Updated on 2025/04/04

写真a

 
NAGAYOSHI Mako
 
Organization
Graduate School of Medicine Program in Integrated Medicine Social Life Science Lecturer
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine Department of Medicine
Title
Lecturer
External link

Degree 1

  1. 博士(医学) ( 2012.3   大阪大学 ) 

Research Interests 19

  1. Epidemiology

  2. Social Network

  3. Social Suport

  4. 父親支援

  5. Diabetes

  6. Cardiovascular disease

  7. Oral frail

  8. Cancer

  9. Sleep disordered breathing

  10. 生きづらさ

  11. 介護予防

  12. precarious employment

  13. Oral frailty

  14. Cardiovascular disease

  15. Epidemiology

  16. Sleep disordered breathing

  17. job insecurity

  18. Social network

  19. Social support

Research Areas 2

  1. Life Science / Hygiene and public health (laboratory)

  2. Life Science / Hygiene and public health (non-laboratory)

Current Research Project and SDGs 6

  1. 不安定雇用・雇用不安と次世代の健康・成育環境との関連とその緩衝要因に関する研究

  2. 父親支援と家族の健康・子どもの成育環境との関連に関する研究

  3. ソーシャルネットワークの健康影響に関する地域疫学研究

  4. 生活習慣と遺伝要因の疾患リスク解明のための地域疫学研究

  5. 心理的要因の健康影響解明のための疫学研究

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Research History 11

  1. Nagoya University   Graduate School of Medicine   Lecturer

    2024.1

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    Country:Japan

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  2. Nagoya University   Department of Preventive Medicine   Assistant Professor

    2021.11

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    Country:Japan

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  3. Nagoya University   Graduate School of Medicine   Designated Assistant Professor

    2020.4 - 2021.11

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  4. University of Minnesota School of Public Health   Division of Epidemiology and Community Health   Researcher

    2012.11 - 2013.11

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    Country:United States

  5. Osaka University   Department of Medicine   Researcher

    2012.5 - 2013.3

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    Country:Japan

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Education 3

  1. Osaka University   Department of Medicine

    2008.4 - 2012.3

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    Country: Japan

  2. University of Tsukuba   Department of Medical Science

    2006.4 - 2008.3

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    Country: Japan

  3. Kobe University

    1999.4 - 2003.3

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    Country: Japan

Professional Memberships 5

  1. Japan Epidemiological Association

    2009.5

  2. Japan Society of Public Health

    2008.9

  3. American Heart Association

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  4. JAPAN EPIDEMIOLOGICAL ASSOCIATION

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  5. JAPANESE SOCIETY OF PUBLIC HEALTH

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Committee Memberships 12

  1. 日本疫学会   代議員  

    2019.6   

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    Committee type:Academic society

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  2. 日本公衆衛生学会   代議員  

    2017.6   

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    Committee type:Academic society

    任期:2017年6月~2019年5月、2021年7月~現在

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  3. Japan Young Association   Organizer  

    2018.4   

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    Committee type:Other

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  4. 日本医学会連合   第3回社会部会リトリート企画委員会 若手企画委員  

    2024.4   

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    Committee type:Academic society

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  5. 名古屋大学 アカデミックフラッシュ   実行委員  

    2021.4   

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    Committee type:Other

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Awards 2

  1. American Heart Association Scientific Session 2014 The New Investigator Travel Award

    2014.3   American Heart Association  

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    Award type:Award from international society, conference, symposium, etc.  Country:United States

  2. 第75回 日本公衆衛生学会 口頭賞

    2016.10   日本公衆衛生学会  

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    Award type:Award from Japanese society, conference, symposium, etc. 

