Faculty Profiles - TAKEGAMI Yasuhiko

Papers - TAKEGAMI Yasuhiko

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Computed tomography-based navigation versus accelerometer-based portable navigation in total hip arthroplasty for dysplastic hip osteoarthritis

Tanaka, S; Osawa, Y; Takegami, Y; Funahashi, H; Ido, H; Asamoto, T; Imagama, S

EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY AND TRAUMATOLOGY Vol. 35 ( 1 ) page： 83 2025.3

Fatty infiltration of periarticular muscles in patients with osteonecrosis of the femoral head

Otaka, K; Osawa, Y; Takegami, Y; Iida, H; Funahashi, H; Imagama, S

INTERNATIONAL ORTHOPAEDICS 2025.2

Language：English Publishing type：Research paper (scientific journal) Publisher：International Orthopaedics

Purpose: Muscle mass and fatty infiltration can be assessed on computed tomography (CT) images using the cross-sectional area (CSA) and computed tomography attenuation value (CTV). Femoral head collapse in osteonecrosis of the femoral head (ONFH) may affect both values. We investigated factors influencing the CSA and CTV of the periarticular muscles in patients with ONFH. Methods: Overall, 101 patients with ONFH with unilateral hip pain (stage 2, 24 patients; stage 3 A, 49 patients; and stage 3B, 28 patients) were included. The CSA and mean CTV of the bilateral gluteus maximus (Gmax), gluteus medius (Gmed), gluteus minimus (Gmin), and iliopsoas (IP) muscles were measured using CT cross-sections. Bilateral comparisons and associations with Japanese Investigation Committee (JIC) stage were analysed. Multiple regression analysis was used to evaluate factors associated with the CSA and CTV. Results: On the symptomatic side, the CSA was significantly lower for the Gmax, Gmed, and IP, whereas the CTV was significantly lower for all tested muscles (all p < 0.01). The CTV, but not the CSA, of the Gmax, Gmed, and Gmin was significantly associated with the JIC stage severity bilaterally (all p < 0.01). Multiple regression analysis showed significant associations of the CTV with age, sex, and JIC stage (all p < 0.01). Conclusion: Symptomatic ONFH leads to decreased muscle mass and increased fatty infiltration. Femoral head collapse progression is associated with a decrease in the CTV. Periarticular muscle assessment, including on the contralateral side, is important in patients with ONFH, particularly in older women.

DOI： 10.1007/s00264-025-06457-9

Web of Science

Scopus

PubMed

特集股関節温存手術-寛骨臼側股関節周囲骨切り術- 偏心性寛骨臼回転骨切り術のピットフォール

大澤郁介, 竹上靖彦, 船橋洋人, 今釜史郎

関節外科　基礎と臨床 Vol. 44 ( 2 ) page： 131 - 138 2025.2

Discrepancy between radiography and magnetic resonance imaging in Japanese Investigation Committee classification type C osteonecrosis of the femoral head.

Otaka K, Osawa Y, Takegami Y, Funahashi H, Imagama S

International orthopaedics Vol. 49 ( 2 ) page： 391 - 397 2025.2

Discrepancy between radiography and magnetic resonance imaging in Japanese Investigation Committee classification type C osteonecrosis of the femoral head

Otaka, K; Osawa, Y; Takegami, Y; Funahashi, H; Imagama, S

INTERNATIONAL ORTHOPAEDICS Vol. 49 ( 2 ) page： 391 - 397 2025.2

Discrepancy between radiography and magnetic resonance imaging in Japanese Investigation Committee classification type C osteonecrosis of the femoral head

Otaka, K; Osawa, Y; Takegami, Y; Funahashi, H; Imagama, S

INTERNATIONAL ORTHOPAEDICS Vol. 49 ( 2 ) page： 391 - 397 2025.2

Discrepancy between radiography and magnetic resonance imaging in Japanese Investigation Committee classification type C osteonecrosis of the femoral head Open Access

Otaka K., Osawa Y., Takegami Y., Funahashi H., Imagama S.

