Updated on 2025/03/25

写真a

 
MORI Shoichiro
 
Organization
Nagoya University Hospital Dermatology Assistant Professor
Title
Assistant Professor

Degree 2

  1. 学士(医学） （ 2013.4   名古屋大学 ） 

  2. 学士 （ 名古屋大学 ） 

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Research History 1

  1. Nagoya University   Assistant professor of hospital

    2021.4

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Education 1

  1. Nagoya University

    2007.4 - 2013.3

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Professional Memberships 1

  1. 日本皮膚科学会

    2015.4

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Awards 1

  1. ポスター賞

    2023.8   皮膚悪性腫瘍学会   悪性黒色腫に対する抗PD1抗体単独療法での、１回投与量／投与間隔が異なるレジメンと有害事象の相関の検討

    森　章一郎

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    Award type：Award from Japanese society, conference, symposium, etc. 

    第39回日本皮膚悪性腫瘍学会学術大会のポスター賞

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Papers 15

  1. Infiltration of M2a macrophages is predominant in genital verruciform xanthoma Open Access

    Miyazaki, A; Taki, T; Mori, S; Yamada, M; Akiyama, M

    JOURNAL OF DERMATOLOGY   Vol. 52 ( 3 ) page： 556 - 558   2025.3

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    Language：English   Publisher：Journal of Dermatology  

    DOI： 10.1111/1346-8138.17654

    Open Access

    Web of Science

    Scopus

    PubMed

  2. Combined PD-1 and CTLA-4 Blockade Increases the Risks of Multiple Pituitary Hormone Deficiency and Isolated Adrenocorticotropic Deficiency: A Prospective Study.

    Iwama S, Kobayashi T, Izuchi T, Suzuki K, Murase T, Ando M, Handa T, Onoue T, Miyata T, Sugiyama M, Hagiwara D, Suga H, Banno R, Hase T, Mori S, Sano T, Akamatsu S, Akiyama M, Ishii M, Arima H

    Endocrinology and metabolism (Seoul, Korea)     2025.2

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    Language：English  

    DOI： 10.3803/EnM.2024.2180

    PubMed

  3. Prognostic value of the CONUT score with immune checkpoint inhibitors as first-line therapy for metastatic malignant melanoma

    Horisaki, K; Yoshikawa, S; Mori, S; Omata, W; Tsutsumida, A; Kiyohara, Y

    JOURNAL OF DERMATOLOGY     2025.2

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    Language：English   Publisher：Journal of Dermatology  

    The recent availability of immune checkpoint inhibitors (ICIs) has revolutionized the treatment of advanced malignant melanoma (MM). However, many patients with MM do not benefit from ICI treatment. As immunotherapy is associated with significant toxicity and high treatment costs despite its excellent efficacy, it is pertinent to select patients who are likely to respond to ICIs. In this single-center, retrospective study we investigated whether the controlling nutritional status (CONUT) score is a useful prognostic marker in Japanese patients with advanced-stage cancer. We analyzed 123 patients with stage IV MM treated with ICIs as first-line systemic treatment at our hospital between February 2012 and July 2024. Receiver operating characteristic curve analysis was used to calculate the CONUT cut-off value and CONUT into two groups of ≥3 and ≤2. Progression-free survival (PFS) and overall survival (OS) were determined using the Kaplan–Meier method, and differences in survival were assessed using the log-rank test. The Cox proportional hazard regression model was used to evaluate independent prognostic factors. Objective response rate (ORR), PFS, and OS were significantly low in the CONUT ≥3 group, characterized by low nutritional status and high inflammation. Multivariate analysis identified the CONUT score as an independent prognostic factor for both PFS and OS. The CONUT score was not significantly associated with the development of serious immune-related adverse events. The simplicity of the CONUT score may aid in identifying patients with MM who are suitable candidates for ICI treatment.

