Updated on 2024/03/22
博士（医学） （ 2021.3 名古屋大学 ）
Life Science / Hygiene and public health (laboratory) / 腸内細菌、統計学、機械学習、ゲノム解析
Calcitriol ameliorates motor deficits and prolongs survival of Chrne-deficient mouse, a model for congenital myasthenic syndrome, by inducing Rspo2 Reviewed
Bisei Ohkawara, Hiroyuki Tomita, Taro Inoue, Shaochuan Zhang, Shunsuke Kanbara, Hiroyuki Koshimizu, Yuki Miyasaka, Jun-Ichi Takeda, Hiroshi Nishiwaki, Hiroaki Nakashima, Mikako Ito, Akio Masuda, Naoki Ishiguro, Tomoo Ogi, Tamio Ohno, Shiro Imagama, Kinji Ohno
Neurotherapeutics Vol. 21 ( 2 ) page： e00318 2024.1
Development of machine learning models for predicting unfavorable functional outcomes from preoperative data in patients with chronic subdural hematomas Reviewed
Yutaro Fuse, Yoshitaka Nagashima, Hiroshi Nishiwaki, Fumiharu Ohka, Yusuke Muramatsu, Yoshio Araki, Yusuke Nishimura, Jumpei Ienaga, Tetsuya Nagatani, Yukio Seki, Kazuhiko Watanabe, Kinji Ohno, Ryuta Saito
Scientific reports Vol. 13 ( 1 ) page： 16997 - 16997 2023.10
Gastrointestinal disorders in Parkinson's disease and other Lewy body diseases. Reviewed
Hirayama M, Nishiwaki H, Hamaguchi T, Ohno K
NPJ Parkinson's disease Vol. 9 ( 1 ) page： 71 2023.5
Fuse Yutaro, Takeuchi Kazuhito, Nishiwaki Hiroshi, Imaizumi Takahiro, Nagata Yuichi, Ohno Kinji, Saito Ryuta
PITUITARY 2023.3
Effects of Pesticide Intake on Gut Microbiota and Metabolites in Healthy Adults Reviewed
Ueyama Jun, Hayashi Mai, Hirayama Masaaki, Nishiwaki Hiroshi, Ito Mikako, Saito Isao, Tsuboi Yoshio, Isobe Tomohiko, Ohno Kinji
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH Vol. 20 ( 1 ) 2023.1
Gut microbiota in dementia with Lewy bodies Reviewed
Nishiwaki H., Ueyama J., Kashihara K., Ito M., Hamaguchi T., Maeda T., Tsuboi Y., Katsuno M., Hirayama M., Ohno K.
npj Parkinson's Disease Vol. 8 ( 1 ) page： 169 2022.12
Short chain fatty acids-producing and mucin-degrading intestinal bacteria predict the progression of early Parkinson's disease. Reviewed
Nishiwaki H, Ito M, Hamaguchi T, Maeda T, Kashihara K, Tsuboi Y, Ueyama J, Yoshida T, Hanada H, Takeuchi I, Katsuno M, Hirayama M, Ohno K
NPJ Parkinson's disease Vol. 8 ( 1 ) page： 65 2022.6
Hasegawa Tomoya, Ito Mikako, Hasegawa Satoru, Teranishi Masaki, Takeda Koki, Negishi Shuto, Nishiwaki Hiroshi, Takeda Jun-ichi, LeBaron Tyler W., Ohno Kinji
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol. 23 ( 5 ) 2022.3
Altered gut microbiota in Parkinson's disease patients with motor complications Reviewed
Takahashi Kai, Nishiwaki Hiroshi, Ito Mikako, Iwaoka Kazuhiro, Takahashi Kenta, Suzuki Yoshio, Taguchi Keita, Yamahara Kanako, Tsuboi Yoshio, Kashihara Kenichi, Hirayama Masaaki, Ohno Kinji, Maeda Tetsuya
PARKINSONISM & RELATED DISORDERS Vol. 95 page： 11 - 17 2022.2