 

Papers 83

  1. Paternal involvement in childcare and housework and mothers' spanking behavior: The Japanese longitudinal survey of newborns in the 21st century. Reviewed

    Mako Nagayoshi, Yuko Kachi, Tsuguhiko Kato, Manami Ochi, Yuichi Ichinose, Takayuki Kondo, Kenji Takehara

    Journal of epidemiology   Vol. 34 ( 12 ) page: 577 - 586   2024.12

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japan Epidemiological Association  

    BACKGROUND: No previous study reported an association between paternal involvement in childcare and housework and maternal physical punishment. METHODS: Using data from the Japanese Longitudinal Survey of Newborns in the 21st century (N = 38,554), we analyzed responses about fathers' involvement in childcare and housework at 6 months and mothers' spanking of children at 3.5 years. Fathers' involvement in childcare and housework was scored and categorized into quartiles. Spanking frequency was asked in the "often", "sometimes", or "not at all" categories. Multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the mothers' often spanking children were computed for the fathers' involvement in childcare and housework. We also stratified the association by fathers' working hours (40-49, 50-59, or ≥ 60 hours/week). RESULTS: Among the 16,373 respondents, the proportion of mothers who often spanked their children was 4.8%. Compared with the lowest quartile, a higher frequency of paternal involvement in housework was associated with a lower risk of spanking children (p trend = 0.001). Adjustment for covariates attenuated the association, but significant association was observed in the 3rd quartile of paternal involvement in housework [OR (95% CI): 0.77 (0.62-0.96)]. When the fathers worked fewer than 50 hours a week, a significant negative association was observed between the fathers' frequency of childcare and the likeliness of the mothers' spanking their children (p trend = 0.02). CONCLUSIONS: The fathers' active involvement in childcare and housework could reduce the mothers' physical punishment for their children.

    DOI: 10.2188/jea.JE20230270

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  2. Response to the Letter Regarding "Paternal involvement in childcare and housework and mothers' spanking behavior: The Japanese longitudinal survey of newborns in the 21st century". Invited Reviewed

    Mako Nagayoshi, Yuko Kachi, Tsuguhiko Kato, Manami Ochi, Yuichi Ichinose, Takayuki Kondo, Kenji Takehara

    Journal of epidemiology   Vol. advpub ( 0 )   2024.3

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japan Epidemiological Association  

    DOI: 10.2188/jea.JE20240433

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  3. BMI and cardiometabolic traits in Japanese: a Mendelian randomization study. Invited Reviewed International journal

    Mako Nagayoshi, Asahi Hishida, Tomonori Shimizu, Yasufumi Kato, Yoko Kubo, Rieko Okada, Takashi Tamura, Jun Otonari, Hiroaki Ikezaki, Megumi Hara, Yuichiro Nishida, Isao Oze, Yuriko N Koyanagi, Yohko Nakamura, Miho Kusakabe, Rie Ibusuki, Keiichi Shibuya, Sadao Suzuki, Takeshi Nishiyama, Teruhide Koyama, Etsuko Ozaki, Kiyonori Kuriki, Naoyuki Takashima, Yasuyuki Nakamura, Sakurako Katsuura-Kamano, Kokichi Arisawa, Masahiro Nakatochi, Yukihide Momozawa, Kenji Takeuchi, Kenji Wakai

    Journal of epidemiology   Vol. 34 ( 2 ) page: 51 - 62   2024.2

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japan Epidemiological Association  

    BACKGROUND: Although many observational studies have demonstrated significant relationships between obesity and cardiometabolic traits, the causality of these relationships in East Asians remains to be elucidated. METHODS: We conducted individual-level Mendelian randomization (MR) analyses targeting 14,083 participants in the Japan Multi-Institutional Collaborative Cohort Study, and two-sample MR analyses using summary statistics based on genome-wide association study data from 173,430 Japanese. Using 83 body mass index-related loci, genetic risk scores (GRS) for BMI were calculated, and the effects of BMI on cardiometabolic traits were examined for individual-level MR analyses by the two-stage least squares estimator method. The β-coefficients and standard errors for the per-allele association of each single-nucleotide polymorphism as well as all outcomes, or odds ratios with 95% confidence intervals were calculated in the two-sample MR analyses. RESULTS: In individual-level MR analyses, the GRS of BMI was not significantly associated with any cardiometabolic traits. In two-sample MR analyses, higher BMI was associated with higher risks of higher blood pressure, triglycerides, uric acid, lower high-density-lipoprotein cholesterol and eGFR. The associations of BMI with type 2 diabetes in two-sample MR analyses were inconsistent by different methods, including the directions. CONCLUSIONS: The results of this study suggest that, even among the Japanese, an East Asian population with low levels of obesity, higher BMI could be causally associated with the development of a variety of cardiometabolic traits. Causality in those associations should be clarified in future studies with larger populations, especially those of BMI with type 2 diabetes.