    DOI： 10.1111/1346-8138.17613

    Web of Science

    Scopus

    PubMed

  4. Protruding nodular fasciitis on the face

    Akanabe, H; Tanahashi, K; Mori, S; Murakami, Y; Motoi, T; Akiyama, M

    JOURNAL OF DERMATOLOGY     2024.12

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    Language：English   Publisher：Journal of Dermatology  

    DOI： 10.1111/1346-8138.17591

    Web of Science

    Scopus

    PubMed

  5. A Case of Advanced Extramammary Paget's Disease With a High Tumor Mutation Burden That Showed Partial Lymph Node Regression With Pembrolizumab.

    Horisaki K, Taki T, Mori S, Okumura M, Akiyama M

    Cureus   Vol. 16 ( 10 ) page： e72592   2024.10

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    Language：English  

    DOI： 10.7759/cureus.72592

    PubMed

  6. Combined use of tyrosine kinase inhibitors with PD-(L)1 blockade increased the risk of thyroid dysfunction in PD-(L)1 blockade: a prospective study Open Access

    Kobayashi, T; Iwama, S; Yamagami, A; Izuchi, T; Suzuki, K; Otake, K; Yasuda, Y; Ando, M; Onoue, T; Miyata, T; Sugiyama, M; Hagiwara, D; Suga, H; Banno, R; Hase, T; Nishio, N; Mori, S; Shimokata, T; Sano, T; Niimi, K; Yoshikawa, N; Akamatsu, S; Ando, Y; Akiyama, M; Sone, M; Ishii, M; Arima, H

    CANCER IMMUNOLOGY IMMUNOTHERAPY   Vol. 73 ( 8 ) page： 146   2024.6

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    Language：English   Publisher：Cancer Immunology, Immunotherapy  

    Background: Anti-programmed cell death-1 (ligand-1) antibody [PD-(L)1-Ab] can cause destructive thyroiditis and/or hypothyroidism. In addition, tyrosine kinase inhibitors (TKIs) frequently induce hypothyroidism. The aim of this prospective study is to examine the incidence and clinical characteristics of thyroid dysfunction induced by combination therapy of a PD-(L)1-Ab and TKI [PD-(L)1-Ab/TKI]. Methods: A total of 757 patients treated with PD-(L)1-Ab or PD-(L)1-Ab/TKI were evaluated for anti-thyroid antibodies (ATAs) at baseline and for thyroid function for 48 weeks after treatment initiation and then observed until the last visit. Results: The cumulative incidences of destructive thyroiditis [4/23 (17.4%) vs. 45/734 (6.1%) patients, p < 0.001], isolated hypothyroidism [10/23 (43.5%) vs. 29/734 (4.0%) patients, p < 0.001], and all thyroid dysfunction [14/23 (60.9%) vs. 74/734 (10.1%) patients, p < 0.001] were significantly higher in the PD-(L)1-Ab/TKI group than PD-(L)1-Ab group, respectively. All patients positive for ATAs at baseline developed thyroid dysfunction after PD-(L)1-Ab/TKI treatment, a significantly higher incidence than that in those negative for ATAs at baseline [4/4 (100%) vs. 10/19 (52.6%) patients, p = 0.026]. Conclusions: The addition of TKIs increased the risk of thyroid dysfunction induced by PD-(L)1-Ab, with the risk being higher in patients positive for baseline ATAs.

    DOI： 10.1007/s00262-024-03733-2

    Open Access

    Web of Science

    Scopus

    PubMed

  7. Lentigo maligna melanoma showing radial growth mimicking eruptive melanocytic nevi Open Access

    Miyazaki, A; Taki, T; Mori, S; Yamada, M; Akiyama, M

    DERMATOLOGICA SINICA   Vol. 42 ( 2 ) page： 162 - 163   2024.4

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  8. Acquired reactive perforating collagenosis and eosinophilic granulomatosis with polyangiitis developing simultaneously in a diabetic patient

    Miyazaki, A; Taki, T; Mori, S; Fujishiro, R; Arai, Y; Yamada, M; Akiyama, M

    JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY   Vol. 7   2024.2

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  9. 特集 毛包系腫瘍 臨床例 FDG-PET/CTで両腋窩リンパ節に偽陽性を示した増殖性外毛根鞘性腫瘍

