Updated on 2020/04/24

写真a

 
NAGATA Kenichi
 
Organization
Graduate School of Medicine Designated assistant professor
Title
Designated assistant professor

Degree 1

  1. 博士(医学) ( 2010.6   大阪市立大学 ) 

Research Areas 2

  1. Life Science / Anatomy and histopathology of nervous system

  2. Life Science / Anatomy

Education 3

  1. Osaka City University   Graduate School, Division of Medicine

    2006.4 - 2010.3

      More details

    Country: Japan

  2. Osaka City University   Graduate School, Division of Medicine

    2004.4 - 2006.3

      More details

    Country: Japan

  3. Hiroshima University   Faculty of General Science

    2000.4 - 2004.3

      More details

    Country: Japan

Professional Memberships 3

  1. 日本人類遺伝学会

  2. 日本解剖学会

  3. 日本ゲノム編集学会

 

Papers 10

  1. Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID Reviewed

    Sasaguri H#, Nagata K# (contributed equally), Sekiguchi M, Fujioka R, Matsuba Y, Hashimoto S, Sato K, Kurup D, Yokota T, Saido TC.

        2018.7

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-018-05262-w

  2. DNA methylation level of the neprilysin promoter in Alzheimer's disease brains Reviewed

    Nagata K* (co-corresponding), Mano T, Murayama S, Saido TC, Iwata A*

        2018.5

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neulet.2018.01.003

  3. Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology Reviewed

    Nagata K* (co-corresponding), Takahashi M, Matsuba Y, Okuyama-Uchimura F, Sato K, Hashimoto S, Saito T, and Saido TC*

        2018.5

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41467-018-04238-0

  4. Distinct functional consequences of ECEL1/DINE missense mutations in the pathogenesis of congenital contracture disorders Reviewed

    Nagata K* (co-corresponding), Takahashi M, Kiryu-Seo S, Kiyama H* and Saido TC*

        2017.11

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40478-017-0486-9

  5. Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease Reviewed

    Mano T, Nagata K, Nonaka T, Tarutani A, Imamura T, Hashimoto T, Bannai T, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamasaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido TC, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A

    Proc Natl Acad Sci U S A     2017.11

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1073/pnas.1707151114

  6. ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis Reviewed

    Nagata K*(co-corresponding), Kiryu-Seo S, Tamada H, Okuyama-Uchimura F, Kiyama H*, Saido TC*

    Acta Neuropathologica     2016.7

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1007/s00401-016-1554-0

  7. Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation Reviewed

    Iwata A, Nagata K, Hatsuta H, Takuma H, Bundo M, Iwamoto K, Tamaoka A, Murayama S, Saido T, Tsuji S

    Human Molecular Genetics     2014.2

     More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/hmg/ddt451

  8. microRNA-124 is down regulated in nerve-injured motor neurons and it potentially targets mRNAs for KLF6 and STAT3 Reviewed

    Nagata K# (contributed equally), Hama I#, Kiryu-Seo S, Kiyama H

    Neuroscience     2014.1

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neuroscience.2013.10.055

  9. Damage-induced neuronal endopeptidase is critical for presynaptic formation of neuromuscular junctions Reviewed

    Nagata K, Kiryu-Seo S, Maeda M, Yoshida K, Morita T, Kiyama H

    Journal of Neuroscience     2010.5

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1523/JNEUROSCI.4521-09.2010

  10. Localization and ontogeny of damage-induced neuronal endopeptidase mRNA-expressing neurons in the rat nervous system Reviewed

    Nagata K, Kiryu-Seo S, Kiyama H

    Neuroscience   Vol. 141 ( 1 ) page: 299-310   2006.8

     More details

    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

▼display all

KAKENHI (Grants-in-Aid for Scientific Research) 3

  1. ECEL1/DINE遺伝子変異による先天性関節拘縮症発症メカニズムの解明

    2018.4 - 2021.3

    科学研究費補助金 

      More details

    Authorship:Principal investigator 

  2. DINE欠損運動神経の骨格筋支配における発生学的異常の解析

    2014.4 - 2017.3

    科学研究費補助金  若手研究(B)

      More details

    Authorship:Principal investigator 

  3. 神経再生関連microRNAの探索および機能解析

    2010.9 - 2011.3

    科学研究費補助金  研究活動スタート支援

      More details

    Authorship:Principal investigator