International Orthopaedics Vol. 49 ( 2 ) page： 391 - 397 2025.2

Language：English Publishing type：Research paper (scientific journal) Publisher：International Orthopaedics

Purpose: The Japanese Investigation Committee (JIC) classification for osteonecrosis of the femoral head (ONFH) is based on the necrotic area relative to the weight-bearing surface on anteroposterior (AP) radiographs or central coronal MRI. Discrepancies exist between these methods, potentially related to the AP necrosis area. This study evaluated these discrepancies and the extent of AP necrotic lesions. Methods: We retrospectively reviewed 139 patients (188 hips) with nontraumatic ONFH, JIC type C1 or C2 on radiography, and collapse < 3 mm. Cases with and without discrepancies between radiography and MRI were designated as discrepancy and consistent groups, respectively. We assessed the proportion of patients in the discrepancy group and survival rates in both groups, with femoral head collapse > 3 mm as the endpoint. The cutoff value for AP necrotic regions on lateral radiographs identifying discrepancies was calculated using ROC curve analysis. Results: The discrepancy group comprised 28 hips (14.9%) vs. 160 hips in the consistent group. Five-year survival rates were 73.3% vs. 31.9% (P < 0.01), and AP necrotic region extent was 61.2 vs. 73.8 mm (P < 0.001) in discrepancy vs. consistent groups. The cutoff value for necrotic region extent revealing discrepancies was 66.9% (AUC 0.833, sensitivity 83.8%, specificity 82.4%). Conclusion: Patients with AP necrotic regions < 66.9% were more likely to show discrepancies between radiography and MRI in type classification. This study can help improve accuracy in assessing ONFH severity and prognosis.

DOI： 10.1007/s00264-024-06396-x

Open Access

Scopus

A Case of Successful Perioperative Rehabilitation in Two-Stage Revision Total Hip Arthroplasty for an Intraoperative Acetabular Fracture: Insights Into Interim-Period Rehabilitation Strategies.

Nojiri S, Osawa Y, Tanaka S, Takegami Y

Cureus Vol. 17 ( 2 ) page： e78619 2025.2

連載最新原著レビュー大腿骨頭壊死における圧潰停止は骨頭前後の壊死範囲と関連する

大澤郁介, 関泰輔, 竹上靖彦, 今釜史郎

整形外科 Vol. 76 ( 1 ) page： 89 - 93 2025.1

地域在住高齢者の転倒と転倒予防〜ロコモティブシンドロームおよび脊椎グローバルアライメントの観点から〜 Reviewed

世木直喜, 中島宏彰, 伊藤定之, 大内田隼, 飯田浩貴, 竹上靖彦, 田中智史, 両角正義, 村本明生, 小林和克, 石塚真哉, 関泰輔, 長谷川幸治, 今釜史郎

日本転倒予防学会誌 Vol. 10 ( 1 ) page： 19 - 25 2024.3

Early Recovery of Physical Function After Total Hip Arthroplasty in a Patient With Osteopetrosis: A Case Report Reviewed

Nojiri, S; Kayamoto, A; Terai, C; Osawa, Y; Takegami, Y

CUREUS JOURNAL OF MEDICAL SCIENCE Vol. 16 ( 1 ) page： e52293 2024.1

Factors affecting return to sports after eccentric rotational acetabular osteotomy Open Access

Osawa Y., Seki T., Takegami Y., Makida K., Ochiai S., Hasegawa Y., Imagama S.

Revue de Chirurgie Orthopedique et Traumatologique Vol. 109 ( 4 ) 2023.6

Language：English Publishing type：Research paper (scientific journal) Publisher：Revue de Chirurgie Orthopedique et Traumatologique

Background: Although eccentric acetabular rotation osteotomy (ERAO) is an effective treatment for developmental dysplasia of the hip (DDH), there is little information about return to sports after ERAO. This study aimed to investigate 1) the patient factors that influence the return to sports after ERAO, 2) whether postoperative sports participation will affect future osteoarthritis progression. Hypothesis: Some factors affect the return to sports after ERAO. Patients and methods: Of 503 patients who underwent ERAO from 1990 to 2010, 124 who had been continuously participating in sports preoperatively (average 13.2 years after surgery) were included. Patient demographics of sex, age, body mass index, unilateral to bilateral case ratio, history of treatment for childhood DDH, preoperative Kellgren-Lawrence (KL) grade, center edge angle, joint congruency, Harris hip score, complications and the survival rate were compared between the S group (patients who participated in the same sports preoperatively) and N group (patients who could not participate in sports postoperatively). Results: Seventy-two (58%) and 52 patients (42%) in the S and N groups, respectively, had an overall return to sports rate of 64% (79 patients). The most common sports that patients participated in were swimming (30 patients [24%]), jogging (12 [10%]), and golf (10 [8%]) preoperatively, and swimming (14 patients [11%]), golf (8 [6%]), and jogging (8 [6%]) postoperatively. There were no significant differences between both groups in terms of sex, age, body mass index, unilateral to bilateral case ratio, history of treatment for childhood DDH, preoperative KL grade, and joint congruency. There was a significant difference in patient factors between the S (11 joints [14%]) and N (20 joints [38%]) groups only when the preoperative center edge angle was < 0°. There was no significant difference in the preoperative Harris hip score and the final survey between the S (73.2 ± 4.6 and 93.4 ± 7.2) and N (72.5 ± 4.8 and 92.1 ± 7.4) groups. Complications showed no significant differences between the five patients (7%) in the S group and six patients (13%) in the N group. The KL grade progressed in 10 cases (grade II to III in 2 cases and grade III to IV in 8) in the S group and 8 cases (grade II to III in 1 case and grade III to IV in 7 cases) in the N group. The 10-year and 20-year joint survival rates with THA conversion as the endpoint were 98.1% (95% CI: 87.4%–99.7%) and 83.7% (95% CI: 62.6%–93.4%) in the S group and 100% (95% CI: 70.7%–99.3%) and 95.2% (95% CI: 12.6%–92.6%) in the N group, respectively. In the evaluation of factors affecting sports return by logistic regression analysis, only one significant factor (odds ratio 3.42, 95% confidence interval: 1.58–7.42, p < 0.01) was the preoperative center edge angle < 0°. Discussion: The chief factor affecting the return to sports after surgery was a preoperative center edge angle < 0°; moreover, the continuation of sports did not affect the subsequent progression of osteoarthritis or THA conversion. Level of evidence: Level III, cohort study.