    森 章一郎, 山田 元人

    皮膚病診療   Vol. 46 ( 2 ) page： 177 - 181   2024.2

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    Publisher：協和企画  

    DOI： 10.24733/pd.0000003735

    CiNii Research

  10. Low plasma fibrinogen levels are associated with poor prognosis in cutaneous angiosarcoma of the head and neck

    Taki, T; Mori, S; Murakami, Y; Urata, T; Okumura, M; Akanabe, H; Ebata, A; Imai, S; Yokota, K; Akiyama, M

    JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 142 ( 12 ) page： S265 - S265   2022.12

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  11. A case of parietal DFSP with difficulty in determining the resection margin

    AKANABE Honami, MORI Shoichiro, OKUMURA Mao, URATA Toru, MURAKAMI Yoshie, YOKOTA Kenji, AKIYAMA Masashi, TANAHASHI Kuniaki, EBISAWA Katsumi, MORI Takako

    Skin Cancer   Vol. 37 ( 3 ) page： 213 - 217   2022

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    Language：Japanese   Publisher：The Japanese Skin Cancer Society  

    <p>A 20－year－old male noticed a skin nodule on his scalp, which gradually increased in size. At his first visit, a 5×3 cm elevated reddish nodule with poor mobility was found over the parietal region. A skin biopsy showed spindle－shaped cell proliferation, CD34 positivity, <i>COL1A1－PDGFB</i> fusion gene. The tumor was diagnosed as dermatofibrosarcoma protuberans with fibrosarcomatous changes. CT and MRI showed a subcutaneous nodule near the skin nodule, and suspected periosteal invasion. Mapping biopsy was done with a margin of 20 mm around the lesion, and one site was positive. Another biopsy was done 10 mm away from the positive site ; this was also reported positive. A further biopsy done 10 mm away from the site was finally negative. A resection operation was performed. Resection margins were negative and there was no recurrence. Mapping biopsy may be useful in determining the extent of resection for dermatofibrosarcoma protuberans of the scalp.[<i>Skin Cancer (Japan)</i> 2022 ; 37 : 213－217]</p>

    DOI： 10.5227/skincancer.37.213

    CiNii Research

  12. Neutrophil/lymphocyte ratio as a predictor of lymph node metastasis in extramammary Paget disease: A retrospective study

    Ebata, A; Taki, T; Mori, S; Murakami, Y; Urata, T; Okumura, M; Akanabe, H; Imai, S; Yokota, K; Akiyama, M

    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY   Vol. 85 ( 4 ) page： 1023 - 1025   2021.10

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    Language：English   Publisher：Journal of the American Academy of Dermatology  

    DOI： 10.1016/j.jaad.2020.12.087

    Web of Science

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  13. Neutrophil/lymphocyte ratio as a predictor of lymph node metastasis in extramammary Paget disease: A retrospective study

    Ebata, A; Taki, T; Mori, S; Murakami, Y; Okumura, M; Akanabe, H; Imai, S; Yokota, K; Akiyama, M

    JOURNAL OF INVESTIGATIVE DERMATOLOGY   Vol. 141 ( 10 ) page： S197 - S197   2021.10

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  14. Low plasma fibrinogen levels are associated with poor prognosis in cutaneous angiosarcoma of the head and neck Open Access

    Mori, S; Taki, T; Murakami, Y; Urata, T; Okumura, M; Akanabe, H; Ebata, A; Imai, S; Yokota, K; Akiyama, M

    CANCER SCIENCE   Vol. 112 ( 9 ) page： 3924 - 3927   2021.9

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    Language：English   Publisher：Cancer Science  

    DOI： 10.1111/cas.15037

    Web of Science

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  15. Cutaneous malignant melanoma in an elderly patient with intermediate junctional epidermolysis bullosa

    Yamashita, Y; Taki, T; Takeichi, T; Okumura, M; Mori, S; Ito, Y; Ogi, T; Yamada, M; Akiyama, M

    JOURNAL OF DERMATOLOGY   Vol. 48 ( 8 ) page： E384 - E385   2021.8

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    Language：English   Publisher：Journal of Dermatology  

    DOI： 10.1111/1346-8138.15951

    Web of Science

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