910

  8. Cell-patterning using poly (ethylene glycol)-modified magnetite nanoparticles Reviewed

    Hirokazu Akiyama, Akira Ito, Masanori Sato, Yoshinori Kawabe, Masamichi Kamihira

    Journal of Biomedical Materials Research Part A   Vol. 92 ( 3 ) page: 1123 - 1130   2010.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/jbm.a.32313

    DOI: 10.1002/jbm.a.32313

  9. Genetically engineered angiogenic cell sheets using magnetic force-based gene delivery and tissue fabrication techniques Reviewed

    Hirokazu Akiyama, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira

    Biomaterials   Vol. 31 ( 6 ) page: 1251 - 1259   2010.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.biomaterials.2009.11.017

    DOI: 10.1016/j.biomaterials.2009.11.017

  10. Fabrication of angiogenic gene-modified myoblast cell sheets using magnetic tissue engineering techniques.

    Hirokazu Akiyama, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira

    Proceedings of the World Congress on Engineering and Computer Science   Vol. 2   page: 806 - 810   2010

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    Authorship:Lead author   Language:English   Publishing type:Research paper (international conference proceedings)  

  11. Magnetic cell-patterning for tissue engineering

    Hirokazu Akiyama, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira

    Animal Cell Technology: Basic & Applied Aspects (Proceedings of JAACT2008)   Vol. 16   page: 165 - 170   2010

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    Authorship:Lead author   Language:English   Publishing type:Research paper (international conference proceedings)  

    DOI: 10.1007/978-90-481-3892-0_27

  12. Fabrication of complex three-dimensional tissue architectures using a magnetic force-based cell patterning technique Reviewed

    Hirokazu Akiyama, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira

    Biomedical Microdevices   Vol. 11 ( 4 ) page: 713 - 721   2009.8

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s10544-009-9284-x

    DOI: 10.1007/s10544-009-9284-x

  13. Magnetic force-based cell patterning using Arg-Gly-Asp (RGD) peptide-conjugated magnetite cationic liposomes Reviewed

    Akira Ito, Hirokazu Akiyama, Yoshinori Kawabe, Masamichi Kamihira

    Journal of Bioscience and Bioengineering   Vol. 104 ( 4 ) page: 288 - 293   2007.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1263/jbb.104.288

    DOI: 10.1263/jbb.104.288

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Books 2

  1. 三次元ティッシュエンジニア リング~細胞の培養・操作・組織化から品質管理、脱細胞化まで~・間葉系幹細胞向け自動培養装置(4章2節)

    刀禰宏、秋山裕和( Role: Joint author)

    エヌ・ティー・エス  2015 

  2. ≪最 新≫動物細胞培養の手法と細胞死・増殖不良・細胞変異を防止する技術・閉鎖型自動培養装置による間葉系幹細胞の培養(2章4節12項)

    秋山裕和、櫻井裕士( Role: Joint author)

    技術情報協会  2014 

Research Project for Joint Research, Competitive Funding, etc. 4

  1. Development of Cardiomyocyte/Epicardial Cell Co-differentiation Process from Pluripotent Stem Cells for Next-generation Regenerative Medicine

    2022.12 - 2023.11

    The Public Foundation of Chubu Science and Technology Center  Academic / Mirai Grant 

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\300000

  2. Development of Simultaneous Generation Process of Cardiac Muscle Tissue Cells from Pluripotent Stem Cells

    2022.5 - 2023.4

    The Naito Science & Engineering Foundation  The Naito Research Grant 

    Hirokazu Akiyama

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000

  3. 臍帯血造血幹細胞の培養プロセスの開発

    2016.5 - 2018.4

    カネカ 技術振興基金(海外留学) 

    秋山裕和

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    Authorship:Principal investigator  Grant type:Other

    Grant amount:\4000000

  4. Fabrication of angiogenic gene-modified myoblast cell sheets using magnetic tissue engineering techniques

    2010.10

    Kato Memorial Bioscience Foundation  The Kato Memorial Bioscience Grant for International Research Fellowship 

    Hirokazu Akiyama

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\200000

KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. 可食性タンパク質由来の非劣性中長鎖生理活性ペプチドの効率的探索法の確立

    Grant number:22H00273  2022.4 - 2026.3

    日本学術振興会  科学研究費補助金  基盤研究(A)

    本多裕之, 秋山裕和, 清水一憲

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  2. メカニカルストレス制御による革新的オルガノイド形成プロセスの理解深化と応用展開

    Grant number:21K19899  2021.7 - 2023.3

    日本学術振興会  科学研究費補助金  挑戦的研究(萌芽)

    清水一憲, 秋山裕和

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    Authorship:Coinvestigator(s)  Grant type:Competitive

  3. 磁性ナノ粒子を用いた血管配置及び誘導による骨格筋組織再生

    Grant number:09J02784  2009.4 - 2011.3

    日本学術振興会  科学研究費補助金  特別研究員奨励費(DC2)

    秋山裕和

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1400000

 

Teaching Experience (On-campus) 5

  1. Chemistry/Biochemistry Laboratory III

    2022

  2. Chemistry/Biochemistry Laboratory II

    2022

  3. Chemistry/Biochemistry Laboratory III

    2021

  4. Chemistry/Biochemistry Laboratory II

    2021

  5. 卒業研究

    2021