    DOI: 10.2188/jea.JE20220154

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  4. Sex-specific Relationship between Stress Coping Strategies and All-Cause Mortality: Japan Multi-Institutional Collaborative Cohort Study Invited Reviewed

    Mako Nagayoshi, Kenji Takeuchi, Yudai Tamada, Kato Yasufumi, Yoko Kubo, Rieko Okada, Takashi Tamura, Asahi Hishida, Jun Otonari, Hiroaki Ikezaki, Yuichiro Nishida, Chisato Shimanoe, Yuriko N. Koyanagi, Keitaro Matsuo, Mikami Haruo, Kusakabe Miho, Daisaku Nishimoto, Keiichi Shibuya, Sadao Suzuki, Takeshi Nishiyama, Etsuko Ozaki, Isao Watanabe, Kiyonori Kuriki, Naoyuki Takashima, Aya Kadota, Kokichi Arisawa, Sakurako Katsuura-Kamano, Kenji Wakai

    Journal of Epidemiology   Vol. 33 ( 5 ) page: 236 - 245   2023.5

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    Authorship:Lead author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Japan Epidemiological Association  

    BACKGROUND: Stress coping strategies are related to health outcomes. However, there is no clear evidence for sex differences between stress-coping strategies and mortality. We investigated the relationship between all-cause mortality and stress-coping strategies, focusing on sex differences among Japanese adults. METHODS: A total of 79,580 individuals aged 35-69 years participated in the Japan Multi-Institutional Collaborative Cohort Study between 2004 and 2014 and were followed up for mortality. The frequency of use of the five coping strategies was assessed using a questionnaire. Sex-specific, multivariable-adjusted hazard ratios (HRs) for using each coping strategy ("sometimes," and "often/very often" use versus "very few" use) were computed for all-cause mortality. Furthermore, relationships were analyzed in specific follow-up periods when the proportion assumption was violated. RESULTS: During the follow-up (median: 8.5 years), 1,861 mortalities were recorded. In women, three coping strategies were related to lower total mortality. The HRs for "sometimes" were 0.81 (95% confidence interval [CI], 0.67-0.97) for emotional expression, 0.79 (95% CI, 0.66-0.95) for emotional support-seeking, and 0.80 (95% CI, 0.66-0.98) for disengagement. Men who "sometimes" used emotional expression and sometimes or often used problem-solving and positive reappraisal had a 15-41% lower HRs for all-cause mortality. However, those relationships were dependent on the follow-up period. There was evidence that sex modified the relationships between emotional support-seeking and all-cause mortality (P for interaction = 0.03). CONCLUSION: In a large Japanese sample, selected coping strategies were associated with all-cause mortality. The relationship of emotional support-seeking was different between men and women.

    DOI: 10.2188/jea.JE20210220

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  5. Obstructive sleep apnea and incident type 2 diabetes Reviewed International coauthorship

    Mako Nagayoshi, Naresh M Punjabi, Elizabeth Selvin, James S Pankow, Eyal Shahar, Hiroyasu Iso, Aaron R Folsom, Pamela L Lutsey

    Sleep medicine   Vol. 25   page: 156 - 161   2016.9

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    Authorship:Lead author, Corresponding author  

    DOI: 10.1016/j.sleep.2016.05.009

    DOI: 10.1016/j.sleep.2016.05.009

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MISC 22

  1. The relationship between fathers' non-participation in childcare and subsequent divorce: the 21st Century Birth Cohort Study