DOI： 10.1016/j.rcot.2022.10.006

Scopus

Re: Shibata et al. Comparison of surgical treatments for distal ulna fracture when combined with anterior locking plate fixation of the distal radius in the over 70 age group. J Hand Surg Eur. Epub ahead of print 28 January 2023. DOI: 10.1177/17531934221150495 Invited Reviewed

Shibata, R; Tokutake, K; Takegami, Y; Natsume, T; Matsubara, Y; Imagama, S

JOURNAL OF HAND SURGERY-EUROPEAN VOLUME 2023.4

人工股関節全置換術術後のPelvic obliquityは術前の腰椎側屈可動性と関連している Reviewed

小澤悠人, 大澤郁介, 竹上靖彦, 船橋洋人

日本関節病学会誌 Vol. 42 ( 1 ) page： 12 - 21 2023

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：日本関節病学会

目的：側方骨盤傾斜は変形性膝関節症や変形性腰椎症などの隣接椎間障害や自覚的な脚長差を生じることからQOLを障害する因子の一つとして知られている。変形性股関節症では脚長差や可動域制限により側方骨盤傾斜を呈することが少なくなく，ときとして人工股関節置換術（以下THA）後でも側方骨盤傾斜の改善が得られない症例が存在する。本研究の目的はTHA後の側方骨盤傾斜を認めない症例と残存する症例を比較し，術後側方骨盤傾斜に影響を与える因子について調査することである。症例および方法：単一施設後ろ向きコホート研究にて，2018年6月から2020年7月までに片側THAを行った91股を対象とした。これらの症例をTHA後の側方骨盤傾斜が2°以内であった48例（以下F群）と2°以上であった43例（以下O群）に分けた。調査項目は年齢，性別，身長，体重，Body Mass Index，術前後のHarris hip score（以下HHS），術前後の股関節可動域，術前後の自覚的脚長差の有無，術前後の側方骨盤傾斜，脚長差，オフセット，術前腰椎側屈可動性について両群間で比較検討を行い，多変量解析を用いて術後の側方骨盤傾斜に影響する因子を評価した。結果：年齢，性別，身長，体重，BMIは両群で有意差を認めなかった。術前のHHSは両群で有意差を認めなかったが，術後1年でのHHSはF群90.8±7.6に対してO群86.4±11.0で有意にO群が不良であった。術前自覚的脚長差には両群で有意差を認めなかったが術後の自覚的脚長差認識率はF群で20.8%，O群で51.1%と有意にO群で自覚的脚長差を有する症例が多かった。術前後の画像的な脚長差は両群で有意差を認めなかった。術前の腰椎側屈可動性はF群で8.7±4.3°，O群で6.9±4.9°で有意にO群が不良であった。多変量解析の結果では術前側方骨盤傾斜と術前の腰椎側屈可動性が術後の側方骨盤傾斜≧2°の有意なリスク因子であった。結論：術前の側方骨盤傾斜が大きい症例や腰椎可動性が不良な症例ではTHA後の側方骨盤傾斜が残存するリスクが高く，慎重な術前計画が必要である。

