Organization
Graduate School of Medicine Center for Research of Laboratory Animals and Medical Research Engineering Division for Advanced Medical Research Designated lecturer
Title
Designated lecturer
Homepage
NAGATA Kenichi
Degree 1
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博士（医学） （ 2010.6 大阪市立大学 ）
Research Areas 2
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Life Science / Anatomy and histopathology of nervous system
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Life Science / Anatomy
Education 3
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Osaka City University Graduate School, Division of Medicine
2006.4 - 2010.3
Country： Japan
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Osaka City University Graduate School, Division of Medicine
2004.4 - 2006.3
Country： Japan
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Hiroshima University Faculty of General Science
2000.4 - 2004.3
Country： Japan
Professional Memberships 3
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日本ゲノム編集学会
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日本解剖学会
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日本人類遺伝学会
Papers 10
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Introduction of pathogenic mutations into the mouse Psen1 gene by Base Editor and Target-AID Reviewed
Sasaguri H#, Nagata K# (contributed equally), Sekiguchi M, Fujioka R, Matsuba Y, Hashimoto S, Sato K, Kurup D, Yokota T, Saido TC.
2018.7
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DNA methylation level of the neprilysin promoter in Alzheimer's disease brains Reviewed
Nagata K* (co-corresponding), Mano T, Murayama S, Saido TC, Iwata A*
2018.5
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Generation of App knock-in mice reveals deletion mutations protective against Alzheimer's disease-like pathology Reviewed
Nagata K* (co-corresponding), Takahashi M, Matsuba Y, Okuyama-Uchimura F, Sato K, Hashimoto S, Saito T, and Saido TC*
2018.5
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Distinct functional consequences of ECEL1/DINE missense mutations in the pathogenesis of congenital contracture disorders Reviewed
Nagata K* (co-corresponding), Takahashi M, Kiryu-Seo S, Kiyama H* and Saido TC*
2017.11
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Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease Reviewed
Mano T, Nagata K, Nonaka T, Tarutani A, Imamura T, Hashimoto T, Bannai T, Koshi-Mano K, Tsuchida T, Ohtomo R, Takahashi-Fujigasaki J, Yamashita S, Ohyagi Y, Yamasaki R, Tsuji S, Tamaoka A, Ikeuchi T, Saido TC, Iwatsubo T, Ushijima T, Murayama S, Hasegawa M, Iwata A
Proc Natl Acad Sci U S A 2017.11
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ECEL1 mutation implicates impaired axonal arborization of motor nerves in the pathogenesis of distal arthrogryposis Reviewed
Nagata K*(co-corresponding), Kiryu-Seo S, Tamada H, Okuyama-Uchimura F, Kiyama H*, Saido TC*
Acta Neuropathologica 2016.7
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Altered CpG methylation in sporadic Alzheimer's disease is associated with APP and MAPT dysregulation Reviewed
Iwata A, Nagata K, Hatsuta H, Takuma H, Bundo M, Iwamoto K, Tamaoka A, Murayama S, Saido T, Tsuji S
Human Molecular Genetics 2014.2
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microRNA-124 is down regulated in nerve-injured motor neurons and it potentially targets mRNAs for KLF6 and STAT3 Reviewed
Nagata K# (contributed equally), Hama I#, Kiryu-Seo S, Kiyama H
Neuroscience 2014.1
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Damage-induced neuronal endopeptidase is critical for presynaptic formation of neuromuscular junctions Reviewed
Nagata K, Kiryu-Seo S, Maeda M, Yoshida K, Morita T, Kiyama H
Journal of Neuroscience 2010.5
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Localization and ontogeny of damage-induced neuronal endopeptidase mRNA-expressing neurons in the rat nervous system Reviewed
Nagata K, Kiryu-Seo S, Kiyama H
Neuroscience Vol. 141 ( 1 ) page： 299-310 2006.8
KAKENHI (Grants-in-Aid for Scientific Research) 3
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ECEL1/DINE遺伝子変異による先天性関節拘縮症発症メカニズムの解明
2018.4 - 2021.3
科学研究費補助金
Authorship：Principal investigator
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DINE欠損運動神経の骨格筋支配における発生学的異常の解析
2014.4 - 2017.3
科学研究費補助金 若手研究(B)
Authorship：Principal investigator
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神経再生関連microRNAの探索および機能解析
2010.9 - 2011.3
科学研究費補助金 研究活動スタート支援
Authorship：Principal investigator