    Journal of Epidemiology   Vol. 33 ( Suppl.1 ) page: 134   2023.2

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    Language:Japanese   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)  

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  2. 日本人中高年における食物摂取頻度調査票の妥当性の検討-利用可能炭水化物

    篠壁多恵, 今枝奈保美, 今枝奈保美, 後藤千穂, 後藤千穂, 中村洋子, 尾瀬功, 細野晃弘, 永吉真子, 宮川尚子, 宮川尚子, 尾崎悦子, 池崎裕昭, 南里妃名子, 指宿りえ, 釜野桜子, 栗木清典, 栗原綾子, 矢口友理

    日本疫学会学術総会講演集(Web)   Vol. 33rd   2023

  3. 日本人中高年における食物摂取頻度調査票の妥当性の検討-八訂成分表の食物繊維

    今枝奈保美, 篠壁多恵, 後藤千穂, 後藤千穂, 中村洋子, 尾瀬功, 細野晃弘, 永吉真子, 宮川尚子, 宮川尚子, 尾崎悦子, 池崎裕昭, 南里妃名子, 指宿りえ, 釜野桜子, 栗木清典, 栗原綾子, 矢口友理

    日本疫学会学術総会講演集(Web)   Vol. 33rd   2023

  4. 食物繊維摂取と大腸がん罹患との関連:J-MICC Study

    若井建志, 田村高志, 今枝奈保美, 今枝奈保美, 後藤千穂, 後藤千穂, 玉田雄大, 玉田雄大, 加藤泰文, 久保陽子, 岡田理恵子, 永吉真子, 菱田朝陽, 松尾恵太郎, 松尾恵太郎

    日本疫学会学術総会講演集(Web)   Vol. 33rd   2023

  5. 地域在住成人における食品群摂取量と高感度CRPとの関連の横断的検討

    松永貴史, 今枝奈保美, 今枝奈保美, 後藤千穂, 後藤千穂, 玉田雄大, 加藤泰文, 久保陽子, 岡田理恵子, 永吉真子, 田村高志, 菱田朝陽, 竹内研時, 若井建志

    日本疫学会学術総会講演集(Web)   Vol. 32nd   2022

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Presentations 60

  1. Causal Relationship between BMI and Cardiovascular and Metabolic Diseases in Japanese assessed by Mendelian Randomized Analysis Invited

    Mako Nagayoshi

    Session 8 Genetic Statistics in Genomic Cohort Studies Seminar  2023.8.24 

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    Event date: 2023.8

    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:Saga   Country:Japan  

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  2. 父親の家事・育児頻度と母親が子のお尻をたたく行動との関連:21世紀出生児縦断調査

    永吉真子、加藤承彦、可知悠子、越智真奈美、近藤天之、市瀬雄一、竹原健二

    第81回日本公衆衛生学会総会  2022.10.9  一般社団法人 日本公衆衛生学会

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    Event date: 2022.10

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:甲府  

  3. ストレス対処行動とがん発症との関係:J-MICC研究

    永吉 真子、竹内 研時、玉田 雄大、加藤 泰文、久保 陽子、 岡田 理恵子、田村 高志、菱田 朝陽、若井 建志、for the J-MICC Study Group

    第32回日本疫学会学術総会  2022.1.26  (一社)日本疫学会

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    Event date: 2022.1

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:オンライン  

  4. 遺伝要因、立ち直りの早さを含めたSOCの関連要因に関する検討の試み: J-MICC研究(静岡地区)

    永吉真子, 吉岡暁子, 都築陽祐, 菱田朝陽, 竹内研時, 加藤泰文, 久保陽子, 岡田理恵子, 松永貴史, 野畑俊介, 田村高志, 若井建志, for the J-MICC, Study Group

    第35回日本疫学会学術総会  2025.2.14 

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    Event date: 2025.2

    Language:Japanese   Presentation type:Poster presentation  

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  5. 親の雇用形態と、同居の子どものこころの健康状態との関連:国民生活基礎調査より