DOI： 10.11551/jsjd.42.12

CiNii Research

荷重部の後方壊死範囲が大腿骨頭壊死の圧潰停止に影響する Reviewed

大澤郁介, 関泰輔, 竹上靖彦, 加藤大策, 竹本元大

日本関節病学会誌 Vol. 41 ( 4 ) page： 275 - 279 2022

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：日本関節病学会

目的：圧潰をきたした大腿骨頭壊死が自然経過において圧潰停止し，長期的に手術治療を回避できることは少なくない。我々は骨頭後方の壊死領域の範囲が大腿骨頭壊死の圧潰停止に関与すると仮説し，後方壊死領域と圧潰停止の関係性について調査した。対象および方法：2010年から2016年までに当院に初回受診した片側症状かつ圧潰が3mm以内（Stage 3A）の大腿骨頭壊死77例を対象とした。性別は男性37例，女性40例で平均年齢は45.1歳，平均観察期間は48.7か月，Type分類（B/C1/C2）は3/35/39であった。調査項目は圧潰停止の有無，骨頭後方壊死領域とした。圧潰停止は初診から2年時点で3mm以内の圧潰にとどまった場合に圧潰停止と定義した。骨頭後方壊死領域はMRI横断面で骨頭後方1/3レベルの冠状断T1 MRIにおける荷重面おける壊死領域の割合を評価した。ROC曲線を用いて圧潰停止が得られる後方壊死領域のcut off値を割り出し，cut off値より圧潰進行（>3mm）および人工股関節全置換術をendpointとした生存率を評価した。結果：圧潰停止は31例（40%）に認めた。後方壊死域は圧潰停止例43.1±31.8%に対して圧潰進行例95.6±19.1%で有意差を認めた（P<0.01）。ROC曲線のAUCは0.946でcut off値は後方壊死領域68%（感度96%，特異度92%）であった。圧潰進行および人工股関節全置換術をendpointとした4年生存率は後方壊死領域>68%では6.9%および33%に対し，後方壊死領域<68%では96%および93%でいずれも有意差を認めた（P<0.01およびP<0.01）。結論：一旦圧潰をきたした大腿骨頭壊死においても後方壊死領域が2/3以下の症例は高い確率で自然経過による圧潰停止が期待でき，保存的治療を行うか判断する際の有効な指標となる。

DOI： 10.11551/jsjd.41.275

CiNii Research

Peroneural neuropathy after total hip arthroplasty with combined neural block: a case report Reviewed

KINUKAWA Tomoaki Alex, TAMURA Takahiro, TAKEGAMI Yasuhiko, SEKI Taisuke, NISHIWAKI Kimitoshi

Journal of Japan Society of Pain Clinicians Vol. 28 ( 9 ) page： 194 - 198 2021.9

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society of Pain Clinicians

A 46-year-old woman, 157 cm 58 kg, underwent left total hip arthroplasty after lumbar plexus block and sciatic nerve block via the parasacral approach. Postoperative X-ray revealed 20-mm leg extension. After surgery, both legs had movement disorder and sensory disturbance, which improved within a few hours. Lumbar plexus block was considered to be an epidural block. Thereafter, sensory and motor disorders slightly improved, but recovery of dorsiflexion movement of the left ankle joint was delayed and mild peroneal neuropathy at the level of the peroneal head was diagnosed by electromyography 28 days after surgery. Thirty-two days after surgery, the patient was discharged with stable walking using a cane. The neurological symptoms were suspected to be caused by physical factors, such as hyperextension of the peroneal nerve, because the neuropathy was at the level of the peroneum. We also cannot exclude the possibility that this nerve block affected paralysis.

DOI： 10.11321/jjspc.21-0029

CiNii Research

論説多施設共同研究による脛骨骨幹部骨折に対する髄内釘固定術の成績 Reviewed

等々力一徳, 竹上靖彦, 川﨑成美, 上見亮太, 山田梨沙, 三島健一, 今釜史郎

整形外科 Vol. 72 ( 4 ) page： 301 - 305 2021.4

CIRCULATING MIR-34 IS ASSOCIATED WITH THE DEVELOPMENT OF KNEE OSTEOARTHRITIS IN COMMUNITY-DWELLING OLDER MEN Reviewed International journal

Takegami, Y; Seki, T; Ishizuka, S; Suzuki, K; Fujii, R; Hasegawa, Y; Imagama, S

OSTEOARTHRITIS AND CARTILAGE Vol. 29 page： S156 - S156 2021.4

Long-term outcomes of curved intertrochanteric varus osteotomy combined with bone impaction grafting for non-traumatic osteonecrosis of the femoral head. Reviewed

Osawa Y, Seki T, Okura T, Takegami Y, Ishiguro N, Hasegawa Y

The bone & joint journal Vol. 103-B ( 4 ) page： 665 - 671 2021.4

Long-term outcomes of curved intertrochanteric varus osteotomy combined with bone impaction grafting for non-traumatic osteonecrosis of the femoral head Reviewed

Osawa Y., Seki T., Okura T., Takegami Y., Ishiguro N., Hasegawa Y.

BONE & JOINT JOURNAL Vol. 103B ( 4 ) page： 665 - 671 2021.4

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Papers - TAKEGAMI Yasuhiko