Hirayama Masaaki, Nishiwaki Hiroshi, Hamaguchi Tomonari, Ito Mikako, Ueyama Jun, Maeda Tetsuya, Kashihara Kenichi, Tsuboi Yoshio, Ohno Kinji
PLOS ONE Vol. 16 ( 11 ) page： e0260451 2021.11
Short-Chain Fatty Acid-Producing Gut Microbiota Is Decreased in Parkinson's Disease but Not in Rapid-Eye-Movement Sleep Behavior Disorder Reviewed
Hiroshi Nishiwaki, Tomonari Hamaguchi, Mikako Ito, Tomohiro Ishida, Tetsuya Maeda, Kenichi Kashihara, Yoshio Tsuboi, Jun Ueyama, Teppei Shimamura, Hiroshi Mori, Ken Kurokawa, Masahisa Katsuno, Masaaki Hirayama, Kinji Ohno
mSystems 2020.12
Meta-Analysis of Gut Dysbiosis in Parkinson's Disease Reviewed
Hiroshi Nishiwaki,Mikako Ito,Tomohiro Ishida,Tomonari Hamaguchi,Tetsuya Maeda,Kenichi Kashihara,Yoshio Tsuboi,Jun Ueyama,Teppei Shimamura,Hiroshi Mori,Ken Kurokawa,Masahisa Katsuno,Masaaki Hirayama,Kinji Ohno
Movement Disorders 2020.6
Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles: meta-analyses of gene expression profiles Reviewed
Hiroshi Nishiwaki, Mikako Ito, Shuto Negishi, Sayaka Sobue, Masatoshi Ichihara, Kinji Ohno
Free Radical Research 2018.3
Mechanism of Anomalous Tunneling in Condensed Bose System Reviewed
Yusuke Kato, Hiroshi Nishiwaki, and Akitake Fujita
J. Phys. Soc. Jpn. 2007.11
Gut dysbiosis dysregulating short chain fatty acids and mucosal barrier in dementia with Lewy bodies International conference
H. Nishiwaki, M. Ito, T. Hamaguchi, K. Kashihara, T. Maeda, Y. Tsuboi, M. Katsuno, M. Hirayama, K. Ohno
The 9th International Human Microbiome Consortium (IHMC) Congress 2022 2022.11.8
Gut dysbiosis in patients with dementia with Lewy bodies International conference
H. Nishiwaki, M. Ito, T. Hamaguchi, K. Kashihara, T. Maeda, Y. Tsuboi, M. Katsuno, M. Hirayama, K. Ohno
the 2022 MDS International Congress (On line) 2022.9.15
Hydrogen producing enzymes in Parkinson’s disease patients Invited
2022.9.7
GUT MICROBIOTA PREDICTS THE PROGRESSION OF EARLY PARKINSON'S DISEASE. International conference
Hiroshi Nishiwaki
Targeting Microbiota 2021 (On line) 2021.10.20
Gut microbiota in patients with Parkinson’s disease (PD) predicts disease progression better than clinical features. International conference
H. Nishiwaki, M. Ito, T. Hamaguchi, T. Maeda, K. Kashihara, Y. Tsuboi, M. Masahisa, M. Hirayama, K. Ohno
MDS Virtual Congress 2021 2021.9.17
パーキンソン病患者の腸内細菌叢異常のメタ分析と予後因子
西脇寛、伊藤美佳子、石田智大、浜口知成、前田哲也、柏原健一、坪井義夫、上山純、島村鉄平、森宙史、黒川顕、平山正明、大野欽司
第25回腸内細菌学会学術集会（誌上開催）
Cross-platform-analysis and meta-analysis of gene expression profiles reveal pathways modulated by molecular hydrogen
2017.10.29
Meta-analysis of gene expression profiles for dissecting molecular mechanisms of hydrogen
2016.5.28
Grant number：22K17343 2022.4 - 2024.3
科学研究費助成事業 若手研究
西脇 寛
Authorship：Principal investigator
Grant amount：\4680000 （ Direct Cost: \3600000 、 Indirect Cost：\1080000 ）
腸内細菌叢に占めるコリンセラ属の情報を提供する方法、当該情報を用いたＣＯＶＩＤ−１９重症化予測方法およびサイトカインストーム重症化予測方