    永吉真子, 加藤承彦

    第83回日本公衆衛生学会総会  2024.10.30 

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    Event date: 2024.10

    Language:Japanese   Presentation type:Oral presentation (general)  

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Research Project for Joint Research, Competitive Funding, etc. 5

  1. わが国における父親の子育て支援を推進するための科学的根拠の提示と支援プログラムの提案に関する研究

    Grant number:20DA1002  2020.4 - 2023.3

    厚生労働科学研究費補助金  疾病・障害対策研究分野 成育疾患克服等次世代育成基盤研究

    竹原健二、加藤承彦、可知悠子、小崎恭弘、髙木悦子、立花良之、永吉真子、越智真奈美、阿川勇太、小河邦雄、Olukunmi O Balogun、片岡 智恵美、近藤 天之、須藤 茉衣子、芹澤 優子、新村 美知、Bibha Dhungel、水本 深喜

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    Authorship:Other  Grant type:Competitive

    Grant amount:\18627000 ( Direct Cost: \18627000 )

  2. 高齢者の口腔機能と施設入所・死亡との関係に関する地域疫学研究ー日常生活に環境と習慣(人と人とのつながり・発声頻度・咀嚼)は予後に影響を与えるかー

    Grant number:20-02-10  2020.4 - 2021.3

    公益財団法人8020推進財団  8020推進財団公募研究事業  令和2年度8020公募研究課題

    永吉真子、竹内 研時、前田 隆浩

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\650000 ( Direct Cost: \650000 )

  3. 高齢者サロンでの活動内容と味覚・口腔機能・生活圏域の変化との関連

    2019.4 - 2020.3

    公益財団法人サッポロ生物科学振興財団  サッポロ生物科学振興財団 第8回(2019年度)研究助成 

    永吉真子

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\700000 ( Direct Cost: \700000 )

  4. 管理的立場にある市町村の 保健師の人材育成に関する研究

    Grant number:H29-健危-一般-001  2017.4 - 2019.3

    厚生科学研究費補助金  厚生科学特別研究事業(健康安全・危機管理対策総合研究事業)  厚生労働科学研究費補助金

    成木弘子、吉岡京子、丸谷美紀、永吉真子、高橋秀人、横山徹爾、小島亜未、大澤絵里、松本珠実、森永由美子

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\3856000 ( Direct Cost: \3856000 )

  5. 起床時不整脈に及ぼす睡眠呼吸障害の影響についての横断研究

    2012.7 - 2013.3

    財団法人 大阪難病研究財団   医学研究助成 

    永吉 真子

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\1000000 ( Direct Cost: \1000000 )

KAKENHI (Grants-in-Aid for Scientific Research) 10

  1. Association of precarious employment and job insecurity and next-generation health and developmental environment and its buffering factors

    Grant number:23H04439  2023.4 - 2025.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Transformative Research Areas (A)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\2600000 ( Direct Cost: \2000000 、 Indirect Cost:\600000 )

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  2. Influence of Stress Resilience and Determinants of Resilience in the Development of Type 2 Diabetes in Japanese

    Grant number:22K10554  2022.4 - 2025.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

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  3. Association between social networks and oral frailty among community-dwelling elderlies in islands in Japan

    Grant number:16H06240  2016.4 - 2019.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Young Scientists (A)

    Nagayoshi Mako, Maeda Takahiro, Tamai Mami, Yamanashi Hirotomo, Koyamatsu Jun, Noguchi Towako, Nakano Namie

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    Authorship:Principal investigator 

    Grant amount:\11050000 ( Direct Cost: \8500000 、 Indirect Cost:\2550000 )

    The aim of this study was to evaluate influence of social environment including social networks on maximum tongue pressure as an important oral function among all elderly residents of communities in islands in Japan.
    This study provides a basis for prevention of oral frailty, including distributions of high/low maximum tongue pressure and social network sizes in the residents, and epidemiological evidence of association of the two.
    In this study population, size of social network and frequency of making voice in daily life would be important factors for stronger maximum tongue pressure. The result of the study suggests the importance of social networks and daily behavior for maintaining oral function, which would raise awareness about various way to prevent oral frailty and subsequent dysphagia/aspiration pneumonia. Future studies could examine causal relationships and generalizability of the associations should be examined in future studies.

  4. The relationship between chronotype and obesity and depression: Mendelian randomization analysis

    Grant number:24K13438  2024.4 - 2027.3

    Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Coinvestigator(s) 

  5. Construction of integrated risk model for gastrointestinal and lung cancers based on genomic information and blood biomarkers

    Grant number:23K09646  2023.4 - 2026.3

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

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    Authorship:Coinvestigator(s)  Grant type:Competitive

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Teaching Experience (On-campus) 19

  1. Cancer Prevention Promotion Course(Next-Generation Cancer Professional Development Program)

    2024

  2. 基礎医学セミナー

    2024

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    学部3年生を対象に、5か月間研究室に所属し研究を実施してもらうことを目的とする。
    疫学的な視点、研究の進め方、文献検索方法、SPSSによる解析手法、解析結果の解釈、発表資料の作成方法、発表方法について指導を行った。

  3. Young Leaders Program (Epidemiology & Biostatistics)

    2024

  4. 疫学と予防医学(4年生)

    2024

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    医学部4年生を対象とした科目「疫学と予防医学」のうち「疾患予防と健康施策」「スクリーニング」と「医推計学」のうち「計数データの検定」に関する講義を行った。

  5. 疫学と予防医学(2年生)

    2024

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    医学部2年生を対象とした科目「疫学と予防医学」のうち「疾患予防と健康施策」「スクリーニング」と「医推計学」のうち「計数データの検定」に関する講義を行った。

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Social Contribution 6

  1. Keep our and future generations' health - What are the social determinants that affect our health?

    Role(s):Appearance, Lecturer

    The 105th Meidai Cafe  Online  2024.7

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    Audience: Schoolchildren, Junior students, High school students, College students, Graduate students, Teachers, Guardians, Researchesrs, General, Scientific, Company, Civic organization, Governmental agency, Media

    Type:Science cafe

  2. 生活習慣と健康づくり

    Role(s):Lecturer

    大府市健康増進課  令和6年度おおぶ健康づくりボランティア養成講座  2024.6

  3. Lifestyle and Health Promotion

    Role(s):Lecturer

    Obu City  2023.6

  4. Prevention of metabolic syndrome and frailty: Lifestyle and social participation create health.

    Role(s):Lecturer

    2023.1 - 2023.3

  5. Lifestyle and Health Promotion

    Role(s):Lecturer

    Obu City  2022.6

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Media Coverage 4

  1. 父親の家事育児参加で母親の「あの体罰」が減少… 名古屋大大学院など共同研究 Newspaper, magazine

    中日新聞  中日新聞  2024.7

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    Author:Other 

    父親が家事、育児を行う頻度が高いと、母親が子どもに対してお尻をたたく頻度が減る可能性があることを、名古屋大大学院医学系研究科の永吉真子講師(予防医学)らの研究グループが明らかにした。父親が家事や育児に積極的に関わることが、母親のストレスや子育て環境の改善につながる可能性があるとしている。

    お尻をたたく行動は体罰の一つで、子どもの脳の発達や行動に長期にわたって悪影響を与えるため、その予防が必要とされている。
     研究では、国が2010年5月に国内で...

  2. 子へのお尻たたき、父の家事育児次第? 名大院など調査 Internet

    中日BIZナビ  中日BIZナビ  2024.7

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    Author:Other 

  3. 父親が家事育児を行うと、子どものお尻をたたく母親が減る? 研究グループが調査 名古屋 Internet

    名古屋テレビ放送株式会社  メーテレ  2024.7

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    Author:Other 

  4. 父の育児、母の子へのお尻たたき行動を減らす 関連評価は世界初 名大調査 Internet

    文教速報デジタル版  官庁通信デジタル  2024.7

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    Author:Other